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| 1 | Silent diabetic nephropathy显示文摘AIM: To examine the risk of renal events in patients with biopsy-proven diabetic nephropathy(DN) and its possible associated factors.METHODS: Clinical and histological data of 60 patients diagnosed with diabetic nephropathy were retrospectively collected. Patients with evidence or suspicion of other nephropathies were excluded from the study. The final event was defined as renal replacement therapy(RRT) initiation or progression of chronic kidney disease(CKD), according to the KDIGO 2012 definition of a decrease in CKD category and a decrease in GFR of 25% or more. RESULTS: A total of 45 patients with a follow-up of at least 3 mo were included. Most of the patients presented type 2 DM, with a median age of 58.3 years old. The time of evolution of DM was 9.6 ± 7.8 years, although in 13 patients, it was less than 5 years. A total of 62% of patients reached the final event in a mean period of 3.4 years(95%CI: 2.1-4.7), with 21 of them requiring dialysis. The factors that were independently associated with renal survival were estimated glomerular filtration rate(e GFR) at the time of biopsy, cardiovascular disease(CVD) history and Hb A1 c less than 7%. Therefore, for each 10 m L/min per 1.73 m2 reduction in e GFR, we obtained a DN progression risk of HR = 2(1.3-3.0)(P = 0.001); patients with CVD were at greater risk for DN progression(HR = 2.8, 1.1-7.1, P = 0.032), and CKD patients with Hb A1 c < 7% demonstrated greater renal risk than patients with Hb A1 c ≥ 7%, with an HR of 2.9(1.0-8.4)(P = 0.054).CONCLUSION: A past history of CVD is a risk factor for DN progression. Levels of Hb A1 c less than 7% could favor an e GFR decrease in these patients. | Katia López-Revuelta Patricia Pea Galdo Ramona Stanescu Leticia Parejo Carmen Guerrero Elia Pérez-Fernández | 2014 | World Journal of Nephrology2014，3，1： | 2 |
| 2 | Comparison between the radical scavenging activity and antioxidant activity of six distilled and nondistilled Mediterranean herbs and aromatic plants 显示文摘 | Parejo I Viladomat F Bastida J | 2002 | J Agric Food Chem2002，50，： | 1 |
| 3 | Gabapentin in the treatment of ocular neuromyotonia显示文摘 | Porta Etessam J Parejo Carbonell B Gomez-Vicente L | 2009 | Rev Neurol2009，48，： | 1 |
| 4 | Do avian brood parasites eavesdrop on heterospecific sexual signals revealing host quality? A review of the evidence显示文摘 | Parejo D Avilés JM | | 0，，： | 1 |
| 5 | Small Firms, R&D, Technology and Innovation in The UK:A Literature Review 显示文摘 | Hoffman K Parejo M Bessant J | 1998 | Technovation1998，18，1： | 1 |
| 6 | Risk factors for intubation as a guide for noninvasive ventilation in patients with severe acute cardiogenic pulmonary edema显示文摘 | Josep Masip Joaquim Páez Montserrat Merino Sandra Parejo Francisco Vecilla Clara Riera Araceli Ríos Joan Sabater Josep Ballús J. Padró | 2003 | Intensive Care Medicine2003，，11： | 1 |
| 7 | Effect of anti - CD14 antibody on clearance of Escherichia coli bacteremia and endotox- emia显示文摘 | Opal SM Palardy JE Parejo N | 2003 | Crit Care Med2003，31，3： | 1 |
| 8 | Photostability and re- tention of UV absorber molecules in sol-gel hybrid UV- protective coatings 显示文摘 | PAREJO P G ZAYAT M LEVY D | 2010 | Journal of Sol- Gel Science and Technolgy2010，，53： | 1 |
| 9 | Small Firms, R&D, Technology and Innovation in the UK: a literature Review 显示文摘 | Kurt Hoffman Milady Parejo John Bessant and LOw Perren | 1998 | Technovation1998，18，01： | 1 |
| 10 | Evaluation of scavenging activity assessed by Co (II)/EDTA- in- duced luminol chemiluminescence and DPPH (2, 2 - di- phenyl - 1 - pierylhydrazyl) free radical assay 显示文摘 | PAREJO I CODINA C PETRAKIS C | 2000 | Jour- nal of Pharmacological and Toxicological Methods2000，44，3： | 1 |
| 11 | The activity of tissue factor pathway inhibitor in experimental models of super antigen-induced shock and polymicrobial intra-abdominal sepsis 显示文摘 | Opal S M Palardy J E Parejo N A | 2001 | Crit Care Med2001，29，1： | 1 |
| 12 | Acylated quercetagetin glycosides with antioxidant activity from Tagetes maxima显示文摘 | PAREJO I BASTIDA J VILADOMAT F | 2005 | Phytochemistry2005，66，： | 1 |
| 13 | Photostability and retention of UV absorber molecules in sol-gel hybrid UV-protective coatings显示文摘 | Parejo P G Zayat M Levy D | 2010 | J Sol-Gel Sci Technol2010，，53： | 1 |
| 14 | Evaluation of scavenging activity assessed by Co(Ⅱ)/EDTA-induced luminal chemiluminescence and DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical assay显示文摘 | Parejo I Codina C Petrakis C | 2000 | Journal Pharmacol Toxicol2000，44，： | 1 |
| 15 | The activity of tissue factor pathway inhibitor in experimental models of superantigen-induced shock and polymicrobial intra-abdominal sepsis显示文摘 | Opal SM Palardy JE Parejo NA | 2001 | Crit Care Med2001，29，1： | 1 |
| 16 | Evaluation of scavenging activity assessed by Co (II)/EDTA-induced luminal chemiluminescence and DPPH free radical assay显示文摘 | Parejo I Codina C Petrakis C | 2000 | Journal Pharmacol Toxicol2000，44，： | 1 |
| 17 | Evaluation of scavenging activity assessed by Co(II)/EDTA-induced luminol chemiluminescence and DPPH free radical assay显示文摘 | Parejo I Codina C Petrakis C | 2000 | J Phannacol Tomcd Methods2000，44，3： | 1 |
| 18 | Acylated quercetagetin glycosides with antioxidant activity from Tagetes maxima显示文摘 | Irene Parejo Jaume Bastida Francesc Viladomat Carles Codina | 2005 | Phytochemistry2005，，19： | 1 |
| 19 | Evaluation of scaven ging activity assessed by Co(II)/EDTA-induced luminal chem iluminescence and DPIH free radical assay显示文摘 | Parejo I Codina C Petrakis C | 2000 | Journal Phar macol Toxicol2000，44，： | 1 |
| 20 | Evaluation of scavenging activity assessed by Co(Ⅱ)/EDTA-induced luminol chemiluminescence and DPPH(2,2-diphenyl-1-picrylhydrazyl) free radical assay显示文摘 | Parejo I Petrakis C Kefalas C | 2000 | Journal of Pharmacological and Toxicological Methods2000，44，3： | 1 |
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