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| 1 | 儿童惊厥性癫痫持续状态的发病率、病因及短期临床结局:基于人群的前瞻性研究显示文摘Background:Convulsive status epilepticus is the mostcommon childhood medical neurological emergency,and is associated with significant morbidity and mortality. Mostdata for this disorder are from mainly adult populations and might not be relevant to childhood. Thus we undertook the North London Status Epilepticus in Childhood Surveillance Study (NLSTEPSS):a prospective,population-based study of convulsive status epilepticus in childhood,to obtain a uniquely paediatric perspective.Methods:Clinical and demographic data for episodes of childhood convulsive status epilepticus that took place in north London were obtained through a clinical network that covered the target population. We obtained these data from anonymised copies of a standardised admission proforma; accident and emergency,nursing,ambulance,and intensive-care unit notes; and interviews with parents,medical,nursing,and paramedic staff. We investigated ascertainment using capture-recapture modelling.Findings:Of 226 children enrolled,176 had a first ever episode of convulsive status epilepticus. We estimated that ascertainment was between 62%and 84%.The ascertainment-adjusted incidence was between 17 and 23 episodes per 100 000 per year. 98 (56%,95%CI 48-63) children were neurologically healthy before their first ever episode and 56 (57%,47-66) of those children had a prolonged febrile seizure. 11 (12%,6-18) of children with first ever febrile convulsive status epilepticus had acute bacterial meningitis. Conservative estimation of 1-year recurrence of convulsive status epilepticus was 16%(10-24%). Case fatality was 3%(2-7%). Interpretation:Convulsive status epilepticus in childhood is more common,has a different range of causes,and a lower risk of death than that in adults. These paediatric data will help inform management of convulsive status epilepticus and appropriate allocation of resources to reduce the effects of this disorder in childhood. | Chin R.F. Neville B.G. Peckham C. 张振 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，0，12： | 2 |
| 2 | Membrane unpacking and the rapid disposal of apoptotic cells显示文摘 | Ashman R F Peckham D Alhasan S | | 0，，： | 1 |
| 3 | Carcinogenesis studies of benzophenone in rats and mice显示文摘 | M.C. Rhodes J.R. Bucher J.C. Peckham G.E. Kissling M.R. Hejtmancik R.S. Chhabra | 2006 | Food and Chemical Toxicology2006，，5： | 1 |
| 4 | Exposure to antiretroviral therapy in utero or early life: the health of uninfected children born to HIV-infected women显示文摘 | Hankin C Thorne C Peckham C | 2003 | J Acquir Immune Defie Syndr2003，32，4： | 1 |
| 5 | A novel technique in applying skeletal traction for long bone fractures显示文摘 | Al-Khateeb H Peckham T Ibrahim E | 2008 | Ann R Coll Surg Engl2008，90，5： | 1 |
| 6 | The brachioralialis: anatomy, properties, and value for tendon transfer in the tetraplegia显示文摘 | Freehafer AA Peckham PH Keith MW | 1988 | J Hand Surg1988，13，： | 1 |
| 7 | WRF-Chem simulation of East Asian air quality: Sensitivity to temporal and vertical emissions distributions显示文摘 | Xueyuan Wang Xin-Zhong Liang Weimei Jiang Zhining Tao Julian X.L. Wang Hongnian Liu Zhiwei Han Shuyan Liu Yuyan Zhang Georg A. Grell Steven E. Peckham | 2009 | Atmospheric Environment2009，，5： | 1 |
| 8 | Detection of fecal shedding of rotavirus vaccine in infants following their first dose of pentavalent rotavirus vaccine显示文摘 | Catherine Yen Kathleen Jakob Mathew D. Esona Ximara Peckham John Rausch Jennifer J. Hull Susan Whittier Jon R. Gentsch Philip LaRussa | 2011 | Vaccine2011，，24： | 1 |
| 9 | Semantic data models 显示文摘 | Peckham J Maryanski F | 1988 | ACM Computing Survey1988，20，3： | 1 |
| 10 | Comparing ectopic bone growth induced by rhBMP-2 on an absorbable collagen sponge in rat and rabbit models显示文摘 | Hsu HP Zanella JM Peckham SM | 2006 | J Orthop Res2006，24，8： | 1 |
| 11 | Review of meniscal injury and associated sports显示文摘 | Baker BE Peckham AC Pupparo F | 1985 | AmJ Sports Med1985，13，1： | 1 |
| 12 | Clinical and laboratory study of children exposed in utero to maternal rubella显示文摘 | Peckham CS | | 0，，： | 1 |
| 13 | 查看详情显示文摘 | Peckham T Holdcroft S | | 0，，： | 1 |
| 14 | Macrolide antibiotics and cystic fibrosis 显示文摘 | Peckham DG | 2002 | Thorax2002，57，： | 1 |
| 15 | Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells 显示文摘 | Stunz L L Lenert P Peckham D | 2002 | Eur J Immunol2002，32，： | 1 |
| 16 | Atherogenic effect of interleukin-2 and antiatherogenie effect of interleukin-2 antibody in apo-E-deficient mice 显示文摘 | Upadhya S Mooteri S Peckham N | 2004 | Angiology2004，55，3： | 1 |
| 17 | The First Hundred Years of Corn Rei- fining in the United States 显示文摘 | Peckham B W | 2001 | Starch2001，53，6： | 1 |
| 18 | Peripheral nerve stimulation for restoration of motor function显示文摘 | Bhadra N Peckham PH | 1997 | J Clin Neurophysiol1997，14，5： | 1 |
| 19 | An advanced neuroprosthesis for restoration of hand and upper arm control using an implantable controller显示文摘 | Peckham PH Kilgore KL Keith MW | 2002 | J Hand Surg Am2002，27，2： | 1 |
| 20 | Transient tumor marker elevation following chemotherapy for germ cell tumors of the testis显示文摘 | ttorwich A Peckham MJ | 1986 | Cancer Treat Rep1986，70，11： | 1 |
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