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| 1 | Overexpression of c-met in the early stage of pancreatic carcinogenesis; altered expression is not sufficient for progression from chronic pancreatitis to pancreatic cancer显示文摘瞄准:在早胰腺的致癌作用期间调查遇见 c 的表示。方法:我们使用了 46 体积纸巾和 36 件微把样品,包括正常的胰,慢性胰炎,和胰腺的癌症,为量的即时反向的抄写聚合酶链反应。结果:大批,组织分析,胰腺的癌症纸巾显著地表示了高水平比遇见 c 做了慢性胰炎和正常的胰纸巾。遇见 c 的层次没在慢性胰炎和正常的胰纸巾之间不同。在基于 microdissection 的分析,遇见 c 比在正常管的上皮细胞在微把的胰腺的癌症房间和影响胰腺炎的上皮细胞在高水平被表示(两, P <
0.01 ) 。有趣地,影响胰腺炎的上皮细胞表示了层次遇见 c 类似于那些胰腺的癌症房间。结论:Overexpression 遇见 c 在胰腺的致癌作用的早阶段期间发生,并且遇见 c 的表示的单个改变不为到胰腺的癌症房间的长期的影响胰腺炎的上皮细胞的前进是足够的。 | Kenoki Ohuchida Kazuhiro Mizumoto Nami Ishikawa Yasuhiro Ogura Daisuke Yamada Takuya Egami Hayato Fujita Seiji Ohashi Eishi Nagai Masao Tanaka | 2006 | World Journal of Gastroenterology2006，12，24： | 4 |
| 2 | Intraductal Papillary Mucinous Neoplasms of the Pancreas With Distinct Pancreatic Ductal Adenocarcinomas Are Frequently of Gastric Subtype显示文摘 | Noboru Ideno Takao Ohtsuka Hiroshi Kono Kenji Fujiwara Yasunori Oda Shinichi Aishima Tetsuhide Ito Kousei Ishigami Shoji Tokunaga Kenoki Ohuchida Shunichi Takahata Masafumi Nakamura Kazuhiro Mizumoto Masao Tanaka | 2013 | Annals of Surgery2013，，1： | 2 |
| 3 | Predicting the chemosensitivity of pancreatic cancer cells by quantifyingthe expression levels of genes associated with the metabolism of gemcitabine and5-fluorouracil显示文摘 | Nobuaki Kurata Hayato Fujita Kenoki Ohuchida Kazuhiro Mizumoto Prawej Mahawithitwong Hiroshi Sakai Manabu Onimaru Tatsuya Manabe Takao Ohtsuka Masao Tanaka | 2011 | International Journal of Oncology2011，，2： | 2 |
| 4 | The role of S100A6 in pancreatic cancer development and its clinical implication as a diagnostic marker and therapeutic target显示文摘 | Ohuchida K Mizumoto K Ishikawa N | 2005 | Clin Cancer Res2005，11，21： | 1 |
| 5 | Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions显示文摘 | Ohuchida K Mizumoto K Murakami M | 2004 | Can Res2004，64，： | 1 |
| 6 | MicroRNA-203 ex-pression as a new prognostic marker of pancreatic adenocarcino-ma显示文摘 | Kenaga N Ohuchida K Mizumoto K | | 0，，12： | 1 |
| 7 | SLOOP is an early developmental marker of pancreatic carcinogenesis 显示文摘 | Ohuchida K Mizumoto K Egami T | 2006 | Clin Cancer Res2006，12，18： | 1 |
| 8 | Enhanced cell migration and invasion of CD133+pancreatic cancer cells cocultured with pancreatic stromal cells显示文摘 | Moriyama T Ohuchida K Mizumoto K | 2010 | Cancer2010，116，： | 1 |
| 9 | Combination with low-dose gemcitabine and hTERT-promoter-dependent condi- tionally replicative adenovirus enhances cytotoxicity through their crosstalk mechanisms in pancreatic cancer显示文摘 | Onimaru M Ohuchida K Nagai E | 2010 | Cancer Lett2010，294，2： | 1 |
| 10 | Twist,a novel oncogene,is upregulated in pancreatic cancer:clinical implication of Twist expression in pancreatic juice显示文摘 | Ohuchida K Mizumoto K Ohhashi S | 2007 | Int J Cancer2007，120，8： | 1 |
| 11 | Long-term results of treatment for pancreaticobiliary maljunction without bile duct dilatation显示文摘 | Ohuchida J Chijiiwa K Hiyoshi M | 2006 | Arch Surg2006，141，11： | 1 |
| 12 | MicroRNA expres-sion as a predictive marker for gemcitabine response after surgical resection of pancreatic cancer显示文摘 | Ohuchida K Mizumoto K Kayashima T | | 0，，22： | 1 |
| 13 | MicroRNA miR- 17-5p is overexpressed in pancreatic cancer, associated with a poor prognosis, and involved in cancer cell prolif- eration and invasion 显示文摘 | Yu J Ohuchida K Mizumoto K | 2010 | Cancer Biol Ther2010，10，8： | 1 |
| 14 | MicroRNA-10a is overexpressed in human pancoatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene显示文摘 | Ohuchida K Mizumoto K Lin C | 2012 | Ann Surg Ortcol2012，19，7： | 1 |
| 15 | Increased expression of ADAM9 and ADAM15 Mrna in pancreatic caneer显示文摘 | Yamad D Ohuchida K Mizumoto K | 2007 | Anti-canc- er Res2007，27，2： | 1 |
| 16 | MicroRNA-21 modu- lates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance显示文摘 | Moriyama T Ohuchida K Mizumoto K | 2009 | Mol Cancer Ther2009，8，5： | 1 |
| 17 | MicroRNA-10a is overexpressed in hurman pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene显示文摘 | Ohuchida K Mizumoto K Lin C | 2012 | Ann Surg Oncol2012，19，： | 1 |
| 18 | MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation,invasion, and chemoresistance显示文摘 | MORIYAMA T OHUCHIDA K MIZUMOTO K | 2009 | Mol Cancer Ther2009，8，5： | 1 |
| 19 | MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation显示文摘 | Yu J Ohuchida K Mizumoto K | 2010 | Mol Cancer2010，9，： | 1 |
| 20 | Long-term results of treatment of pancreaticobiliary maljunction without bile duct dilatation显示文摘 | Ohuchida J Chijiiwa K Hiyoshi M Kobayashi K Konomi H Tanaka M | 2006 | Arch Surg2006，141，： | 1 |
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