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| 1 | Antrodia Cinnamomea ameliorates neointimal formation by inhibiting infl ammatory cell infi ltration through downregulation of adhesion molecule expression in vitro and in vivo显示文摘The increased vascular infl ammation is a key event in the development of atherosclerotic lesions.Antrodia cinnamomea has been shown to promote anticancerogenic activity through decreasing infl ammation.However,the potential role of A.cinnamomea in cardiovascular diseases remains unexplored.Herein,using carotid arterial ligation models,we found that ethanol extract from A.cinnamomea(EEAC)signifi cantly inhibited neointimal hyperplasia in a dose-dependent manner,accompanied with the reduced expression of activated p65 and infl ammatory cytokines.We also show that EEAC ameliorated TNF-α-induced phosphorylation of p65 and pro-infl ammatory cytokine expression in both vascular smooth muscle cells(VSMCs)and macrophages in vitro.Mechanistically,EEAC suppressed expression levels of intercellular adhesion molecule-1(ICAM-1)and vascular cell adhesion molecule(VCAM-1)in VSMCs,which attenuates the ability of monocytes/macrophages adhesion to VSMCs.Furthermore,the expression level of these adhesion molecules and infi ltration of monocytes/macrophages were also decreased in neointimal VSMCs of arteries pretreated with EEAC.Altogether,our results reveal a novel function of A.cinnamomea in suppressing vascular infl ammation upon ligation injury during neointimal formation,likely through inhibition of infl ammatory cell infi ltration via downregulating the adhesion molecules in VSMCs.Thus,A.cinnamomea may offer a pharmacological therapy to slow down disease progression in patients with vascular injury. | Yan Zhang Aijin Ma Hao Xi Ning Chen Rong Wang Chenhui Yang Jinbang Chen Pin Lü Fuping Zheng Wenyi Kang | 2021 | Food Science and Human Wellness2021，10，4： | 4 |
| 2 | Henry Kissinger’s On China显示文摘HENRY Kissinger’s latest book, On China, an ambitious combination of his memoirs as a professional diplomat and his understanding of Chinese politics, culture and history, attempts to f it Chinese leaders’ strategic intentions and diplomatic approaches into a historical and cultural framework. Opening with a look into the deep past, the book discusses the important in uence of | Lü PIN | 2011 | China Today2011，60，10： | 3 |
| 3 | A Generic Plug-and-Play Navigation Fusion Strategy for Land Vehicles in GNSS-Denied Environment显示文摘Achieving accurate navigation information by integrating multiple sensors is key to the safe operation of land vehicles in global navigation satellite system(GNSS)-denied environment.However,current multi-sensor fusion methods are based on stovepipe architecture,which is optimized with custom fusion strategy for specific sensors.Seeking to develop adaptable navigation that allows rapid integration of any combination of sensors to obtain robust and high-precision navigation solutions in GNSS-denied environment,we propose a generic plug-and-play fusion strategy to estimate land vehicle states.The proposed strategy can handle different sensors in a plug-and-play manner as sensors are abstracted and represented by generic models,which allows rapid reconfiguration whenever a sensor signal is additional or lost during operation.Relative estimations are fused with absolute sensors based on improved factor graph,which includes sensors’error parameters in the non-linear optimization process to conduct sensor online calibration.We evaluate the performance of our approach using a land vehicle equipped with a global positioning system(GPS)receiver as well as inertial measurement unit(IMU),camera,wireless sensor and odometer.GPS is not integrated into the system but treated as ground truth.Results are compared with the most common filtering-based fusion algorithm.It shows that our strategy can process low-quality input sources in a plug-and-play and robust manner and its performance outperforms filtering-based method in GNSS-denied environment. | LAI Jizhou BAI Shiyu XU Xiaowei Lü Pin | 2019 | Transactions of Nanjing University of Aeronautics and Astronautics2019，36，2： | 2 |
| 4 | l -Carnitine: An adequate supplement for a multi-targeted anti-wasting therapy in cancer显示文摘 | Sílvia Busquets Roberto Serpe Míriam Toledo Angélica Betancourt Enrica Marmonti Marcel Orpí Fabrizio Pin Eva Capdevila Clelia Madeddu Francisco J. López-Soriano Giovanni Mantovani Antonio Macciò Josep M. Argilés | 2012 | Clinical Nutrition2012，，6： | 2 |
| 5 | Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese显示文摘 | Judith Aron-Wisnewsky Caroline Minville Joan Tordjman Patrick Lévy Jean-Luc Bouillot Arnaud Basdevant Pierre Bedossa Karine Clément Jean-Louis Pépin | 2011 | Journal of Hepatology2011，，1： | 2 |
| 6 | Current Status and Prospect of Stent Placement for May-Thurner Syndrome显示文摘Stent implantation has been proven to be safe and has become the first-line intervention for May-Thumer syndrome(MTS),with satisfactory mid-term patency rates and clinical outcomes.Recent research has demonstrated that catheter-directed thrombolysis is the preferred strategy when MTS is combined with deep vein thrombosis after self-expanding stent placement.However,the stent used for the venous system was developed based on the experience obtained in the treatment of arterial disease.Consequently,relatively common corresponding complications may come along later,which include stent displacement,deformation,and obstruction.Different measures such as adopting a stent with a larger diameter,improving stent flexibility,and increasing stent strength have been employed in order to prevent these complications.The ideal venous stent is presently being evaluated and will be introduced in detail in this review. | Qin LIU Fang LIU Ping LÜ Hong-xiao WU Pin YE Yun YOU Zhong YAO | 2021 | Current Medical Science2021，41，6： | 2 |
| 7 | Alkane oxidation with hydrogen peroxide catalyzed homogeneously by vanadium-containing polyphosphomolybdates 显示文摘 | Gonzalez L Shul′pin G B | 2001 | Appl Catal A:Gen2001，217，： | 1 |
| 8 | An efficient route to aqueous phase synthesis of nanocrystallineγ-Al2O3 with high porosity:from stable boehmite colloids to large pore mesoporous alumina显示文摘 | Bleta R Alphonse P Pin L | 2012 | Journal of Colloid and Interface Science2012，367，1： | 1 |
| 9 | The estimation of wind exposure for windthrow hazard rating: comparison be- tween Strongblow, MC2, Topex and a wind tunnel study 显示文摘 | RUEL J C PIN D SPACEK L et ol | 1997 | Forestry1997，70，3： | 1 |
| 10 | A practical tool- kit for computational steering 显示文摘 | Pickles S M Haines R Pinning R L | 2005 | Philosophical Transac- tions of the Royal Society A: Mathematical Physical and Engineering Sciences''2005，363，1833： | 1 |
| 11 | Early diagnosis of scoliosisbased on school-screening显示文摘 | Pin L Mo L Lin L | 1985 | The Journal of Bone & JointSurgery1985，67，8： | 1 |
| 12 | Congenital multifocal rhabdoid tumor: a case with peculiar biological behavior and different response to treatment according to location (central nervous system and kidney) 显示文摘 | Pin L Milanaccio C Maseelli S | 2014 | Cancer Genet2014，207，： | 1 |
| 13 | Profile of circulating cytokines: Impact of OSA, obesity and acute cardiovascular events显示文摘 | Dries Testelmans Renaud Tamisier Gilles Barone-rochette Jean-Philippe Baguet Pascale Roux-Lombard Jean-Louis Pépin Patrick Lévy | 2013 | Cytokine2013，，： | 1 |
| 14 | Obstructive sleep apnea and ath- erosclerosis显示文摘 | Lévy P Pépin JL Arnaud C etal | 2009 | Progress in Cardiovascular Diseases2009，51，： | 1 |
| 15 | Intermittent hypoxia-activated cyclooxygenase pathway: role in atherosclerosis显示文摘 | Elodie Gautier-Veyret Claire Arnaud Magnus B?ck Jean-Louis Pépin Marcelo H. Petri Jean-Philippe Baguet Renaud Tamisier Patrick Lévy Fran?oise Stanke-Labesque | 2013 | European Respiratory Journal2013，，： | 1 |
| 16 | Sixteen years' experience with long-term follow-up显示文摘 | Flynn J C Matthews J G Benoit R L Blind pinning of displaced supracondylar fractures of the humerus in children | 1974 | JBone Joint Surg Am1974，56，2： | 1 |
| 17 | Environmental monitoring by gene expression biomarkers in Barbus graellsii: Laboratory and field studies 显示文摘 | Quiro L Pin B J Sole M | 2007 | Chemosphere2007，67，： | 1 |
| 18 | Long-term oxyen therapy at home:compliance with medical prescription and effective use of the-rapy显示文摘 | Pépin J L Barjhoux C E Deschaux C | 1996 | Chest1996，109，5： | 1 |
| 19 | Tumor markers in lung cancer:does the method of obtaining the cut-off point and reference population influence diagnostic yield?显示文摘 | Pin T C Zapata I T Lpez J B | 1999 | Clin Biochem1999，32，6： | 1 |
| 20 | Phylogenetic relationship of Ale:candrium tamiyavanichii (Dinophyceae) to other Alexandrium species based on ribosomal RNA gene sequences显示文摘 | USUP G PIN L C AHMAD A | 2002 | Harmful Algae2002，1，1： | 1 |
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