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| 1 | Glutamate and aspartate alleviate testicular/epididymal oxidative stress by supporting antioxidant enzymes and immune defense systems in boars显示文摘Several potential oxidative agents have damaging effects on mammalian reproductive systems.This study was conducted to investigate the effects of glutamate(Glu)and aspartate(Asp)supplementation on antioxidant enzymes and immune defense systems in the outer scrotum of boars injected with H2O2.A total of 24 healthy boars were randomly divided into 4 treatment groups:control(basal diet,saline-treated),H2O2(basal diet,H2O2-challenged outer scrotum(1 m L kg^–1 BW)),Glu(basal diet+2%Glu,H2O2-challenged),and Asp(basal diet+2%Asp,H2O2-challenged).Our results showed that both Glu and Asp supplementation improved testicular morphology and decreased the genital index in the H2O2-treated boars.Glu and Asp administration increased the antioxidant enzyme activities and affected the testicular inflammatory cytokine secretion but had no effect on sex hormone levels.Furthermore,the m RNA expression of CAT,Cu Zn SOD,and GPx4 was altered in the testes and epididymis of boars treated with Asp and Glu.Glu and Asp supplementation also modulated the expression of TGF-β1,IL-10,TNF-α,IL-6 and IL-1βin the testis and epididymis.These results indicate that dietary Glu and Asp supplementation might enhance antioxidant capacity and regulate the secretion and expression of inflammatory cytokines to protect the testes and epididymis of boars against oxidative stress. | Wenjie Tang Jian Wu Shunshun Jin Liuqin He Qinlu Lin Feijun Luo Xingguo He Yanzhong Feng Binsheng He Pingping Bing Tiejun Li Yulong Yin | 2020 | Science China(Life Sciences)2020，63，1： | 9 |
| 2 | Wogonoside inhibits tumor growth and metastasis in endometrial cancer via ER stress-Hippo signaling axis显示文摘Wogonoside,a bioactive flavonoid component derived from Scutellaria baicalensis Georgi,has been reported to inhibit tumor growth in mice bearing various types of cancer cells such as breast cancer,lung cancer,and leukemia cells.However,whether wogonoside could inhibit tumor growth of endometrial cancer has not been elucidated.In this study,we explored the function of wogonoside on tumor growth and the underlying mechanism on endometrial cancer.Firstly,we investigated the effect of wogonoside on endometrial cancer cells and found that wogonoside could significantly decrease cell proliferation and metastasis.Mechanistically,wogonoside could aggravate the extent of ER stress and upregulate the phosphorylation level of Mammalian Ste20-like kinase 1,leading to the activation of the Hippo signaling pathway.Taken together,in vitro and in vivo data demonstrated that wogonoside could be a potent inducer of ER stress and could be further developed into a promising therapy for endometrial cancer. | Shaorong Chen Zhuna Wu Yumin Ke Pingping Shu Caihong Chen Ruying Lin Qirong Shi | 2019 | Acta Biochimica et Biophysica Sinica2019，51，11： | 8 |
| 3 | Genetic diversity and DNA fingerprinting in jute(Corchorus spp.) based on SSR markers显示文摘Genetic diversity analysis and DNA finger printing are very useful in breeding programs,seed conservation and management. Jute(Corchorus spp.) is the second most important natural fiber crop after cotton. DNA fingerprinting studies in jute using SSR markers are limited. In this study, 58 jute accessions, including two control varieties(Huangma 179 and Kuanyechangguo) from the official variety registry in China were evaluated with 28 pairs of SSR primers. A total of 184 polymorphic loci were identified. Each primer detected 3 to 15 polymorphic loci, with an average of 6.6. The 58 jute accessions were DNA-fingerprinted with 67 SSR markers from the 28 primer pairs. These markers differentiated the 58 jute accessions from one another, with Co SSR305-120 and Co SSR174-195 differentiating Huangma 179 and Kuanyechangguo, respectively. NTSYS-pc2.10 software was used to analyze the genetic diversity in the 58 jute accessions. Their genetic similarity coefficients ranged from 0.520 to 0.910 with an average of 0.749, indicating relatively great genetic diversity among them. The 58 jute accessions were divided into four groups with the coefficient 0.710 used as a value for classification, consistent with their species and pedigrees. All these results may be useful both for protection of intellectual property rights of jute accessions and for jute improvement. | Liwu Zhang Rongrong Cai Minhang Yuan Aifen Tao Jiantang Xu Lihui Lin Pingping Fang Jianmin Qi | 2015 | The Crop Journal2015，3，5： | 8 |
| 4 | Variations in silicate concentration affecting photosynthetic carbon fixation by spring phytoplankton assemblages in surface water of the Strait of Malacca显示文摘The Strait of Malacca (SoM), the world's busiest sea-route, is increasingly polluted as the rapid development of world trades, affecting phytoplankton primary productivity therein. The variations of surface phytoplankton biomass, size-structure and carbon fixation were investigated across the SoM during the spring period (May 4 to 9, 2011). Chlorophyll a concentration increased from 0.12 μg/L at the northwest entrance of the SoM to a maximal 0.63 μg/L at narrowest section, and decreased to 0.10 μg/L at the southeast entrance. Photosynthetic carbon fixation by phytoplankton coincided well with Chl a biomass, and increased from 10.8 to 22.3 μg C/(L d), then decreased to 9.21 μg C/(L d); while the carbon fixation rate showed an inverse pattern to the changes of Chl a, and decreased from 87.1 to 35.5 μg C/(μg Chl a d) and increased thereafter to 95.3 μg C/(μg Chla·d). Picophytoplankton cells (<3 μm) contributed to more than 60% and 50% of the total Chl a and carbon fixation at both the entry waters; while the contributions of pico-cells decreased sharply to the minimum of 18.3% and 27.5% at the narrowest part of the SoM. In particular, our results showed that the silicate concentration positively regulated Chl a biomass and carbon fixation, reflecting that the higher silicate favoured the growth of phytoplankton and thus led to higher primary production in this strait. | LI Gang LIN Qiang SHEN Pingping NI Guangyan SONG Xingyu WANG Shengfu FAN Yanzhi HUANG Liangmin TAN Yehui | 2013 | Acta Oceanologica Sinica2013，32，4： | 4 |
| 5 | Improved Denoising Autoencoder for Maritime Image Denoising and Semantic Segmentation of USV显示文摘Unmanned surface vehicle(USV)is currently a hot research topic in maritime communication network(MCN),where denoising and semantic segmentation of maritime images taken by USV have been rarely studied.The former has recently researched on autoencoder model used for image denoising,but the existed models are too complicated to be suitable for real-time detection of USV.In this paper,we proposed a lightweight autoencoder combined with inception module for maritime image denoising in different noisy environments and explore the effect of different inception modules on the denoising performance.Furthermore,we completed the semantic segmentation task for maritime images taken by USV utilizing the pretrained U-Net model with tuning,and compared them with original U-Net model based on different backbone.Subsequently,we compared the semantic segmentation of noised and denoised maritime images respectively to explore the effect of image noise on semantic segmentation performance.Case studies are provided to prove the feasibility of our proposed denoising and segmentation method.Finally,a simple integrated communication system combining image denoising and segmentation for USV is shown. | Yuhang Qiu Yongcheng Yang Zhijian Lin Pingping Chen Yang Luo Wenqi Huang | 2020 | China Communications2020，17，3： | 2 |
| 6 | Longitudinal patterns of spring-intermonsoon phytoplankton biomass,species compositions and size structure in the Bay of Bengal显示文摘Vertical distributions of phytoplankton biomass,compositions and size structure were investigated during the spring-intermonsoon (April 22 to 30) of 2010 along transact 10 N of the Bay of Bengal,northern Indian Ocean.Surface phytoplankton biomass (Chl a) was (0.065 ± 0.009) μg/L,being greater than 80% of which was contributed by pico-phytoplankton (<3 μm).The Chl a concentration vertically increased to the maximal values at deep chlorophyll maximum (DCM) layer that shoaled eastwards from 75 to 40 m.The Chl a biomass at DCM layer generally varied between 0.2 and 0.4 μg/L,reaching the maximum of 0.56 μg/L with micro-phytoplankton cells (>20 μm) accounting for 58% and nano-(3-20 μm) or pico-cells for 15% and 27%,respectively.In particular,the cells concentration coupling well with phosphate level was observed at middle layer (75-100 m) of 87 to 89 E,dominated by micro-cells diatoms (e.g.,Chaetoceros atlanticus v.neapolitana,Chaetoceros femur and Pseudonitzschia sp.) and cyanobacteria (i.e.,Trichodesmium hildebrandtii),with the cells concentration reached as high as 4.0 × 10 4 and 4.3 × 10 4 cells/L.At the rest of the transact however,dinoflagellates (e.g.,Amphisdinium carterae and Prorocentrum sp.) were the dominant species,with the cells concentration varying from 0.3 × 10 3 to 6.8 × 10 3 cells/L.Our results also indicate that the regulation of large cells (micro-,nano-) on phytoplankton biomass merely occurred at DCM layer of the Bay. | LI Gang KE Zhixin LIN Qiang NI Guangyan SHEN Pingping LIU Huaxue YIN Jianqiang LI Kaizhi HUANG Liangmin TAN Yehui | 2012 | Acta Oceanologica Sinica2012，31，2： | 2 |
| 7 | Research progress in interface modification and thermal conduction behavior of diamond/metal composites显示文摘Diamond/metal composites are widely used in aerospace and electronic packaging fields due to their outstanding high thermal conductivity and low expansion.However,the difference in chemical properties leads to interface incompatibility between diamond and metal,which has a considerable impact on the performance of the composites.To improve the interface compatibility between diamond and metal,it is necessary to modify the interface of composites.This paper reviews the experimental research on interface modification and the application of computational simulation in diamond/metal composites.Combining computational simulation with experimental methods is a promising way to promote diamond/metal composite interface modification research. | Ping Zhu Pingping Wang Puzhen Shao Xiu Lin Ziyang Xiu Qiang Zhang Equo Kobayashi Gaohui Wu | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，2： | 2 |
| 8 | Cell-death-mode switch from necrosis to apoptosis in hydrogen peroxide treated macrophages显示文摘Cell death is typically defined either as apoptosis or necrosis. Because the consequences of apoptosis and necrosis are quite different for an entire organism, the investigation of the cell-death-mode switch has considerable clinical significance. The existence of a necrosis-to-apoptosis switch induced by hydrogen peroxide in macrophage cell line RAW 264.7 cells was confirmed by using flow cytometry and fluorescence microscopy. With the help of computational simulations, this study predicted that negative feedbacks between NF-κB and MAPKs are implicated in converting necrosis into apoptosis in macrophages exposed to hydrogen peroxide, which has significant implications. | LIN XuZhu, SUN TingZhe, CAI MeiHong & SHEN PingPing* State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, School of Life Science, Nanjing University, Nanjing 210093, China | 2010 | Science China(Life Sciences)2010，53，10： | 2 |
| 9 | Synthesis,structure and nonlinear optical properties of two novel two-photon absorption chromophores显示文摘Two triphenylamine-based derivatives that can be used as two-photon absorption chromophore,tris{4-[4-(3-trifluoromethyl-3-oxopanoyl)]phenyl}amine (1) and tris{4-[4-(3-phenyl-3-oxopanoyl)] phenyl} amine (2) were successfully synthesized and fully characterized by elemental analysis,IR,1H NMR and MS. The single crystal X-ray diffraction analysis showed that the molecules possess D-(π-A)3 structures. One-and two-photon absorption and fluorescence in various solvents were experimentally investigated. A data recording experiment proved the potential application of these chromophores. | CHENG LeHua LI Lin SUN PingPing ZHOU HongPing TIAN YuPeng TANG HuoHong | 2009 | Science China Chemistry2009，52，4： | 1 |
| 10 | Seamless Interworking of SDN and IP显示文摘 | Lin Pingping Hart J Krishnaswamy U | 2013 | ACM Sigcomm Computer Communication Review2013，43，4： | 1 |
| 11 | A Note on Reviving the Goddard Satellite-Based Surface Turbulent Fluxes (GSSTF) Dataset显示文摘Accurate sea surface flux measurements are crucial for understanding the global water and energy cycles. The oceanic evaporation, which is a major component of the global oceanic fresh water flux, is useful for predicting oceanic circulation and transport. The global Goddard Satellite-based Surface Turbulent Fluxes Version-2 (GSSTF2; July 1987–December 2000) dateset that was o?cially released in 2001 has been widely used by scientific community for global energy and water cycle research, and regional and short period data analyses. We have recently been funded by NASA to resume processing the GSSTF dataset with an objective of continually producing a uniform dataset of sea surface turbulent fluxes, derived from remote sensing data. The dataset is to be reprocessed and brought up-to-date (GSSTF2b) using improved input datasets such as a recently upgraded NCEP/DOE sea surface temperature reanalysis, and an upgraded surface wind and microwave brightness temperature V6 dataset (Version 6) from the Special Sensor Microwave Imager (SSM/I) produced by Remote Sensing Systems (RSS). A second new product (GSSTF3) is further proposed with a finer temporal (12-h) and spatial (0.25°× 0.25°) resolution. GSSTF2b (July 1987–December 2008) and GSSTF3 (July 1999–December 2009) will be released for the research community to use by late 2009 and early 2011, respectively. | Chung-Lin SHIE Long S. CHIU Robert ADLER Eric NELKIN I-I LIN Pingping XIE Feng-Chin WANG R. CHOKNGAMWONG William OLSON D. Allen CHU | 2009 | Advances in Atmospheric Sciences2009，26，6： | 1 |
| 12 | Distributed implantation of a flexible microelectrode array for neural recording显示文摘Flexible multichannel electrode arrays(fMEAs)with multiple flaments can be flexibly implanted in various patterns.It is necessary to develop a method for implanting the fMEA in different locations and at various depths based on the recording demands.This study proposed a strategy for reducing the microelectrode volume with integrated packaging.An implantation system was developed specifically for semiautomatic distributed implantation.The feasibility and convenience of the fMEA and implantation platform were verified in rodents.The acute and chronic recording results provied the effectiveness of the packaging and implantation methods.These methods could provide a novel strategy for developing fMEAs with more flaments and recording sites to measure functional interactions across multiple brain regions. | Chunrong Wei Yang Wang Weihua Pei Xinyong Han Longnian Lin Zhiduo Liu Gege Ming Ruru Chen Pingping Wu Xiaowei Yang Li Zheng Yijun Wang | 2022 | Microsystems & Nanoengineering2022，8，3： | 1 |
| 13 | Wideband diffusion metabsorber for perfect scattering field reduction显示文摘Both absorption and diffuse reflection can effectively suppress microwave backward reflection.However,the challenge of designing wideband absorptive elements with anti-phase reflection hinders the simultaneous working of the two principles.With aid of the wideband characteristic of bilateral complementary structure,we propose a strategy to design wideband absorptive elements with large reflection phase differences.For proof of concept,the proposed elements are arranged in a rectangular grid by optimizing scattering field distribution.The proposed diffusion metabsorber achieves over 20-dB scattering field reduction in the range of 8.5–20.3 GHz with good polarization stability and high angular insensitivity of up to±40°,which has been verified by real experiments.Furthermore,the proposed design strategy exhibits the potential to further reduce electromagnetic wave reflection,and the optical transparent characteristic is promising for window applications. | ZICHENG SONG PINGPING MIN JIAQI ZHU LEI YANG FENG HAN LIN | 2022 | Photonics Research2022，10，6： | 1 |
| 14 | Relay selection with feedback beamforming information through designed sector sweep report frame for mmWave WPANs显示文摘This paper proposes a novel relay selection strategy based on the feedback beamforming(BF)information through designed sector sweep(SSW)report frame for millimeter-wave(mmWave)wireless personal networks(WPANs).First,an SSW report frame compatible with IEEE 802.11ad standard is designed.Second,an approach collecting instantaneous channel state information(CSI)overheard during BF is devised.Third,with the aim of minimizing the outage probability and maximizing the overall network throughput capacity,the optimal relay selection issue for non-line-of-sight(NLoS)links is formulated as a bipartite graph,and Kuhn Munkres(KM)algorithm is provided to resolve it.Both theoretical analysis and simulation results show,with CSI considering NLoS conditions and selected relays according to the overall network throughput capacity maximization principle,the improvements achieved over opportunistic relay selection strategy in terms of overall network throughput capacity and outage probability with minimal modifications to IEEE 802.11ad. | CHU HongYun XU PingPing SUN Lin ZHANG SuHeng | 2014 | Science China(Information Sciences)2014，57，8： | 1 |
| 15 | Overexpression of UDP-glucose pyrophosphorylase gene could increase cellulose content in Jute ( Corchorus capsularis L.)显示文摘 | Gaoyang Zhang Jianmin Qi Jiantang Xu Xiaoping Niu Yujia Zhang Aifen Tao Liwu Zhang Pingping Fang LiHui Lin | 2013 | Biochemical and Biophysical Research Communications . 2013 (3-4)2013，，3： | 1 |
| 16 | Metformin reduces lipid accumulation in macrophages by inhibiting FOXO1-mediated transcription of fatty acid-binding protein 4显示文摘 | Jun Song Pingping Ren Lin Zhang Xing Li Wang Li Chen Ying H. Shen | 2010 | Biochemical and Biophysical Research Communications2010，，1： | 1 |
| 17 | Ultra-compact tunable graphene-based plasmonic multimode interference power splitter in mid infrared frequencies显示文摘In this paper, we propose graphene-based plasmonic multimode interference power splitters with ultra-compact size working in mid infrared range. Further, the arbitrary-ratio 1×2 power splitter with a size of 140 nm×232 nm, where the splitting ratio can be tuned continuously from 1:1 to 100:0, is numerically demonstrated. Meanwhile, the graphene-based arbitrary-ratio 1×2 power splitters with different frequencies and chemical potentials are also investigated. The proposed multimode interference structure with a deep nanoscale footprint might be a fundamental component of the future high density integrated plasmonic circuit or on-chip plasmonic interconnect techniques. | Pingping QIU Weibin QIU Zhili LIN Houbo CHEN Yixin TANG Jiaxian WANG Qiang KAN Jiaoqing PAN | 2017 | Science China(Information Sciences)2017，60，8： | 1 |
| 18 | CVD synthesis of nitrogen-doped graphene using urea显示文摘This work provides an effective low-cost synthesis and in-depth mechanistic study of high quality large-area nitrogen-doped graphene(NG) films. These films were synthesized using urea as nitrogen source and methane as carbon source, and were characterized by scanning electron microscopy(SEM), Raman spectroscopy and X-ray photoelectron spectroscopy(XPS). The N doping level was determined to be 3.72 at.%, and N atoms were suggested to mainly incorporated in a pyrrolic N configuration. All distinct Raman peaks display a shift due to the nitrogen-doping and compressive strain. The increase in urea concentration broadens the D and 2D peak's Full Width at Half Maximum(FWHM), due to the decrease of mean free path of phonons. The N-doped graphene exhibited an n-type doping behavior with a considerably high carrier mobility of about 74.1 cm2/(V s), confirmed by electrical transport measurements. | ZHANG CanKun LIN WeiYi ZHAO ZhiJuan ZHUANG PingPing ZHAN LinJie ZHOU YingHui CAI WeiWei | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，10： | 1 |
| 19 | Design of protograph LDPC codes for partial response channels 显示文摘 | FANG Yi CHEN Pingping WANG Lin | 2012 | IEEE Transactions on Communications2012，60，10： | 1 |
| 20 | ASIC:An Architecture for Scalable Intra-domain Control in OpenFlow显示文摘 | Pingping Lin Jun Bi Hongyu Hu | 2012 | CFI''12Proceedings of the 7th International Conference on Future Internet Technologies2012，，： | 1 |
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