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| 1 | Temporal increases in plasma markers of oxidized low - density lipoprotein strongly reflect the presence of acute coronary syndromes显示文摘 | Sotirios Tsimikas Claes B Reinaldo WB | 2003 | J Am Coll Cardiol2003，41，3： | 1 |
| 2 | Apolipoprotein E polymorphism influences orthotopic liver transplantation outcomes in patients with hepatitis C virus-induced liver cirrhosis显示文摘BACKGROUND Hepatitis C virus(HCV)infection is responsible for a chronic liver inflammation,which may cause end-stage liver disease and hepatocellular carcinoma.Apolipoprotein E(protein:ApoE,gene:APOE),a key player in cholesterol metabolism,is mainly synthesized in the liver and APOE polymorphisms may influence HCV-induced liver damage.AIM To determine whether APOE alleles affect outcomes in HCV-infected patients with liver cirrhosis following orthotopic liver transplantation(OLT).METHODS This was a cohort study in which 179 patients,both genders and aged 34-70 years,were included before or after(up to 10 years follow-up)OLT.Liver injury severity was assessed using different criteria,including METAVIR and models for endstage liver disease.APOE polymorphisms were analyzed by quantitative real-time polymerase chain reaction.RESULTS The APOE3 allele was the most common(67.3%).In inflammation severity of biopsies from 89 OLT explants and 2 patients in pre-transplant,the degree of severe inflammation(A3F4,0.0%)was significantly less frequent than in patients with minimal and moderate degree of inflammation(≤A2F4,16.2%)P=0.048,in patients carrying the APOE4 allele when compared to non-APOE4.In addition,a significant difference was also found(≤A2F4,64.4%vs A3F4,0.0%;P=0.043)and(A1F4,57.4%vs A3F4,0.0%;P=0.024)in APOE4 patients when compared to APOE3 carriers.The fibrosis degree of the liver graft in 8 of 91 patients and the lack of the E4 allele was associated with more moderate fibrosis(F2)(P=0.006).CONCLUSION Our results suggest that the E4 allele protects against progression of liver fibrosis and degree of inflammation in HCV-infected patients. | José Carlos Rodrigues Nascimento Lianna C Pereira Juliana Magalhães C Rêgo Ronaldo P Dias Paulo Goberlânio B Silva Silvio Alencar C Sobrinho Gustavo R Coelho Ivelise Regina C Brasil Edmilson F Oliveira-Filho James S Owen Pierluigi Toniutto Reinaldo B Oriá | 2021 | World Journal of Gastroenterology2021，27，11： | 1 |
| 3 | Water level dynamics in the Amazon flood plain显示文摘 | IVAN B T L REINALDO R R FERNANDO M R | 2003 | Advances in Water Resources2003，26，7： | 1 |
| 4 | Designing systems-on-chip using cores显示文摘 | Reinaldo A B William R L | 2000 | Annual ACM IEEE Design Automation Conference Proceedings of 37th conference on design automation2000，，： | 1 |
| 5 | Heuristically accelerated multi agent reinforcement learning显示文摘 | REINALDO A C B MARTINS M F RIBEIRO C H C | 2014 | IEEE Transactions on Cybernetics2014，44，2： | 1 |
| 6 | Computational evaluation of effective material properties of composites reinforced by randomly distributed spherical particles 显示文摘 | Sreedhar K Harald B Reinaldo R Ulrich G | 2007 | Composite Structures2007，77，2： | 1 |
| 7 | Bridging the domains of high-level and logic synthesis 显示文摘 | Reinaldo A B | 2002 | IEEE Computer-Aided Design of Integrated Circuits and Systems2002，21，5： | 1 |
| 8 | Bridging the domains of high-level and logic synthesis 显示文摘 | Reinaldo A B | 2002 | IEEE JCAD2002，21，5： | 1 |
| 9 | Hot-Film Mea- surements on a Low Pressure Turbine Linear Cascade with Bypass Transition 显示文摘 | Reinaldo A Gomes S S Franz B | 2015 | ASME Journal of Turboma- chinery2015，137，09： | 1 |
| 10 | Factors influencing algae-clay aggregation显示文摘 | MARIANA G REINALDO B | 2004 | Hydrobiologia2004，523，： | 1 |
| 11 | Alanyl -glutamine and glutamine supplementation improves 5-fluorouracil-induced intestinal epithelium damage in vitro显示文摘 | Braga-Neto Manuel B Warren Cirle A Oria Reinaldo B | 2008 | Dig Dis Sci2008，53，10： | 1 |
| 12 | Computational evaluation of effective material properties of composites reinforced by randomly distributed spherical particles显示文摘 | Sreedhar K Harald B Reinaldo R Ulrich G | | 0，，02： | 1 |
| 13 | Bridging the Domains of High-level and Logic Synthesis显示文摘 | Reinaldo A B | 2002 | IEEE Computer-aided Design of Integrated Circuits and Systems2002，21，5： | 1 |
| 14 | Extreme event dynamics in methane ebullition fluxes from tropical reservoirs 显示文摘 | Fernado M Ramas Ivan B T Lima Reinaldo R Rosa | 2006 | Geophysical Research Letters2006，33，21： | 1 |
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