|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 渤海环流与输运季节变化的数值模拟(英文)显示文摘渤海的风和温度层结有明显的季节变化 ,因而其环流与输运亦有明显的季节信号。以季节平均的海面气象条件和开边界的潮波系统驱动三维斜压水动力模型———HAMSOM ,模拟了渤海冬、夏季的总环流。渤海环流冬强夏弱 ,表层风漂流常被下层逆风流所补偿。深度平均环流 ,即水柱内的输运 ,流型有显著的季节变化 :冬季在渤海中部沿逆时针方向旋转 ,辽东湾顶有一个顺时针流涡 ,阻碍了湾顶水与外海水的交换 ;夏季则为一个大的贴岸的顺时针流环 ,内嵌许多局地涡旋。这些与渤黄东海海洋水文图集中给出的多年观测的环流基本相同 ,同时也被水文要素分布及耐盐浮游动物的出现所佐证。风的季节变化决定了渤海大部分海区、特别是海峡附近环流的季节变化 ,但辽东湾东岸众多的岬角涡旋却不随季节变化 ,因为它们是由潮波系统与岬角岸型变化的非线性相互作用产生的。 | 魏皓 武建平 POHLMANN Thomas | 2001 | 黄渤海海洋2001，19，2： | 26 |
| 2 | Intrahepatic distribution of hepatitis B virus antigens in patients with and without hepatocellular carcinoma显示文摘AIM: To study the intrahepatic expression of hepatitis B surface antigen(HBs Ag) and hepatitis B core antigen(HBc Ag) in chronic hepatitis B patients with and without hepatocellular carcinoma. METHODS: A total of 33 chronic hepatitis B patients(mean age of 40.3 ± 2.5 years), comprising of 14 HBe Ag positive and 19 HBe Ag negative patients; and 13 patients with hepatitis B virus related hepatocellular carcinoma(mean age of 49.6 ± 4.7 years), were included in our study. Immunohistochemical staining for HBc Ag and HBs Ag was done using standard streptavidin-biotin-immunoperoxidase technique on paraffin-embedded liver biopsies. The HBc Agand HBs Ag staining distributions and patterns were described according to a modified classification system. RESULTS: Compared to the HBe Ag negative patients, the HBe Ag positive patients were younger, had higher mean HBV DNA and alanine transaminases levels. All the HBe Ag positive patients had intrahepatic HBc Ag staining; predominantly with 'diffuse' distribution(79%) and 'mixed cytoplasmic/nuclear ' pattern(79%). In comparison, only 5% of the HBe Ag-negative patients had intrahepatic HBc Ag staining. However, the intrahepatic HBs Ag staining has wider distribution among the HBe Ag negative patients, namely; majority of the HBe Ag negative cases had 'patchy' HBs Ag distribution compared to 'rare' distribution among the HBe Ag positive cases. All but one patient with HCC were HBe Ag negative with either undetectable HBV DNA or very low level of viremia. Intrahepatic HBc Ag and HBs Ag were seen in 13(100%) and 10(77%) of the HCC patients respectively. Interestingly, among the 9 HCC patients on anti-viral therapy with suppressed HBV DNA, HBc Ag and HBs Ag were detected in tumor tissues but not the adjacent liver in 4(44%) and 1(11%) patient respectively. CONCLUSION: Isolated intrahepatic HBc Ag and HBs Ag can be present in tumors of patients with suppressed HBV DNA on antiviral therapy; that may predispose them to cancer development. | Parham Safaie Mugilan Poongkunran Ping-Ping Kuang Asad Javaid Carl Jacobs Rebecca Pohlmann Imad Nasser Daryl TY Lau | 2016 | World Journal of Gastroenterology2016，22，12： | 5 |
| 3 | A novel high resolution model without open boundary conditions applied to the China Seas: first investigation on tides显示文摘We developed a Global Ocean Circulation and Tide Model (GOCTM) with coarse grids in the open deep ocean degrading ‘smoothly’ into the highly resolved China Seas (CS) of refined grids to study the tides and circulation there.GOCTM is based on the framework of the Finite Volume approach for better mass conservation through improved transports across the discrete individual control volume.It also takes a full advantage of the geometric flexibility of unstructured mesh using a realistic global topography including the Arctic Ocean.The CS are given a special focus by refining the unstructured grids,but they are embedded into global domain naturally.Furthermore,GOCTM not only successfully avoids the treatment of the open boundaries,but also optimizes the trade-off between computational cost and model accuracy.Meanwhile,GOCTM is driven by the astronomical tide-generating potential and the secondary tide-generating potential directly,together with the wind stress and heat flux.GOCTM succeeds in reproducing the global eight principal tidal harmonic constants.Particularly,the simulated tidal results in the CS are improved compared to some other regional models with the discrepancy of 3.9 cm for M 2 tide.This idea of GOCTM can also be referred for other regional ocean study. | YU Huaming CHEN Xueen BAO Xianwen Thomas Pohlmann WU Dexing | 2010 | Acta Oceanologica Sinica2010，29，6： | 5 |
| 4 | Development of CO2 Selective Poly(Ethylene Oxide)-Based Membranes: From Laboratory to Pilot Plant Scale显示文摘气体膜分离法是从气流中分离二氧化碳(CO_2)的最有前途的技术之一。例如,采用该技术对燃烧过程中的烟气进行处理,以达到CO_2捕集和封存的目的。聚环氧乙烷嵌段共聚物能够很好地应用于膜分离技术,如Pebax~?或Poly Active^(TM)。本文采用Poly Active^(TM)作为复合薄膜的选择层。在环境温度下,当CO_2/N_2选择性超过55时,这种薄膜的CO_2渗透率高达4 m^3(STP)·m^(–2)·h^(–1)·bar^(–1)(注:1 bar=105 Pa)。这种薄膜可以按照中试规模进行生产放大,而且可以设计成不同的平面膜组件。采用单一气体渗透数据作为唯一的实验输入而开发出的仿真工具可以准确预测这种膜组件的性能。在不同的中试研究中,我们利用烟气和沼气作为原料气流,反复检测这些膜和膜组件的性能。Poly Active^(TM)在检测中显示出了稳定的分离性能,表明Poly Active^(TM)非常适用于作为膜材料进行工业规模气体处理。 | Torsten Brinkmann Jelena Lilleparg Heiko Notzke Jan Pohlmann Sergey Shishatskiy Jan Wind Thorsten Wolff | 2017 | Engineering2017，3，4： | 3 |
| 5 | Assimilation of surface currents into a regional model over Qingdao coastal waters of China显示文摘雷达穿的高频率(HF ) 测量的表面水流基于 Kalman 过滤器方法在 Qingdao 沿海的水上被吸收进一个地区性的海洋模型。一系列数字实验被执行评估数据吸收计划的性能。以便在传统的整体 Kalman 过滤器(ENKF ) 优化分析过程,一个不同分析计划把 quasiensemble 称为 Kaman 过滤器(QENKF ) 被建议。在 ENKF 和 QENKF 之间的比较两个都建议那他们能改进模仿的错误和空间结构。背景错误协变性(BEC ) 的评价被比较三个不同方法也估计:蒙特卡罗方法;加拿大的快协变性(CQC ) 方法和数据无常引擎(到期) 方法。在模型结果和 CQC 方法能更好为这沿海的海洋复制错误统计的观察表演之间的错误建模的 root-mean-square (RMS ) 的重要减小并且相应外部强迫。另外,到整体尺寸的数据吸收系统的敏感也借助于在实验使用的整体尺寸的不同规模被分析。它被发现那给计算费用和预报精确性的平衡, 50 的整体尺寸将是 Qingdao 沿海的水里的一种适当选择。 | ZHAO Jian CHEN Xueen XU Jiangling HU Wei CHEN Jinrui Pohlmann Thomas | 2013 | Acta Oceanologica Sinica2013，32，7： | 2 |
| 6 | A phase I trial of the bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC3095 in patients with advanced solid malignancies显示文摘 | G. Schwartsmann L. P. DiLeone M. Horowitz D. Schunemann A. Cancella A. S. Pereira M. Richter F. Souza A. Brondani Rocha F. H. Souza P. Pohlmann G. Nucci | 2006 | Investigational New Drugs2006，，5： | 2 |
| 7 | 原始热通量资料的海陆分布对近海SST模拟的影响显示文摘对于海洋数值模式用以计算海表温度(SST)的热通量资料,本文在插值的过程中引入了1个权重因子f,以探讨由于原始资料和数值模式的分辨率以及相应的海陆分布的不同所导致的近海SST模拟误差。对于原始资料中坐标位于海洋的点,f_O=1.0;而对于坐标位于陆地的点,f_L~[0,1]。数值实验对比了渤海和北黄海的原始数据插值结果和SST模拟结果。通过对比数值模式和原始资料的海陆分布,发现在模拟海区有相当多的模式水点被原始资料的陆点半围绕,在这些点上的插值结果受f_L的取值影响较大。本文的对比数值实验表明,当f_L分别取0.5和1.0时,对SST的模拟差异在部分海域达到了O(0.1℃)的量级,与数值模式本身的误差量级相当,是海洋数值研究中应当给予重视的误差因素。 | 宋丹 Thomas Pohlmann 陈学恩 | 2010 | 中国海洋大学学报(自然科学版)2010，40，7： | 2 |
| 8 | A novel member of the IkappaB family,human IkappaB-zeta,inhibits transactivation of p65 and its DNA binding显示文摘 | TOTZKE G ESSMANN F POHLMANN S | 2006 | J Biol Chem2006，281，12： | 1 |
| 9 | Simulation and detection of tsunami signatures in ocean surface currents measured by HF radar显示文摘 | Klaus-Werner Gurgel Anna Dzvonkovskaya Thomas Pohlmann Thomas Schlick Eric Gill | 2011 | Ocean Dynamics2011，，10： | 1 |
| 10 | The evolution of innovation: cultural backgrounds and the use of innovation models 显示文摘 | Markus Pohlmann | 2005 | Technology Analysis & Strategic Management2005，，1： | 1 |
| 11 | Discovery of the novel antithrombotic agent 5-ehloro-N- ( { ( 5 S ) -2 -oxo-3- -1,3-oxazolidin-5-yl } methyl ) thiophene-2- carboxamide( BAY 59-7939 ) : an oral, direct factor Xa inhibitor 显示文摘 | Roehrig S Straub A Pohlmann J | 2005 | J Med Chem2005，48，19： | 1 |
| 12 | Process Biochem显示文摘 | J A Rojas- Chapana C C Bartels L Pohlmann | 1998 | 33(3) :239 - 2481998，33，3： | 1 |
| 13 | The poor growth of RhodospMllum rubrum mutants lacking RubisCO is due to the accumulation of ribulose-1,5-bisphosphate 显示文摘 | Wang D Zhang Y Pohlmann E L | 2011 | J Bacteriol2011，193，13： | 1 |
| 14 | A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy显示文摘 | Guerreiro MM Vigonius U Pohlmann H | 1997 | Epilepsy Res1997，27，： | 1 |
| 15 | Decreased phosphorylation levels of cardiac myosinbinding protein-C in human and experimental heart failure显示文摘 | E1-Armouche A Pohlmann L Schlossarek S | 2007 | J Mol Cell Cardial2007，43，2： | 1 |
| 16 | Rectal cancer: assessment of response to neoadjuvant chemoradiation by dynamic contrast-enhanced MRI显示文摘 | Oberholzer K Menig M Pohlmann A | 2013 | J Magn Reson Imaging2013，38，1： | 1 |
| 17 | Parallel Analysis:A Method for Determining Significant Components 显示文摘 | Franklin S Gibson D Robertson P Pohlmann J Fralish J | 1995 | Journal of Vegetation Science1995，6，1： | 1 |
| 18 | New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae显示文摘 | WACH A BRACHAT A POHLMANN R | 1994 | Yeast1994，10，13： | 1 |
| 19 | New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae显示文摘 | Wach A Brachat A Pohlmann R | 1994 | Yeast1994，10，13： | 1 |
| 20 | Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- -1,3 -oxazolidin -5 -yl}methyl)thiophene-2-carboxamide (BAY 59-7939):an oral,direct factor Xa inhibitor显示文摘 | Roehrig S Straub A Pohlmann J | 2005 | J Med Chem2005，48，19： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员