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| 1 | Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma显示文摘 | Andrew D. Rhim Paul E. Oberstein Dafydd H. Thomas Emily T. Mirek Carmine F. Palermo Stephen A. Sastra Erin N. Dekleva Tyler Saunders Claudia P. Becerra Ian W. Tattersall C. Benedikt Westphalen Jan Kitajewski Maite G. Fernandez-Barrena Martin E. Fernandez- | 2014 | Cancer Cell2014,,: | 5 |
| 2 | Pioneering drugs for overactive bladder and detrusor overactivity: Ongoing research and future directions显示文摘The ongoing research on pioneering drug candidates for the overactive bladder(OAB) aimed to overcome the limitations of currently licensed pharmacotherapies, such as antimuscarinics, β3-adrenergic agents, and botulinum neurotoxin, has been reviewed performing a systematic literature review and web search. The review covers the exploratory agents alternative to available medications for OAB and that may ultimately prove to be therapeutically useful in the future management of OAB patients based on preclinical and early clinical data. It emerges that many alternative pharmacological strategies have been discovered or are under investigation in disease-oriented studies. Several potential therapeutics are known for years but still find obstacles to pass the clinical stages of development, while other completely novel compounds, targeting new pharmacological targets, have been recently discovered and show potential to translate into clinical therapeutic agents for idiopathic and neurogenic OAB syndrome. The global scenario of investigational drugs for OAB gives promise for the development of innovative therapeutics that may ultimately prove effective as first, combined or second-line treatments within a realistic timescale of ten years. | Emilio Sacco Salvatore Recupero Riccardo Bientinesi Giuseppe Palermo Daniele D'Agostino Diego Currò Pierfrancesco Bassi | 2015 | World Journal of Obstetrics and Gynecology2015,4,2: | 3 |
| 3 | Differential expression of the fractalkine chemokine receptor (CX3CR 1) in human rnonocytes during differentiation显示文摘传播单核白血球(瞬间) 可以连续地使人重新住入巨噬细胞(MAC ) 或树枝状的房间(DC ) 维持动态平衡的人口。MAC 和 DC 是玩不同、互补的免疫学的功能的专业化房间。因此,他们现在的不同迁移的性质。明确地,而 MAC 大部分留在纸巾, DC 能够从外部纸巾移居到淋巴的机关。这个工作的目的是分析 fractalkine 受体的表达式(CX 3 CR1 ) 在 monocytic 区别进程期间。两 CX 3 CR1 mRNA 和蛋白质。在瞬间区别过程期间, CX 3 CR1 是在 DC 和 MAC 的 downregulated。然而, MAC 显示出显著地更高的 CX 3 CR1 表示层次比 DC。我们也观察了对抗 CX 3 由干扰素(IFN ) 的 CR1 规定 -γ并且 interleukin (IL )-4 在通过古典、其他的 MAC 小径的 MAC 激活期间分别地。IFN-γ禁止了 CX 3 CR1,而是 IL-4 导致了它。另外,我们表明了在 CX 3 由可溶的 fractalkine 的 CR1 表示和 apoptosis 预防(sCX 3 CL1 ) 在瞬间, DC 和 MAC。这是表明顺序、微分的 CX 3 CR1 调整在瞬间区别期间。最重要地,我们表明了在 CX 3 CR1 表示和房间幸存面对 sCX 3 CL1。 | Cecilia Analia Panek Maria Victoria Ramos Maria Pilar Mejias Maria Iimena Abrey-Recalde Romina Iimena Fernandez-Brando Maria Soledad Gori Gabriela Veronica Salamone2 Marina Sandra Palermo | 2015 | Cellular & Molecular Immunology2015,12,6: | 3 |
| 4 | The August 14, 2003 blackout andits importance to China显示文摘本文作者P .JeffreyPaleimo先生系美国KEMA公司的资深电力专家 ,2 0 0 4年 1月在上海就美加8·14大停电事故及中国电网的安全运行同我国同行进行了交流、探讨。首篇刊出特邀P JeffreyPaleimo就8·14美加大停电原因、涉及的电力体制以及中国和亚洲的电力市场应引以为鉴作了专题论述。结合美国国内的各新闻报道和评论 ,以美加大停电特别工作小组的中期报告作为依据 ,归纳了大停电发生的原因 ,特别指出美国现行电力体制中出现的对长距离输电时的地区由于协调控制薄弱 ,增加了发生大停电的可能性。指出 ,在中国东部地区 ,国民经济每年以 10 %以上的速度发展 ,对电力系统发展具有很高的要求是必然的 ,因而对现有电力系统要不断重新评估分析 ,设计中要考虑隔离点 (breakpoints) ,保证必要时以孤岛模式运行。 | By P. Jeffrey Palermo | 2004 | 华东电力2004,32,1: | 2 |
| 5 | Seismic performance of non-structural components and contents in buildings: an overview of NZ research显示文摘This paper summarizes the research on non-structural elements and building contents being conducted at University of Canterbury in New Zealand.Since the 2010-2011 series of Canterbury earthquakes,in which damage to non-structural components and contents contributed heavily to downtime and overall financial loss,attention to seismic performance and design of non-structural components and contents in buildings has increased exponentially in NZ.This has resulted in an increased allocation of resources to research leading to development of more resilient non-structural systems in buildings that would incur substantially less damage and cause little downtime during earthquakes.In the last few years,NZ researchers have made important developments in understanding and improving the seismic performance of secondary building elements such as partitions,facades,ceilings and contents. | Rajesh P Dhakal Atefeh Pourali Ali Sahin Tasligedik Trevor Yeow Andrew Baird Gregory Mac Rae Stefano Pampanin Alessandro Palermo | 2016 | Earthquake Engineering and Engineering Vibration2016,15,1: | 2 |
| 6 | Fertiliza- tion and pregnancy outcome with intracytoplasmic sperm injection for azoospermic men显示文摘 | Palermo GD Schlegel PN Hariprashad J J | 1999 | Hum Reprod1999,14,3: | 1 |
| 7 | Pseudorabies virus as a live vector for expression of foreign genes 显示文摘 | THOMEN D R MAROTTI K R PALERMO D P | 1987 | Gene1987,57,23: | 1 |
| 8 | Gene expres- sion study of two widely used pig intestinal epithelial cell lines: IPEC-J2 and IPI-2I显示文摘 | Mariani V Palermo S Fiorentini S | 2009 | Vet Immunol Im- munopathol2009,131,4: | 1 |
| 9 | Assisted reproductive technologies and monozygous twins:implications for future study and clinical practice显示文摘 | Sills ES Tucker MJ Palermo GD | 2000 | Twin Res2000,3,: | 1 |
| 10 | uCyt+/ImmunoCyt and cytology in the detection of urothelial carcinoma:an update on 7422 analyses显示文摘 | Comploj E Mian C Ambrosini-Spaltro A Dechet C Palermo S Trenti E | | 0,,: | 1 |
| 11 | Evaluation of the efficacy of propionyl-L-carnitine versus pulsed muscular compressions in diabetic and non-diabetic patients affected by obliterating arteriopathy Leriehe stage Ⅱ显示文摘 | Riccioni C Sarcinella R Palermo G | 2008 | Int Angiol2008,27,3: | 1 |
| 12 | Concomitant gonadotropin-releasing hormone agonist and menotropin treatment for the synchronized induction of multiple follicles显示文摘 | Palermo R Amodeo G Navot D | 1988 | Fertil Steril1988,49,2: | 1 |
| 13 | Concept and development of hybrid systems for seismic-resistant bridges 显示文摘 | Palermo A Pampanin S Calvi G | 2005 | Journal of Earthquake Engineering2005,9,6: | 1 |
| 14 | East and accurate timing characterization using functional information显示文摘 | YALCIN H MORTAZAVI M PALERMO R C | 2000 | IEEE Trans CAD2000,20,2: | 1 |
| 15 | Pseudorabies virus as a live vector for expression of foreign genes显示文摘 | Thomsen D R Marotti K R Palermo D P | 1987 | Geae1987,57,: | 1 |
| 16 | Design considerations for in-situ capping of contaminated sediments显示文摘 | Palermo Michael R | 1998 | Water Science and Technology1998,37,67: | 1 |
| 17 | Cutting edge:recombinase-activating gene expression and V(D)J recombination in CD4+CD3low mature T lymphocytes显示文摘 | Lantelme E Palermo B Granziero L | 2000 | J Immunol2000,164,7: | 1 |
| 18 | Laparoscopic Whipple procedure:review of the literature显示文摘 | Gagner M Palermo M | 2009 | J Hepatobiliary Pancreat Surg2009,16,6: | 1 |
| 19 | Cytogenetie evalua- tion of two nitroimidazole derivatives显示文摘 | Lopez NMM Palermo AM Mudry MD | 2003 | Toxicol In Vitro2003,17,1: | 1 |
| 20 | Self-assembly of π-conjugated discs on heterogeneous surfaces:Effect of the micro-and nano-scale dewetting显示文摘 | Palermo V Palma M Tomov(ic) (Z) | | 0,,1: | 1 |