|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 正常组织并发症概率模型综述显示文摘通过分析肿瘤放疗及并发症随访数据,拟合正常组织并发症概率(NTCP)模型参数,并由此预测并发症发病率、优化放疗方案、揭示正常组织放射生物学特性,是肿瘤放射生物物理学近期的研究热点。综述相关文献中提出的6种NTCP模型,并讨论建模及对比模型预测能力的方法;然后介绍近年来提出的几种改进后的NTCP模型,以及几种新的并发症预测技术。从开展临床应用的角度,对NTCP模型的研究现状、存在的问题和发展趋势做概括和总结,就NTCP模型在个体化放疗中的应用等问题进行讨论和展望。 | 朱健 李宝生 舒华忠 白曈 尹勇 罗立民 DE CREVOISIER Renaud | 2014 | 中国生物医学工程学报2014，31，2： | 7 |
| 2 | Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16" monocyte population via the IL-10/STAT3 axis显示文摘 | Claire Lastrucci Alan Benard Luciana Balboa Karine Pingris Shanti Sourian Renaud Poincloux Talal A Saati Voahangy Rasolofo Pablo Gonzfilez-Montaner Sandra Inwentarz Eduardo Jose Morafia Ivanela Kondova Frank AW Verreck Maria del Carmen Sasiain Olivier Neyrolles Isabelle Maridonneau-Parini Geanncarlo Lugo-Villarino Ce1ine Cougoule | 2015 | Cell Research2015，25，12： | 7 |
| 3 | 肿瘤放疗并发症概率预测模型参数拟合方法显示文摘为了建立具有群体特异性的肿瘤放疗NTCP预测模型,提出了一种模型参数拟合方法.首先,基于NTCP模型的特点构建最大似然函数;然后,分别采用确定性优化方法和随机性优化方法对最大似然函数进行优化,分析优化过程的时间成本及优化结果,探讨用于拟合NTCP模型参数的最优方法.实验结果表明,用于拟合NTCP模型参数的最大似然函数是非凸的,存在局部最优解;遗传算法是一种最稳定的最大似然函数优化方法,其运行时间比模拟退火算法短,而且可以在每次优化结束后给出全局最优解,以作为NTCP模型参数.所提方法可以帮助肿瘤放疗工作者在临床随访数据的基础上建立具有群体特异性的放疗并发症预测模型. | 朱健 白曈 李宝生 舒华忠 Antoine Simon Renaud de Crevoisier | 2015 | 东南大学学报(自然科学版)2015，45，2： | 4 |
| 4 | 小P值并不能保证可靠结果:以帕金森病的静息态脑功能成像元分析为例显示文摘Thousands of resting state functional magnetic resonance imaging(RS-f MRI)articles have been published on brain disorders.For precise localization of abnormal brain activity,a voxel-level comparison is needed.Because of the large number of voxels in the brain,multiple comparison correction(MCC)must be performed to reduce false positive rates,and a smaller P value(usually including either liberal or stringent MCC)is widely recommended[1]. | 贾熙泽 赵娜 董昊铭 孙家伟 Marek Barton Roxana Burciu Nicolas Carrière Antonio Cerasa 陈博宇 陈俊 Stephen Coombes Luc Defebvre Christine Delmaire Kathy Dujardin Fabrizio Esposito 范国光 Federica Di Nardo 冯怡萱 Brett W.Fling Saurabh Garg Moran Gilat Martin Gorges Shu-Leong Ho Fay B.Horak 胡晓 胡晓飞 黄飚 黄沛钰 贾泽娟 Christina Jones Jan Kassubek Lenka Krajcovicova Ajay Kurani 李静 李晴 刘爱萍 刘波 刘虎 刘卫国 Renaud Lopes 娄毓婷 罗巍 Tara Madhyastha 毛妮妮 Grainne McAlonan Martin J.McKeown Shirley Pang Andrea Quattrone Irena Rektorova Alessia Sarica 商慧芳 James M.Shine Priyank Shukla Tomas Slavicek 宋潇鹏 Gioacchino Tedeschi Alessandro Tessitore David Vaillancourt 王健 王珏 Z.Jane Wang 魏鲁庆 邬霞 徐晓俊 闫磊 杨靓 杨万群 姚乃琳 张得龙 张久权 张敏鸣 张艳玲 周彩红 严超赣 左西年 Mark Hallett 吴涛 臧玉峰 | 2021 | Science Bulletin2021，66，21： | 3 |
| 5 | Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors显示文摘Factors released by surrounding cells such as cancer-associated mesenchymal stromal cells(CA-MSCs)are involved in tumor progression and chemoresistance.In this study,we characterize the mechanisms by which naYve mesenchymal stromal cells(MSCs)can acquire a CA-MSCs phenotype.Ovarian tumor cells trigger the transformation of MSCs to CA-MSCs by expressing pro-tumoral genes implicated in the chemoresistance of cancer cells,resulting in the secretion of high levels of CXC chemokine receptors 1 and 2(CXCR1/2)ligands such as chemokine(C-X-C motif)ligand 1(CXCL1),CXCL2,and interleukin 8(IL-8).CXCR1/2 ligands can also inhibit the immune response against ovarian tumor cells.Indeed,through their released factors,CA-MSCs promote the differentiation of monocytes towards M2 macrophages,which favors tumor progression.When CXCR1/2 receptors are inhibited,these CA-MSC-activated macrophages lose their M2 properties and acquire an anti-tumoral phenotype.Both ex vivo and in vivo,we used a CXCR1/2 inhibitor to sensitize ovarian tumor cells to carboplatin and circumvent the pro-tumoral effects of CA-MSCs.Since high concentrations of CXCR1/2 ligands in patients*blood are associated with chemoresistance,CXCR1/2 inhibition could be a potential therapeutic strategy to revert carboplatin resistance. | Augustin Le Naour Melissa Prat Benolt Thibault Renaud Mével Léa Lemaitre Helene Leray Marie-Veronique Joubert Kimberley Coulson Muriel Golzio Lise Lefevre Eliane Mery Alejandra Martinez Gwénael Ferron Jean-Pierre Delord Agnès Coste Bettina Couderc | 2020 | Journal of Molecular Cell Biology2020，12，3： | 3 |
| 6 | 光纤聚合物探针在非均匀电磁场下的银纳米颗粒极化效应显示文摘介绍了光纤探针的制作流程及纳米颗粒的吸附方法,利用时域有限差分法对光纤探针的局域非均匀场下银纳米颗粒增强效应进行了数值模拟。首先,分析了不同形状的光纤聚合物探针尖端电场分布情况,为纳米颗粒的极化效应研究提供了参考;其次,模拟与仿真了纳米颗粒的半径、与探针间的距离对单个银纳米颗粒极化效应的影响;最后,以两个银纳米颗粒为例讨论了颗粒相对位置对极化效果的影响,并证明了光纤探针顶端以外的银纳米颗粒对电场的极化效应没有贡献。本文的仿真结果为光纤探针的制备以及其表面银纳米颗粒的吸附提供了理论支持。 | 郑守国 李淼 张健 曾新华 Jerome Plain Renaud Bachelot 乔雷 | 2013 | 发光学报2013，34，5： | 2 |
| 7 | Toxoplasmosis among pregnant women:High seroprevalence and risk factors in Kinshasa,Democratic Republic of Congo显示文摘Objective:To determine the seroprevalence of toxoplasmosis in pregnant women,as well as the proportion of acutely infected and risk factors in the Democratic Republic of Congo.Methods:Thirty maternities in Kinshasa were randomly selected and women attending antenatal consultation were invited to participate.They were interviewed with a structured questionnaire about known risk factors(age,meat consumption,contact with soil,and presence of cat)and a venous blood sample was taken.Sera were analysed for total immunoglobulins(Ig)by VIDAS Toxo Competition using Enzyme Linked Fluorescent Assay.IgM was determined by VIDIA Toxo IgM and IgG avidity by VIDAS Toxo IgG avidity.Results:A total of 781 women were included.Median age was 28 years old(IQR:8.S).And 627women(80.3%;95%CI:77.5-83.1)were found to be positive to total Ig and 17 out of 387(4.4%;95%CI:2.3-6.4)were positive to IgM.IgC avidity was low for 2(11.8%)women,intermediate for 2(11.8%)and high for 13 women(76.4%).There was no statistically significant association between Toxoplasma gondii infection and any risk factors assessed.Conclusion:In Kinshasa,toxoplasmosis endemicity is highly prevalent.One woman out of twenty five had a recent toxoplasmosis infection and 20%were not protected against primoinfection,indicating a need for measures to prevent and control toxoplasmosis during pregnancy. | Doudou Yobi Renaud Piarroux Coralie L'Ollivier Jacqueline Franck Hypolite Situakibanza Hypolite Muhindo Patrick Mitashi Raquel Andreia Inocencio da Luz Marc Van Sprundel Marleen Boelaert Jean-Pierre Van Geertruyden Pascal Lutumba | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，1： | 2 |
| 8 | Continuous circuit coprecipitation of arsenic(V) with ferric iron by lime neutralization: Process parameter effects on arsenic removal and precipitate quality显示文摘 | Richard Jack De Klerk Yongfeng Jia Renaud Daenzer Mario A. Gomez George P. Demopoulos | 2011 | Hydrometallurgy2011，，： | 2 |
| 9 | 一种大变形多空间域连续体结构拓扑优化方法显示文摘针对大变形非线性结构拓扑优化问题,提出了基于混合细胞自动机(HCA,Hybrid CellularAutomata)多空间域连续体结构拓扑优化方法;采用密度法,建立了单元相对密度表示的材料弹-塑性模型;以单元相对密度和应变能作为细胞自动机(CA,Cellular Automata)的状态信息,利用CA局部控制规则,修改相对密度,迭代实现各设计空间域应变能均匀分布;设计了多空间域拓扑优化HCA算法,采取多个对象同时耦合优化迭代,各自收敛策略,解决了多空间域优化迭代算法收敛稳定性问题;最后,以汽车保险杆结构横梁和支撑等两个设计空间为例,施加大变形动态载荷作用,对提出的多空间结构优化算法进行了验证,优化后结构有效地降低了碰撞作用力峰值达54%,提高了结构安全性. | 郭连水 Punit Bandi John E. Renaud | 2009 | 北京航空航天大学学报2009，35，2： | 2 |
| 10 | Field synergy analysis of pollutant dispersion in street canyons and its optimization by adding wind catchers显示文摘The microenvironment,which involves pollutant dispersion of the urban street canyon,is critical to the health of pedestrians and residents.The objectives of this work are twofold:(i)to effectively assess the pollutant dispersion process based on a theory and(ii)to adopt an appropriate stratigy,i.e.,wind catcher,to alleviate the pollution in the street canyons.Pollutant dispersion in street canyons is essentially a convective mass transfer process.Because the convective heat transfer process and the mass transfer process are physically similar and the applicability of field synergy theory to turbulence has been verified in the literature,we apply the field synergy theory to the study of pollutant dispersion in street canyons.In this paper,a computational fluid dynamics(CFD)simulation is conducted to investigate the effects of wind catcher,wind speed and the geometry of the street canyons on pollutant dispersion.According to the field synergy theory,Sherwood number and field synergy number are used to quantitatively evaluate the wind catcher and wind speed on the diffusion of pollutants in asymmetric street canyons.The results show that adding wind catchers can significantly improve the air quality of the step-down street canyon and reduce the average pollutant concentrations in the street canyon by 75%.Higher wind speed enhances diffusion of pollutants differently in different geometric street canyons. | Tingzhen Ming Huina Han Zhen Zhao Renaud de Richter Yongjia Wu Wei Li Nyuk Hien Wong | 2021 | Building Simulation2021，14，2： | 2 |
| 11 | The vaginal radical trachelectomy: An update of a series of 125 cases and 106 pregnancies显示文摘 | Marie Plante Jean Gregoire Marie-Claude Renaud Michel Roy | 2010 | Gynecologic Oncology2010，，： | 2 |
| 12 | LiToTac: An Interactive-Interface Software for Finite Element Analysis of Multiple Contact Dynamics显示文摘In order to investigate the mechanical behavior of systems with complex architecture and a large number of contacting bodies,a finite element software,named LiToTac,has been developed by using the object-oriented programming technique.This software,with an interactive graphical user interface,is able to handle highly non-linear problems including multiple contacts and large deformation.More importantly,the contact detection based on a hybrid three-stages methodology can be performed automatically,which is more efficient than the common strategies of pre-defining contact zones in commercial FEM software like ANSYS,ABAQUS,etc.In addition,the contact solver in LiToTac is portable between dynamic and quasi-static codes and can accurately solve contact coupled with friction in a reduced system.Several numerical examples are carried out to illustrate the functionality and capacity of the software package. | Lei Peng Zhiqiang Feng Pierre Joli Christine Renaud | 2019 | Computer Modeling in Engineering & Sciences2019，，1： | 2 |
| 13 | Fast unfolding of communities in large networks显示文摘 | Vincent D Blondel Jean-Loup Guillaume Renaud Lambiotte Etienne Lefebvre | 2008 | Journal of Statistical Mechanics: Theory and Expe2008，，： | 2 |
| 14 | Design of a motorised plasma delivery system for ultra-precision large optical fabrication显示文摘A unique plasma figuring(PF)process was created and demonstrated at Cranfield University for manufacturing extremely large telescopes.The atmospheric pressure processing is faster and more cost-effective than other finishing processes;thus,providing an important alternative for large optical surfaces.The industrial scale manufacturing of thousands of ultra-precision metre-scale optics requires a robust PF machine:this requirement is achieved by making the plasma delivery system(PDS)performance repeatable.In this study,a dedicated PDS for large optical manufacturing was proposed to meet the industrial requirement.The PDS is based on an L-type radiofrequency(RF)network,a power supply,and an inductively coupled plasma torch.However,the complexities of these technologies require an in depth understanding of the integrated components that from the PDS.A smart control system for the modified PDS was created.This novel control system aims to make the characterization process deterministic:by automating the tuning of critical electrical components in the RF network,which is achieved by the use of in-line metrology.This paper describes the main design aspects.The PDS was tested with a good correlation between capacitance and RF frequencies.The robust PDS design enables a stable discharge of plasma with a low deviation of RF signals during the total15 hours’test. | Hui Zhou Adam Bennett Marco Castelli Renaud Jourdain Jiang Guo Nan Yu | 2020 | International Journal of Extreme Manufacturing2020，2，4： | 2 |
| 15 | Evaluation of recently isolated Australian tropical microalgae for the enrichment of the dietary value of brine shrimp, Artemia nauplii显示文摘 | Thinh Luong-Van Renaud S M Parry D L | 1999 | Aquaculture1999，170，： | 2 |
| 16 | The 1985 to 1994 Global Real Estate Cycle: An Overview显示文摘 | Bertrand Renaud | 1997 | Journal of Real Estate Literature1997，，： | 2 |
| 17 | Reliability-based design optimization of robotic system dynamic显示文摘 | BOWLING A P RENAUD J E NEWKIRK J T | 2007 | Journal of Mechanical Design2007，127，4： | 1 |
| 18 | Tamishing of AuAgCu alloys--Effect of the composition 显示文摘 | RAND1N J P RAMONI P RENAUD J P | 1992 | Materials and Corrosion1992，43，3： | 1 |
| 19 | A rapid and reliable method for metabolite extraction in yeast using boiling buffered ethanol 显示文摘 | Gonzalez B Francois J Renaud M | 1997 | Yeast1997，13，14： | 1 |
| 20 | Update strategies for Kriging models used in variable fidelity optimization显示文摘 | GANO S E RENAUD J E MARTIN J D | 2006 | Structural and Multidisciplinary Optimization2006，32，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员