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1A totally mini-invasive approach for colorectal laparoscopic surgery显示文摘AIM:To study the short-term outcome of patients treated with laparoscopic right colectomy and how intracorporeal anastomosis has improved the outcome.METHODS:We retrospectively examined all patients affected by colorectal cancer who underwent a laparoscopic right colectomy between January 2006 and December 2010 in our department.Our evaluation criteria were:diagnosis of colorectal carcinoma at presurgical biopsy,elective surgery,and the same surgeon.We excluded:emergency surgery,conversions from laparotomic colectomy,and other surgeons.The endpoints we examined were:surgical time,number of lymph nodes removed,length of stay(removal of nasogastric tube,bowel movements,gas evacuation,solid and liquid feeding,hospitalization),and major complications.Seventy-two patients were divided into two groups:intracorporeal anastomosis(39 patients)and extracorporeal anastomosis(33 patients).RESULTS:Significant differences were observed between intracorporeal vs extracorporeal anastomosis,respectively,for surgical times(186.8 min vs 184.1 min,P < 0.001),time to resumption of gas evacuation(3 d vs 3.5 d,P < 0.001),days until resumption of bowel movements(3.8 d vs 4.9 d,P < 0.001),days until resumption of liquid diet(3.5 d vs 4.5 d,P < 0.001),days until resuming a solid diet(4.6 d vs 5.7 d,P < 0.001),and total hospitalization duration(7.4 d vs 8.5 d,P < 0.001).In the intracorporeal group,on average,19 positive lymph nodes were removed;in the extracorporeal group,on average,14 were removed P < 0.001).Thus,intracorporeal anastomosis for right laparoscopic colectomy improved patient outcome by providing faster recovery of nutrition,faster recovery of intestinal function,and shorter hospitalization than extracorporeal anastomosis.CONCLUSION:Short-term outcomes favor intracorporeal anastomosis,confirming that a less traumatic surgical approach improves patient outcome.Gabriele Anania Mirco Santini Lucia Scagliarini Alice Marzetti Laura Vedana Serafino Marino Claudio Gregorio Giuseppe Resta Giorgio Cavallesco 2012World Journal of Gastroenterology2012,18,29:8
2Doege-Potter syndrome by malignant solitary fibrous tumor of the liver: A case report and review of literature显示文摘BACKGROUND Solitary fibrous tumor of the liver (SFTL) is a rare occurrence with a low number of cases reported in literature. SFTL is usually benign but, 10%-20% cases are reported to be malignant with a tendency to metastasize. The majority of malignant SFTL cases are associated with a paraneoplastic hypoglycaemia defined as Doege-Potter syndrome. Surgery is the best therapeutic treatment, however, long- life follow-up is recommended. CASE SUMMARY A 74-year-old man, was admitted to the emergency department after a syncopal episode with detection of hypoglycaemia resistant to medical treatment. The computed tomography revealed a solid mass measuring 15 cm of the left liver. An open left hepatectomy was performed with complete resection of tumor. Histopathological analyses confirmed a malignant SFTL. CONCLUSION Large series with long-term follow-up have not been published neither have clinical trials been undertaken. Consequently, the methodical long-term followup of surgically treated SFTLs is strongly recommended.Delvecchio Antonella Duda Loren Conticchio Maria Fiore Felicia Lafranceschina Stefano Riccelli Umberto Cristofano Antonella Pascazio Bianca Colagrande Anna Resta Leonardo Memeo Riccardo 2019World Journal of Gastrointestinal Surgery2019,11,8:5
3The quasiparticle band dispersion in epitaxial multilayer silicene显示文摘Paola De Padova Jose Avila Andrea Resta Ivy Razado-Colambo Claudio Quaresima Carlo Ottaviani Bruno Olivieri Thomas Bruhn Patrick Vogt Maria Carmen Asensio Guy Le Lay 2013Journal of Physics: Condensed Matter2013,,:4
4Nonsense variant of ATP8B1 gene in heterozygosis and benign recurrent intrahepatic cholestasis: A case report and review of literature显示文摘BACKGROUND Benign recurrent intrahepatic cholestasis is a genetic disorder with recurrent cholestatic jaundice due to ATP8B1 and ABCB11 gene mutations encoding for hepato-canalicular transporters.Herein,we firstly provide the evidence that a nonsense variant of ATP8B1 gene(c.1558A>T)in heterozygous form is involved in BRIC pathogenesis.CASE SUMMARY A 29-year-old male showed severe jaundice and laboratory tests consistent with intrahepatic cholestasis despite normal gamma-glutamyltranspeptidase.Acute and chronic liver diseases with viral,metabolic and autoimmune etiology were excluded.Normal intra/extra-hepatic bile ducts were demonstrated by magnetic resonance.Liver biopsy showed:Cholestasis in the centrilobular and intermediate zones with bile plugs and intra-hepatocyte pigment,Kupffer’s cell activation/hyperplasia and preserved biliary ducts.Being satisfied benign recurrent intrahepatic cholestasis diagnostic criteria,ATP8B1 and ABCB11 gene analysis was performed.Surprisingly,we found a novel nonsense variant of ATP8B1 gene(c.1558A>T)in heterozygosis.The variant was confirmed by Sanger sequencing following a standard protocol and tested for familial segregation,showing a maternal inheritance.Immunohistochemistry confirmed a significant reduction of mutated gene related protein(familial intrahepatic cholestasis 1).The patient was treated with ursodeoxycholic acid 15 mg/kg per day and colestyramine 8 g daily with total bilirubin decrease and normalization at the 6th and 12th mo.CONCLUSION A genetic abnormality,different from those already known,could be involved in familial intrahepatic cholestatic disorders and/or pro-cholestatic genetic predisposition,thus encouraging further mutation detection in this field.Mariano Piazzolla Nicola Castellaneta Antonio Novelli Emanuele Agolini Dario Cocciadiferro Leonardo Resta Loren Duda Michele Barone Enzo Ierardi Alfredo Di Leo 2020World Journal of Hepatology2020,12,2:3
5Probiotics and Commensals Reverse TNF-α– and IFN-γ–Induced Dysfunction in Human Intestinal Epithelial Cells显示文摘Silvia Resta–Lenert Kim E. Barrett 2006Gastroenterology2006,,3:2
6Current scenario of the genetic testing for rare neurological disorders exploiting next generation sequencing显示文摘Next generation sequencing is currently a cornerstone of genetic testing in routine diagnostics,allowing for the detection of sequence variants with so far unprecedented large scale,mainly in genetically heterogenous diseases,such as neurological disorders.It is a fast-moving field,where new wet enrichment protocols and bioinformatics tools are constantly being developed to overcome initial limitations.Despite the as yet undiscussed advantages,however,there are still some challenges in data analysis and the interpretation of variants.In this review,we address the current state of next generation sequencing diagnostic testing for inherited human disorders,particularly giving an overview of the available high-throughput sequencing approaches;including targeted,whole-exome and whole-genome sequencing;and discussing the main critical aspects of the bioinformatic process,from raw data analysis to molecular diagnosis.Chiara Di Resta Giovanni Battista Pipitone Paola Carrera Maurizio Ferrari 2021Neural Regeneration Research2021,16,3:2
7The Metallic Nature of Epitaxial Silicene Monolayers on Ag(111)显示文摘Neil W. Johnson Patrick Vogt Andrea Resta Paola De Padova Israel Perez David Muir Ernst Z. Kurmaev Guy Le Lay Alexander Moewes 2014Adv. Funct. Mater2014,,:2
8The number of spermatozoa collected with testicular sperm extraction is a novel predictor of intracytoplasmic sperm injection outcome in non-obstructive azoospermic patients显示文摘这研究的目的是决定在精子发生的监视器和 intracytoplasmic 精子注射(ICSI ) 的预言者之间的关系在有经历阴囊的精子抽取(TESE ) 的非妨碍的精子缺乏(NOA ) 的病人的结果。有 NOA 的 79 个病人(吝啬的年龄:43.6 卤 5 .2 年,其中各个让步了(97 000 卤 3 040 ) 有常规 TESE 的精子,在我们的分析被考虑。他们的搭挡(吝啬的年龄:35.8 卤 5 .1 年) 经历了 184 个 ICSI 周期的一个总数;632 个卵母细胞被收集, 221 个卵母细胞被注射, 141 个卵母细胞被使肥沃, 121 个胚胎被获得, 110 个胚胎被转移, 14 临床的怀孕被完成,仅仅一流产发生了。Multivariate 回归分析与下列可变价值显示了在使肥沃的卵母细胞,转移胚胎和临床的怀孕的百分比之间的关系:女搭挡的年龄,精子的数字收集的、阴囊的体积,男搭挡刺激荷尔蒙(FSH ) 的滤泡的层次,收集的卵母细胞的数字,注射的卵母细胞的数字和 ICSI 的数字骑车。一种重要反的关系在女搭挡的年龄或男搭挡的 FSH 层次和生物化学的怀孕之间被发现。一种重要直接关系在 ICSI 周期的数字之间出现了,卵母细胞的百分比使肥沃,转移,并且每阴囊的活体检视在精子的数字之间收集了的胚胎和生物化学的怀孕。精子的数字断然被连接到临床的怀孕的数字, ICSI 周期的数字的独立人士和卵母细胞的数字收集 / 注射。收集的精子的数字, FSH 水平和阴囊的体积是连接到 ICSI 成功的精子发生的监视器。Giorgio Cavallini Maria Cristina Magli Andor Crippa Silvia Resta Giovanni Vitali Anna Pia Ferraretti Luca Gianaroli 2011Asian Journal of Andrology2011,13,2:2
9Isolation and characterizationof the promoter of the human 5' - nucleotidase (CD73)2encoding gene显示文摘Hansen KR Resta R Webb CF 1995Gene1995,167,12:1
10The specificity of ultrasound in the detection of fetal intracranial tumors显示文摘Vincenzo D’Addario Vincenzo Pinto Francesco Meo Maurizio Resta 2009Journal of Perinatal Medicine - Official Journal of the WAPM2009,,6:1
11A New Definition of Genetic Counseling: National Society of Genetic Counselors’ Task Force Report显示文摘Robert Resta Barbara Bowles Biesecker Robin L. Bennett Sandra Blum Susan Estabrooks Hahn Michelle N. Strecker Janet L. Williams 2006Journal of Genetic Counseling2006,,:1
12Ecto2enzyme and signaling functions of lymphocyte CD73显示文摘Resta R Yamashita Y Thompson LF 1998Immunol Rev1998,161,1:1
13Exhaled markers in the monitoring of airways inflammation and its response to steroid's treatment in mild persistent asthma显示文摘Carpagnano GE Foschino BMP Resta O 2005Eur J Pharmacol2005,519,12:1
14The Node Distribution of the Random Waypoint Mobility Model for Wireless Ad Hoc Networks显示文摘Bettstetter C Resta G Santi P 0,,03:1
15Independent modal control for nonlinear flexible structures : an experimental test rig 显示文摘Resta F Ripamonti F Cazzulani G 2010Journal of Sound and Vibration2010,329,8:1
16Endothelin-1 is increased in the breath condensate of patients with non-small-cell lung cancer显示文摘Carpagnano GE Foschino-Barbaro MP Resta O 2004Oncology2004,66,3:1
17Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia显示文摘 Talpaz M Resta D 2001N Engl J Med2001,344,:1
18Endothelin-1 is increased in breath condensate of patients with non-small cell lung cancer 显示文摘Carpagnano GE Fosehino Barbaro MP Resta O 2004Oncology2004,66,:1
19High speed railway:collecting pantographs active control and overhead lines diagnostic solution显示文摘Diana G Fossati F Resta F 1998Vehicle System Dynamics1998,30,:1
20Prenatal sonographic findings of trisomy 18 : review of 47 cases 显示文摘Nyberg DA Kramer D Resta R 1993J Ultrasound Med1993,2,:1
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