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| 1 | An update on the regulatory mechanisms of NLRP3 inflammasome activation显示文摘The NOD-,LRR-,and pyrin domain-containing protein 3(NLRP3)inflammasome is a multiprotein complex involved in the release of mature interleukin-1βand triggering of pyroptosis,which is of paramount importance in a variety of physiological and pathological conditions.Over the past decade,considerable advances have been made in elucidating the molecular mechanisms underlying the priming/licensing(Signal 1)and assembly(Signal 2)involved in NLRP3 inflammasome activation.Recently,a number of studies have indicated that the priming/licensing step is regulated by complicated mechanisms at both the transcriptional and posttranslational levels.In this review,we discuss the current understanding of the mechanistic details of NLRP3 inflammasome activation with a particular emphasis on protein-protein interactions,posttranslational modifications,and spatiotemporal regulation of the NLRP3 inflammasome machinery.We also present a detailed summary of multiple positive and/or negative regulatory pathways providing upstream signals that culminate in NLRP3 inflammasome complex assembly.A better understanding of the molecular mechanisms underlying NLRP3 inflammasome activation will provide opportunities for the development of methods for the prevention and treatment of NLRP3 inflammasome-related diseases. | Seungwha Paik Jin Kyung Kim Prashanta Silwal Chihiro Sasakawa Eun-Kyeong Jo | 2021 | Cellular & Molecular Immunology2021,18,5: | 43 |
| 2 | Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspase- mediated cell death显示文摘 | Subhadip MUKHOPADHYAY Prashanta Kumar PANDA Durgesh Nandini DAS Niharika SINHA Birendra BEHERA Tapas Kumar MAITI Sujit Kumar BHUTIA | 2014 | Acta Pharmacologica Sinica2014,35,6: | 5 |
| 3 | Lung adenocarcinoma with GGO nodules:HRCT radiological and pathological correlation显示文摘Background:Lung cancer is the most common cancer related death in the world for the both male and female as well.Adenocarcinoma is the most common pathological type which is in increasing trend.With recent advancement of screening of lung cancer with HRCT,GGO lesion has been noted frequently.GGO is a nonspecific finding that may be caused by various disorders,including inflammatory diseases,focal fibrosis,atypical adenomatous hyperplasia,bronchoalveolar carcinoma(BAC),and adenocarcinoma.This study intends to analyze the correlation between high resolutions computed tomography(HRCT)findings and the pathological findings of lung adenocarcinoma.Material and methods:Retrospective review of 16 cases of lung adenocarcinoma lesions after surgical resection.Tumors were defined as air containing type based on ratio of maximum dimension of the tumor on mediastinal window to the maximum diameter of the tumor on lung window was≤50%and as solid density if the ratio was>50%.The correlation between CT findings(homogenous/heterogeneous,airbronchogram,pleural tag,speculation,vascular involvement,pleural thickening,margin,shape)and pathological findings were investigated.Results:Of 3 air containing 2 were pre-invasive type and 1 was invasive.Among 13 solid density type all 13 were invasive type.Presence of speculation,heterogeneous appearance was found significantly associated with pathological invasion.Conclusion:Air containing type of small cells lung adenocarcinomas are preinvasive whereas solid densities are invasive.Speculation and heterogeneous are significant factor in invasive adenocarcinoma. | ACHARYA Prashanta PAUDEL Rasmita XU Qiu-zhen | 2015 | 东南大学学报(医学版)2015,34,3: | 2 |
| 4 | Effects of Tem- perature Dependent Properties in Electromagnetic Heating 显示文摘 | Mohammad Robiul Hossan Prashanta Dutta | 2012 | International Journal of Heat and Mass Transfer2012,55,1314: | 1 |
| 5 | Bifurcation analysis of a modified Leslie-Gower predator-prey model with Beddington-DeAngelis functional response and strong Allee effect显示文摘 | PALLAV P PRASHANTA M | 2014 | Mathematics and Computers in Simulation2014,97,: | 1 |
| 6 | Spatiot emporal dynamics of reaction-diffusion models of interact- ing populations 显示文摘 | Lakshmi Narayan Guin Prashanta Kumar Mandal | 2014 | Applied Mathematical Modelling2014,38,1718: | 1 |
| 7 | Analysis of a competitive prey–predator system with a prey refuge显示文摘 | Sahabuddin Sarwardi Prashanta Kumar Mandal Santanu Ray | 2012 | BioSystems2012,,3: | 1 |
| 8 | Streamlined extract preparation for Escherichia coli-based cell-free pro- tein synthesis by sonication or bead vortex mixing 显示文摘 | PRASHANTA S TROY M H BRADLEY C B | 2012 | Bio- Techniques2012,53,3: | 1 |
| 9 | Ratio-dependent predator–prey model of interacting population with delay effect显示文摘 | Sahabuddin Sarwardi Mainul Haque Prashanta Mandal | 2012 | Nonlinear Dynamics2012,,3: | 1 |
| 10 | Dielectrophoretic separation of bioparticles in microdevices: A review显示文摘 | Talukder Z. Jubery Soumya K. Srivastava Prashanta Dutta | 2014 | ELECTROPHORESIS2014,,5: | 1 |
| 11 | Thermal Analysis of Mi- crowave Assisted Bonding of Poly( Methyl Methacrylate)Substrates in Microfluidic Devices显示文摘 | Kasi B M Mohammad R H Prashanta D | 2013 | International Journal of Heat and Mass Transfer2013,58,12: | 1 |
| 12 | Numerical simulation of mixed electroosmotic/pressure driven microflows显示文摘 | Dutta Prashanta Beskok All Warburton Timothy C | 2002 | Numer Heat Transfer Part A2002,41,2: | 1 |
| 13 | A delayed ratio-dependent predator-prey model of inter- acting populations with Holling type III functional re- sponse显示文摘 | PALLAV J P PRASHANTA K M KAUSHIK K L | 2014 | Nonlinear Dynamics2014,76,1: | 1 |
| 14 | Preparation and characterization of modified polypropylene by using electron beam irradiation显示文摘 | Prashanta Dahal Youn Cheol Kim | 2013 | Journal of Industrial and Engineering Chemistry2013,19,6: | 1 |
| 15 | Acute, reproductive toxicity and two-generation teratology studies of a standardized quassinoidrich extract of Eurycoma longifolia Jack in sprague-dawley rats显示文摘 | BIN-SENG L PRASHANTA K D KIT-LAM C | 2014 | Phytother Res2014,28,: | 1 |
| 16 | Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer显示文摘 | Niharika Sinha Subhadip Mukhopadhyay Durgesh Nandini Das Prashanta Kumar Panda Sujit K. Bhutia | 2013 | Oral Oncology2013,,: | 1 |
| 17 | Standardized quassinoid-rich Eurycoma longifolia extract improved spermatogenesis and fertility in male rats via the hypothalamic-pituitary-gonadal axis显示文摘 | BIN-SENG L PRASHANTA K D KIT-LAM C | 2013 | J Ethnopharmacol2013,145,: | 1 |
| 18 | Spatial pattern in a diffusive predator-prey model with sigmoid ratio-dependent functional response显示文摘 | Lakshmi Narayan Guin Prashanta Kumar Mandal | 2014 | International Journal of Biomathematics2014,7,5: | 0 |
| 19 | Reconstruction surgery for correction of the deformity due to cancrum oris (noma)显示文摘 | Prashanta Shrestha Basant Mathema | 2008 | 中国口腔颌面外科杂志2008,6,B05: | 0 |
| 20 | 单壁碳纳米管-石墨烯杂化材料的自组装及其电学性能(英文)显示文摘以Si为基底,采用气相沉积法制备出石墨烯(G/Si)薄膜。将含1%APTES的苯溶液与G/Si密封,在115℃下加热2 h,G薄膜上自组装单层APTES膜(SAM-G/Si)。将SAM-G/Si浸渍于酸处理后的单壁碳纳米管氯仿液中,45℃干燥即得到单壁碳纳米管-石墨烯杂化材料(SWCNT-G/Si)。结果表明,具有p-型电学性能的G/Si经表面改性后呈现出n-型性能,电容性能得到提高。 | Prashanta Dhoj Adhikari Yong-hun Ko Daesung Jung Chung-Yun Park | 2015 | 新型炭材料2015,30,4: | 0 |