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| 1 | Liver venous deprivation versus portal vein embolization before major hepatectomy:future liver remnant volumetric and functional changes显示文摘Background:We previously showed that embolization of portal inflow and hepatic vein(HV)outflow(liver venous deprivation,LVD)promotes future liver remnant(FLR)volume(FLR-V)and function(FLR-F)gain.Here,we compared FLR-V and FLR-F changes after portal vein embolization(PVE)and LVD.Methods:This study included all patients referred for liver preparation before major hepatectomy over 26 months.Exclusion criteria were:unavailable baseline/follow-up imaging,cirrhosis,Klatskin tumor,two-stage hepatectomy.99mTc-mebrofenin SPECT-CT was performed at baseline and at day 7,14 and 21 after PVE or LVD.FLR-V and FLR-F variations were compared using multivariate generalized linear mixed models(joint modelling)with/without missing data imputation.Results:Baseline FLR-F was lower in the LVD(n=29)than PVE group(n=22)(P<0.001).Technical success was 100%in both groups without any major complication.Changes in FLR-V at day 14 and 21(+14.2%vs.+50%,P=0.002;and+18.6%vs.+52.6%,P=0.001),and in FLR-F at day 7,14 and 21(+23.1%vs.+54.3%,P=0.02;+17.6%vs.+56.1%,P=0.006;and+29.8%vs.+63.9%,P<0.001)differed between PVE and LVD group.LVD(P=0.009),age(P=0.027)and baseline FLR-V(P=0.001)independently predicted FLR-V variations,whereas only LVD(P=0.01)predicted FLR-F changes.After missing data handling,LVD remained an independent predictor of FLR-V and FLR-F variations.Conclusions:LVD is safe and provides greater FLR-V and FLR-F increase than PVE.These results are now evaluated in the HYPERLIV-01 multicenter randomized trial. | Boris Guiu François Quenet Fabrizio Panaro Lauranne Piron Christophe Cassinotto Astrid Herrerro François-Régis Souche Margaux Hermida Marie-Ange Pierredon-Foulongne Ali Belgour Serge Aho-Glele Emmanuel Deshayes | 2020 | Hepatobiliary Surgery and Nutrition2020，9，5： | 10 |
| 2 | 结直肠癌腹膜转移高风险患者进行二次探查手术加腹腔热灌注化疗与随访的比较(PRO⁃PHYLOCHIP–PRODIGE15):一项随机的3期研究显示文摘背景:如果在结直肠癌腹膜转移出现症状之前就能够早期诊断和治疗,可以提高患者生存率。我们研究的目的是在结直肠癌腹膜转移的高风险患者中,探究进行有计划的二次探查手术加腹腔热灌注化疗(hyperthermic intraperitoneal chemo-therapy,HIPEC)是否可以给患者带来生存获益。 | 张荣欣 GOéRé D GLEHEN O QUENET F | 2020 | 结直肠肛门外科2020，26，5： | 9 |
| 3 | Pseudomyxoma peritonei: A French multicentric study of 301 patients treated with cytoreductive surgery and intraperitoneal chemotherapy显示文摘 | D. Elias F. Gilly F. Quenet J.M. Bereder L. Sidéris B. Mansvelt G. Lorimier O. Glehen | 2010 | European Journal of Surgical Oncology2010，，5： | 2 |
| 4 | Oscillation and coding in a formal neural network considered as a guide for plausible simulations of the insect olfactory system 显示文摘 | Horeholle-Bossavit G Quenet B Foueart O | 2007 | Biosystems2007，89，13： | 1 |
| 5 | Tmaexamieacidin hip frae-turesurgery : arnadomized controlledtrial 显示文摘 | Zufferey P J Miquet M Quenets | 2010 | British Journal of Anaesthesia2010，104，1： | 1 |
| 6 | Thrombophilia and risk of venous thrombosis in patients with cancer显示文摘 | Decousus H Moulin N Quenet S | 2007 | Thromb Res2007，1202，： | 1 |
| 7 | Tranexamic acid in hip fracture surgery:a randomized controlled trial显示文摘 | Zufferey PJ Miquet M Quenet S | 2010 | Br J Anaesth2010，104，1： | 1 |
| 8 | Secondary debulking surgery and intraperitoneal chemotherapy in advanced or recurrent epithelial ovarian cancer显示文摘 | Plaisant N Quenet F Fabbro M | 2004 | Gynecol Obstet Fertil2004，32，5： | 1 |
| 9 | Current status and future directions in the treatment of peritoneal dissemination from colorectal carcinoma显示文摘 | Elias D Quenet F Goéré D | | 0，，04： | 1 |
| 10 | Thrombophilia and risk of venous thrombosis in patients with cancer显示文摘 | Decousus H Moulin N Quenet S | 2007 | Thromb Res2007，120，2： | 1 |
| 11 | Kin recognition in honeybees 显示文摘 | G Arnold B Quenet J M Cornuet | 1996 | Nature1996，379，： | 1 |
| 12 | Durability Study and Life-time Prediction of Baseline Proton Exchange Membrane Fuel CellUnder Severe Operating Conditions显示文摘 | Marrony M Barrera R Quenet S | 2008 | Journal of Power Sources2008，182，2： | 1 |
| 13 | The lo- cation of deepvein thrombosis as a predictive factor for recurrence and cancer discovery after proximal deep- vein thrombosis显示文摘 | LAPORTE S TARDY B QUENET S | 2003 | Haematologica2003，88，： | 1 |
| 14 | Results of Two Bi-Institutional Prospective Studies Using Intraperitoneal Oxaliplatin With or Without Irinotecan During HIPEC After Cytoreductive Surgery for Colorectal Carcinomatosis显示文摘 | Fran?ois Quenet Diane Goéré Sanket Sharad Mehta Lise Roca Fréderic Dumont Mehdi Hessissen Bernard Saint-Aubert Dominique Elias | 2011 | Annals of Surgery2011，，2： | 1 |
| 15 | Tranexamic acid in hip fracture surgery:a randomized controlled trial显示文摘 | Zufferey PJ Miquet M Quenet S | 2010 | Br J Anaesth2010，104，： | 1 |
| 16 | Poly(ADP-ribose) poly- merase-2 contributes to the fidelity of male meiosis I and spermiogenesis显示文摘 | Dantzer F Mark M Quenet D | 2006 | Proc Natl Aead Sci U S A2006，103，14： | 1 |
| 17 | Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parpl, Parp2, TP2 and HSPA2显示文摘 | Quenet D Mark M Govin J | 2009 | Exp Cell Res2009，315，16： | 1 |
| 18 | A prospective long-term study of 220 patients with a retrievable vena cava filter for secondary prevention of venous thromboembolism显示文摘 | Mismetti P Rivron-Guillot K Quenet S | 2007 | Chest2007，131，1： | 1 |
| 19 | Tranexamic acid in hip fracture surgery : a randomized controlled trial显示文摘 | Zufferey PJ Miquet M Quenet S | 2010 | Br J Anaesth2010，104，1： | 1 |
| 20 | Tranexamic acid in hip fracture surgery :a randomized controlled trial 显示文摘 | Zufferey PJ Miquet M Quenet S | 2010 | Br J Anaesth2010，104，1： | 1 |
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