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| 1 | Retrograde-viewing device improves adenoma detection rate in colonoscopies for surveillance and diagnostic workup显示文摘AIM:To determine which patients might benefit most from retrograde viewing during colonoscopy through subset analysis of randomized,controlled trial data.METHODS:The Third Eye Retroscope Randomized Clinical Evaluation(TERRACE) was a randomized,controlled,multicenter trial designed to evaluate the efficacy of a retrograde-viewing auxiliary imaging device that is used during colonoscopy to provide a second video image which allows viewing of areas on the proximal aspect of haustral folds and flexures that are difficult to see with the colonoscope's forward view.We performed a post-hoc analysis of the TERRACE data to determine whether certain subsets of the patient population would gain more benefit than others from use of the device.Subjects were patients scheduled for colonoscopy for screening,surveillance or diagnostic workup,and each underwent same-day tandem examinations with standard colonoscopy(SC) and Third Eye colonoscopy(TEC),randomized to SC followed by TEC or vice versa.RESULTS:Indication for colonoscopy was screening in 176/345 subjects(51.0%),surveillance after previous polypectomy in 87(25.2%) and diagnostic workup in 82(23.8%).In 4 subjects no indication was specified.Previously reported overall results had shown a net additional adenoma detection rate(ADR) with TEC of 23.2% compared to SC.Relative risk(RR) of missing adenomas with SC vs TEC as the initial procedure was 1.92(P = 0.029).Post-hoc subset analysis shows additional ADRs for TEC compared to SC were 4.4% for screening,35.7% for surveillance,55.4% for diagnostic and 40.7% for surveillance and diagnostic combined.The RR of missing adenomas with SC vs TEC was 1.11(P = 0.815) for screening,3.15(P = 0.014) for surveillance,8.64(P = 0.039) for diagnostic and 3.34(P = 0.003) for surveillance and diagnostic combined.Although a multivariate Poisson regression suggested gender as a possibly significant factor,subset analysis showed that the difference between genders was not statistically significant.Age,bowel prep quality and withdrawal time did not significantly affect the RR of missing adenomas with SC vs TEC.Mean sizes of adenomas detected with TEC and SC were similar at 0.59 cm and 0.56 cm,respectively(P = NS).CONCLUSION:TEC allows detection of significantly more adenomas compared to SC in patients undergoing surveillance or diagnostic workup,but not in screening patients(ClinicalTrials.gov Identifier:NCT01044732). | Peter D Siersema Amit Rastogi Anke M Leufkens Paul A Akerman Kassem Azzouzi Richard I Rothstein Frank P Vleggaar Alessandro Repici Giacomo Rando Patrick I Okolo Olivier Dewit Ana Ignjatovic Elizabeth Odstrcil James East Pierre H Deprez Brian P Saunders Anthony N Kalloo Bradley Creel Vikas Singh Anne Marie Lennon Daniel C DeMarco | 2012 | World Journal of Gastroenterology2012，18，26： | 6 |
| 2 | Psychological benefits of greenspace increase with biodiversity显示文摘 | Fuller Richard A Irvine Katherine N Devine-Wright Patrick Warren Philip H Gaston Kevin J | 2007 | Biology Letters2007，，4： | 2 |
| 3 | Dynamics of sediment discharge in relation to land use and hydro-climatol- ogy in a humid tropical watershed in costa rica 显示文摘 | JAGDISH K PATRICK N H DANIEL D R | 2001 | Journal of Hydrology2001，253，14： | 1 |
| 4 | 查看详情显示文摘 | Schuch R Garibian A Nygaard P Raymond S Araik G Hans H S Patrick J P Per N | | 0，，： | 1 |
| 5 | Support vector machines for histogram-based image classification显示文摘 | Olivier C Patrick H Vladimir N V | 1999 | IEEE Transactions on Neural Network1999，10，5： | 1 |
| 6 | Multiple independent emer- gences of type 2 vaccine-derived polioviruses during a large outbreak in northern Nigeria显示文摘 | Burns C C Shaw J Jorba J Bukbuk D Adu F Gumede N Pate M A Abanida E A Gasasira A Iber J Chen Q Vincent A Chenoweth P Henderson E Wannemuehler K Naeem A Umarni R N Nishimura Y Shimizu H Baba M Adeniji A Williams A J Kil- patrick D R Oberste M S Wassilak S G Tomori O Pallansch M A Kew O | 2013 | J Virol2013，87，9： | 1 |
| 7 | Differential requirement for RhoH in development of TCRalphabeta CD8alphaalpha IELs and other types of T cells 显示文摘 | Oda H Tamehiro N Patrick MS | 2013 | Immunol Lett2013，151，12： | 1 |
| 8 | Identification of the atomic scale structure of the La 0.65 Nd 0.15 Mg 0.20 Ni 3.5 alloy synthesized by spark plasma sintering显示文摘 | Virginie Serin Junxian Zhang César Magén Rapha?l Serra Martin J. H?tch Lucille Lemort Michel Latroche Manuel Ricardo Ibarra Bernard Knosp Patrick Bernard | 2013 | Intermetallics2013，，： | 1 |
| 9 | Plaque Composition and its Relationship With Acknowledged Shear Stress Patterns in Coronary Arteries显示文摘 | Gastón A. Rodriguez-Granillo Héctor M. García-García Jolanda Wentzel Marco Valgimigli Keiichi Tsuchida Wim van der Giessen Peter de Jaegere Evelyn Regar Pim J. de Feyter Patrick W. Serruys | 2006 | Journal of the American College of Cardiology2006，，4： | 1 |
| 10 | Knowledge-based design of reagentless fluorescent biosensors from recombinant antibodies显示文摘 | Martial R Laurent B Patrick N H | 2002 | J Mol Biol2002，318，： | 1 |
| 11 | Human Paragonimiasis After Eating Raw or Undercooked Crayfish - Missouri, July 2006-September 2010显示文摘 | Patrick S L Turabelidze G Marx H Grim A Lane M A Weil G J Bailey T C ?nen N F Demertzis L M Tuteur P G Hayes E V Davila S Z Folk S M Mitchem R E Kammerer E Fannon L P Jones J L Wilkins P P Lo Y C | 2010 | MMWR. Morbidity and Mortality Weekly Report2010，，： | 1 |
| 12 | Fast activation of a time-dependent outward current in protoplasts derived from coats of developing Phaseolus vulgaris seeds 显示文摘 | Zhang W H Walker N A Tyerman S D Patrick J W | 2000 | Planta2000，211，： | 1 |
| 13 | Soil pH effect on the distri- bution and plant availability of manganese, copper and zinc 显示文摘 | SINS Y N PATRICK H E | 1986 | Soil Science Society of America Journal1986，50，2： | 1 |
| 14 | Nicotine Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studiedin Achbp Crystal Structures显示文摘 | PATRICK H CELIE N SARAH E V | 2004 | Neuron2004，41，： | 1 |
| 15 | Fish detection and identification using neural networks-some laboratory results 显示文摘 | Ramani N Patrick P H | 1992 | IEEE Journal of Oceanic Engineering1992，17，4： | 1 |
| 16 | Effect of redox potential and pH on the uptake of cadmium and lead by rice plants显示文摘 | Reddy C N Patrick W H J | 1977 | Journal of Environmental Quality1977，6，： | 1 |
| 17 | Evaluation of a Fully Automated Serum Assay for Total N-Terminal Propeptide of Type I Collagen in Postmenopausal Os- teoporosis显示文摘 | Patrick G Philippe V H N | 2008 | Clin Chem2008，54，1： | 1 |
| 18 | The extracellular matrix protein MAGP-2 interacts with Jagged 1 and induces its sheclding from the cell surface 显示文摘 | Leslie C N Alison M Patrick W H | 2005 | J Biol Chem2005，21，20： | 1 |
| 19 | Is anterior leaflet repair always necessary in repair of bileaflet mitral valve prolapse?显示文摘 | A.Marc Gillinov Delos M Cosgrove Sudhir Wahi William J Stewart Bruce W Lytle Nicholas G Smedira Patrick M McCarthy Per N Wierup Joseph F Sabik Eugene H Blackstone | 1999 | The Annals of Thoracic Surgery1999，，3： | 1 |
| 20 | Effect of redox potential and pH on the uptake of cadmium and lead by rice plants显示文摘 | Reddy C N Patrick W H J | 1977 | Journal of Environmental Quality1977，6，3： | 1 |
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