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3162篇 您的检索式:作者名="PopeS"
    题名 作者 年代 出处 被引量
1评估大气细颗粒物暴露引起的全球疾病负担的一个综合风险函数显示文摘[背景]评估由于环境空气中细颗粒物(PM2.5)长期暴露引起的疾病负担,需要了解相对风险度(RR)函数的图形和幅度。然而,在世界上很多观察到高PM2.5环境浓度的地方,都缺乏足够的直接证据确定死亡RR函数的图形。[目的]建立可用于全球PM2.5暴露范围内成人死因的RR函数:缺血性心脏病(IHD)、脑血管疾病(脑卒中)、慢性阻塞性肺病(COPD)和肺癌(LC)。建立急性下呼吸道感染(ALRI)发病的RR函数,用于估算〈5岁的儿童中死亡率和健康生活损失年数。[方法]通过整合现有的来自于环境空气污染(AAP)、二手烟草烟雾、家用固体烹饪用燃料和主动吸烟(AS)等研究的RR信息,拟合综合暴露-反应(IER)模型。采用颗粒物质的吸入剂量,通过转化AS暴露来估计全年PM2.5的暴露当量。在估算全球环境PM2.5浓度的基础上,得出各国的人群归因分数(PAFs)。[结果]与以往负担评估中使用的其他7种模型相比,IER模型是一种优越的RR预测方法。在不同国家中,归因于AAP暴露的PAF百分数各不相同,分别为:IHD,2~41;脑卒中,1~43;COPD,〈1~21;LC,〈1~25;ALRI,〈1~38。[结论]我们建立了一种以细颗粒物为基础的RR模型,它通过整合来自不同类型的燃烧所产生颗粒物排放的RR信息,涵盖全球范围的暴露。当获得新的RR信息时,可以对这个模型进行更新。Richard T.Burnett C.Arden Pope III Majid Ezzati Casey Olives Stephen S.Lim Sumi Mehta Hwashin H.Shin Gitanjali Singh Bryan Hubbell Michael Brauer H.Ross Anderson Kirk R.Smith John R.Balmes Nigel G.Bruce Haidong Kan Francine Laden Annette Prüss-Ustün Michelle C.Turner Susan M.Gapstur W.Ryan Diver Aaron Cohen 何蓉 张伊人 金泰廙 2014环境与职业医学2014,31,11:80
2Associations between individual and environmental factors and habitual physical activity among older Chinese adults:A social–ecological perspective显示文摘Purpose: To examine, within a social–ecological framework, associations between multifaceted individual and environmental factors and habitual physical activity(HPA) among older Chinese adults.Methods: Through a mix of qualitative and quantitative methods, a survey instrument assessing various factors underlying 3 social–ecological dimensions of intrapersonal, interpersonal, and community and environmental resources was developed. Using a cross-sectional design, older adults(n = 1580, aged 67 ± 7 years) recruited from 10 communities in Shandong province completed the social–ecological survey of HPA. Data were analyzed using Partial Least Squares Path Modeling.Results: Factors related to intrapersonal(medical knowledge, motivation, physical function, sport skills, socioeconomic status, and education),interpersonal(social support, social activity, and social norms), and community and physical environmental resources(safety, capacity, availability of and access to physical activity facilities) were found to be significantly associated with older adults' participation in HPA.Conclusion: The findings provide an initial validation of a social–ecological approach to the study of HPA in China, suggesting that strategies aimed at promoting physical activity in older adults should address multiple levels of factors that may contribute to the likelihood of older Chinese adults being physically active.Xiangren Yi Zachary Pope Zan Gao Shumei Wang Fang Pan Jingpeng Yan Meng Liu Peipei Wu Jingjing Xu Rui Wang 2016Journal of Sport and Health Science2016,5,3:11
3The effects of a bike active video game on players' physical activity and motivation显示文摘Background: Players may not acquire adequate levels of moderate-to-vigorous physical activity(MVPA) when playing commercial video games.This study's goal was to evaluate the effects of an exercise bike video game played by using a mobile application-based exergame that was designed exclusively to promote participants' MVPA, with additional attention paid to this game's ability to promote greater situational interest.Methods: An experimental design was used with 163 students(aged 20.31 ± 1.30, 18–26 years, 61.3% male), all of whom were randomly allocated into an experimental group and a control group. Physical activity(PA) levels were assessed with Acti Graph GT3X+(Acti Graph Inc., Fort Walton Beach, FL, USA) accelerometers. The situational interest scale was used to evaluate students' situational interest in both groups.Multivariate analysis of variance was conducted to examine the differences between sedentary behavior, PA levels, and situational interest between groups. Regression analyses were also used, with the purpose being to evaluate the strength of the relationship between PA and situational interest.Results: Results revealed that the experimental group had higher degrees of sedentary behavior, light PA, total interest, instant enjoyment,exploration intention, attention demand, novelty, and challenge, whereas the control group received higher scores for MVPA(control 95.01% vs.experimental group 89.94%). Regression analysis indicated that instant enjoyment(β = 0.49, p < 0.01), exploration intention(β = 0.18, p < 0.05),and attention demand(β = 0.17, p < 0.05) were positive predictors for total interest, explaining 43% of its variance.Conclusion: A newly designed mobile application-based exergame played via an exercise bike may enhance situational interest and provide a decent level of PA for players.Denis Pasco Cédric Roure Gilles Kermarrec Zachary Pope Zan Gao 2017Journal of Sport and Health Science2017,6,1:9
4A systematic review of active video games on rehabilitative outcomes among older patients显示文摘Background: Although current research supports the use of active video games(AVGs) in rehabilitation, the evidence has yet to be systematically reviewed or synthesized. The current project systematically reviewed literature, summarized findings, and evaluated the effectiveness of AVGs as a therapeutic tool in improving physical, psychological, and cognitive rehabilitative outcomes among older adults with chronic diseases.Methods: Seven databases(Academic Search Complete, Communication & Mass Media Complete, ERIC, Psyc INFO, Pub Med, SPORTDiscus,and Medline) were searched for studies that evaluated the effectiveness of AVG-based rehabilitation among older patients. The initial search yielded 946 articles; after evaluating against inclusion criteria and removing duplicates, 19 studies of AVG-based rehabilitation remained.Results: Most studies were quasi-experimental in design, with physical functioning the primary outcome investigated with regard to the use of AVGs in rehabilitation. Overall, 9 studies found significant improvements for all study outcomes, whereas 9 studies were mixed, with significant improvements on several study outcomes but no effects observed on other outcomes after AVG-based treatments. One study failed to find any benefits of AVG-based rehabilitation.Conclusion: Findings indicate AVGs have potential in rehabilitation for older patients, with several randomized clinical trials reporting positive effects on rehabilitative outcomes. However, existing evidence is insufficient to support the advantages of AVGs over standard therapy. Given the limited number of studies and concerns with study design quality, more research is warranted to make more definitive conclusions regarding the ability of AVGs to improve rehabilitative outcomes in older patients.Nan Zeng Zachary Pope Jung Eun Lee Zan Gao 2017Journal of Sport and Health Science2017,6,1:7
5有机磷杀虫剂对M2受体磷酸化的影响显示文摘目的研究有机磷类杀虫剂对G蛋白结合受体激酶2介导的毒蕈碱乙酰胆碱m2受体磷酸化的影响和可能存在的其他作用途径。方法将纯化的毒蕈碱乙酰胆碱m2受体,G蛋白结合受体激酶-2,[γ-p32]ATP与对氧磷(PO)、氧毒死蜱(CPO)共同保温,聚丙烯酰胺凝胶电泳分离蛋白,放射性自显影检测m2受体磷酸化结果。结果氧毒死蜱完全抑制m2受体的磷酸化,其半数抑制浓度为(IC50)70μmol/L;毒死蜱也抑制m2受体的磷酸化,而对氧磷与对硫磷不抑制m2受体的磷酸化。结论不同的有机磷杀虫剂对m2受体的磷酸化有完全不同的作用;毒死蜱阻断m2受体的磷酸化,提示有机磷杀虫剂的毒性作用存在其他途径。邹黎明 Carry Pope 2005中国公共卫生2005,21,11:4
6Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association显示文摘Robert D. Brook Sanjay Rajagopalan C. Arden Pope Jeffrey R. Brook Aruni Bhatnagar Ana V. Diez-Roux Fernando Holguin Yuling Hong Russell V. Luepker Murray A. Mittleman Annette Peters David Siscovick Sidney C. Smith Laurie Whitsel Joel D. Kaufman 2010Circulation2010,,21:4
7Impact of exergaming on young children's school day energy expenditure and moderate-to-vigorous physical activity levels显示文摘Background: Although emerging research is demonstrating the potential health impact of exergaming,investigations have primarily been conducted in laboratory settings among small samples with short-term interventions.Information on the effectiveness of exergaming in underserved children's objective physical activity(PA) in population-based settings is also scarce.Moreover,most empirical studies have only included 1 type of exergame in the intervention.Therefore,this study's purpose was to investigate the long-term impact of a multigame exergaming intervention among underserved children integrated within school curricula.Specifically,this study examined the effect of exergaming on children's accelerometer-determined sedentary behavior(SB),light PA,moderate-to-vigorous PA(MVPA),and energy expenditure(EE) over 2 years as compared with regular physical education(PE) classes.Methods: A total of 261 second-and third-grade children(134 girls,127 boys; mean age 8.27 years) were recruited from 2 Texas elementary schools.Children's pre-test 3-day SB,light PA,MVPA,and EE at school were assessed in the fall of 2012.Participants were assigned to 1 of 2groups:(1) exergaming/PE group(125 min weekly of exergaming-based PA program) and (2) comparison group(125 min weekly of PE).PA(SB,light PA,and MVPA) and EE outcome variables were assessed again in 2013(post-test) and 2014(follow-up).Results: Significant time effects were observed for SB(F(1,162)=25.0,p<0.01,η~2= 0.14),light PA(F(1,162)=9.6,p<0.01,η~2= 0.06),and MVPA(F(1,162)=6.2,p=0.01,η~2= 0.04) but not for EE(F(1,162)=0.63,p>0.05,η~2= 0.004).Subsequent pairwise comparisons revealed significant increases from pre-to post-test for light PA(p<0.01),MVPA(p<0.01),and EE(p=0.02) with no changes in SB(p>0.05).Conversely,significant decreases occurred in light PA(p<0.01) from post-test to follow-up with no differences seen in MVPA(p=0.08) and EE(p=0.06) over the same time period.A significant increase was seen,however,for SB from post-test to follow-up.Conclusion: Exergaming PE can have the same positive effect on children's light PA,MVPA,and EE as regular PE.More research is necessary to discern how to promote long-term PA participation after conclusion of the intervention.Zan Gao Zachary Pope Jung Eun Lee David Stodden Nida Roncesvalles Denis Pasco Charles C.Huang Du Feng 2017Journal of Sport and Health Science2017,6,1:3
8Spin in the extended electron model显示文摘扩大电子的一个模型是适合描述经由扫描掘显微镜获得的理论模拟和试验性的结果的更多,这被发现了,但是当动态性质容易被合并时,磁性,并且特别地电子旋转性质当测量不在时由于他们的构思的 isotropy 提出一个问题。一个电子的旋转与一个磁场反应并且因此有向量的性质。然而,电子纺纱也是各向同性的,建议它没有向量的性质。在对电子旋转的描述的这中央冲突,我们相信,矛盾的性质的许多的根为量旋转粒子被测量并且要求。利用电子旋转在真实三维的空间一致地在被描述的一个模型 -- 一个扩大电子模型 -- 我们证明纺纱可以被向量描述并且仍然维持它的 isotropy。在这个框架,我们重新估计连续大小的 Stern-Gerlach 实验, Einstein-Podolsky-Rosen 实验,和效果并且在所有情况中发现相当直觉的解释。Thomas Pope Werner Hofer 2017Frontiers of physics2017,12,3:3
9PDF simulations of a bluff-body stabilized flow显示文摘Jenny P Pope S B Muradoglu M 2001J Comp Phys2001,166,:2
10Emission trading schemes: potential revenue effects, compliance costs and overall tax policy issues显示文摘Jeff Pope Anthony D. Owen 2009Energy Policy2009,,11:2
11The Association of PI3 Kinase Signaling and Chemoresistance in Advanced Ovarian Cancer显示文摘Craig P. Carden Adam Stewart Parames Thavasu Emma Kipps Lorna Pope Mateus Crespo Susana Miranda Gerhardt Attard Michelle D. Garrett Paul A. Clarke Paul Workman Johann S. de Bono Martin Gore Stan B Kaye Udai Banerji 2012Molecular Cancer Therapeutics2012,,7:2
12MULTICENTER STUDY OF EARLY LACTATE CLEARANCE AS A DETERMINANT OF SURVIVAL IN PATIENTS WITH PRESUMED SEPSIS显示文摘Ryan C. Arnold Nathan I. Shapiro Alan E. Jones Christa Schorr Jennifer Pope Elisabeth Casner Joseph E. Parrillo R. Phillip Dellinger Stephen Trzeciak 2009Shock2009,,1:2
13The Process and Benefits of Developing Prototype Climate Services——Examples in China显示文摘Changes in climate pose major challenges to society, and so decision-makers need actionable climate information to inform their planning and policies to make society more resilient to climatic changes. Climate services are being developed to provide such actionable climate information. The successful development and use of climate services benefits greatly from close engagement between developers, providers, and users of the services. The Climate Science for Service Partnership China(CSSP China) is a China–UK collaboration fostering closer engagement between climate scientists, providers of climate services, and users of climate services. We describe the process within CSSP China of co-developing climate services through trials with users to revise and improve a prototype. Examples are provided covering various scientific capabilities, user needs, and parts of China. The development process is yielding many benefits, such as increasing the engagement between providers and users, making users more aware of how climate information can be of use in their decision-making, giving the climate service providers a better understanding of the users’ requirements for climate information, and shaping future scientific research and development. In addition to the benefits, we also document some challenges that have emerged, along with ways of alleviating them. We have two key recommendations from our experiences: make the time and space for effective engagement between the users and developers of any climate service;bring the needs of the users in to the design and delivery of the climate service as early as possible and throughout the development cycle.Chris D.HEWITT Nicola GOLDING Peiqun ZHANG Tyrone DUNBAR Philip E.BETT Joanne CAMP Timothy D.MITCHELL Edward POPE 2020Journal of Meteorological Research2020,34,5:2
14Synthesis of a new salt containing polyoxometallate anion and M-Cu-S cluster cation [MS_4Cu_4(γ-MePy)_8][M_6O_19] (M = Mo,W).Crystal structure of [WS_4Cu_4(γ-MePy)_8][W_6O_19]显示文摘Reactions of (NH4)2MS4, AgBr and CuBr in r-methylpyridine produced one new compound, [MS4Cu4(r-MePy)8]M6O19] (1, M = W; 2, M = Mo), of which 1 was characterized by single crystal X-ray analysis. The crystal data: orthorhombic, Pbcn, a = 15.434(4),b= 16.732(2), c = 28.657(7) A, V = 7400.8(8) A3, Z = 4, R = 0.072 for 3121 independent data. The compound is the first example which contains both polyoxotnngstate anion and heteropolynuclear cluster cation. In the structure of the cation four edges of the tetrahedral WS42- core are coordinated by four copper atoms, giving a WS4Cu4 aggregate of approximate D2h symmetry. The differences between the reaction of Cu+ with MS42- and that of Ag+ with MS42- in pyridine and its derivatives are discussed.POPE, Michael T. Department of Chemistry, Georgetown University, Washington DC S0057, U.S.A.LANG, Jian-PingDepartment of Chemistry, Suzhou University, Suzhou, Jiangsu 215006, ChinaXIN, Xin-Quan Coordination Chemistry Institute, Nanjing University, Nanjing, Jiangsu S1000S, ChinaYU, Kai-BeiChengdu Center of Analysis and Measurement, Chinese Academy of Sciences, Chengdu, Sichuan 610041, China 1995Chinese Journal of Chemistry1995,13,1:2
15Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association显示文摘Robert D. Brook Sanjay Rajagopalan C. Arden Pope Jeffrey R. Brook Aruni Bhatnagar Ana V. Diez-Roux Fernando Holguin Yuling Hong Russell V. Luepker Murray A. Mittleman Annette Peters David Siscovick Sidney C. Smith Laurie Whitsel Joel D. Kaufman 2010Circulation2010,,21:2
16Topical imiquimod in the treatment of infantile hemangiomas: a retrospective study 显示文摘Ho NT Lansang P Pope E 2007J Am Acad Dermatol2007,56,1:1
17Review of Epidemiological evidence of health effects of particulate air pollution显示文摘Pope CA Doekery DW Sehwarz J 1995Inhalation Toxicology1995,7,1:1
18The Ethics of Counseling: A National Survey of Certified Counseling 显示文摘Pope 1993Counsel Dev1993,71,4:1
19Ion exchange theory of vanadium 显示文摘Pope M T 1968Clays Clay Miner1968,22,2:1
20Automated DNA profiling by fluorescent labeling of PCR product显示文摘Sullivan KM Pope S Gill P 1992PCR Methods Appl1992,2,1:1
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