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| 1 | Intensivist-based deep sedation using propofol for pediatric outpatient flexible bronchoscopy显示文摘AIM To evaluate the safety and efficacy of sedating pediatric patients for outpatient flexible bronchoscopy.METHODS A retrospective chart review was conducted for all children, age 17 years or under who underwent flexible bronchoscopy under deep sedation in an outpatient hospital-based setting. Two sedation regimens were used; propofol only or ketamine prior to propofol. Patients were divided into three age groups; infants(less than 12 mo), toddlers(1-3 years) and children(4-17 years). Demographics, indication for bronchoscopy, sedative dosing, sedation and recovery time and adverse events were reviewed.RESULTS Of the total 458 bronchoscopies performed, propofol only regimen was used in 337(74%) while propofol and ketamine was used in 121(26%). About 99% of the procedures were successfully completed. Children in the propofol + ketamine group tend to be youngerand have lower weight compared to the propofol only group. Adverse events including transient hypoxemia and hypotension occurred in 8% and 24% respectively. Median procedure time was 10 min while the median discharge time was 35 min. There were no differences in the indication of the procedure, propofol dose, procedure or recovery time in either sedative regimen. When compared to other age groups, infants had a higher incidence of hypoxemia.CONCLUSION Children can be effectively sedated for outpatient flexible bronchoscopy with high rate of success. This procedure should be performed under vigilance of highly trained providers. | Kamal Abulebda Samer Abu-Sultaneh Sheikh Sohail Ahmed Elizabeth A S Moser Renee C McKinney Riad Lutfi | 2017 | World Journal of Critical Care Medicine2017，6，4： | 8 |
| 2 | 内镜下逆行胰胆管造影术后胰腺炎、急性胆源性胰腺炎和酒精性胰腺炎患者的结局差异分析显示文摘【据《Pancreas》2019年3月报道】题:内镜下逆行胰胆管造影术后胰腺炎、急性胆源性胰腺炎和酒精性胰腺炎患者的结局差异分析(作者Kamal A等)本研究系2007年6月-2012年6月在巴基斯坦一家三级医疗中心开展一项回顾性队列研究,旨在比较急性酒精性胰腺炎(AAP)、急性胆源性胰腺炎(ABP)和内镜下逆行胰胆管造影术后胰腺炎(PEP)的临床结局。研究共纳入443例患者,其中AAP患者300例(68%),ABP患者88例(20%),PEP患者55例(12%)。与AAP(10%)、PEP(7%)相比,ABP(23%)患者长时间住院(LOHS)更为普遍,且更易出现假性囊肿、器官衰竭、干预需求和较高的病死率。系统性炎症反应综合征与>10 d的LOHS和多器官衰竭相关。既往慢性胰腺炎患者更易出现假性囊肿和较高的病死率。血清尿素氮>25 g/dl预示着>10 d的LOHS、器官衰竭、多器官衰竭和持续的器官衰竭。 | Kamal A 张娟 高润平 | 2019 | 临床肝胆病杂志2019，35，5： | 3 |
| 3 | Gastric per-oral endoscopic myotomy: Current status and future directions显示文摘Gastroparesis, or symptomatic delayed gastric emptying in the absence of mechanical obstruction, is a challenging and increasingly identified syndrome. Medical options are limited and the only medication approved by the Food and Drug Administration for treatment of gastroparesis is metoclopramide, although other agents are frequently used off label. With this caveat, first-line treatments for gastroparesis include dietary modifications, antiemetics and promotility agents, although these therapies are limited by suboptimal efficacy and significant medication side effects. Treatment of patients that fail first-line treatments represents a significant therapeutic challenge. Recent advances in endoscopic techniques have led to the development of a promising novel endoscopic therapy for gastroparesis via endoscopic pyloromyotomy, also referred to as gastric per-oral endoscopic myotomy or per-oral endoscopic pyloromyotomy. The aim of this article is to review the technical aspects of the per-oral endoscopic myotomy procedure for the treatment of gastroparesis, provide an overview of the currently published literature, and outline potential next directions for the field. | Alexander Podboy Joo Ha Hwang Linda A Nguyen Patricia Garcia Thomas A Zikos Afrin Kamal George Triadafilopoulos John O Clarke | 2019 | World Journal of Gastroenterology2019，25，21： | 3 |
| 4 | Melt rheology of polymer blends 显示文摘 | UTRACKI L A KAMAL M R | 1982 | Polymer Engineering and Science1982，22，： | 1 |
| 5 | Ageing and Diabetes: Implications for Brain Function显示文摘 | BIESSELS GJ VAN DER HEIDE LP KAMAL A | 2002 | Eur J Pharmacol(S0014-2999)2002，441，12： | 1 |
| 6 | Routing techniques in wireless sensor networks:A survey显示文摘 | Al-Karaki J N Kamal A E | 2004 | IEEE Wireless Communications2004，11，6： | 1 |
| 7 | The high-affinity HSPg0-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins显示文摘 | Dickey CA Kamal A Lundgren K | 2007 | J Clin Invest2007，117，3： | 1 |
| 8 | Genome-wide analysis of histone modifications by ChiP-on-chip显示文摘 | Huebert D J Kamal M O'Donovan A | 2006 | Methods2006，40，4： | 1 |
| 9 | The burden of strokeand transient ischemic attack in Pakistan : a community-based prevalence study显示文摘 | Kamal AK Itrat A Murtaza M | 2009 | BMC Neurol2009，9，： | 1 |
| 10 | Resveratrol induces differentiation markers expression in anaplastic thyroid carcinoma via activation of Notch1 signaling and suppresses cell growth显示文摘 | Yu XM Jaskula-Sztul R Kamal A | 2013 | Mol Cancer Ther2013，12，7： | 1 |
| 11 | Ecological vehicle control on roads with up-down slopes显示文摘 | KAMAL M A S MUKAI M MURATA J | 2011 | IEEE Trans Intell Transp Syst2011，12，3： | 1 |
| 12 | Vincristine-induced vocal cord palsy:case report and review of the literature显示文摘 | LATIFF Z A KAMAL N A JAHENDRAN J | 2010 | J Pediatr Hematol Oncol2010，32，： | 1 |
| 13 | What is the role of free radical scavengers in acute stroke?显示文摘 | Wadiwala MF Sonawalla A Kamal AK | 2012 | J Pak Med Assoc2012，62，5： | 1 |
| 14 | Long - term moisture absorption and thickness swelling behavior of recycled thermoplastics reinforced with Pinus radiata sawdust 显示文摘 | Kamal B A Shusheng P Mark P S | 2008 | Chemical Engineering Journal2008，142，2： | 1 |
| 15 | Highperformance liquid chromatographic analysis of secoisolariciresinol diglucoside and hydroxycinnamic acid glucosides in flaxseed by alkaline extraction显示文摘 | Eliasson C Kamal Eldin A Andersson R | 2003 | Journal of Chromatography A2003，1012，： | 1 |
| 16 | Intmcytoplasmic sperm injection in obstructive and non- obstructive azoospermia 显示文摘 | Mansour RT Kamal A Fahmy | 1997 | Hum Reprod1997，12，： | 1 |
| 17 | End-to-end support for statistical quality of service in heterogeneous mobile ad hoc networks 显示文摘 | Al-Karaki J N Kamal A E | 2005 | Computer Communications2005，28，18： | 1 |
| 18 | Recent developments in the design, synthesis and structure - activity relationship studies of pyrrolo benzodiazepines as DNA - interactive an- titumour antibiotics 显示文摘 | Kamal A Rao MV Laxman N | 2002 | Curr Med Chem Anticancer Agents2002，2，2： | 1 |
| 19 | A data driven failure prognostics method based on mix-ture of gaussians hidden markov models显示文摘 | Tobon-Mejia D A Kamal M Noureddine Z | 2012 | IEEE Transactions on Reliability2012，61，2： | 1 |
| 20 | Optimal path computation for autono- mous aerial vehicles 显示文摘 | Samar R Kamal W A | 2012 | Cognitive Computation2012，4，4： | 1 |
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