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85篇 您的检索式:作者名="RALPH V"
    题名 作者 年代 出处 被引量
1Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation显示文摘Splenomegaly is a well-known phenomenon typically associated with inflammation.However,the underlying cause of this phenotype has not been well characterized.Furthermore,the splenomegaly phenotype seen in lymphotoxin(LT)signaling-deficient mice is characterized by increased numbers of splenocytes and splenic neutrophils.Splenomegaly,as well as the related phenotype of increased lymphocyte counts in non-lymphoid tissues,is thought to result from the absence of secondary lymphoid tissues in LT-deficient mice.We now present evidence that mice deficient in LTα1β2 or LTβR develop splenomegaly and increased numbers of lymphocytes in non-lymphoid tissues in a microbiota-dependent manner.Antibiotic administration to LTα1β2-or LTβR-deficient mice reduces splenomegaly.Furthermore,re-derived germ-free Ltbr−/−mice do not exhibit splenomegaly or increased inflammation in non-lymphoid tissues compared to specific pathogen-free Ltbr−/−mice.By using various LTβ-and LTβR-conditional knockout mice,we demonstrate that retinoic acid-related orphan receptorγT-positive type 3 innate lymphoid cells provide the required active LT signaling to prevent the development of splenomegaly.Thus,this study demonstrates the importance of LT-mediated immune responses for the prevention of splenomegaly and systemic inflammation induced by microbiota.Yuan Zhang Tae-Jin Kim Joanna A Wroblewska Vera Tesic Vaibhav Upadhyay Ralph R Weichselbaum Alexei V Tumanov Hong Tang Xiaohuan Guo Haidong Tang Yang-Xin Fu 2018Cellular & Molecular Immunology2018,15,7:3
2Global Estimates of Ambient Fine Particulate Matter Concentrations from Satellite-Based Aerosol Optical Depth: Development and Application显示文摘van Donkelaar Aaron Martin Randall V Brauer Michael Kahn Ralph Levy Robert Verduzco Carolyn Villeneuve Paul J 2010Environmental Health Perspectives2010,,6:3
3Characterization of intrapelvic pressure during ureteropyeloscopy with ureteral access sheaths显示文摘Jamil Rehman Manoj Monga Jaime Landman David I Lee Tamer Felfela Marius C Conradie Rajamahanty Srinivas Chandru P Sundaram Ralph V Clayman 2003Urology2003,,4:2
4Reverse engineering of geometric models—an introduction显示文摘Tamás Várady Ralph R Martin Jordan Cox 1997Computer-Aided Design1997,,4:1
5Effect of Unsteady Wakes on Boundary Lay- er Separation on a Very High Lift Low Pressure Turbine Airfoil显示文摘Ralph J V 2011Journal of Turbomachinery2011,134,1:1
6显示文摘Michael V D P Randolph K B Ralph J B 1995Journal of Fluorine Chemistry1995,,71:1
7Reverse engineering of geometric models an introduction 显示文摘Tamā Várady Ralph R Martin and Jordan Cox 1997Computer-Aided Design1997,29,4:1
8A Water and Heat Management Model of Proton Exchange Membrane Fuel Cells 显示文摘Trung V Nguyen Ralph E White 1993Journal of the Electrochemical Society1993,140,8:1
9A Water and Heat Management Model for Proton-Exchange-Membrane Fuel Cells显示文摘Trung V Nguyen Ralph E White 1993Journal of Electrochemical Society August1993,140,8:1
10Malignant urachal lesions 显示文摘Curtis A Sheldon Ralph V 1984J Urol1984,131,1:1
11Malignant urachal lesions显示文摘Curtis A Sheldon Ralph V 1984Urol1984,131,1:1
12Design of Microwave Filters显示文摘Ralph levy Richard V Snyder George 2002IEEE Transactions On Microwave Theory And Techniques2002,50,3:1
13The clinical sigifcance of a single umbilical artery as an isolated finding on prenatal ult rasound显示文摘Barbara V Parilla MD Ralph KMD 1995Obstet Gynecol1995,85,:1
14Reverse engineering of geometric models—an introduction显示文摘Tamás Várady Ralph R Martin Jordan Cox 1997Computer-Aided Design1997,,4:1
15Spontaneous improvement in late rectal mucosal changes after radiotherapy for prostate cancer显示文摘Peter C O’Brien Christopher S Hamilton James W Denham Ralph Gourlay C.Ian V Franklin 2004International Journal of Radiation Oncology, Biology, Physics2004,,1:1
16Reverse engineering of geometric models: An introduction 显示文摘Tamás Várady Ralph R Martin Jordan Coxt 1997Computer-Aided Design1997,29,4:1
17A water and heat management model for proton - exchange - membrane fuel cells显示文摘Trung V N Ralph E W 1993Journal of Electrochemical Society1993,140,8:1
18Laparoscopic radical nephrectomy显示文摘MATTHES D ELSPETH M RALPH V 2000J Endourology2000,14,:1
19Technique for laparoscopic running urethrovesical anastomosis:the single knot method显示文摘Roland F Van Velthoven Thomas E Ahlering Alexandre Peltier Douglas W Skarecky Ralph V Clayman 2003Urology2003,,4:1
20Reverse engineering of geometric models-An introduction显示文摘 Martin Ralph R Cox J 1997Computer-aided Design1997,29,4:1
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