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| 1 | Role of endoscopic ultrasonography in the loco-regional staging of patients with rectal cancer显示文摘The prognosis of rectal cancer(RC) is strictly related to both T and N stage of the disease at the time of diagnosis. RC staging is crucial for choosing the best multimodal therapy: patients with high risk locally advanced RC(LARC) undergo surgery after neoadjuvant chemotherapy and radiotherapy(NAT); those with low risk LARC are operated on after a preoperative short-course radiation therapy; finally, surgery alone is recommended only for early RC. Several imaging methods are used for staging patients with RC: computerized tomography, magnetic resonance imaging, positron emission tomography, and endoscopic ultrasound(EUS). EUS is highly accurate for the loco-regional staging of RC, since it is capable to evaluate precisely the mural infiltration of the tumor(T), especially in early RC. On the other hand, EUS is less accurate in restaging RC after NAT and before surgery. Finally, EUS is indicated for follow-up of patients operated on for RC, where there is a need for the surveillance of the anastomosis. The aim of this review is to highlight the impact of EUS on the management of patients with RC, evaluating its role in both preoperative staging and follow-up of patients after surgery. | Pietro Marone Mario de Bellis Valentina D'Angelo Paolo Delrio Valentina Passananti Elena Di Girolamo Giovanni Battista Rossi Daniela Rega Maura Claire Tracey Alfonso Mario Tempesta | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，7： | 11 |
| 2 | Impaired coagulation,liver dysfunction and COVID-19:Discovering an intriguing relationship显示文摘Coronavirus disease 2019(COVID-19)is,at present,one of the most relevant global health problems.In the literature hepatic alterations have been described in COVID-19 patients,and they are mainly represented by worsening of underlying chronic liver disease leading to hepatic decompensation and liver failure with higher mortality.Several potential mechanisms used by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)to cause liver damage have been hypothesized.COVID-19 primary liver injury is less common than secondary liver injury.Most of the available data demonstrate how liver damage in SARSCo V-2 infection is likely due to systemic inflammation,and it is less likely mediated by a cytopathic effect directed on liver cells.Moreover,liver alterations could be caused by hypoxic injury and drugs(antibiotics and non-steroidal antiinflammatory drugs,remdesivir,tocilizumab,tofacitinib and dexamethasone).SARS-Co V-2 infection can induce multiple vascular district atherothrombosis by affecting simultaneously cerebral,coronary and peripheral vascular beds.Data in the literature highlight how the virus triggers an exaggerated immune response,which added to the cytopathic effect of the virus can induce endothelial damage and a prothrombotic dysregulation of hemostasis.This leads to a higher incidence of symptomatic and confirmed venous thrombosis and of pulmonary embolisms,especially in central,lobar or segmental pulmonary arteries,in COVID-19.There are currently fewer data for arterial thrombosis,while myocardial injury was identified in 7%-17%of patients hospitalized with SARS-Co V-2 infection and 22%-31%in the intensive care unit setting.Available data also revealed a higher occurrence of stroke and more serious forms of peripheral arterial disease in COVID-19 patients.Hemostasis dysregulation is observed during the COVID-19 course.Lower platelet count,mildly increased prothrombin time and increased Ddimer are typical laboratory features of patients with severe SARS-Co V-2 infection,described as“COVID-19 associated coagulopathy.”These alterations are correlated to poor outcomes.Moreover,patients with severe SARS-Co V-2 infection are characterized by high levels of von Willebrand factor with subsequent ADAMTS13 deficiency and impaired fibrinolysis.Platelet hyperreactivity,hypercoagulability and hypofibrinolysis during SARS-Co V-2 infection induce a pathological state named as“immuno-thromboinflammation.”Finally,liver dysfunction and coagulopathy are often observed at the same time in patients with COVID-19.The hypothesis that liver dysfunction could be mediated by microvascular thrombosis has been supported by postmortem findings and extensive vascular portal and sinusoidal thrombosis observation.Other evidence has shown a correlation between coagulation and liver damage in COVID-19,underlined by the transaminase association with coagulopathy,identified through laboratory markers such as prothrombin time,international normalized ratio,fibrinogen,D-dimer,fibrin/fibrinogen degradation products and platelet count.Other possible mechanisms like immunogenesis of COVID-19 damage or massive pericyte activation with consequent vessel wall fibrosis have been suggested. | Damiano D'Ardes Andrea Boccatonda Giulio Cocco Stefano Fabiani Ilaria Rossi Marco Bucci Maria Teresa Guagnano Cosima Schiavone Francesco Cipollone | 2022 | World Journal of Gastroenterology2022，28，11： | 5 |
| 3 | Habitual salt intake and risk of gastric cancer: A meta-analysis of prospective studies显示文摘 | Lanfranco D’Elia Giovanni Rossi Renato Ippolito Francesco P. Cappuccio Pasquale Strazzullo | 2012 | Clinical Nutrition2012，，4： | 3 |
| 4 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 5 | Maternal morbidity following a trial of labor after cesarean section vs elective repeat cesarean delivery: a systematic review with metaanalysis显示文摘 | A. Cristina Rossi Vincenzo D’Addario | 2008 | American Journal of Obstetrics and Gynecology2008，，3： | 2 |
| 6 | Orthostatic hypotension,an often-neglected problem in community-dwelling older people:discrepancies between studies and real life显示文摘Orthostatic hypotension (OH)is a common condition in older persons.According to the 2011criteria,OH is defined by a sustained reduction of systolic blood pressure of 20 mmHg or a 10mmHg-fall of diastolic blood pressure,[1] Its prevalence increases with age and according to a recent systematic review the pooled prevalence in community dwelling older people is 22.2%.[2]Although OH is largely explained by concurrent clinical conditions (in particular, hypertension,diabetes,malnutrition,vascular encephalopa- thy,anemia,Parkinson's disease)[3],aging per se determines a series of physiological dysfunctions potentially representing its biological substratum (e.g.,reduction in barore- flex-mediated cardiovascular function,altered salt and water balance at renal level,impaired cardiac diastolic filling).It is also noteworthy that age-related changes in pharmacokinetic and pharmacodynamic mechanisms of drugs (especially in the context of polypharmacy)also increase the risk of OH. | Sarah Damanti Dario Consormi Annalisa Valentini Benedetta Cerasoli Martina Biotto Federica Conti Marta Clerici Pasqualina Iannuzzi Emanuela Manzo Paolo D Rossi Simona Ciccone Matteo Cesari | 2018 | Journal of Geriatric Cardiology2018，15，10： | 2 |
| 7 | Comparison of contrast-enhanced ultrasonography versus baseline ultrasound and contrast-enhanced computed tomography in metastatic disease of the liver: diagnostic performance and confidence显示文摘 | Emilio Quaia Mirko D'Onofrio Alessandro Palumbo Stefania Rossi Stefano Bruni Maria Cova | 2006 | European Radiology2006，，7： | 2 |
| 8 | Orthostatic hypertension and adverse clinical outcomes in adults and older people显示文摘Orthostatic hypertension(OHT)is a condition characterized by an increase in blood pressure after assuming the standing position.[1]Nowadays no consensus definition exists,thus OHT prevalence varies among studies(4%-20.3%). | Sarah Damanti Paolo D Rossi Matteo Cesari | 2021 | Journal of Geriatric Cardiology2021，18，9： | 2 |
| 9 | Antithrombin III (ATILL) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study显示文摘 | F. Baudo T. M. Caimi F. deCataldo A. Ravizza S. Arlati G. Casella D. Carugo G. Palareti C. Legnani L. Ridolfi R. Rossi A. D’Angelo L. Crippa D. Giudici G. Gallioli A. Wolfler G. Calori | 1998 | Intensive Care Medicine1998，，4： | 2 |
| 10 | The object-oriented hypermedia design model显示文摘 | Schwabe D Rossi G | 1995 | Communications of the ACM1995，38，8： | 1 |
| 11 | Blow-up vs global existence for quasilinear parabolic systems with a nonlinear boundary condition显示文摘 | Aeosta G Rossi J D | 1997 | Z Angew Math Phys1997，48，： | 1 |
| 12 | Molecular heterogeneity of diffuse large B- cell lymphoma: implications for disease management and prognosis显示文摘 | Rossi D Gaidano G | 2002 | Hematology2002，7，4： | 1 |
| 13 | Numberof lymph nodemetastases and its prognostic significance in early gastric cancer: multicenter Italian study显示文摘 | Roviello F Rossi S Marrelli D | 2006 | J Surg Oncol2006，94，4： | 1 |
| 14 | Radioguided sentinel lymph node dissection in patients with Iocalised prostate carci- noma:influence of the dose of radiolabelled colloid to avoid failure of the procedure显示文摘 | Brenot Rossi I Rossi D Esterni B | 2008 | Eur J Nucl Med Mol Imaging2008，35，1： | 1 |
| 15 | Sequential changes in factorVIII and platelets preceding deep vein thrombosis in patients with spi-nal cord injury显示文摘 | Rossi EC Green D Rosen JS | 1980 | Br J Haematol1980，45，： | 1 |
| 16 | Functional siRNA exprssion from transfected PCR products显示文摘 | CASTANOTTO D LI H ROSSI J J | 2002 | RNA2002，8，： | 1 |
| 17 | The Displacement Field of the Landers Earthquake Mapped By Radar Interferometry显示文摘 | Massonnet D Rossi M Carmona C | 1993 | Nature1993，364，： | 1 |
| 18 | Cyclooxygenase-2 (COX-2) overexpression in meningiomas: real time PCR and immunohistochemistry显示文摘 | Buccoliero AM Castiglione F Rossi Degl'Innocenti D | 2007 | Appl Immunohistochem Mol Morphol2007，15，2： | 1 |
| 19 | Existence of periodic motions of a tether trailing satellite显示文摘 | Rossi E V Cicci D A Cochran J E Jr | | 0，，： | 1 |
| 20 | l Percutaneous radio-frequency interstitial thermal ablation in the treatment ofsmall hepatocellular carcinoma显示文摘 | Rossi S D iStasi M Buscarini E et a | 2005 | Cancer J Sci Am2005，，1： | 1 |
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