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| 1 | Lack of association between UGT1A7,UGT1A9,ARP,SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients显示文摘AIM: To investigate simultaneously UGT1A7, UGT1A9, ARP, SPINK and CFTR genes to verify whether genetic polymorphisms predispose to the development of pancreatic cancer (PC). METHODS: Genomic DNA of 61 pancreatic cancer patients and 105 healthy controls (HC) were analyzed. UGT1A7 genotyping was determined by PCR-RFLP analysis. Specific PCR and sequencing were used to analyze genetic variants of UGT1A9, ARP, SPINK1 and CFTR genes. RESULTS: Four different alleles (*1: WT; *2: N129K and R131K; *3: N129K, R131K, and W208R; and *4: W208R) in UGT1A7 and three different alleles (*1: WT; *4: Y242X; and *5: D256N) in UGT1A9 were detected. All UGT1A polymorphisms were observed at similar frequency in PC patients and HC. Seven different alleles in ARP were found in PC patients and HC at similar frequency. The SPINK1 mutations N34S and P55S occurred in five PC patients with a prevalence (4.1%) not significantly different from that observed (2.0%) in HC. The only CFTR ΔF508 mutation was recognized in three PC patients with a prevalence (4.9%) similar to HC. CONCLUSION: UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms are not associated with PC in Italian patients. | Ada Piepoli Annamaria Gentile Maria Rosa Valvano Daniela Barana Cristina Oliani Rosa Cotugno Michele Quitadamo Angelo Andriulli Francesco Perri | 2006 | World Journal of Gastroenterology2006，12，39： | 3 |
| 2 | The Role of Lymphocytes in the Pathogenesis of Asthma and COPD显示文摘 | Oliani KL Turato G | 2007 | Curr Med Chem2007，14，21： | 1 |
| 3 | The intricate role of mast cell proteases and the annexin A1-FPR1 system in abdominal wall endometriosis 显示文摘 | PAULA R J R OLIANI A H VAZ-OLIANI D A | 2015 | J Mol Histol2015，46，1： | 1 |
| 4 | Teleultrasound: historical perspec- tive and clinical application显示文摘 | Ferreira AC O'Mahony E Oliani AH | 2015 | Int J Telemed Appl2015，，30： | 1 |
| 5 | Gap junctions between mast cells and fibroblasts in the developing avian eye显示文摘 | OLIANI S M GIROL A P SMITH R L | 1995 | Acta Anot1995，154，： | 1 |
| 6 | Fluctuation of annexin-A1 positive mast cells in chronic granulomatous inflammation显示文摘 | S. M. Oliani G. A. Panin Ciocca T. A. Pimentel A. S. Damazo L. Gibbs M. Perretti | 2008 | Inflammation Research2008，，10： | 1 |
| 7 | Study of Gel Formation by Ionizing Radiation in Polypmpylene 显示文摘 | Oliani W L Parra D F Femaino D M | 2013 | Radi- ation Physics and Chemistry2013，84，3： | 1 |
| 8 | The role of lymphocytes in the pathogenesis of asthma and COPD 显示文摘 | Baraldo S Lokar Oliani K Turato G | 2007 | Curr Med Chem2007，14，21： | 1 |
| 9 | The intricate role of mast cell proteases and the annexin A1-FPR1 system in abdominal wall endometriosis 显示文摘 | PAULA R J R OLIANI A H VAZ-OLIANI D C | 2015 | J Mol Histol2015，46，1： | 1 |
| 10 | HMSPP Nanocomposite and Brazilian Bentonite Properties AfterGamma Radiation Exposure 显示文摘 | Fermino D M Parra D F Oliani W L | 2013 | Radiation Physics and Chemistry2013，84，1： | 1 |
| 11 | Gap junctions between mast cells and fibroblasts in the develo-ping avian eye显示文摘 | Oliani S M Girol A P Smith R L | 1995 | Acta Anot1995，154，40： | 1 |
| 12 | UV Stability of HMS-PP (High Melt Strength Polypropylene) Obtained by Radiation Process显示文摘 | Oliani W L Parra D F Lugfio A B | 2010 | Radiation Phisics and Chemis- try2010，79，3： | 1 |
| 13 | Gemcitabine and continuous infusion of 5-fluorouracil in locally advanced and metastatic pancreatic cancer: a phase Ⅰ -Ⅱ study显示文摘 | Oliani C Padovani M Manno P | 2004 | Anticancer Res2004，24，3： | 1 |
| 14 | Effect of annexin-A1 peptide treatment during lung inflammation induced by lipopolysaccharide显示文摘 | Da C E Oliani S M Damazo A S | 2012 | Pulm Pharmacol Ther2012，25，4： | 1 |
| 15 | UV Stability of HMS- PP(High Melt Strength Polypropylene) Obtained by Radiation Process 显示文摘 | Oliani W L Parra D F Lug:o A B | 2010 | Radiat Phys Chem2010，79，3： | 1 |
| 16 | Predictive usefulness of urinary biomarkers for the identification of cyclosporine A- induced nephrotoxicity in a rat model显示文摘 | Carlos CP Sonehara NM Oliani SM | 2014 | PLoS One2014，9，10： | 1 |
| 17 | Myenteric denervation in gastric carcinogenesis: differential modulation ofnitric oxide and annexin - AI 显示文摘 | Polli - Lopes AC Estofolete CF Oliani SM | 2013 | Int J Clin Exp Pathol2013，6，1： | 1 |
| 18 | Gap junctions between mast cells and fibroblasts in the developing avian eye 显示文摘 | Oliani S M Girol A P Smith R L | 1995 | Acta Anot1995，154，40： | 1 |
| 19 | Expression of Annexin-A1 and Galectin-1 Anti-Inflammatory Proteins and mRNA in Chronic Gastritis and Gastric Cancer显示文摘 | Yvana Cristina Jorge Mayra Mioto Mataruco Leandro Pires Araújo Ana Flávia Teixeira Rossi Juliana Garcia de Oliveira Marina Curado Valsechi Alaor Caetano Kenji Miyazaki Célia Sebastiana de Jesus Fazzio Jorge Alberto Thomé Paula Rahal Sonia Maria Oliani Ana | 2013 | Mediators of Inflammation2013，，： | 1 |
| 20 | Physical ac-tivity attenuates neuropsychiatric disturbances and caregiver burden in patients with dementia显示文摘 | Christofoletti G Oliani MM Bucken-Gobbi LT | 2011 | Clinics(Sao Paulo)2011，66，4： | 1 |
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