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| 1 | Maximum standardized uptake value on PET/CT in preoperative assessment of lymph node metastasis from thoracic esophageal squamous cell carcinoma显示文摘The presence of lymph node metastasis is an important prognostic factor for patients with esophageal cancer.Accurate assessment of lymph nodes in thoracic esophageal carcinoma is essential for selecting appropriate treatment and forecasting disease progression.Positron emission tomography combined with computed tomography(PET/CT)is becoming an important tool in the workup of esophageal carcinoma.Here,we evaluated the effectiveness of the maximum standardized uptake value(SUVmax)in assessing lymph node metastasis in esophageal squamous cell carcinoma(ESCC)prior to surgery.Fifty-nine surgical patients with pathologically confirmed thoracic ESCC were retrospectively studied.These patients underwent radical esophagectomy with pathologic evaluation of lymph nodes.They all had18F-FDG PET/CT scans in their preoperative staging procedures.None had a prior history of cancer.The pathologic status and PET/CT SUVmax of lymph nodes were collected to calculate the receiver operating characteristic(ROC)curve and to determine the best cutoff value of the PET/CT SUVmax to distinguish benign from malignant lymph nodes.Lymph node data from 27 others were used for the validation.A total of 323 lymph nodes including 39 metastatic lymph nodes were evaluated in the training cohort,and 117lymph nodes including 32 metastatic lymph nodes were evaluated in the validation cohort.The cutoff point of the SUVmax for lymph nodes was 4.1,as calculated by ROC curve(sensitivity,80%;specificity,92%;accuracy,90%).When this cutoff value was applied to the validation cohort,a sensitivity,a specificity,and an accuracy of 81%,88%,and 86%,respectively,were obtained.These results suggest that the SUVmax of lymph nodes predicts malignancy.Indeed,when an SUVmax of 4.1 was used instead of 2.5,FDG-PET/CT was more accurate in assessing nodal metastasis. | Amos JM Ela Bella Ya-Rui Zhang Wei Fan Kong-Jia Luo Tie-Hua Rong Peng Lin Hong Yang Jian-Hua Fu | 2014 | Chinese Journal of Cancer2014，33，4： | 3 |
| 2 | Down-regulation of hexokinase Ⅱ by RNAi sensitizes human colorectal cancer cells to 5-fluorouracil 显示文摘 | Peng QP Zhou JM Liang HJ | 2008 | Chemotherapy2008，54，5： | 1 |
| 3 | Expression of tyrosine hydroxylase in lymphocytes and effect of endogenous catecholamines on lymphocyte function显示文摘 | Peng YP Jiang JM | 2004 | Neuroimmunomodulation2004，11，1： | 1 |
| 4 | Lamina-specific anatomic magnetic resonance imaging of the human retina 显示文摘 | Zhang Y Nateras OS Peng Q Kuranov RV Harrison JM Milner TE et at | 2011 | Invest Ophthalmol Vis Sci2011，52，10： | 1 |
| 5 | Effect of KAI1 gene on growth and invasion of human hepatocetlular carcinoma MHCC97-H cells显示文摘 | SI SH YANG JM PENG ZH | 2004 | World J Gastroenterol2004，10，14： | 1 |
| 6 | Toll-like receptor 2 signaling in CD4(+)T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease显示文摘 | Reynolds JM Pappu BP Peng J | | 0，，5： | 1 |
| 7 | KAI1 gene suppresses invasion and metastasis of hepatocellular carcinoma MHCC97-H cells in vitro and in animal models显示文摘 | YANG JM PENG ZH SI SH | 2008 | Liver Int2008，28，1： | 1 |
| 8 | KAI1 gene suppresses invasion and metastasis of hepatocellular carcinoma MHCC97-H cells in vitro and in animal models 显示文摘 | Yang JM Peng ZH Si SH | 2008 | Liver Int2008，28，1： | 1 |
| 9 | Raf activation by Rasand promotion of cellular metastasis require phosphoryla-tion of prohibitin in the raft domain of the plasma mem-brane 显示文摘 | Chiu CF Ho MY Peng JM | 2013 | Oncogene2013，32，6： | 1 |
| 10 | Recombinant viral protein pro- motes apoptosis and suppresses invasion of ovarian adenarcinoma cells by targeting c511 integrin to down-regulate Akt and MMP-2 显示文摘 | Peng JM Chen YH Hung SW | 2012 | Br J Pharmacol2012，165，2： | 1 |
| 11 | Rates and causes of intraoperative removal of foldable and rigid intraocular lenses: clinicopathological analysis of 100 cases 显示文摘 | Schmidbauer JM Peng Q Apple DJ Pandey SK Escobar- Gomez M Auffarth GU | 2002 | J Cataract Refract Surg2002，28，7： | 1 |
| 12 | Tol-like receptor 2 signaling in CD4(+)T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease显示文摘 | Reynolds JM Pappu BP Peng J | | 0，，05： | 1 |
| 13 | Neurophysiology of cancer pain显示文摘 | Regan JM Peng P | 2000 | cancer control2000，7，2： | 1 |
| 14 | Fractal mechanisms and heart rate dynamics: long-range correlations and their breakdown with disease 显示文摘 | Peng CK Havlin S Hausdorff JM | 1996 | J Electrocardiology1996，，： | 1 |
| 15 | Pharmacokinetic study of salvianolic acid A in rat after intravenous administration of Danshen injection 显示文摘 | Hou YY Peng JM Chao RB | 2007 | Bi- omed Chromatogr2007，21，6： | 1 |
| 16 | Expression of tyrosine hydroxylase in lymphocytes and effect of endogenous catecholamines on lymphocyte function显示文摘 | Qiu YH Peng YP Jiang JM | 2004 | Neuroimmunomodulation2004，11，2： | 1 |
| 17 | Raf activation by Ras and promo- tion of cellular metastasis require phosphorylation of prohibitin in the raft domain of the plasma membrane 显示文摘 | Chiu CF Ho MY Peng JM | 2013 | Oncogene2013，32，6： | 1 |
| 18 | In- vestigation of Danshen and related medicinal plants in China 显示文摘 | Li MH Chen JM Peng Y Wu Q Xiao PG | 2008 | J Ethnopharmacol2008，120，3： | 1 |
| 19 | GAL-021, a new intravenous BKCa-channel blocker, is well tolerated and stimulates ventilation in healthy volunteers 显示文摘 | McLeod JF Leempoels JM Peng SX | 2014 | Br J Anaesth2014，113，5： | 1 |
| 20 | Use of 5-aminolevu- linic acid esters to improve photodynamic therapy on cells in culture显示文摘 | Gaullier JM Berg K Peng Q | 1997 | CancerRes1997，57，8： | 1 |
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