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24篇 您的检索式：作者名="Pan SP"

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	题名	作者	年代	出处	被引量
1	Characterization of cancer genomic heterogeneity by next-generation sequencing advances precision medicine in cancer treatment显示文摘Cancer is a heterogeneous disease with unique genomic and phenotypic features that differ between individual patients and even among individual tumor regions.In recent years,large-scale genomic studies and new next-generation sequencing technologies have uncovered more scientifc details about tumor heterogeneity,with significant implications for the choice of specific molecular biomarkers and clinical decision making Genomic heterogeneity signifcantly contributes to the generation of a diverse cell population during tumor development and progression,representing a determining factor for variation in tumor treatment response.It has been considered a prominent contributor to therapeutic failure,and increases the likelihood of resistance to future therapies in most common cancers.The understanding of molecular heterogeneity in cancer is a fundamental component of precision oncology,enabling the identification of genomic alteration of key genes and pathways that can be targeted therapeutically.Here,we review the emerging knowledge of tumor genomics and heterogeneity,as well as potential implications for precision medicine in cancer treatment and new therapeutic discoveries.An analysis and interpretation of the TCGA database was included.	Jialing Zhang Stephan Stanislaw Späth Sadie L.Marjani Wengeng Zhang Xinghua Pan	2018	Precision Clinical Medicine2018，1，1：	5
2	Infertility and testicular defects in hormone-sensitive lipase-deficient mice显示文摘	Chung S Wang SP Pan L	2001	Endocrinology2001，142，10：	1
3	Folbp1 promotes embryonic myocardial cell proliferation and apoptosis through the WNT signal transduction pathway显示文摘	Han SP Pan Y Peng YZ		0，，03：	1
4	Folbpl promotes embryonic myocardial cell proliferation and apoptosis through the WNT signal transduction pathway显示文摘	Hart SP Pan Y Peng YZ	2009	lnt J Mol Med2009，23，3：	1
5	Interleukin 6 promoter polymorphisms in normal Han Chinese population: frequencies and effects on inflammatory markers 显示文摘	Pan M Gao SP Jiang MH	2011	Investig Med2011，59，2：	1
6	显示文摘	Li X Jiang B Pan B: Biotranstbrmation of phenylpyruvic acid to phenyllactic acid by growing and resting cells of a Lactobacillus sp	2007	Biotechnol Lett2007，29，：	1
7	Interleukin 6 promoter polymorphisms in normal Han Chinese population:fre- quencies and effects on inflammatory markers显示文摘	Pan M Gao SP Jiang MH	2011	J In- vestig Med2011，59，2：	1
8	Preparation of chitosanplasmid DNA nanoparticles encoding zona pellucida glycoprotein-3alpha and its expression in mouse显示文摘	Sun CJ Pan SP Xie QX	2004	Mol Reprod Dev2004，68，：	1
9	Properties and amino acid sequence of Huwentoxin-1, a neurotoxin purified from the venom of the Chinese bird spider Ornithoctonus Huwena显示文摘	Liang SP Zhang DY Pan X	1993	Toxicon1993，31，8：	1
10	Clinical significance of serum Hcyand hs-CRP testing before and after the treatment of patients withacute cerebral infarction显示文摘	Zang ZZ Pan SY Xu SP	2007	Radiat J Immunol2007，20，5：	1
11	Combination of cyclooxygenase-2 inhibitor and doxorubicin increases the growth inhibition and apoptosis in human hepatocellular carcinoma cells显示文摘	Pan YY Xu SP Jia XY	2007	Exp Oncol2007，29，1：	1
12	Interleukin 6 promoter polymorphisms in normal han chinese population: frequencies and effects on inflannnatory markers 显示文摘	Pan M Gao SP Jiang MH	2011	J Investig Med2011，59，2：	1
13	Interleukin-6 promoter polymorphisms in normal han chinese population:frequencies and effects on inflammatory markers显示文摘	Pan M Gao SP Jiang MH		0，，2：	1
14	Is inflammation linked to thrombogenesis inatrial fibrillation显示文摘	Gao SP Deng XT Ge LJ Luan H Zheng JG Chen C Jiang MH Pan M	2011	Int J Cardiol2011，149，：	1
15	The Association of Interleukin 6-634C/G polymorphism with left atrial thrombus and severe spontaneous echo contrast in patients with atrial fibrillation显示文摘	Deng XT Jiang MIq Zhu JH Ge LJ Guo J Gao SP Zheng JG Luan H Shi GL Wang RX Shi HF Pan M	2013	Clin Appl Thromb Hemost2013，19，：	1
16	Is inflammation linked to thrombogenesis inatrial fibrillation显示文摘	Gao SP Deng XT Ge LJ Luan H Zheng JG Chen C Jiang MH Pan M	2011	Int J Cardiol2011，149，：	1
17	The Association of Interleukin 6-634C/G polymorphism with left atrial thrombus and severe spontaneous echo contrast in patients with atrial fibrillation显示文摘	Deng XT Jiang MIq Zhu JH Ge LJ Guo J Gao SP Zheng JG Luan H Shi GL Wang RX Shi HF Pan M	2013	Clin Appl Thromb Hemost2013，19，：	1
18	Osteoprotective effect of Monascus-fer-mented dioscorea in ovariectomized rat model of postmenopausal osteo-porosis显示文摘	Chiang SS Chang SP Pan TM	2011	J Agric Food Chem2011，59，17：	1
19	Grazing alters ecosystem functioning and C:N:P stoichiometry of grasslands along a regional precipitation gradient显示文摘	Bai YF Wu JG Clark CM Pan QM Zhang LX Chen SP Wang QB Han XG		0，，：	1
20	Preparation of chitosan- plasmid DNA nanoparticles encoding zona pellucida gly- co-protein-aalpha and its expression in mouse显示文摘	Sun CJ Pan SP Xie QX	2004	Mol Reprod Dev2004，68，2：	1

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