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| 1 | Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo显示文摘The hepatic sinusoids are lined by a unique population of hepatic sinusoidal endothelial cells (HSEC), which is one of the first hepatic cell populations to come into contact with blood components. However, HSEC are not simply barrier cells that restrict the access of blood- borne compounds to the parenchyma. They are func- tionally specialised endothelial cells that have complex roles, including not only receptor-mediated clearance of endotoxin, bacteria and other compounds, but also the regulation of inflammation, leukocyte recruitment and host immune responses to pathogens. Thus understand- ing the differentiation and function of HSEC is critical for the elucidation of liver biology and pathophysiology. This article reviews methods for isolating and studying human hepatic endothelial cell populations using in vitro models. We also discuss the expression and functions of phe- notypic markers, such as the presence of fenestrations and expression of VAP-1, Stabilin-1, L-SIGN, which can be used to identify sinusoidal endothelium and to permit discrimination from vascular and lymphatic endothelial cells. | PF Lalor SM Curbishley S Shetty DH Adams | 2006 | World Journal of Gastroenterology2006，12，34： | 11 |
| 2 | Surgical treatment of the ischemic mitral valve显示文摘 | Adams DH Filsoufi F Aklog L | 2002 | J Heart Valve Dis2002，，： | 1 |
| 3 | Techniques and results of direct - access minimally invasive mitral valve surgery ~ a paradigm for the future显示文摘 | Aklog L Adams DH Couper GS | 1998 | J Thorac Cardiovasc1998，116，5： | 1 |
| 4 | The role of chemokines in the recruitment of lymphocytes to the liver 显示文摘 | Oo YH Adams DH | 2010 | J Autoimmun2010，34，1： | 1 |
| 5 | Serum hyaluronic acid following liver transplantation : evidence of hepatic endothelial damage 显示文摘 | Adams DH Wang L Neuberger JM | 1989 | Transplant Proceedings1989，21，1： | 1 |
| 6 | The role of chemokines in the re-cruitment of lymphocytes to the liver显示文摘 | Oo YH Shetty S Adams DH | 2010 | Dig Dis2010，28，1： | 1 |
| 7 | Technique and resuhs of direct-access minimally invasive mitral valve surgery:a paradigm for the future显示文摘 | Aklog L Adams DH Couper GS | | 0，，05： | 1 |
| 8 | Novel therapeutic targets in primary biliary cirrhosis显示文摘 | Dyson JK Hirschfield GM Adams DH | 2015 | Nat Rev Gastroenterol Hepatol2015，12，3： | 1 |
| 9 | PrediBtors of atrrial fibrillation after Boronary surgery显示文摘 | Aranki SF Shaw DP Adams DH | 1996 | BirBulation1996，94，： | 1 |
| 10 | Management of patients with difficult autoimmune hepatitis 显示文摘 | Parker R Oo YH Adams DH | 2012 | Therap Adv Gastroenterol2012，5，6： | 1 |
| 11 | Population comparison of two clinical approaches to the metabolic syndrome implication of the new International Diabetes Federation consensus definition 显示文摘 | Adams R J Appreton S Wilson DH | 2005 | Diabetes Care2005，28，11： | 1 |
| 12 | Psychological factors and asthma quality of Life:a population based study显示文摘 | Adams RJ Wilson DH Taylor AW | | 0，，： | 1 |
| 13 | Immunology of the gut and liver:a love/hate relationship 显示文摘 | ADAMS DH EKSTEEN B CURBISHLEY SM | 2008 | Gut2008，57，： | 1 |
| 14 | The role of chemokines in the recruitment of lymphocytes to the liver 显示文摘 | Oo YH Adams DH | 2010 | J Autoimmun2010，34，1： | 1 |
| 15 | Mechanisms of immune-mediated liver injury显示文摘 | Adams DH Ju C Ramaiah SK Uetrecht J Jaeschke H | 2010 | Toxicol Sci2010，115，2： | 1 |
| 16 | Autoimmune Hepatitis:new paradigms in the pathogenesis,disgnosis and management显示文摘 | Oo YH Hubscher SG Adams DH | 2010 | Hepatol Int2010，4，2： | 1 |
| 17 | Generation of marker-free transgenic maize by regular two border Agrobacterium transformation vectors显示文摘 | Huang S Gilbertson LA Adams TH Malloy KP Reisenbigler EK Birr DH Snyder MW Zhang Q Luethry MH | | 0，，： | 1 |
| 18 | Expression of E-selectin and E-selectin ligands in human liver inflammation 显示文摘 | ADAMS DH HUBSCHER SG FISHER NC | 1996 | Hepatology1996，24，3： | 1 |
| 19 | Current management of ischemie mitral regurgitation 显示文摘 | Filsoufi F Salzberg SP Adams DH | 2005 | Mt Sinai J Med2005，72，： | 1 |
| 20 | Endothelial activation and circulating vascular adhesion molecules in alcoholic liver disease 显示文摘 | ADAMS DH BURRA P HUBSCHER SG | 1994 | Hepatology1994，19，3： | 1 |
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