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6篇 您的检索式:作者名="Markus Pohlmann"
    题名 作者 年代 出处 被引量
1The evolution of innovation: cultural backgrounds and the use of innovation models 显示文摘Markus Pohlmann 2005Technology Analysis & Strategic Management2005,,1:1
2The Evolution of Innovation:Cultural Backgrounds and the Use of Innovation Models显示文摘Markus Pohlmann 2005Technology Analysis&Strategic Management2005,,1:1
3Mutation D614G increases SARS-CoV-2 transmission显示文摘It has been unclear why SARS-CoV-2 with a D614G mutation in the spike protein became dominant early in the COVID-19 pandemic.A recent study by Hou et al.published in Science shows that D614G increases SARS-CoV-2 spread in cultured human nasal epithelium and enhances transmission in a hamster model.Prerna Arora Stefan Pohlmann Markus Hoffmann 2021Signal Transduction and Targeted Therapy2021,6,4:0
4Novel SARS-CoV-2 receptors:ASGR1 and KREMEN1显示文摘The interaction of the SARS-CoV-2 spike protein with the cellular receptor ACE2 is believed to be essential for viral entry into host cells・In a recent paper published in Cell Research,Gu and colleagues report that ASGR1 and KREMEN1 can also serve as SARS-CoV-2 receptors and might impact viral target cell range and antibody-mediated neutralization.Markus Hoffmann Stefan Pohlmann 2022Cell Research2022,32,1:0
5Dalbavancin:novel candidate for COVID-19 treatment显示文摘Antivirals approved for treatment of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection and the associated coronavirus disease 2019(COVID-19)are largely lacking.In a recent study in Cell Research,Wang et al.show that the clinically proven antibiotic dalbavancin blocks SARS-CoV-2 binding to its receptor ACE2 and reduces viral spread and pathogenesis in animal models.Markus Hoffmann Yeonhwa Jin Stefan Pohlmann 2021Cell Research2021,31,3:0
6Omicron:Master of immune evasion maintains robust ACE2 binding显示文摘The spike(S)protein of the SARS-CoV-2 Omicron variant is highly mutated but the impact of these mutations on viral entry into cells and its inhibition by antibodies has been unclear.A recent study published in Science by Mannar et al.now shows that these mutations are compatible with robust ACE2 binding and allow for efficient evasion of neutralizing antibodies.The emergence of SARS-CoV-2 variants has become a hallmark of the COVID-19 pandemic.Variants of concern(VOC)harbor mutations in the viral S protein that can increase transmissibility,potentially by promoting S protein binding to the cellular receptor ACE2.Markus Hoffmann Lu Zhang Stefan Pohlmann 2022Signal Transduction and Targeted Therapy2022,7,5:0
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