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| 1 | 污泥作为污水厂内碳源的水解特性及工艺选择显示文摘随着各地污水厂出水水质对氮、磷要求的日益提高,强化脱氮除磷成为必然要求,但是我国多数污水厂由于多种原因导致进水碳源不足,尤其是进水SCOD、VFAs的匮乏,直接影响了生物脱氮除磷的效率,甚至不得已采用人工投加外碳源脱氮或者化学除磷方式以满足严格的出水氮、磷要求,但这无疑大大提高了污水厂的产泥率及运行成本。充分挖掘污水厂的'内碳源',利用污泥水解产生VFAs,不仅能有效提高除磷脱氮效率,而且可以降低污水厂的污泥产量,是可持续的资源化技术。比较了初沉污泥和活性污泥的水解特性差异,介绍了污泥水解工艺的常用构型及参数选择,以及国内外一些成功的实施案例。 | 刘智晓 Sille Bendix Larsen Gert Petersen 马宝玲 | 2011 | 中国给水排水2011，27，22： | 20 |
| 2 | HCV-specific cytokine induction in monocytes of patients with different outcomes of hepatitis C显示文摘AIM:Cytokine release by macrophages critically determines the type of immune response to an antigen Therefore.we studied hepatitis C virus (HCV0-Specific induction of interleukins-1β,-10,-12(IL-1β,il-10,IL-12),and tumor necrosis factor-α(TNF-α) in monocytes.METHODS:Intracellular cytokine expression was studied by flow cytometry in 23 patients with chronic hepatitis C,14 anti-HCV seropositives without viremia and 11 controls after stimulation of peripheral blood mononuclear cells with recombinant core,NS3,NS4 NS5a and NS5b proteins .RESULTS:Patients with HCV viremia revealed greater spontaneous exprssion of IL-1β,TNF-α,and IL-10,Furthermore,greater than twofold higher IL-10 epression was induced by the HCV antigens in chronic hepatitis C than in the other two groups (P<0.05) In contrast,neither IL-12 noir TNF-α was induced preferentially.CONCLUSION:In chonic hepatitis C antigen-specific cytokine induction in monocytes is apparently shifted towards predominant IL-10 induction-not counterbalanced by antiviral type 1 cytokines,This may contribute to persistent viral replication. | Rainer P.Woitas Uwe Petersen Dirk Moshage Hans H.Brackmann Bertfried Matz Tilman Sauerbruch Ulrich Spengler | 2002 | World Journal of Gastroenterology2002，8，3： | 15 |
| 3 | 政府如何支持公私合营模式发展——20个欧洲国家PPP的政府支持情况评估比较显示文摘本文从制度的视角构建一个政府支持公私合营模式(Public Private Partnership,PPP)程度的指数——PPP政府支持指数(PPP Governmental Support Index,GSI)——以评估政府规定的制度体系对在交通基础设施和其他行业引入和推广PPP具有何种程度的促进或阻碍作用。首先,基于大量文献综述界定PPP政府支持指数的要素,包括关于PPP的政策和政治承诺、法律和监管框架,以及精心设计的PPP支持安排。其次,计算20个欧洲国家的PPP政府支持指数,将其分类并比较各国政府对基础设施领域PPP支持程度的异同。再次,探讨20个欧洲国家的制度指数得分与基础设施领域PPP行为的潜在联系。最后,讨论当前的PPP政府支持指数的潜力、实用性以及方法局限性,并详细阐述如何将该指数用于加强交通或其他领域PPP的比较研究中。 | Koen Verhoest Ole Helby Petersen Walter Scherrer Raden Murwantara Soecipto 张帆 | 2015 | 城市交通2015，13，4： | 13 |
| 4 | 低碳源条件下利用侧流活性污泥水解技术强化生物脱氮除磷显示文摘污水水质特性是决定生物脱氮除磷工艺处理效能的关键性影响因素,尤其是进水中可快速降解有机物(rbCOD)及挥发性脂肪酸(VFA)浓度与N、P浓度比值的高低,直接制约了N、P的去除效率,补加外部碳源往往成为污水处理厂迫不得已的选择,但是外部商业碳源会导致高昂的运行费用及其他运行问题。近十年来,充分挖掘优先利用污水处理厂内碳源技术在国外得到发展和应用。介绍了回流活性污泥(RAS)进行水解补充碳源的技术优势及工艺选择,就采用RAS侧流水解发酵在国内某厂实施技术示范项目进行了介绍,以期为国内在开发活性污泥可持续性利用技术方面提供借鉴。 | 刘智晓 Gert Petersen 张伟 Alexander Grossmann 詹卫东 | 2013 | 给水排水2013，39，1： | 11 |
| 5 | Control of cccDNA function in hepatitis B virus infection显示文摘 | Massimo Levrero Teresa Pollicino Jorg Petersen Laura Belloni Giovanni Raimondo Maura Dandri | 2009 | Journal of Hepatology2009，，3： | 8 |
| 6 | Can fecal microbiota transplantation cure irritable bowel syndrome?显示文摘AIM To verify the utility of treatment with fecal microbiota transplantation(FMT) in patients with irritable bowel syndrome(IBS).METHODS We searched EMBASE, Cochrane Library and Pub Med in March, 2017. The reviewed literature was based on two systematic searches in each of the databases. The Me SH terms used were IBS and fecal microbiota transplantation and the abbreviations IBS and FMT. Reference lists from the articles were reviewed to identify additional pertinent articles. RESULTS A total of six conference abstracts, one case report, one letter to the editor, and one clinical review were included. In the final analysis, treatment of 48 patients was evaluated. Treatment revealed an improvement in 58% of cases. The varying structure of the nine included studies must be taken into consideration.CONCLUSION Data on FMT and IBS are too limited to draw sufficientconclusions. Standardized double blinded randomized clinical trials need to be carried out to evaluate the effect of FMT on IBS. | Sofie Ingdam Halkjar Anders Watt Boolsen Stig Günther Alice Hojer Christensen Andreas Munk Petersen | 2017 | World Journal of Gastroenterology2017，23，22： | 8 |
| 7 | Offshore Windmill Farms:Threats to or Possibilities for the Marine Environment显示文摘欧洲已经计划在其沿岸大规模发展海上风力发电场。这就提出了有关对海洋环境的可能影响的重大问题。如果能够注意避开包含有稀有生境或物种的区域,那么施工期间的影响可能最大限度地减少到可忽略不计的程度。据我们现在所知,风力发动机运转期间,噪声、振动以及电磁场所造成的扰动,可认为对海洋环境的影响不大。礁体效应(即:增加一个硬底质)据信会对海洋环境造成不同尺度上的最大影响:小尺度影响,涉及材料、结构以及基底物质的不均匀性;中尺度影响:涉及护岸工程和防冲刷设施;大尺度影响:包括整个风力发电场的范围。本文联系从天然生境、人工礁以及海上其他人造构筑物所获得的研究结果探讨了这些不同尺度的影响。 | Jens Kjerulf Petersen Torleif Malm 林宝法(译) 胡恩和(校) | 2006 | AMBIO-人类环境杂志2006，35，2： | 8 |
| 8 | Biotechnological approaches in glucosinolate production显示文摘Glucosinolates(GLSs) are sulfur-rich, amino acid-derived defense compounds characteristic of the Brassicales order. In the past, GLSs were mostly known as anti-nutritional factors in fodder, biopesticides in agriculture, and flavors in condiments such as mustard. However, in recent times, GLSs have received increased attention as promoters of human health.This has spurred intensive research towards generating rich sources of health-promoting GLSs. We provide a comprehensive overview of the biotechnologica approaches applied to reach this goal. This includes optimization of GLS production and composition in native, GLS-producing plants, including hairy root and cell cultures thereof, as well as synthetic biology approaches in heterologous hosts, such as tobacco and the microbial organisms Escherichia coli and Saccharomyces cerevisiae. The progress using these different approaches is discussed. | Annette Petersen Cuiwei Wang Christoph Crocoll Barbara Ann Halkier | 2018 | Journal of Integrative Plant Biology2018，60，12： | 6 |
| 9 | 血压变异性预测自发性脑出血患者的院内不良预后显示文摘越来越多的证据表明,较高的收缩压变异性(systolicblood pressure variability ,SBPV)可能与脑出血患者的不良预后相关。该研究探讨了 SB PV 与院内脑出血预后之间的关系。研究者在2个医疗系统中收集了10年的自发性脑出血患者的连续数据。记录人口统计学、病史、实验室测试、计算机断层扫描数据、院内治疗情况以及神经和功能评估。在入院后24h内获取血压记录。 | 刘青 叶鹏 Divani AA Liu X Di Napoli M Lattanzi S Ziai W James ML Jafarli A Jafari M Saver JL Hemphill JC Vespa PM Mayer SA Petersen A | 2019 | 中华高血压杂志2019，27，8： | 6 |
| 10 | Cash holdings and R&D; smoothing显示文摘 | James R. Brown Bruce C. Petersen | 2010 | Journal of Corporate Finance2010，，3： | 6 |
| 11 | 脊髓刺激治疗痛性糖尿病性神经病变显示文摘痛性糖尿病性神经病变(PDN)的药物治疗通常不能完全缓解症状。由于脊髓刺激(SCS)在缓解疼痛方面显现出一定的疗效,因此本研究比较了10kHz SCS和常规治疗对PND的疗效。受试者为PDN症状超过12个月的患者,并且对加巴喷丁或普瑞巴林以及至少一种其他类型的镇痛药耐受。患者随机接受常规药物治疗(CMM)或10kHz SCS联CMM。主要结局终点为视觉模拟量表(VAS)评定疼痛减轻50%或以上,并且三个月内神经功能缺失无加重。 | Petersen E 王一祖(译) 潘文秀(译) 谢青(译) | 2021 | 中国康复2021，36，11： | 5 |
| 12 | FerryBox: Using Automated Water Measurement Systems to Monitor Water Quality: Perspectives for the Yangtze River and Three Gorges Dam显示文摘The building of the Three Gorges Dam (Hubei (湖北) Province, China) has transformed a region with an economy based on sustainable agriculture for millennia into an entirely different environment within an exceptionally short time. This disrupts the natural biogeochemical cycles of carbon, nutrients, and metals and possibly will affect the whole catchment including downstream ecosystems, such as wetlands, estuaries, deltas, and adjacent sea areas. Starting from changes that have already been documented, this article concentrates on the possible use of a 'FerryBox', which is an automated water quality measurement system on board a ship or on shore, to monitor the short and long term development of the quality of the river water in the backwater area and downstream of the dam. While there are already research programmes running to monitor the water quality of the river and the backwater area, these programs are limited to ship campaigns with sampling and laboratory analysis. The spatial and temporal resolution of such measurements is not sufficient for an overall assessment of the water quality and for prognoses in the context of anthropogenic and climate change. Therefore, a concept of applying regular automated observations by a FerryBox is presented. It is shown that such systems are very well suited to give feedback for the assessment of measures to improve the water quality. | Carsten Frank Friedhelm Schroeder Wilhelm Petersen | 2010 | Journal of Earth Science2010，21，6： | 5 |
| 13 | Role of simple biomarkers in predicting fibrosis progression in HCV infection显示文摘AIM: To examine the accuracy of the aspartate aminotransferase (AST)/Platelet Ratio Index (APRI) and FIB-4, in predicting longitudinal changes in liver histology in hepatitis C virus (HCV) patients.METHODS: Patients that underwent repeat liver biopsies at least 1 year apart from 1999 to 2007 were identified. Liver fibrosis was staged on needle core biopsies evaluated by a single expert liver pathologist. Only laboratory values within 3 mo of the liver biopsies were used.RESULTS: Thirty-six patients met the inclusion criteria with 50% stage 1 on initial biopsy, 25% stage 2, and 22% stage 3. Nineteen of 36 (53%) had progression of fibrosis on repeat biopsies, while 16 (44%) showed no change in stage, and one (3%) showed improvement. Patients that showed progression of fibrosis had significantly higher alanine aminotransferase and aspartate aminotransferase levels than the group that did not show progression. A significant correlation was seen between change in stage of fibrosis and change in APRI (r2 = 0.39, P = 0.00001) and a change in FIB-4 (r2 = 0.31, P = 0.00004). A change in APRI (ΔAPRI) of 0.18 had 80% positive predictive value (PPV) and 67% nega- tive predictive value (NPV) for progression of fibrosis. A change in FIB-4 (ΔFIB-4) of 0.39 had 75% PPV and 75% NPV for predicting progression of fibrosis. CONCLUSION: ΔAPRI and ΔFIB-4 parallel changes in fibrosis progression, and could be useful tools for clinicians in following patients with active chronic HCV infection. | Rajasekhara R Mummadi John R Petersen Ned Snyder | 2010 | World Journal of Gastroenterology2010，16，45： | 4 |
| 14 | Quality indicators for colonoscopy显示文摘 | Douglas K. Rex John L. Petrini Todd H. Baron Amitabh Chak Jonathan Cohen Stephen E. Deal Brenda Hoffman Brian C. Jacobson Klaus Mergener Bret T. Petersen Michael A. Safdi Douglas O. Faigel Irving M. Pike | 2006 | Gastrointestinal Endoscopy2006，，4： | 4 |
| 15 | Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade显示文摘 | Clifford R Jack David S Knopman William J Jagust Leslie M Shaw Paul S Aisen Michael W Weiner Ronald C Petersen John Q Trojanowski | 2010 | Lancet Neurology2010，，1： | 4 |
| 16 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 17 | 消化不良的流行病学和经济问题显示文摘非溃疡性消化不良是一种最常见的症状群,其发病机理尚未完全明瞭,治疗用药多而杂乱,疗效较难评价,然而,每年耗资甚大,严重影响社会劳动力.因此,本征的严重性,已开始引起我国消化系病临床工作者的重视。中美合资天津史克制药有限公司提供本刊一书(Practical Approaches to the Management of Dyspepsia),汇集了国际上知名学者对本症的诊治经验,对提高我们对本病的认识甚有助益.本刊特组织人员参加翻译,后经编辑部审校删节,以专辑形式刊出,供读者参考,并向史克公司表示谢忱. | Hermod Petersen 宋军 | 1990 | 临床消化病杂志1990，2，3： | 4 |
| 18 | Do financing constraints matter for R&D;?显示文摘 | James R. Brown Gustav Martinsson Bruce C. Petersen | 2012 | European Economic Review2012，，8： | 4 |
| 19 | Mild cognitive impairment as a diagnostic entity显示文摘 | Petersen RC | | Journal of Internal Medicine0，，： | 3 |
| 20 | A Procedure for Ranking Efficient Units in Data Envelopment Analysis显示文摘 | Per Andersen Niels Christian Petersen | 1993 | Management Science1993，，： | 3 |
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