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449篇 您的检索式:作者名="Paganelli"
    题名 作者 年代 出处 被引量
1P2Y12-ADP receptor antagonists: Days of future and past显示文摘Antiplatelet therapy is the cornerstone of the therapeutic arsenal in coronary artery disease.Thanks to a better understanding in physiology,pharmacology and pharmacogenomics huge progress were made in the field of platelet reactivity inhibition thus allowing theexpansion of percutaneous coronary intervention.Stent implantation requires the combination of two antiplatelet agents acting in a synergistic way.Asprin inhibit the cyclo-oxygenase pathway of platelet activation while clopidogrel is a P2Y12 adenosine diphosphate(ADP)-receptor antagonist.This dual antiplatelet therapy has dramatically improved the prognosis of stented patients.However,due to pharmacological limitations of clopidogrel(interindividual variability in its biological efficacy,slow onset of action,mild platelet reactivity inhibition)ischemic recurrences remained high following stent implantation especially in acute coronary syndrome patients.Thus,more potent P2Y12-ADP receptor inhibitors were developped including prasugrel,ticagrelor and more recently cangrelor to overcome these pitfalls.These new agents reduced the rate of thrombotic events in acute coronary syndrome patients at the cost of an increased bleeding risk.The abundance in antiplatelet agents allow us to tailor our strategy based on the thrombotic/bleeding profile of each patient.Recently,the ACCOAST trial cast a doubt on the benefit of pre treatment in non-ST segment elevation acute coronary syndrome.The aim of the present review is to summarize the results of the main studies dealing with antiplatelet therapy in stented/acute coronary syndromes patients.Marc Laine Franck Paganelli Laurent Bonello 2016World Journal of Cardiology2016,8,5:4
2Chronic hepatitis B in children and adolescents显示文摘Massimiliano Paganelli Xavier Stephenne Etienne M. Sokal 2012Journal of Hepatology2012,,4:3
3Management of chronic hepatitis B in childhood: ESPGHAN clinical practice guidelines显示文摘Etienne M. Sokal Massimiliano Paganelli Stefan Wirth Piotr Socha Pietro Vajro Florence Lacaille Deirdre Kelly Giorgina Mieli-Vergani 2013Journal of Hepatology2013,,:3
4Sustained neuroprotection and facilitation of behavioral recovery by the Ginkgo biloba extract, EGb 761, after transient forebrain ischemia in rats显示文摘Ricardo Alexandre Paganelli Arcelio Benetoli Humberto Milani 2006Behavioural Brain Research2006,,:2
5Hilar Cholangiocarcinoma: Preoperative Liver Optimization with Multidisciplinary Approach. Toward a Better Outcome显示文摘Francesca Ratti Federica Cipriani Fabio Ferla Marco Catena Michele Paganelli Luca A. M. Aldrighetti 2013World Journal of Surgery2013,,6:2
6Overexpression of microRNA-145 in atherosclerotic plaques from hypertensive patients显示文摘Donato Santovito Claudia Mandolini Pamela Marcantonio Velia De Nardis Marco Bucci Camilla Paganelli Francesco Magnacca Sante Ucchino Daniela Mastroiacovo Giovambattista Desideri Andrea Mezzetti Francesco Cipollone 2012Expert Opinion on Therapeutic Targets2012,,3:2
7Effect of tacrolimus (FKS06) on ischemia-induced brain damage and memory dysfunction in rats 显示文摘Benetoli A Paganelli RA 2004Pharmacol Biochem Behav2004,77,3:1
8Laparoscopic gastric banding prevents type 2 diabetes and arterial hypertension and induces their remission in morbid obesity:a 4-year case-controlled study显示文摘Pontiroli AE Folli F Paganelli M 2005Diabetes Care2005,28,11:1
9Optimization control strategy for hybrid fuel cell vehicle 显示文摘Gino Paganelli Yann Guezennec Giorgio Rizzoni 2002SAE PAPER2002,,1:1
10Piez- oelectric transducers for real-time evaluation of fruit firm- ness 显示文摘Enrico macrell Aldo Romani Rudi P Paganelli 2013Sensor and Actuators A: Physical2013,201,:1
11Radioimmunotherapy: is avidin-biotin pretargeting the preferred choice among pretargeting methods显示文摘 CHINOL M 2003Eur J Nucl Med Mol Imaging2003,,:1
12The Adam Smith Problem in Reverse : Self - Interest in the Wealth of Nations and the Theory of Moral Sentiments 显示文摘Paganelli Mafia Pia 2008History of Political Economy2008,40,2:1
13A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer显示文摘Veronesi U Paganelli G Viale G 2003N Eng J Med2003,349,6:1
14A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer 显示文摘Veronesi U Paganelli G Viale G 2003N Engl J Med2003,349,6:1
15Optimal power management of an experimental fuel cell/supercapaci-tor-powered hybrid vehicle显示文摘RODATZ P PAGANELLI G SCIARRETTA A 0,,01:1
16Preoperative PET/CT in early- stage breast cancer: is the TNM classification enough? 显示文摘Gilardi L Fumagalli L Paganelli G 2013Ann Oncol2013,24,3:1
17Vasodilator-stimulated phospho-protein phosphorylation analysis prior to percutaneous coronary intervention forexclusion of postprocedural major adverse cardiovascular events显示文摘Bonello L Paganelli F Arpin-Bornet M 2007J ThrombHaemost2007,5,8:1
18Hemodynamic effects of bilevel nasal positive airway pressure ventilation in patients with heart failure显示文摘Philip-Joet FF Paganelli FF Dutau HL 1999Respiration1999,66,:1
19Sentinel-lymphnode biopsy as a staging procedure in breast cancer: update of a randomised controlled study显示文摘Veronesi U Paganelli G Viale G 2006Lancet Oncol2006,7,12:1
20Influence of residual myocardial ischacmia on induced ventricular arrhythmias following a fwst acute myocardial infarction显示文摘Paganelli F Barnay P Joscht U 2001Eur Heart J2001,22,20:1
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