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| 1 | Modern management of rectal cancer: A 2006 update显示文摘The goal of this review is to outline some of the important surgical issues surrounding the management of patients with early (T1/T2 and NO), as well as locally advanced (T3/T4 and/or N1) rectal cancer. Surgery for rectal cancer continues to develop towards the ultimate goals of improved local control and overall survival, maintaining quality of life, and preserving sphincter, genitourinary, and sexual function. Information concerning the depth of tumor penetration through the rectal wall, lymph node involvement, and presence of distant metastatic disease is of crucial importance when planning a curative rectal cancer resection. Preoperative staging is used to determine the indication for neoadjuvant therapy as well as the indication for local excision versus radical cancer resection. Local excision is likely to be curative in most patients with a primary tumor which is limited to the submucosa (T1N0M0), without high-risk features and in the absence of metastatic disease. In appropriate patients, minimally invasive procedures, such as local excision, TEM, and laparoscopic resection allow for improved patient comfort, shorter hospital stays, and earlier return to preoperative activity level. Once the tumor invades the muscularis propria (T2), radical rectal resection in acceptable operative candidates is recommended. In patients with transmural and/or node positive disease (T3/T4 and/or N1) with no distant metastases, preoperative chemoradiation followed by radical resection according to the principles of TME has become widely accepted. During the planning and conduct of a radical operation for a locally advanced rectal cancer, a number of surgical management issues are considered, including: (1) total mesorectal excision (TME); (2) autonomic nerve preservation (ANP); (3) circumferential resection margin (CRM); (4) distal resection margin; (5) sphincter preservation and options for restoration of bowel continuity; (6) laparoscopic approaches; and (7) postoperative quality of life. | Glen C Balch Alex De Meo Jose G Guillem | 2006 | World Journal of Gastroenterology2006，12，20： | 26 |
| 2 | Quaternary high-resolution opal record and its paleoproductivity implication at ODP Site 1143,southern South China Sea显示文摘The correlation of opal content and MAR with oxygen isotopic records of benthonic foraminifera at Site 1143, southern South China Sea indicates that, since about 900 ka, the increasing opal content and MAR during the interglacial periods is inferred to reflect the higher surface productivity, for the intensified summer monsoon during the interglacial periods would result in the enhanced upwelling and nutrient supply. Time-sequence spectral analyses of oxygen isotopic record, opal content and MAR at intervals of 0900 ka reveal that the changes of surface productivity were dominantly forced by the variations of the earth orbital cycles. | WANG Rujian & LI Jian Laboratory of Marine Geology, MEO, Tongji University, Shanghai 200092, China | 2003 | Chinese Science Bulletin2003，48，4： | 17 |
| 3 | COVID-19疫苗:Pfizer/BioNTech和Moderna疫苗生物学、药理学特性和不良反应的比较显示文摘2019-nCoV所致的COVID-19已在世界范围内引起一场具有挑战性和威胁性的大流行,给人类健康和经济造成了巨大损失。美国食品和药品监督管理局(Food and Drug Administration,FDA)已经批准Pfizer/BioNTech和Moderna COVID-19疫苗的紧急使用许可。许多人对特定的食物、药物或疫苗有明显的过敏史;因此,世界各国都对这两种疫苗极为关注。本文比较了这两种疫苗的药理学、适应症、禁忌症和不良反应。 | Meo SA Bukhari IA Akram J 吕新军(编译) | 2021 | 中华实验和临床病毒学杂志2021，35，3： | 8 |
| 4 | Polyphenols-gut microbiota interplay and brain neuromodulation显示文摘Increasing evidence suggests that food ingested polyphenols can have beneficial effects in neuronal protection acting against oxidative stress and inflammatory injury. Moreover, polyphenols have been reported to promote cognitive functions. Biotransformation of polyphenols is needed to obtain metabolites active in brain and it occurs through their processing by gut microbiota. Polyphenols metabolites could directly act as neurotransmitters crossing the blood-brain barrier or indirectly by modulating the cerebrovascular system. The microbiota-gut-brain axis is considered a neuroendocrine system that acts bidirectionally and plays an important role in stress responses. The metabolites produced by microbiota metabolism can modulate gut bacterial composition and brain biochemistry acting as neurotransmitters in the central nervous system. Gut microbiota composition can be influenced by dietary ingestion of natural bioactive molecules such as probiotics, prebiotics and polyphenol. Microbiota composition can be altered by dietary changes and gastrointestinal dysfunctions are observed in neurodegenerative diseases. In addition, several pieces of evidence support the idea that alterations in gut microbiota and enteric neuroimmune system could contribute to onset and progression of these age-related disorders. The impact of polyphenols on microbiota composition strengthens the idea that maintaining a healthy microbiome by modulating diet is essential for having a healthy brain across the lifespan. Moreover, it is emerging that they could be used as novel therapeutics to prevent brain from neurodegeneration. | Stefania Filosa Francesco Di Meo Stefania Crispi | 2018 | Neural Regeneration Research2018，13，12： | 5 |
| 5 | Transcriptional regulation of miR-224 upregulated in human HCCs by NFκB inflammatory pathways显示文摘 | Cecilia Scisciani Stefania Vossio Francesca Guerrieri Valeria Schinzari Rossana De Iaco Paolo D’Onorio de Meo Melchiorre Cervello Giuseppe Montalto Teresa Pollicino Giovanni Raimondo Massimo Levrero Natalia Pediconi | 2011 | Journal of Hepatology2011，，4： | 2 |
| 6 | Delamination modelling in a double cantilever beam显示文摘 | M. Meo E. Thieulot | 2005 | Composite Structures2005，，3： | 2 |
| 7 | Management of patients with melanoma and non-melanoma skin cancers in the coronavirus disease 2019 era显示文摘The recent coronavirus disease 2019(COVID-19)pandemic has completely disrupted hospital and outpatient activities.[1,2]It has been reorganized to allow a lower inflow of patients,to reduce non-urgent out-patient visits and to concentrate public health forces in the fight against the COVID-19 outbreak.In this reorganization,dermatology departments have also adapted their activities suspending routine patient visits and providing only urgent surgical removal,urgent visits,consultations,and oncological examinations. | Claudio Conforti Nicola di Meo Roberta Giuffrida Iris Zalaudek | 2020 | Chinese Medical Journal2020，，17： | 2 |
| 8 | A critical analysis of the anterior - posterior radiographic anatomy of the ankle syndesmosis 显示文摘 | Ostrum RF Meo PD Subramanian R | 1995 | Foot Ankle lnt1995，16，： | 1 |
| 9 | The response of honey- comb sandwich panels under low-velocity impact loading 显示文摘 | Meo M Vignjevic R Marengo G | 2005 | Int J Mechan Sci2005，47，9： | 1 |
| 10 | Nonlinear Elastic Wave Spec- troscopy Identification of Impact Damage on a Sand- wich Plate显示文摘 | Meo M Zumpano G | 2005 | Composite Structures2005，71，3： | 1 |
| 11 | The specificity of ultrasound in the detection of fetal intracranial tumors显示文摘 | Vincenzo D’Addario Vincenzo Pinto Francesco Meo Maurizio Resta | 2009 | Journal of Perinatal Medicine - Official Journal of the WAPM2009，，6： | 1 |
| 12 | Amphotericin B suscep tibility testing of Candida lusitaniae isolates by flow cytoflu orometry: comparison with the Etest and the NCCLS broth maerodilution显示文摘 | Favel A Peyron F De Meo M | 1999 | J Antimicrob Chemother1999，43，2： | 1 |
| 13 | The prognostic value of vascular endothelial growth factor,urokinase plasminogen activator and plasmino gen activator inhibitor-1 in node-negative breast cancer显示文摘 | Meo S Dittadi R Pelosol L | 2004 | Int J Biol Markers2004，19，4： | 1 |
| 14 | Amphotericin B susceptibility testing of Candida lusitaniae isol-ates by flow cytofluorometry:comparison with the Etest and the NCCLS broth macrodilution method显示文摘 | Favel A Peyron F Meo DA | 1999 | J Antimicrob Chemother1999，43，2： | 1 |
| 15 | Effect of thyroid state on H2O2 production by mt liver mitochondria 显示文摘 | Venditti P De Rosa R Di Meo S | 2003 | Mol Cell Endocrinol2003，205，12： | 1 |
| 16 | Recommendation of similar users, resources and social networks in a social internetworking scenario 显示文摘 | Meo P D Nocera A | 2011 | Information Sciences2011，181，7： | 1 |
| 17 | Uterine pathologies in pa- tients undergoing tamoxifen therapy for breast cancer:ultrasonograph- ie, hysteroscopic and histological findings 显示文摘 | Le Donne M Lentini M De Meo L | 2005 | Eur J Gynaecol On- col2005，26，： | 1 |
| 18 | Carbon nanotubes:synthesis, proper- ties, and applications显示文摘 | MEO S B ANDREWS R | 2006 | Crit Rev Solid State Mater Sci2006，26，3： | 1 |
| 19 | The Genotoxicity of Acrylamide and Glycidamide in Big Blue Rats 显示文摘 | Meo N McDaniel LP Dobrovolsky VN | 2010 | Toxieol Sci2010，115，2： | 1 |
| 20 | Arthroscopic treatment of lateral meniscal cysts using an outside-in technique 显示文摘 | Tudisco C Meo A Blasucci C | 2000 | Am J Sports Med2000，28，5： | 1 |
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