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| 1 | Controlled drug delivery vehicles for cancer treatment andtheir performance显示文摘Although conventional chemotherapy has been successful to some extent,the main drawbacks of chemotherapy are its poor bioavailability,high-dose requirements,adverse side effects,low therapeutic indices,development of multiple drug resistance,and non-specific targeting.The main aim in the development of drug delivery vehicles is to successfully address these delivery-related problems and carry drugs to the desired sites of therapeutic action while reducing adverse side effects.In this review,we will discuss the different types of materials used as delivery vehicles for chemotherapeutic agents and their structural characteristics that improve the therapeutic efficacy of their drugs and will describe recent scientific advances in the area of chemotherapy,emphasizing challenges in cancer treatments. | Sudipta Senapati Arun Kumar Mahanta Sunil Kumar Pralay Maiti | 2018 | Signal Transduction and Targeted Therapy2018，3，1： | 9 |
| 2 | Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles显示文摘The application of nanomedicines is increasing rapidly with the promise of targeted and efficient drug delivery.Nanomedicines address the shortcomings of conventional therapy,as evidenced by several preclinical and clinical investigations indicating site-specific drug delivery,reduced side effects,and better treatment outcome.The development of suitable and biocompatible drug delivery vehicles is a prerequisite that has been successfully achieved by using simple and functionalized liposomes,nanoparticles,hydrogels,micelles,dendrimers,and mesoporous particles.A variety of drug delivery vehicles have been established for the targeted and controlled delivery of therapeutic agents in a wide range of chronic diseases,such as diabetes,cancer,atherosclerosis,myocardial ischemia,asthma,pulmonary tuberculosis,Parkinson’s disease,and Alzheimer’s disease.After successful outcomes in preclinical and clinical trials,many of these drugs have been marketed for human use,such as Abraxane®,Caelyx®,Mepact®,Myocet®,Emend®,and Rapamune®.Apart from drugs/compounds,novel therapeutic agents,such as peptides,nucleic acids(DNA and RNA),and genes have also shown potential to be used as nanomedicines for the treatment of several chronic ailments.However,a large number of extensive clinical trials are still needed to ensure the short-term and long-term effects of nanomedicines in humans.This review discusses the advantages of various drug delivery vehicles for better understanding of their utility in terms of current medical needs.Furthermore,the application of a wide range of nanomedicines is also described in the context of major chronic diseases. | Akhand Pratap Singh Arpan Biswas Aparna Shukla Pralay Maiti | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 6 |
| 3 | Foam processing and cellular structure of polypropylene/clay nanocomposites显示文摘 | Nam Pham Hoai Maiti Pralay Okamoto Masami | 2002 | Polymer Engineering and Science2002，42，9： | 2 |
| 4 | A Hierarchical Structure and Properties of Intercalated Polypropylene/Clay Nanocornposites 显示文摘 | Pham Hoai Nam Pralay Maiti Masami Okamoto | 2001 | Polymer2001，42，： | 1 |
| 5 | An easy rapid prototyping technique with point cloud data 显示文摘 | Pal Pralay | 2001 | Rapid Prototyping Journal2001，7，2： | 1 |
| 6 | Constitutive and phloem specific expression of Allium sativum leaf agglutinin (ASAL) to engineer aphid (Lipaphis erysiml) resistance in transgenic Indian mustard (Brassica juncea) 显示文摘 | Indrajit D Pralay M Prasenjit S Krishna R and Sampa D | 2005 | Plant Science2005，169，6： | 1 |
| 7 | 显示文摘 | Pralay M Masami O | 2002 | PES2002，42，9： | 1 |
| 8 | A house of cards structure in polypropylene/clay nanocomposites under elongational flow显示文摘 | Masami Okamoto Pham Hoai Nam Pralay Maiti | 2001 | Nano Letters2001，，1： | 1 |
| 9 | Influence of Crystallization of Intercalation, Morphology and Mechanical Properties of Polypropylene/Clay Nanoeecnposites 显示文摘 | Pralay Maiti Pham Hoai Nam Masami Okamoto | 2002 | Macromolecules2002，35，： | 1 |
| 10 | Foam processing and cellular structure of polypropylene/clay nanocomposites 显示文摘 | Hoai N P Pralay M Masami O | 2002 | Polymer Engineering and Science2002，42，9： | 1 |
| 11 | A hierarchical structure and properties of intercalated polypropylene/clay nanocomposites 显示文摘 | PHAM H PRALAY M MASAMI O | 2001 | Polymer2001，42，23： | 1 |
| 12 | A strategy for machining interacting features using spatial reasoning显示文摘 | Pralay Pal Tigga A M Kurnar A | 2005 | International Journal of Machine Tools & Manufacture2005，45，3： | 1 |
| 13 | Morphology of polyurethanes at various length scale : the influence of chain structure 显示文摘 | Abhinay M Pralay M | 2011 | Journal of Applied Poly- mer Science2011，120，： | 1 |
| 14 | Foam processing and cellularstructure of polypropylene / clay nanocomposites 显示文摘 | Pham H N Pralay M Okamoto M | 2002 | Polymer Engineering and Science2002，42，9： | 1 |
| 15 | 显示文摘 | Pham Hoai Nam Pralay Maiti Masami Okamoto | 2001 | Polymer2001，42，23： | 1 |
| 16 | A hierarchical structure and properties of intercalated polypropylene/clay nanocomposites显示文摘 | Pralay Maiti Masami Okamoto | 2001 | Polymer2001，42，： | 1 |
| 17 | Validation of Companion Diagnostic for Detection of Mutations in Codons 12 and 13 of the KRAS Gene in Patients with Metastatic Colorectal Cancer: Analysis of the NCIC CTG CO.17 Trial显示文摘 | Harbison Christopher T Horak Christine E Ledeine Jean-Marie Mukhopadhyay Pralay Malone Daniel P O’Callaghan Chris Jonker Derek J Karapetis Christos S Khambata-Ford Shirin Gustafson Nancy Trifan Ovidiu C Chang Shao-Chun Ravetto Paul Green Geo | 2013 | Archives of Pathology & Laboratory Medicine2013，，6： | 1 |
| 18 | Crystallization controlled by silicate surfaces in nylon 6-clay nanocomposites显示文摘 | PRALAY M MASAMI O | 2003 | Macromolecular Materials and Engineering2003，288，5： | 1 |
| 19 | A hierarchical structure and properties of intercalated polypropylene/clay nanocomposites 显示文摘 | PHAM HOAI NAM PRALAY MATTI MASAMI OKAMOTO | 2001 | Polymer2001，42，： | 1 |
| 20 | Foam processing and cellular structure of polypropylene/clay nanocomposites显示文摘 | Pham Hoai Nam Pralay Mait I Masami Okamoto | | 0，，： | 1 |
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