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| 1 | Phosphate Starvation Responses and Gibberellic Acid Biosynthesis Are Regulated by the MYB62 Transcription Factor in Arabidopsis显示文摘在大多数土壤的磷酸盐(Pi ) 的有限可获得性在植物导致 Pi 饥饿回答的表明。把 Pi 压力反应机制的 transcriptional 规定,我们描绘了 MYB62 的生物角色,响应 Pi 被导致的一个 R2R3 类型 MYB 抄写因素缺乏。MYB62 的正式就职在 Pi 剥夺期间是在叶子的特定的回答。MYB62 蛋白质本地化到原子核。MYB62 的 overexpression 导致了改变的根建筑学, Pi 举起,和酸磷酸酶活动,导致在射击的减少的全部的 Pi 内容。几 Pi 的表示导致饥饿(希腊语的第二十三个字母) 基因也在 MYB62 overexpressing 植物被压制。MYB62 的 Overexpression 导致了能部分是的缺乏的显型由 GA 的外长的申请颠倒了的典型 gibberellic 酸(GA ) 。另外, SOC1 和超人的表示, flowering 的分子的管理者,在 MYB62 overexpressing 植物被压制。有趣地,这些基因的表示也在野类型的植物在 Pi 剥夺期间被减少,建议为在 Pi 饥饿回答的 GA biosynthetic 和花的规章的基因的一个角色。因此,这研究在 GA 新陈代谢经由变化在磷酸盐饥饿回答的规定加亮 MYB62 的角色并且发信号。在 Pi 动态平衡和 GA 之间的如此的串音可能在滋养的应力期间在 flowering,根发展和适应机制上有更宽广的含意。 | Ballachanda N. Devaiah Ramaiah Madhuvanthi Athikkattuvalasu S. Karthikeyan Kashchandra G. Raghothama | 2009 | Molecular Plant2009,2,1: | 62 |
| 2 | Pancreatic stellate cell: Pandora's box for pancreatic disease biology显示文摘Pancreatic stellate cells(PSCs) were identified in the early 1980 s, but received much attention after 1998 when the methods to isolate and culture them from murine and human sources were developed. PSCs contribute to a small proportion of all pancreatic cells under physiological condition, but are essential for maintaining the normal pancreatic architecture. Quiescent PSCs are characterized by the presence of vitamin A laden lipid droplets. Upon PSC activation, these perinuclear lipid droplets disappear from the cytosol, attain a myofibroblast like phenotype and expresses the activation marker, alpha smooth muscle actin. PSCs maintain their activated phenotype via an autocrine loop involving different cytokines and contribute to progressive fibrosis in chronic pancreatitis(CP) and pancreatic ductal adenocarcinoma(PDAC). Several pathways(e.g., JAK-STAT, Smad, Wnt signaling, Hedgehog etc.), transcription factors and mi RNAs have been implicated in the inflammatory and profibrogenic function of PSCs. The role of PSCs goes much beyond fibrosis/desmoplasia in PDAC. It is now shown that PSCs are involved in significant crosstalk between the pancreatic cancer cells and the cancer stroma. These interactions result in tumour progression, metastasis, tumour hypoxia, immune evasion and drug resistance. This is the rationale for therapeutic preclinical and clinical trials that have targeted PSCs and the cancer stroma. | Ratnakar R Bynigeri Aparna Jakkampudi Ramaiah Jangala Chivukula Subramanyam Mitnala Sasikala G Venkat Rao D Nageshwar Reddy Rupjyoti Talukdar | 2017 | World Journal of Gastroenterology2017,23,3: | 25 |
| 3 | SSJD14080400004873显示文摘 | Roberto Galuppo Dinesh Ramaiah Oscar Moreno Ponte Roberto Gedaly | 2014 | Digestive Diseases and Sciences2014,,8: | 2 |
| 4 | miR-15/16 complex targets p70S6 kinase1 and controls cell proliferation in MDA-MB-231 breast cancer cells显示文摘 | M. Janaki Ramaiah A. Lavanya Mohsen Honarpisheh Mojtaba Zarea Utpal Bhadra Manika Pal Bhadra | 2014 | Gene2014,,: | 2 |
| 5 | Use of a chiA probe for detection of chitinase genes in bacteria from the Chesapeake Bay 显示文摘 | RAMAIAH N HILL R T CHUN J | 2000 | Ferns Microbiol Ecol2000,34,1: | 1 |
| 6 | Endografting of the thoracic aorta显示文摘 | Ramaiah V Rodriguez-Lopez J Diethrich EB | 2003 | J Card Surg2003,18,: | 1 |
| 7 | Postoperative cognitive dysfunction in the eld-erly 显示文摘 | Ramaiah R Lam AM | 2009 | Anesthesiol Clin2009,27,3: | 1 |
| 8 | Intravascular ultrasound imaging as applied to the aorta:a new tool for the cardiovascular surgeon显示文摘 | Kpodonu J Ramaiah VG Diethrich EB | 2008 | Ann Thorac Surg2008,86,4: | 1 |
| 9 | Bacterial abun dance, communities and heterotrophic activities in the coastal waters of Tamil Nadu 显示文摘 | Ramaiah N Raghukumar C Sheelu G | 1996 | Indian Journal of Marine Sciences1996,25,3: | 1 |
| 10 | Marine environmental pollution stress detection throughdirect viable counts of bacteria显示文摘 | RAMAIAH N | 2002 | Water Research2002,36,: | 1 |
| 11 | Synthesis and biological evaluation of 415-sulphonamido and 4~- podophyllotoxins as DNA topoisomerase-IIct and apoptosis inducing agents 显示文摘 | KAMAL A SURESH P RAMAIAH M J | 2012 | Bioorg Med Chem2012,20,: | 1 |
| 12 | A novel bisindole-PBD conjugate causes DNA damage induced apoptosis via inhibition of DNA repair pathway显示文摘 | Sarma P Ramaiah M J Kamal A | 2014 | Cancer Biol Ther2014,15,10: | 1 |
| 13 | Marine environmental pollution stress detection throughdirect viable counts of bacteria 显示文摘 | RAMAIAH N | 2002 | Water Research2002,36,: | 1 |
| 14 | Reduced eIF2αphosphorylation and increased proapoptotic proteins in aging显示文摘 | Hussain SG Ramaiah KV | 2007 | Biochem Biophys Res Commun2007,355,2: | 1 |
| 15 | A novel approach for speaker diarization system using TMFCC parameterization and Lion optimization显示文摘In audio stream containing multiple speakers, speaker diarization aids in ascertaining 'who speak when'. This is an unsupervised task as there is no prior information about the speakers. It labels the speech signal conforming to the identity of the speaker, namely, input audio stream is partitioned into homogeneous segments. In this work, we present a novel speaker diarization system using the Tangent weighted Mel frequency cepstral coefficient(TMFCC) as the feature parameter and Lion algorithm for the clustering of the voice activity detected audio streams into particular speaker groups. Thus the two main tasks of the speaker indexing, i.e., speaker segmentation and speaker clustering, are improved. The TMFCC makes use of the low energy frame as well as the high energy frame with more effect, improving the performance of the proposed system. The experiments using the audio signal from the ELSDSR corpus datasets having three speakers, four speakers and five speakers are analyzed for the proposed system. The evaluation of the proposed speaker diarization system based on the tracking distance, tracking time as the evaluation metrics is done and the experimental results show that the speaker diarization system with the TMFCC parameterization and Lion based clustering is found to be superior over existing diarization systems with 95% tracking accuracy. | V.Subba Ramaiah R.Rajeswara Rao | 2017 | Journal of Central South University2017,24,11: | 1 |
| 16 | Profiling of a few immune re-sponsive genes expressed in postlarvae of Fenneropenaeus indicus chal-lenged with Vibrio harveyi D3显示文摘 | NAYAK S AJAY K M RAMAIAH N | 2011 | Journal of Invertebrate Pathology2011,107,: | 1 |
| 17 | Mechanisms of immune-mediated liver injury显示文摘 | Adams DH Ju C Ramaiah SK Uetrecht J Jaeschke H | 2010 | Toxicol Sci2010,115,2: | 1 |
| 18 | Aluminum Chloide Catalyzed Nitration of Aromatics with Sodium Nitrate/Chorotrimethylsilane显示文摘 | Ramaiah P Sandford G | 1994 | Synthesis1994,,: | 1 |
| 19 | Identification of upregulatedimmune-related genes in Vibrio harveyi challenged Penaeus monodon post-larvae显示文摘 | NAYAK S SINGH S K RAMAIAH N | 2010 | Fish&Shellfish Immunology2010,29,: | 1 |
| 20 | Endoluminal stent-graft stabilization for thoracic aortic dissection显示文摘 | Nathanson DR Rodriguez-lopez JA Ramaiah VG | 2005 | J Endovasc Ther2005,12,3: | 1 |