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| 1 | 急性缺血性卒中患者早期处理指南:美国心脏协会/美国卒中协会对医疗专业人员的指南显示文摘背景和目的作者提供了关于成年急性缺血性卒中患者评估和治疗方面的现有证据和处理推荐的一份概述。目标读者为涉及急性缺血性卒中患者发病48h内诊治的院前诊疗人员、医生、综合医疗保健人员和医院管理者。该指南将取代先前的2007年版指南及其2009年更新版。方法著述委员会成员由美国卒中协会卒中委员会的科学声明监督委员会指定,代表各个领域的医疗专家。在形成共识的整个过程中,严格遵循美国心脏协会的利益冲突原则。委员会成员被分配给与其专业领域相关的内容,对卒中文献进行回顾,重点为前一版指南发表之后的文献,然后按照美国心脏协会卒中委员会的证据强度分级方案起草推荐意见。结果本指南的目的是减少卒中相关的残疾和死亡。本指南支持卒中医疗体系的全局性概念以及从患者识别、急救医疗服务激活、转送和分诊到急诊室和卒中单元内最初数小时诊治的卒中诊治细节。本指南讨论了早期卒中评估和一般治疗、缺血性卒中治疗、特殊干预措施,如再灌注策略以及脑复苏的一般生理学干预原则。结论由于许多推荐意见基于有限的证据,还迫切需要对急性缺血性卒中的治疗做进一步的研究。 | Edward C. Jauch Jeffrey L. Saver Harold P. Adams Askiel Bruno J.J. (Buddy) Connors Bart M. Demaerschalk Pooja Khatri Paul W. McMullan Jr, Adnan I. Qureshi Kenneth Rosenfield Phillip A. Scott Debbie R. Summers David Z. Wang Max Wintermark Howard Yonas 李海峰(译) 岳耀先(译) 王琦(译) 张贤军(译) 丁晓君(译) | 2013 | 国际脑血管病杂志2013，21，7： | 17 |
| 2 | 导致成人与儿童患者30天脑室腹腔分流失败的原因分析(英文)显示文摘OBJECTIVE The aim of this study was to provide a comprehensive benchmark of 30-day ventriculoperitoneal(VP)shunt failure rates for a single institution over a 5-year study period for both adult and pediatric patients,to compare this with the results in previously published literature,and to establish factors associated with shunt failure.METHODS A retrospective database search was undertaken to identify all VP shunt operations performed in a single,regional neurosurgical unit during a 5-year period.Data were collected regarding patient age,sex,origin of hydrocephalus,and whether the shunt was a primary or secondary shunt.Operative notes were used to ascertain the type of valve inserted,which components of the shunt were adjusted/replaced(in revision cases),level of seniority of the most senior surgeon who participated in the operation,and number of surgeons involved in the operation.Where appropriate and where available,postoperative imaging was assessed for grade of shunt placement,using a recognized grading system.Univariate and multivariate models were used to establish factors associated with early(30-day)shunt failure.RESULTS Six hundred eighty-three VP shunt operations were performed,of which 321 were pediatric and 362 were adult.The median duration of postoperative follow-up for nonfailed shunts(excluding deaths)was 1263 days(range 525-2226 days).The pediatric 30-day shunt failure rates in the authors'institution were 8.8%for primary shunts and 23.4%for revisions.In adults,the 30-day shunt failure rates are 17.7%for primary shunts and 25.6%for revisions.In pediatric procedures,the number of surgeons involved in the operating theater was significantly associated with shunt failure rate.In adults,the origin of hydrocephalus was a statistically significant variable.Primary shunts lasted longer than revision shunts,irrespective of patient age.CONCLUSIONS A benchmark of 30-day failures is presented and is consistent with current national databases and previously published data by other groups.The number of surgeons involved in shunt operations and the origin of the patient's hydrocephalus should be described in future studies and should be controlled for in any prospective work.The choice of shunt valve was not a significant predictor of shunt failure.Most previous studies on shunts have concentrated on primary shunts,but the high rate of early shunt failure in revision cases(in both adults and children)is perhaps where future research efforts should be concentrated. | Anderson IA Saukila LF Robins JMW Akhunbay-Fudge CY Goodden JR Tyagi AK Phillips N Chumas PD | 2018 | 中华神经外科疾病研究杂志2018，17，3： | 3 |
| 3 | Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A,Mg2+Ap5A,and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+显示文摘 | Berry MB Phillips GN Jr | 1998 | Proteins1998，32，3： | 1 |
| 4 | Fatigue-life pre diction methodology using small-crack theory 显示文摘 | NEWMAN Jr J C PHILLIPS E P SWAIN M | 1999 | International Journal of Fatigue1999，21，2： | 1 |
| 5 | Fatigue-life prediction methodology using small crack theory显示文摘 | Newman J C Jr Phillips E P Swain M H | 1999 | International Journal of Fatigue1999，21，2： | 1 |
| 6 | The molecular structure of green fluorescent protein 显示文摘 | Yang F Moss L G Phillips G N Jr | 1996 | Nat Biotechnol1996，14，10： | 1 |
| 7 | Induced myopia associated with increased scleral creep in chick and tree shrew eyes显示文摘 | Phillips JR Khalaj M McBrien NA | 2000 | Invest Ophthalmol Vis Sci2000，41，8： | 1 |
| 8 | Verbal fluency performance in dementia of the Alzheimer's type:a meta-analysis显示文摘 | Henry JD Crawford JR Phillips LH | | 0，，： | 1 |
| 9 | Dandy-Walker malformation complex显示文摘 | Phillips J Mahony BS Siebert JR | 2006 | Obstet Gynecol2006，107，3： | 1 |
| 10 | Depression as a predictor of disease progression and mortality in cancer patients:a meta-analysis显示文摘 | Satin JR Linden W Phillips MJ | 2009 | Cancer2009，115，22： | 1 |
| 11 | Induced myopia associated with increased sclera creep in chick and tree shrew eyes 显示文摘 | Phillips JR Khalaj M McBrien NA | 2000 | Invest Ophthalmol Vis Sci2000，8，： | 1 |
| 12 | Laparoscopy identifies unexpected groin hernias显示文摘 | Crawford DL Hiatt JR Phillips EH | 1998 | Am Surg1998，64，10： | 1 |
| 13 | Factors affectingthe product ratio of the carbon-oxygen reaction (II):Reaction temperature 显示文摘 | Phillips R Vastola F J Walker Jr P L | 1970 | Carbon1970，8，2： | 1 |
| 14 | Nonaldehyde sterilization of biologic tissue for use in implantable medical devices 显示文摘 | Moore MA Mcllroy BK Phillips RE Jr | 1997 | ASAIO J1997，43，1： | 1 |
| 15 | There ismore than one kind of myofibroblast:Analysis of CD34 expression in benign,in situ,and invasive breast lesions显示文摘 | Chauhan H Abraham A Phillips JR | 2003 | J Clin Pathol2003，56，4： | 1 |
| 16 | Electroencephalographic and psychometric differences between boys with and without attention deficit hyperactivity disorder(ADHD): a pilot study 显示文摘 | Cox DJ Kovatchev BP Morris JB Jr Phillips C Hill RJ Merkel L | 1998 | Appl Psychophysiol Biofeedback1998，23，3： | 1 |
| 17 | , and Soo Jung Kim, Essential Concepts of Engineering Design Curriculum in Secondary Technology Education显示文摘 | Robert Wicklein Phillip Cameron Smith Jr | 2009 | Journal of Technology Education2009，20，2： | 1 |
| 18 | Sulfurized vegetable oil products as lubricant additives显示文摘 | Kammann Karl P Jr Phillips I Astrid | 1984 | JAOCS1984，62，5： | 1 |
| 19 | Photochemistry and radiation chemistry of cellulose 显示文摘 | Phillips G O Arthur Jr J C | 1985 | Cellulose chemistry and its applications1985，12，： | 1 |
| 20 | Postoperative re- flux gastritis: pathophysiology and long-term outcome after roux-en-y diversion 显示文摘 | Malagelada JR Phillips SF Shorter RG | 1985 | Ann Intern Med1985，103，2： | 1 |
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