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15篇 您的检索式:作者名="Patrick Giraudoux"
    题名 作者 年代 出处 被引量
1高原鼠兔生境选择的初步研究显示文摘在石渠县西区的高山草甸和高山灌丛草甸分布区采用卫星照片(1∶100000)结合样线法,在草地(雅砻江及其支流两边)每隔150m设置一个样方,其他环境则每隔100m设置一个样方,样方面积为5×5m2,记录样方所在地的海拔高度、坡度、坡向、生境位置、样方内植被的盖度、阔叶植物盖度、阔叶植物高度、灌丛盖度、土壤质地、离水源的距离以及鼠兔洞数量.共设置样方312个,样方内的高原鼠兔洞数量最多为80个,最少为0,平均为13.7±15个.统计结果显示:影响高原鼠兔生境选择的主要因子依次是生境位置、土壤质地、离水源的距离、灌丛植物盖度和阔叶植物高度.分析表明,高原鼠兔选择的最优生境为下坡位、土质松软、离水源的距离小于50m、阔叶植物高度小于等于5cm,没有灌丛的环境.王淯 王小明 王正寰 Patrick Giraudoux Kenichi Takahashi Graham Alastair 2004四川大学学报(自然科学版)2004,41,5:37
2Review of risk factors for human echinococcosis prevalence on the Qinghai-Tibet Plateau, China: a prospective for control options显示文摘Objective: Echinococcosis is a major parasitic zoonosis of public health importance in western China. In 2004, the Chinese Ministry of Health estimated that 380,000 people had the disease in the region. The Qinghai-Tibet Plateau is highly co-endemic with both alveolar echinococcosis (AE) and cystic echinococcosis (CE). In the past years, the Chinese government has been increasing the financial support to control the diseases in this region. Therefore, it is very important to identify the significant risk factors of the diseases by reviewing studies done in the region in the past decade to help policymakers design appropriate control strategies. Review: Selection criteria for which literature to review were firstly defined. Medline, CNKI (China National Knowledge Infrastructure), and Google Scholar were systematically searched for literature published between January 2000 and July 2011. Significant risk factors found by single factor and/or multiple factors analysis were listed, counted, and summarized. Literature was examined to check the comparability of the data;age and sex specific prevalence with same data structures were merged and used for further analysis. A variety of assumed social, economical, behavioral, and ecological risk factors were studied on the Plateau. Those most at risk were Tibetan herdsmen, the old and female in particular. By analyzing merged comparable data, it was found that females had a significant higher prevalence, and a positive linearity relationship existed between echinococcosis prevalence and increasing age. In terms of behavioral risk factors, playing with dogs was mostly correlated with CE and/or AE prevalence. In terms of hygiene, employing ground water as the drinking water source was significantly correlated with CE and AE prevalence. For definitive hosts, dog related factors were most frequently identified with prevalence of CE or/and AE;fox was a potential risk factor for AE prevalence only. Overgrazing and deforestation were significant for AE prevalence only. Conclusion: Tibetan herdsmen communities were at the highest risk of echinococcosis prevalence and should be the focus of echinococcosis control. Deworming both owned and stray dogs should be a major measure for controlling echinococcosis;treatment of wild definitive hosts should also be considered for AE endemic areas. Health education activities should be in concert with the local people's education backgrounds and languages in order to be able to improve behaviors. Further researches are needed to clarify the importance of wild hosts for AE/CE prevalence, the extent and range of the impacts of ecologic changes (overgrazing and deforestation) on the AE prevalence, and risk factors in Tibet.Qian Wang Yan Huang Liang Huang Wenjie Yu Wei He Bo Zhong Wei Li Xiangman Zeng Dominique A Vuitton Patrick Giraudoux Philip S Craig Weiping Wu 2014Infectious Diseases of Poverty2014,3,1:35
3Impact of overgrazing on the transmission of Echinococcus multilocularis in Tibetan pastoral communities of Sichuan Province,China显示文摘背景过度放牧被假定增加是包虫 multilocularis 的中间的主人的小哺乳动物的人口密度,在 Qinghai 西藏高原的牙槽的包虫病的病原体。这研究测试了过度放牧可能支持的假设通过增加小哺乳动物的人口的包虫 multilocularis 传播,在擦伤惯例的西藏的牧剧 communities.Methods 的中间的主人,小哺乳动物索引和狗包虫 rnultilocularis 感染数据被收集分析在用的 nonpararnetric 测试和多重逐步的逻辑 regression.Results 过度放牧和包虫 rnultilocularis 传播之间的关系调查一公社的牧场存在,可得到的牧草为放牧是缺乏的。开(普通) 牧场被过度放牧并且与附近的 fenced 相比有小哺乳动物的更高的洞穴密度(私人) 牧场;由附近的 fenced 区域测量的开的牧场上的这个高过度放牧压力在开的牧场导致了小哺乳动物的更高的洞穴密度。在开的牧场的小哺乳动物的中部的洞穴密度独立地与附近犬的包虫 multilocularis 感染被联系(P=0.003, OR=1.048 ) 过度放牧的 .Conclusion 可以通过增加小哺乳动物的人口密度支持包虫 multilocularis 的传播。WANG Qian XIAO Yong-fu Dominique A Vuitton Peter M Schantz Francis Raoul Christine Budke Maiza Campos-Ponce Philip S Craig Patrick Giraudoux 2007Chinese Medical Journal2007,,3:20
4Seasonal pattern of Echinococcus re-infection in owned dogs in Tibetan communities of Sichuan, China and its implications for control显示文摘Background:Human cystic echinococcosis(CE)and alveolar echinococcosis(AE)are highly endemic in Tibetan communities of Sichuan Province.Previous research in the region indicated that domestic dog was the major source of human infection,and observations indicated that domestic dog could have more access to intermediate hosts of Echinococcus spp.:both domestic livestock(CE)viscera and small mammals(AE),in early winter and again in spring.We hypothesized that there would therefore be a significant increase in the risk of canine infection with Echinococcus spp.in these two seasons and conducted a reinfection study to investigate this further.Methods:Faecal samples were collected from owned dogs in seven townships in Ganze Tibetan Autonomous Prefecture(Sichuan Province,China),and Echinococcus spp.infection status was determined using copro-antigen ELISA.Dogs were sampled in April(spring),July(early summer),September/October(autumn/early winter)and December(winter)in 2009;and in April(spring)2010.Dogs were treated with praziquantel following each of the five sample collections to eliminate any tapeworms.Information on dog sex,age and body weight was also collected.The t-test,Fisher’s exact test,Poisson regression and logistic regression were used to compare means and prevalences,and to identify factors associated with infection status.Results:The proportion of female dogs was significantly lower than that of male dogs;female dogs had significantly higher(22.78%)baseline copro-ELISA prevalence than males(11.88%).Dog body weight,sex,age,county and previous infection status at any sampling point had no influence on the re-infection prevalence in general.Poisson regression did not found a significant influence on the re-infection prevalence due to different deworming/sampling time spans.Dogs exhibited significantly higher re-infection prevalences in spring and early summer of 2009 and in early winter between September/October and December of 2009,suggesting a higher infection pressure in these seasons comparing with other seasons.Conclusion:Following praziquantel treatment,dog body weight,sex,age,county,deworming time span and previous infection status at any sampling point had no influence on the re-infection prevalence in the region in general.The differences between re-infection prevalences were probably due to the seasonality in Echinoccocus spp.infection pressure in the region.Early winter,spring and early summer should be important seasons for optimal dog deworming intervention in these Tibetan communities.Qian Wang Wen-Jie Yu Bo Zhong Jing-Ye Shang Liang Huang Alexander Mastin Renqingpengcuo Yan Huang Guang-Jia Zhang Wei He Patrick Giraudoux Wei-Ping Wu Philip S.Craig 2016Infectious Diseases of Poverty2016,5,1:15
5Grass height and transmission ecology of Echinococcus multilocularis in Tibetan communities, China显示文摘背景牙槽的包虫病是在西方的中国的公共健康意义的主要动物病。过度放牧最近为牙槽的包虫病的传播作为一个潜在的风险因素被假定。研究被设计进一步由调查过度放牧怎么影响了中间的主人的洞穴密度测试过度放牧的假设小哺乳动物并且小哺乳动物的洞穴密度怎么与狗包虫 multilocularis infection.Methods 被联系学习地点被发现了牙槽的包虫病是流行的区域的以前的研究选择。数据包括草高度,挖中间的主人的密度烘便的样品以及全球放系统(GPS ) 放的小哺乳动物,狗和狐狸,在 Shiqu 县从领域调查被收集,四川省,中国。烘便的样品用 copro-PCR 被分析。在烘便的样品的蠕虫,牙齿,骨头和头发视觉上被检验。包括 chi 平方和概括线性模型的单个因素和 multifactor 分析工具被把草高度用作在同质的牧场擦伤压力的一个代理用于这些 data.Results ,在导致的牧场发现那棵更高的草的这研究降低小哺乳动物的洞穴密度 X^2=A.67O , P=0.031 , coefficient=-1.570 )。在狗的包虫 multilocularis 蠕虫负担是显著地统计上与中介的最大的密度有关招待 Ochotona spp。(X^2=5.250, P=0.022, coefficient=0.028 ) 。在拥有的狗的流行断然被相关到在 200 米半径以内看见的迷路的狗的数字(Wald X^2=8.375, P=0.004,机会 ratio=1.198 ) 。结论我们的调查结果支持过度放牧支持的假设牙槽的包虫病的传播并且在牙槽的包虫病的传播证实迷路的狗的角色。WANG Qian Francis Raoul Christine Budke Philip S. Craig XIAO Yong-fu, Dominique A. Vuitton,Maiza Campos-Ponce, QIU Dong-chuan, David Pleydell and Patrick Giraudoux XIAO Yong-fu Dominique A. Vuitton Maiza Campos-Ponce QIU Dong-chuan David Pleydell Patrick Giraudoux 2010Chinese Medical Journal2010,,1:12
6四川西部石渠地区夏季藏狐巢穴选择的生境分析显示文摘通过对四川石渠地区夏季藏狐洞穴生境选择的研究 ,以水源距离、洞口朝向、坡向、坡度、坡位、植被类型及鼠兔和鼠类洞穴等 7项指标为变量 ,运用主成分分析和聚类分析相结合的方法对收集到的 5 4个藏狐洞穴样本进行了分析。主成分分析在 4个主成分下达到 85 %的显著性。在第一主成分中水源距离、坡度和坡位是重要的影响变量 ,在另外 3个主成分中鼠类洞穴数量以及植被类型两变量也非常重要。聚类分析显示 ,5 4个洞穴样本在 3个水平上聚成 5类。藏狐易于选择草甸地带 ,中缓坡和低坡位 ,坡向多为阳坡或半阳坡 ,水源距离小于5 0 0m的地方筑巢 ,其穴口朝向多位于 135°~ 36 0°之间。此外 ,鼠兔和鼠类洞穴在藏狐洞穴样方内的出现 ,但数量变异较大 ,揭示小型哺乳动物和藏狐之间可能存在着复杂的相互关系。通过对四川石渠地区夏季藏狐洞穴生境选择的研究 ,以水源距离、洞口朝向、坡向、坡度、坡位、植被类型及鼠兔和鼠类洞穴等 7项指标为变量 ,运用主成分分析和聚类分析相结合的方法对收集到的 5 4个藏狐洞穴样本进行了分析。主成分分析在 4个主成分下达到 85 %的显著性。在第一主成分中水源距离、坡度和坡位是重要的影响变量 ,在另外 3个主成分中鼠类洞穴数量以及植被类型两变量也非常重要。聚类分析显示 ,5王正寰 王小明 吴巍 Patrick Giraudoux 邱加闽 高桥健一 Philip S Crai 2003兽类学报2003,23,1:10
7包虫病手术患者1312例流行病学资料分析显示文摘目的了解青藏高原包虫病的分布特点。方法对1992-2006年的1312例包虫病手术患者的相关资料进行分析。结果囊型和泡型包虫病均有分布。患者主要集中于21~50岁,20岁以下的患者相对较少,以藏族为主。囊型包虫病分布于四川省甘孜州和阿坝州的17个县以及青海省果洛州的5个县,而泡型包虫病同时分布于其中的大部分地区。结论囊型和泡型包虫病同时流行于四川省的西北部和青海省的东南部。仁真 李调英 廖万明 陈兴旺 赵晓东 肖宁 喻晓慧 张西春 Akira Ito 邱加闽 Patrick Giraudoux Philip S Craig 2008寄生虫病与感染性疾病2008,6,3:8
8Priorities for research and control of cestode zoonoses in Asia显示文摘Globally,cestode zoonoses cause serious public health problems,particularly in Asia.Among all neglected zoonotic diseases,cestode zoonoses account for over 75%of global disability adjusted life years(DALYs)lost.An international symposium on cestode zoonoses research and control was held in Shanghai,China between 28th and 30th October 2012 in order to establish joint efforts to study and research effective approaches to control these zoonoses.It brought together 96 scientists from the Asian region and beyond to exchange ideas,report on progress,make a gap analysis,and distill prioritizing settings with a focus on the Asian region.Key objectives of this international symposium were to agree on solutions to accelerate progress towards decreasing transmission,and human mortality and morbidity caused by the three major cestode zoonoses(cystic echinococcosis,alveolar echinococcosis,and cysticercosis);to critically assess the potential to control these diseases;to establish a research and validation agenda on existing and new approaches;and to report on novel tools for the study and control of cestode zoonoses.Ning Xiao Jia-Wen Yao Wei Ding Patrick Giraudoux Philip S Craig Akira Ito 2013Infectious Diseases of Poverty2013,2,1:6
9A historical view of alveolar echinococcosis, 160 years after the discovery of the first case in humans: part 1. What have we learnt on the distribution of the disease and on its parasitic agent?显示文摘自从著名科学家鲁道夫·弗乔在 1855 在疾病的起源在南部的德国和一个寄生虫的正确鉴定观察的开始的 2 个盒子,牙槽的包虫病(AE ) 的地方性的区域的边阶从来没停下来过膨胀。寄生虫连续地在瑞士被认出,然后为疾病在长的俄国,奥地利和法国考虑了同样唯一的地方性的区域。盒子在 1939 在土耳其被揭示;然后,许多注意对阿拉斯加并且到北海道被给予,在日本。状况完全由科学家的国际社区在中国地方性的区域的识别以后在 1991 变化了。世界地图被 AE 的鉴定,并且由盒子的识别在中亚在大多数中央 / 东方的欧洲和波罗的语州的国家在第 21 世纪的开始完成。直到现在,疾病从来然而没在南方半球并且在英国被报导过。在 mid-1950s ,由在阿拉斯加的 Rausch 和德国诗人,并且由在德国的 Vogel 的示范,在 2 寄生虫种类之间的区别负责分别地为膀胱的包虫病(“胞虫疾病”)和 AE 结束在“二元论者”之间的长持续的争论,谁相信了那最后证明了真的理论,和“ unicists ”,相信了为两疾病负责的单个种。在第 20 世纪的结束,分子的生物学充分证实了“二元论者”理论当把几新种加到开始描述的 E 时。granulosus;在过去的十年以内,它也证实很少变化在西藏的高原上在一些中间的动物宿主在包虫(E.) multilocularis 种类,和那 AE-Iooking 感染以内存在确实由于新种,从 E 不同。multilocularis,命名 E。shiquicus。自从 1970 年代,在风景之间的唯一的生态的相互作用,主人,和 E。multilocu/aris 日益增多地被描出。为寄生虫周期的维护的啮齿类动物 / 兔类动物水库尺寸的重要角色在第 20 世纪的最后 2 十年以内被认出了。并且在在由农业 / 林地的陆地使用的小哺乳动物和个性的高密度之间的一种靠近的关系的发现在污染压力上强调了政治 / 经济的决定的责任。在欧洲和日本和在中国的狗的主要角色的狐狸的都市化关于权威的主人和预防措施在 21 st 世纪的开始代表新买卖。Dominique Angele Vuitton WANG Qian ZHOU Hong-xia Francis Raoul Jenny Knapp Solange Bresson-Hadni WEN Hao Patrick Giraudoux 2011Chinese Medical Journal2011,,18:5
10The landscape epidemiology of echinococcoses显示文摘Echinococcoses are parasitic diseases of major public health importance globally.Human infection results in chronic disease with poor prognosis and serious medical,social and economic consequences for vulnerable populations.According to recent estimates,the geographical distribution of Echinococcus spp.infections is expanding and becoming an emerging and re-emerging problem in several regions of the world.Echinococcosis endemicity is geographically heterogeneous and over time it may be affected by global environmental change.Therefore,landscape epidemiology offers a unique opportunity to quantify and predict the ecological risk of infection at multiple spatial and temporal scales.Here,we review the most relevant environmental sources of spatial variation in human echinococcosis risk,and describe the potential applications of landscape epidemiological studies to characterise the current patterns of parasite transmission across natural and human-altered landscapes.We advocate future work promoting the use of this approach as a support tool for decision-making that facilitates the design,implementation and monitoring of spatially targeted interventions to reduce the burden of human echinococcoses in disease-endemic areas.Angela M.Cadavid Restrepo Yu Rong Yang Donald P.McManus Darren J.Gray Patrick Giraudoux Tamsin S.Barnes Gail M.Williams Ricardo J.Soares Magalhães Nicholas A.S.Hamm Archie C.A.Clements 2016Infectious Diseases of Poverty2016,5,1:2
11中国中部寄生虫病的景观控制(英文)显示文摘多房棘球绦虫(Echinococcus multilocularis)的幼虫期导致罕见而致命的肝病即人类的泡型包虫病(HAE)。绦虫在狐狸(或狗类)与一些小型哺乳类动物之间以寄生虫-寄主的方式进行循环传播。中国中部一些地区的人类泡型包虫病属于地方流行病,在部分乡村的发生概率达到15%。本文研究如何利用遥感数据并基于地区景观特性获取该流行病清晰地空间危害分布图。遥感数据分析的结果显示,人类居住地附近的草地或灌木是HAE传播的一个主要危险区域,从空间分布上看,这些区域是小型哺乳动物等中间寄主的聚集处。F. Mark Danson Patrick Giraudoux David Pleydell Philip S. Craig 2007遥感学报2007,11,5:2
12Morphological and molecular characteristics of Echinococcus multilocularis and Echinococcus granulosus mixed infection in a dog from Xinjiang, China显示文摘Zhang YL Jean-Mathieu Bart Patrick Giraudoux 2006Vet Parasitol2006,139,:1
13Genetic polymorphisms of Echinococcus tapeworms in China as determined by mitochondrial and nuclear DNA sequences显示文摘Minoru Nakao Tiaoying Li Xiumin Han Xiumin Ma Ning Xiao Jiamin Qiu Hu Wang Tetsuya Yanagida Wulamu Mamuti Hao Wen Pedro L. Moro Patrick Giraudoux Philip S. Craig Akira Ito 2009International Journal for Parasitology2009,,3:1
14Echinococcosis in Ningxia Hui Autonomous Region, northwest China显示文摘Yu Rong Yang Philip S. Craig Tao Sun Dominique A. Vuitton Patrick Giraudoux Malcolm K. Jones Gail M. Williams Donald P. McManus 2008Transactions of the Royal Society of Tropical Medicine and Hygiene2008,,4:1
15Transmission ecology of Echinococcus multilocularis : What are the ranges of parasite stability among various host communities in China?显示文摘Patrick Giraudoux David Pleydell Francis Raoul Jean-Pierre Quéré Qian Wang Yurong Yang Dominique A. Vuitton Jiamen Qiu Wen Yang Philip S. Craig 2005Parasitology International2005,,:1
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