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| 1 | Advanced hydrogels for the repair of cartilage defects and regeneration显示文摘Cartilage defects are one of the most common symptoms of osteoarthritis(OA),a degenerative disease that affects millions of people world-wide and places a significant socio-economic burden on society.Hydrogels,which are a class of biomaterials that are elastic,and display smooth surfaces while exhibiting high water content,are promising candidates for cartilage regeneration.In recent years,various kinds of hydrogels have been developed and applied for the repair of cartilage defects in vitro or in vivo,some of which are hopeful to enter clinical trials.In this review,recent research findings and developments of hydrogels for cartilage defects repair are summarized.We discuss the principle of cartilage regeneration,and outline the requirements that have to be fulfilled for the deployment of hydrogels for medical applications.We also highlight the development of advanced hydrogels with tailored properties for different kinds of cartilage defects to meet the requirements of cartilage tissue engineering and precision medicine. | Wei Wei Yuanzhu Ma Xudong Yao Wenyan Zhou Xiaozhao Wang Chenglin Li Junxin Lin Qiulin He Sebastian Leptihn Hongwei Ouyang | 2021 | Bioactive Materials2021，6，4： | 8 |
| 2 | Starch-based Surface-sizing Agents in Paper Industry:An Overview显示文摘Natural starch is an abundant and inexpensive polysaccharide biopolymer that is widely used as a surface-sizing agent in the paper industry.The surface sizing of paper improves its water and abrasion resistance,as well as its physical strength and printing adaptability.However,natural starch presents some disadvantages,such as high viscosity,poor fluidity,poor filmforming properties,and easy coagulation.Therefore,starch is usually modified and blended with various components to achieve better sizing performance.This article reviews approaches for the surface sizing of paper and modification of starch using enzymes or chemical methods,such as oxidation,cationization,and graft copolymerization.This article also discusses the application of starch-based multiphase systems(obtained by blending starch with various components)as surface-sizing agents. | Qiulin Wei Hao Zheng Mengni Zhu Xiao Han Yao Li Jinghui Zhou | 2021 | Paper And Biomaterials2021，6，4： | 2 |
| 3 | Effect of combined magnetic field on the eliminating inclusions from liquid aluminum alloy 显示文摘 | He Yanjie Li Qiulin Liu Wei | | Materials Letters0，65，8： | 1 |
| 4 | Characteristics of Volcanic Reservoirs and Hydrocarbon Accumulation of Carboniferous System in Junggar Basin, China显示文摘The Carboniferous volcanic reservoirs in Junggar Basin contain rich hydrocarbon resources,implying a great exploration potential,so that they have become a key replacement target for“three-dimensional exploration”.The study on the Carboniferous volcanic reservoirs and their hydrocarbon accumulation elements is significant for clarifying the orientation for exploration.In this paper,based on 37 reserves reports and 3200 reservoir test data,the Carboniferous volcanic reservoirs in Junggar Basin were discussed from the prospective of lithology and lithofacies,physical properties,reservoir types,main controls on hydrocarbon accumulation,and hydrocarbon accumulation patterns.It is found that the Carboniferous in the basin is mostly in the multi-island ocean-volcanic island arc structural-sedimentary environment,so it is geologically eligible for forming in-situ volcanic reservoirs.The volcanic rocks are:(1)mostly distributed along deep and large faults,with the lithology and lithofacies controlled by volcanic architectures;(2)dominantly lava,followed by volcaniclastic lava and volcaniclastic rock;(3)distributed in the periphery of hydrocarbon-generating sag and within the source rocks horizontally,and concentrated in the weathering crust at the top longitudinally,possibly leading to reworked weathering crust reservoir;and(4)liable to form inner reservoirs.The volcanic reservoirs can be concluded into four hydrocarbon accumulation patterns,i.e.,self-generating&self-storing in paleo-uplift and vertical migration,self-generating&self-storing in paleo-uplift and lateral migration,young-generating&old-storing in fault zone and vertical migration,and young-generating&old-storing in paleo-uplift and lateral migration.Future exploration will focus on the effective source rock development and hydrocarbon supply zones and the selfgenerating&self-storing and young-generating&old-storing patterns.The exploration prospects are determined to be the Ludong-Wucaiwan-Baijiahai slope belt and the southern slope belt of the Shaqi uplift(self-generating&self-storing pattern)in eastern Junggar,and the fault and nasal arch zone at the northwestern margin and the nasal arch zone(deep and large structure)in the Luxi area(younggenerating&old-storing pattern)in western Junggar. | Xiaozhi Wu Qiulin Guo Wei Zhang Dengfa He Xuefeng Qi Di Li | 2021 | Journal of Earth Science2021，32，4： | 1 |
| 5 | Effect of combined magnetic field on the eliminating inclusions from liquid aluminum alloy显示文摘 | Yanjie He Qiulin Li Wei Liu | 2011 | Materials Letters2011，，8： | 1 |
| 6 | Seamless and early gap healing of osteochondral defects by autologous mosaicplasty combined with bioactive supramolecular nanofiber-enabled gelatin methacryloyl(BSN-GelMA)hydrogel显示文摘Autologous mosaicplasty is a common approach used to treat osteochondral defects in clinical practice.Gap integration between host and transplanted plugs requires bone tissue reservation and hyaline cartilage regeneration without uneven surface,graft necrosis and sclerosis.However,poor gap integration is a serious concern,which eventually leads to deterioration of joint function.To deal with such complications,this study has developed a strategy to effectively enhance integration of the gap region following mosaicplasty by applying injectable bioactive supramolecular nanofiber-enabled gelatin methacryloyl(GelMA)hydrogel(BSN-GelMA).A rabbit osteochondral defect model demonstrated that BSN-GelMA achieved seamless osteochondral healing in the gap region between plugs of osteochondral defects following mosaicplasty,as early as six weeks.Moreover,the International Cartilage Repair Society score,histology score,glycosaminoglycan content,subchondral bone volume,and collagen II expression were observed to be the highest in the gap region of BSN-GelMA treated group.This improved outcome was due to bio-interactive materials,which acted as tissue fillers to bridge the gap,prevent cartilage degeneration,and promote graft survival and migration of bone marrow mesenchymal stem cells by releasing bioactive supramolecular nanofibers from the GelMA hydrogel.This study provides a powerful and applicable approach to improve gap integration after autologous mosaicplasty.It is also a promising off-the-shelf bioactive material for cell-free in situ tissue regeneration. | Hongwei Wu Yuna Shang Wei Sun Xinyi Ouyang Wenyan Zhou Jieji Lu Shuhui Yang Wei Wei Xudong Yao g Xiaozhao Wang Xianzhu Zhang Yishan Chen Qiulin He Zhimou Yang Hongwei Ouyang | 2023 | Bioactive Materials2023，，1： | 1 |
| 7 | Effect of combined magnetic field on the eliminating inclusions from liquid aluminum alloy显示文摘 | Yanjie He Qiulin Li Wei Liu | 2011 | Materials Letters2011，，8： | 1 |
| 8 | Mesh model building and migration and accumulation simulation of 3D hydrocarbon carrier system显示文摘Migration and accumulation simulation of oil and gas in carrier systems has always been a difficult subject in the quantitative study of petroleum geology. In view of the fact that the traditional geological modeling technology can not establish the interrelation of carriers in three dimensional space, we have proposed a hybrid-dimensional mesh modeling technology consisting of body(stratum), surfaces(faults and unconformities), lines and points, which provides an important research method for the description of geometry of sand bodies, faults and unconformities, the 3 D geological modeling of complex tectonic areas, and the simulation of hydrocarbon migration and accumulation. Furthermore, we have advanced a 3 D hydrocarbon migration pathway tracking method based on the hybrid-dimensional mesh of the carrier system. The application of this technology in western Luliang Uplift of Junggar Basin shows that the technology can effectively characterize the transport effect of fault planes, unconformities and sand bodies, indicate the hydrocarbon migration pathways, simulate the process of oil accumulation, reservoir adjustment and secondary reservoir formation, predict the hydrocarbon distribution. It is found through the simulation that the areas around the paleo-oil reservoir and covered by migration pathways are favorable sites for oil and gas distribution. | GUO Qiulin LIU Jifeng CHEN Ningsheng WU Xiaozhi REN Hongjia WEI Yanzhao CHEN Gang GONG Deyu YUAN Xuanjun | 2018 | Petroleum Exploration and Development2018，45，6： | 0 |
| 9 | Optimization of Supercritical Extraction Process of Laoshan Black Tea by Response Surface Methodology显示文摘[Objectives]Laoshan black tea was subjected to supercritical CO_(2) extraction. [Methods]The extraction conditions of Laoshan black tea were studied by an orthogonal experiment and optimized by response surface methodology. [Results] The optimum extraction conditions of black tea extract by supercritical CO_(2) extraction were as follows: extraction pressure 23.53 MPa, extraction time 1.73 h, and extraction temperature 49.75 ℃, with which the extract yield could reach 5.15% theoretically. [Conclusions] Based on the traditional extraction process, a supercritical extraction method optimized by response surface methodology and a unique extraction process were formed, which enriches the extraction processes and methods of natural raw materials. | Yongxin LIU Zhiguang LIU Zengyu WANG Shuai ZHANG Guofeng YU Jianhong SUN Shoutao CAO Qiulin LIU Xulun WEI Cuishu LENG Fuhua MA Xuegang LI Yinlong WANG Shoujie NIE | 2023 | Agricultural Biotechnology2023，12，1： | 0 |
| 10 | Research on the Key Technology of LTCC Pressure Sensor显示文摘这篇文章基于低温度介绍电容的压力传感器的制造技术过程共同开火陶器(LTCC ) 材料。作为牺牲的层用不同材料填满洞主要被讨论,并且二不同材料在制造被选择。充满 polyimide 的洞主要在 sintering 期间膨胀,这被发现,当充满的碳 ESL49000 材料更更好使洞扁平时。最后,在一条空气撤退隧道外面,离开的结构被设计并且测试在一布满建筑物压力环境,测量的频率线性地近似减少,压力适用,它证明不离开空气撤退隧道的设计明智。 | Xiaoyan DAI Yukun YUAN Tanyong WEI Qiulin TAN | 2015 | Photonic Sensors2015，5，3： | 0 |
| 11 | Genomic landscape of mitochondrial DNA insertions in 23 bat genomes:characteristics,loci,phylogeny,and polymorphism显示文摘The transfer of mitochondrial DNA to the nuclear genome gives rise to the nuclear DNA sequences of mitochon-drial origin(NUMTs),considered as a driving force in genome evolution.In this study,NUMTs in 23 bat genomes were investigated and compared systematically.The results showed that NUMTs existed in 22 genomes except for Noctilio leporinus,suggesting that mitochondrial fragment insertion in the nuclear genome was a common event in bat genomes.However,remarkable variations in NUMTs number,cumulative length,and proportion in the nu-clear genome were discovered across bat species.Further orthologous NUMT loci analysis of the Phyllostomidae family indicated that the NUMTs insertion events in bat genomes were homoplasy-free.The NUMTs were mainly inserted into the intergenic regions,particularly,co-localized with repetitive sequences(especially transposable el-ements).However,several NUMTs were inserted into genes,some of which were in the exon region of functional genes.One NUMT in the genome of Pteropus alecto surprisingly matched with cDNA of ATP8B3 that provided evidence of NUMTs with coding function.Phylogenic analysis on NUMTs originating from COXI and COXII loci highlighted 2 clusters of Yinpterochiroptera and Yangochiroptera for Chiroptera.Seven NUMTs from Rhinolophus ferrumequinum were amplified,and the sequencing results confirmed the reliability of the NUMT analysis.One of them was polymorphic for the presence or absence of the NUMT insertion,and each genotype of NUMT loci showed a distinct regional distribution pattern.The information obtained in this study provides novel insights into the NUMT organization and features in bat genomes and establishes a basis for further studying of the evolution of bat species. | Guojun ZHANG Deqi GENG Qiulin GUO Wei LIU Shufen LI Wujun GAO Yongfei WANG Min ZHANG Yilin WANG Yanzhen BU Hongxing NIU | 2022 | Integrative Zoology2022，17，5： | 0 |
| 12 | Study on Extraction of Effective Aroma Components from Formula Tobacco by the Supercritical CO2 Extraction Method and Its Aroma Composition显示文摘[Objectives]This study was conducted to improve the sensory quality and industrial availability of tobacco extracts.[Methods]The L9(34)design was adopted to carried out an extraction experiment,in which formula tobacco was extracted using supercritical CO2,and the extract was concentrated by vacuum distillation.Through sensory evaluation and chemical analysis,the function determination and chemical composition analysis of the tobacco extracts were carried out,and the optimal supercritical fluid extraction process was finally determined.[Results]The obtained optimal supercritical fluid extraction conditions were as follows:extraction temperature 55℃,extraction pressure 25 MPa,CO2 flow rate of 20 L/h,and entrainer of 95%ethanol.The tobacco extract obtained under the optimal conditions endowed the cigarettes with full and delicate aroma,less irritation and clean aftertaste and made the flavor of the cigarettes overall coordinated and softer,so the sensory quality was significantly improved.[Conclusions]The tobacco extract obtained by the supercritical CO2 extraction method from formula tobacco can effectively improve the quality of cigarettes. | Shoujie NIE Guangyu MENG Shoutao CAO Shuaicheng TIAN Zhiguang LIU Cuishu LENG Guofeng YU Qiulin LIU Xulun WEI Quanjiang DONG | 2020 | Agricultural Biotechnology2020，9，5： | 0 |
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