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	题名	作者	年代	出处	被引量
1	Diagnosis of deep vein thrombosis,and prevention of deep vein thrombosis recurrence and the post-thrombotic syndrome in the primary care medicine setting anno 2014显示文摘The requirement for a safe diagnostic strategy of deep vein thrombosis(DVT) should be based on an overall objective post incidence of venous thromboembolism(VTE) of less than 1% during 3 mo fol low-up. Compression ultrasonography(CUS) of the leg veins has a negative predictive value(NPV) of 97%-98% indicating the need of repeated CUS testing within one week. A negative ELISA VIDAS safely excludes DVT and VTE with a NPV between 99% and 100% at a low clinical score of zero. The combination of low clinical score and a less sensitive D-dimer test(Simplify) is not sensitive enough to exclude DVT and VTE in routine daily practice. From prospective clinical research studies it may be concluded that complete recanalization within 3-6 mo and no reflux is associated with a low or no risk of PTS obviating the need of MECS 6 mo after DVT. Partial and complete recanalization after 6 to more than 12 mo is usually complicated by reflux due to valve destruction and symptomatic PTS. Reflux seems to be a main determinant for PTS and DVT recurrence, the latter as a main contributing factor in worsening PTS. This hypothesis is supported by the relation between the persistent residual vein thrombosis(RVT = partial recanalization) and the risk of VTE recurrence in prospective studies. Absence of RVT at 3 mo postDVT and no reflux is predicted to be associated with no recurrence of DVT(1.2%) during follow-up obviating the need of wearing medical elastic stockings and anticoagulation at 6 mo post-DVT. The presence or absence of RVT but with reflux at or after 6 mo postDVT is associated with both symptomatic PTS and an increased risk of VTE recurrence in about one third in the post-DVT period after regular discontinuation of anticoagulant treatment. To test this hypothesis we designed a prospective DVT and postthrombotic syndrome(PTS) Bridging the Gap Study by addressing at least four unanswered questions in the treatment ofDVT and PTS.Which DVT patient has a clear indication for long-term compression stocking therapy to prevent PTS after the initial anticoagulant treatment in the acute phase of DVT?Is 6 mo the appropriate point in time to determine candidates at risk to develop DVT recurrence and PTS?Which high risk symptomatic PTS patients need extended anticoagulant treatment?	Jan Jacques Michiels Janneke Maria Michiels Wim Moossdorff Mildred Lao Hanny Maasland Gualtiero Palareti	2015	World Journal of Critical Care Medicine2015，4，1：	14
2	Antithrombin III (ATILL) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study显示文摘	F. Baudo T. M. Caimi F. deCataldo A. Ravizza S. Arlati G. Casella D. Carugo G. Palareti C. Legnani L. Ridolfi R. Rossi A. D’Angelo L. Crippa D. Giudici G. Gallioli A. Wolfler G. Calori	1998	Intensive Care Medicine1998，，4：	2
3	A multi center evaluation of a new quantitative highly sensitive D- dimer assay for exclusion of venous thromboembolism 显示文摘	de Moerloose P Palareti G Aguilar CA	2008	Thromb Haemost2008，100，50：	1
4	D-dimer testing to determine the duration of anticoagulation therapy显示文摘	Palareti G Cosmi B Legnani C	2006	N Engl J Med2006，355，17：	1
5	Contribution of a new,rapid,quantitative and automated method for D-di-mer measurement to exclude deep vein thrombosis in symptomatic outpatients显示文摘	Legnani C Pancani C Palareti G		0，，2：	1
6	A multicenter evaluation of a new quantitative highly sensitive Ddimer assay for exclusion of venous thromboembolism显示文摘	de Moerloose P Palareti G Aguilar C	2008	Thromb Haemost2008，100，3：	1
7	Update on the predictive value of D- dimer in patients with idiopathic venous thromboembolism 显示文摘	COSMI B PALARETI G	2010	Thromb Rez2010，125，2：	1
8	Bleeding with anticoagulant treatments 显示文摘	Palareti G	2011	Hamo- staseologie2011，31，4：	1
9	Coagulative disorders in human acute pancreatitis role for the D - dimer 显示文摘	Salomone T Tosi P Palareti G	2003	Pancreas2003，26，2：	1
10	以D-二聚体检测确定抗凝治疗持续时间	Palareti G. Cosmi B. Legnani C. 马超	2007	世界核心医学期刊文摘(心脏病学分册)2007，0，4：	1
11	A mathematical model predicting anti-hepatitis B virus surface antigen(HBs) decay after vaccination against hepatitis B显示文摘	Honorati M C Palareti A Dolzani P	1999	Clin Exp Immunol1999，116，：	1
12	D-dimer testing to determine the duration of anticoagulation therapy显示文摘	Palareti G Cosmi B Legnani C	2006	N Engl J Med2006，355，17：	1
13	Different cutoff values of quantitative D-dimer methods to predict the risk of venous thromboembolism recurrence:a post-hoc analysis of the PROLONG study显示文摘	Leganai C Palareti G Cosmi B	2008	Haematologica2008，93，6：	1
14	Risk of venous thromboembolism re- currence: high negative predictive value of D-dimer performed after oral anticoagulation is stopped 显示文摘	Palareti G Legnani C Cosmi B	2002	Thromb Haemost2002，87，1：	1
15	Acritical appraisal of non-invasive diagnosisand exclusion of deep vein thrombosis and pulmonaryembolism in outpatients with suspected deep vein throm-bosis or pulmonary embolism: how many tests do we need显示文摘	Palareti G	2006	N Engl J Med2006，355，：	1
16	D-dimer testing to determine the duration of anticoagulant therapy显示文摘	Palareti G Cosmi B Legnani C	2007	Curr Opin Pulm Med2007，13，5：	1
17	D-dimmer testing to determine the duration of anticoagulant therapy显示文摘	PALARETI G COSMI B LEGNANI C	2007	Curr Opin Pulm Med2007，13，5：	1
18	Bleeding with anticoagulant treatments 显示文摘	Palareti G	2011	Hamostaseologie2011，31，4：	1
19	D-dimer testing to determine the duration of anticoagulation therapy 显示文摘	Palareti G Cosmi B Legnani C	2006	N Engl J Med2006，355，17：	1
20	Different cut off values of quantitative D-dimer methods to predict the risk of venous throm boembolism recurrence:a post-hoc analysis of the prolong study显示文摘	Legnani C Palareti G Cosmi B	2008	Haematologica2008，93，6：	1

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