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| 1 | Enteric glial cells and their role in gastrointestinal motor abnormalities: Introducing the neuro-gliopathies显示文摘The role of enteric glial cells has somewhat changed from that of mere mechanical support elements, gluing together the various components of the enteric nervous system, to that of active participants in the complex interrelationships of the gut motor and inflammatory events. Due to their multiple functions, spanning from supporting elements in the myenteric plexuses to neurotransmitters, to neuronal homeostasis, to antigen presenting cells, this cell population has probably more intriguing abilities than previously thought. Recently, some evidence has been accumulating that shows how these cells may be involved in the pathophysiological aspects of some diseases. This review will deal with the properties of the enteric glial cells more strictly related to gastrointestinal motor function and the human pathological conditions in which these cells may play a role, suggesting the possibility of enteric neuro- gliopathies. | Gabrio Bassotti Vincenzo Villanacci Simona Fisogni Elisa Rossi Paola Baronio Carlo Clerici Christoph A Maurer Gieri Cathomas Elisabetta Antonelli | 2007 | World Journal of Gastroenterology2007,13,30: | 16 |
| 2 | Therapeutic options for the management of pancreatic cancer显示文摘Since its initial characterization, pancreatic ductal adenocarcinoma has remained one of the most devastating and difficult cancers to treat. Pancreatic cancer is the fourth leading cause of death in the United States, resulting in an estimated 38460 deaths annually. With few screening tools available to detect this disease at an early stage, 94% of patients will die within five years of diagnosis. Despite decades of research that have led to a better understanding of the molecular and cellular signaling pathways in pancreatic cancer cells, few effective therapies have been developed to target these pathways. Other treatment options have included more sophisticated pancreatic cancer surgeries and combination therapies. While outcomes have improved modestly for these patients, more effective treatmentsare desperately needed. One of the greatest challenges in the future of treating this malignancy will be to develop therapies that target the tumor microenvironment and surrounding pancreatic cancer stem cells in addition to pancreatic cancer cells. Recent advances in targeting pancreatic stellate cells and the stroma have encouraged researchers to shift their focus to the role of desmoplasia in pancreatic cancer pathobiology in the hopes of developing newer-generation therapies. By combining novel agents with current cytotoxic chemotherapies and radiation therapy and personalizing them to each patient based on specific biomarkers, the goal of prolonging a patient's life could be achieved. Here we review the most effective therapies that have been used for the treatment of pancreatic cancer and discuss the future potential of therapeutic options. | Maria L Rossi Azeem A Rehman Christopher S Gondi | 2014 | World Journal of Gastroenterology2014,20,32: | 13 |
| 3 | Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis显示文摘 | Tetsuya Ueda Stefano Volinia Hiroshi Okumura Masayoshi Shimizu Cristian Taccioli Simona Rossi Hansjuerg Alder Chang-gong Liu Naohide Oue Wataru Yasui Kazuhiro Yoshida Hiroki Sasaki Sachiyo Nomura Yasuyuki Seto Michio Kaminishi George A Calin Carlo M Croce | 2010 | Lancet Oncology2010,,2: | 4 |
| 4 | Assessment and impact of diastolic function by echocardiography in elderly patients显示文摘Doppler echocardiography 是为对心脏舒张的机能障碍的评价的标准答案,它逐渐地作为心失败的一个原因被认出,在特别老。用 Doppler echocardiography 技术的联合,识别心脏舒张的机能障碍的等级是可能的,估计左室的充满压力并且建立心脏舒张的机能障碍的慢性。这些导出 physiologically 的措施广泛地对左心压力的侵略大小被验证了并且被显示了在大量临床的背景预示地珍贵。这评论探索机制,并且来临到对心脏舒张的机能障碍的评价在老。为临床医生的挑战是从与正常变老联系的那些识别 pathophysiological 变化。当在联合,和花的很长时间使用了进报道时, Doppler echocardiographic 参数在对在更老的病人的 dyspnoea 的评价是有用的并且提供预示的卓见。 | Clementina Dugo Marzia Rigolli Andrea Rossi Gillian A Whalley | 2016 | Journal of Geriatric Cardiology2016,13,3: | 3 |
| 5 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018,26,4: | 3 |
| 6 | Orbital evolution aroud irregular bodies 显示文摘 | Rossi A Marzari F Farinella P | 1999 | Earth Planets Space1999,51,: | 2 |
| 7 | Hazard and population vulnerability analysis: a step towards landslide risk assessment显示文摘In this paper, an attempt to analyse landslide hazard and vulnerability in the municipality of Pahuatlán, Puebla, Mexico, is presented. In order to estimate landslide hazard, the susceptibility,magnitude(area-velocity ratio) and landslide frequency of the area of interest were produced based on information derived from a geomorphological landslide inventory; the latter was generated by using very high resolution satellite stereo pairs along with information derived from other sources(Google Earth,aerial photographs and historical information).Estimations of landslide susceptibility were determined by combining four statistical techniques:(i) logistic regression,(ii) quadratic discriminant analysis,(iii) linear discriminant analysis, and(iv)neuronal networks. A Digital Elevation Model(DEM)of 10 m spatial resolution was used to extract the slope angle, aspect, curvature, elevation and relief.These factors, in addition to land cover, lithology anddistance to faults, were used as explanatory variables for the susceptibility models. Additionally, a Poisson model was used to estimate landslide temporal frequency, at the same time as landslide magnitude was obtained by using the relationship between landslide area and the velocity of movements. Then,due to the complexity of evaluating it, vulnerability of population was analysed by applying the Spatial Approach to Vulnerability Assessment(SAVE) model which considered levels of exposure, sensitivity and lack of resilience. Results were expressed on maps on which different spatial patterns of levels of landslide hazard and vulnerability were found for the inhabited areas. It is noteworthy that the lack of optimal methodologies to estimate and quantify vulnerability is more notorious than that of hazard assessments.Consequently, levels of uncertainty linked to landslide risk assessment remain a challenge to be addressed. | Franny G.MURILLO-GARCíA Mauro ROSSI Francesca ARDIZZONE Federica FIORUCCI Irasema ALCáNTARA-AYALA | 2017 | Journal of Mountain Science2017,14,7: | 2 |
| 8 | Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis显示文摘 | Tetsuya Ueda Stefano Volinia Hiroshi Okumura Masayoshi Shimizu Cristian Taccioli Simona Rossi Hansjuerg Alder Chang-gong Liu Naohide Oue Wataru Yasui Kazuhiro Yoshida Hiroki Sasaki Sachiyo Nomura Yasuyuki Seto Michio Kaminishi George A Calin Carlo M Croce | 2010 | Lancet Oncology2010,,2: | 2 |
| 9 | Antiherpetic activity of a sulfated polysaccharide from Agaricus brasiliensis mycelia显示文摘 | Francielle Tramontini Gomes de Sousa Cardozo Carla Maísa Camelini Alessandra Mascarello Márcio José Rossi Ricardo José Nunes Célia Regina Monte Barardi Margarida Matos de Mendon?a Cláudia Maria Oliveira Sim?es | 2011 | Antiviral Research2011,,1: | 2 |
| 10 | 特发性肺间质纤维化患者疱疹病毒感染与血管重塑、肺高血压相关显示文摘肺高血压是特发性肺问质纤维化(idiopathic pulmonary fibrosis,IPF)的主要并发症,对患者预后有不良影响。目前认为疱疹病毒在IPF的发生发展过程中起致病作用。病毒对IPF相关的肺高血压的影响尚不清楚。该研究重点探讨病毒对IPF患者肺高血压相关方面的影响,同时还对γ疱疹病毒[鼠疱疹病毒68(maus herpesvirus 68,MHV-68)]诱发的肺间质纤维化实验室小鼠模型进行评估。 | Calabrese F Kipar A Lunardi F Balestro E Perissinotto E Rossi E Nannini N Marulli G Stewart JP Rea F 刘莉 叶鹏 | 2013 | 中华高血压杂志2013,21,5: | 2 |
| 11 | New insights in drug development for the non - small cell lung cancer therapy 显示文摘 | GRIDELLI C ROSSI A MAIONE P | 2008 | Front Biosci2008,13,: | 1 |
| 12 | 2-Week triple therapy for Helicobacter pylori infection is better than 1-week in clinical Practice: a large prospective single-center randomized st udy显示文摘 | Paoluzi P Iacopini F Crispino P Nardi F Bella A Rivera M Rossi P Gurnari M Caracciolo F Zippi M Pica R | 2006 | Helicobacter2006,11,: | 1 |
| 13 | Non-redundant successive approximation register for A/D converters显示文摘 | ROSSI A FUCILI G | 1996 | Electronics Letters1996,32,12: | 1 |
| 14 | Vascula rabnormalities and dere gulation of VEGF in Lkb1-deficient mice显示文摘 | Rossi DJ Korsisaari N | 2001 | Science2001,293,5533: | 1 |
| 15 | Lessons from the ( ' Iressa' expanded access programme: Gefitinib in special non-small-cell lung cancer patient populations 显示文摘 | Stahel R Rossi A Petruzelka L Kosimidis P de Braud F Bernardo MM | 2003 | Br J Cancer2003,89,2: | 1 |
| 16 | Imaging of acute disseminated encephalomyelitis 显示文摘 | Rossi A | 2008 | Neuroimag Clin N Am2008,18,1: | 1 |
| 17 | Critical temperatures for xylogenesis in conifers of cold climates显示文摘 | Rossi S Deslauries A Gricar J | 2008 | Glob Ecol Biogeogr2008,17,6: | 1 |
| 18 | Pulmonary carcinomas withpleomorphic,sarcomatoid,or sarcomatous elements:a clinicopathologic and immunohistochemical study of 75 cases显示文摘 | Rossi G Cavazza A Sturm N | 2003 | Am J SurgPathol2003,27,3: | 1 |
| 19 | Colorimetry of total phenols with phos-phomolybdic phosphotungstic acid reagets显示文摘 | SIGLETON V L ROSSI J A | 1965 | American Journal ofEnology and Viticulture1965,16,: | 1 |
| 20 | Doubly fed induction machines diagnosis based on signature analysis of rotor modulating signals显示文摘 | STEFANI A YAZIDI A ROSSI C | 2008 | IEEE Transactions on Industry App- lications2008,44,6: | 1 |