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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | 树轮记录的自公元1200年以来强火山喷发事件与高亚洲南部河流源区气候水文变化的关联显示文摘强火山喷发作为气候变化重要的外强迫因素,其所造成的气候环境效应一直是气候变化研究热点,而其对于流域水循环影响较少受关注。本文利用采自高亚洲南部河流源区麦吊云杉(Picea brachytyla)树轮样本,研制出一个长达885 a的树木年轮标准宽度年表。基于树轮气候响应分析结果,利用线性回归模型重建研究区自公元1200年上年11月至当年2月平均最低气温变化,重建方程方差解释量47.1%。该气温重建序列显示,研究区自公元1200年经历了8个冷期和9个暖期,包含有10个极冷年和23个极暖年。同时,该气温重建序列验证了自公元1200年来27次强火山喷发(VEI≥5)对于青藏高原东南部河流源区气候的影响,包括1257年Samalas和1815年Tambora等强火山喷发事件。该气温重建序列与相关河流径流数据对比结果表明强火山喷发在引起高亚洲南部河流源区气温出现明显下降的同时,也可能会进一步导致水循环减缓,使得高亚洲南部河流径流量出现减少。 | 陈友平 陈峰 张合理 胡茂 王世杰 Hadad Martín ARIEL Roig Junent Fidel ALEJANDRO | 2021 | 第四纪研究2021，41，2： | 12 |
| 3 | A Secure Elliptic Curve-Based RFID Protocol显示文摘Nowadays, the use of Radio Frequency Identification (RFID) systems in industry and stores has increased. Nevertheless, some of these systems present privacy problems that may discourage potential users. Hence, high confidence and efficient privacy protocols are urgently needed. Previous studies in the literature proposed schemes that are proven to be secure, but they have scalability problems. A feasible and scalable protocol to guarantee privacy is presented in this paper. The proposed protocol uses elliptic curve cryptography combined with a zero knowledge-based authentication scheme. An analysis to prove the system secure, and even forward secure is also provided. | Santi Martínez Magda Valls Concepció Roig Josep M. Miret Francesc Giné | 2009 | Journal of Computer Science & Technology2009，24，2： | 3 |
| 4 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 5 | Enteral glutamine supplementation for very low birth weight infants decreases morbidity显示文摘 | Roig JC Meetze WH Auesrad N | 1996 | J Nutr1996，126，4： | 1 |
| 6 | Magnetic Properties of γ-Fe2O3 Nanoparticles Obtained by Vaporization Condensation in a Solar Furnace显示文摘 | Martinez B Roig A Obradors X | 1996 | J Appl Phys1996，79，： | 1 |
| 7 | Enteral Glutamine supplementation for very low birth Weight infants decrease morbidny显示文摘 | Neu J Roig JC Meetze WH | 1997 | J Pediatr1997，131，5： | 1 |
| 8 | Changes in anorectal morphologic and functional parameters after fistula-in-ano surgery显示文摘 | Roig JV Jordan J Garcia-Armengol J | | 0，，08： | 1 |
| 9 | Biochar and denitrification in soils:When,how much and why does biochar reduce N2O emissions 显示文摘 | Cayuela M L Sanchez-Monedero M A Roig A | 2013 | Scientific Reports2013，3，： | 1 |
| 10 | J Electrochim Acta显示文摘 | ROIG A NAVARRO J GARCIA J J | 1994 | 39: 437-4401994，39，： | 1 |
| 11 | 显示文摘 | Molins E Roig A | 2000 | IEEE Trans Magn2000，36，： | 1 |
| 12 | Enhanced recovely in color-ectal surgery:a multicentre study显示文摘 | Ramifrez JM Blasco JV Roig JV | 2011 | BMC Surg2011，11，1： | 1 |
| 13 | Heavy metal bioavail- ability in a soil affected by mineral sulphides contamination following the mine spillage at Aznalcollar (Spain)显示文摘 | Clemente R Walker D J Roig A | 2003 | Biodegradation2003，14，3： | 1 |
| 14 | Nerccl,a mammalian NIMA-family kinase,binds the Ran GTPase and regulates mitotie progression显示文摘 | Roig J Mikhailov A Belham C | 2002 | Genes Dev2002，16，13： | 1 |
| 15 | Petri net analysis using Boolean manipulation in Proc Appl 显示文摘 | Pastor E Roig O Cortadella J | 1994 | Theory Petri Nets1994，，1： | 1 |
| 16 | Reduction of the enniatins A, A 1 , B, B 1 by an in vitro degradation employing different strains of probiotic bacteria: Identification of degradation products by LC–MS–LIT显示文摘 | M. Roig G. Meca E. Ferrer J. Ma?es | 2013 | Toxicon2013，，： | 1 |
| 17 | The learning curve in ambulatory laparoseopic cholecystectomy显示文摘 | Serra AS Roig MP Lledo J B | 2002 | Surg Laparose Endose Percutan Tech2002，12，5： | 1 |
| 18 | Nitrogen transformation during organic waste composting by the Rutgers system and its effects on pH,EC and maturity of the composting mixtures显示文摘 | SANCHEZ-MONEDERO M A ROIG A PAREDES C | 2001 | Bioresource Technology2001，78，3： | 1 |
| 19 | Active Nerccl protein kinase concentrates at centrosomes early in mitosis and is necessary for proper spindle assembly显示文摘 | Roig J Groen A Caldwell J | 2005 | Mol Cell Biol2005，16，48： | 1 |
| 20 | Pharmacogenomics strate- gies for developing customized chemotherapy in non-small cell lung cancer 显示文摘 | Sarries C Haura EB Roig B | 2002 | Pharmacogenomics2002，3，6： | 1 |
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