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| 1 | Endothelial progenitor cells in cardiovascular diseases显示文摘Endothelial dysfunction has been associated with the development of atherosclerosis and cardiovascular diseases. Adult endothelial progenitor cells(EPCs) are derived from hematopoietic stem cells and are capable of forming new blood vessels through a process of vas-culogenesis. There are studies which report correlations between circulating EPCs and cardiovascular risk fac-tors. There are also studies on how pharmacotherapies may influence levels of circulating EPCs. In this review, we discuss the potential role of endothelial progenitor cells as both diagnostic and prognostic biomarkers. In addition, we look at the interaction between cardio-vascular pharmacotherapies and endothelial progenitor cells. We also discuss how EPCs can be used directly and indirectly as a therapeutic agent. Finally, we evalu-ate the challenges facing EPC research and how these may be overcome. | Poay Sian Sabrina Lee Kian Keong Poh | 2014 | World Journal of Stem Cells2014，6，3： | 22 |
| 2 | Comparative effects of plant growth regulators on leaf and stem explants of Labisia pumila var. alata显示文摘Objective: Labisia pumila var. alata, commonly known as 'Kacip Fatimah' or 'Selusuh Fatimah' in Southeast Asia, is traditionally used by members of the Malay community because of its post-partum medicinal properties. Its various pharmaceutical applications cause an excessive harvesting and lead to serious shortage in natural habitat. Thus, this in vitro propagation study investigated the effects of different plant growth regulators (PGRs) on in vitro leaf and stem explants of L. pumila. Methods: The capabilities of callus, shoot, and root formation were evaluated by culturing both explants on Murashige and Skoog (MS) medium supplemented with various PGRs at the concentrations of 0, 1, 3, 5, and 7 mg/L. Results: Medium supplemented with 3 mg/L indole-3-butyric acid (IBA) showed the optimal callogenesis from both leaf and stem explants with (72.34±19.55)% and (70.40±14.14)% efficacy, respectively. IBA was also found to be the most efficient PGR for root induction. A total of (50.00±7.07)% and (77.78±16.47)% of root formation were obtained from the in vitro stem and leaf explants after being cultured for (26.5±5.0) and (30.0±8.5) d in the medium supplemented with 1 and 3 mg/L of IBA, respectively. Shoot formation was only observed in stem explant, with the maximum percentage of formation ((100.00±0.00)%) that was obtained in 1 mg/L zeatin after (11.0±2.8) d of culture. Conclusions: Callus, roots, and shoots can be induced from in vitro leaf and stem explants of L. pumila through the manipulation of types and concentrations of PGRs. | Anna Pick Kiong LING Kinn Poay TAN Sobri HUSSEIN | 2013 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2013，14，7： | 2 |
| 3 | Predictors of short term mortality in heart failure — Insights from the Euro Heart Failure survey显示文摘 | Periaswamy Velavan Nasrin K. Khan Kevin Goode Alan S. Rigby Poay H. Loh Michel Komajda Ferenc Follath Karl Swedberg Hugo Madeira John G.F. Cleland | 2008 | International Journal of Cardiology2008，，1： | 2 |
| 4 | Enhanced External Counterpulsation in the Treatment of Chronic Refractory Angina: A Long‐term Follow‐up Outcome from the International Enhanced External Counterpulsation Patient Registry显示文摘 | Poay HuanLoh John G.F.Cleland Amal A.Louis Elizabeth D.Kennard Jocelyn F.Cook John L.Caplin Gregory W.Barsness William E.Lawson Ozlem Z.Soran Andrew D.Michaels | 2008 | Clin Cardiol2008，，4： | 1 |
| 5 | Predictors of short term mortality in heart failure — Insights from the Euro Heart Failure survey显示文摘 | Periaswamy Velavan Nasrin K. Khan Kevin Goode Alan S. Rigby Poay H. Loh Michel Komajda Ferenc Follath Karl Swedberg Hugo Madeira John G.F. Cleland | 2008 | International Journal of Cardiology2008，，1： | 1 |
| 6 | Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function-Safe but no room for complacency显示文摘Many patients with left ventricular systolic dysfunction have concomitant mitral regurgitation(MR). Their symptoms and prognosis worsen with increasing severity of MR. Percutaneous Mitra Clip® can be used safely to reduce the severity of MR even in patients with advanced heart failure and is associated with improved symptoms, quality of life and exercise tolerance. However, a few patients with very poor left ventricular systolic function may experience significant haemodynamic disturbance in the peri-procedural period. We present three such patients, highlighting some of the potential problems encountered and discuss their possible pathophysiological mechanisms and safety measures. | Poay Huan Loh Christos V Bourantas Pak Hei Chan Nikolaj Ihlemann Fin Gustafsson Andrew L Clark Susanna Price Carlo Di Mario Neil Moat Farqad Alamgir Rodrigo Estevez-Loureiro Lars SΦndergaard Olaf Franzen | 2015 | World Journal of Cardiology2015，7，11： | 0 |
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