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| 1 | Ischemic Preconditioning Protects the Pig Liver by Preserving the Mitochondrial Structure and Downregulating Caspase-3 Activity显示文摘 | Rafael Omar Giovanardi Ernani Luis Rhoden Carlos Thadeu Cerski Miriam Salvador Antonio Nocchi Kalil | 2009 | Investigative Surgery2009,,2: | 1 |
| 2 | Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3and ascorbate to trigger cell death显示文摘 | Tomasetti M Nocchi L Neuzil J | 2012 | Plos One2012,7,: | 1 |
| 3 | Clinical significance of circulating miR-126 quantification in malignant mesothelioma patients显示文摘 | Tomasetti M Stafolani S Nocchi L | 2012 | Clin Biochem2012,45,78: | 1 |
| 4 | A conceptual and numerical model for groundwater management:a case study on a coastal aquifer in southern Tuscany,Italy显示文摘 | BARAZZUOLI P NOCCHI M RIGATI R | 2008 | Hydrogeology Journal2008,16,8: | 1 |
| 5 | Safe wrapping of the bor- derline dilated ascending aorta during aortic valve replacement显示文摘 | Tappainer E Fiorani V Nocchi A | 2007 | J Cardiothorac Surg2007,2,: | 1 |
| 6 | Clinical significance of circulating miR-126 quantification in malignant mesothelioma pa- tients 显示文摘 | Tomasetti M Staffolani S Nocchi L | 2012 | Clin Biochem2012,45,78: | 1 |
| 7 | MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial function显示文摘 | Tomasetti M Nocchi L Staffolani S | 2014 | Antioxid Redox Signal2014,21,15: | 1 |
| 8 | Isolation and expansion of equine umbilical cord-derived matrix cells (EUCMCs) 显示文摘 | Passeri S Nocchi F Lamanna R | 2009 | Cell Biol Int2009,33,1: | 1 |
| 9 | Antioxidant properties and total phenolic contents of some tropical seaweeds of the Brazilian coast显示文摘 | Cintia D. Leal Martins Fernanda Ramlov Nathália Peixoto Nocchi Carneiro Lisia M. Gestinari Bruno F. dos Santos Lilian M. Bento Cintia Lhullier Lidiane Gouvea Eduardo Bastos Paulo A. Horta Angelica R. Soares | 2013 | Journal of Applied Phycology2013,,: | 1 |
| 10 | Different media and supplements modulate the clonogenic and expansion properties of rabbit bone marrow mesenchymal stem cells显示文摘 | Lapi S Nocchi F Lamanna R | 2008 | BMC Res Notes2008,28,1: | 1 |
| 11 | Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death显示文摘 | Tomasetti M Nocchi L Neuzil J | 2012 | PLoS One2012,7,: | 1 |
| 12 | Primary liver transplantation vs transplant after Kasai portoenterostomy in children with biliary atresia: A retrospective Brazilian single-center cohort显示文摘BACKGROUND Biliary atresia(BA)is the most common indication for pediatric liver transplantation,although portoenterostomy is usually performed first.However,due to the high failure rate of portoenterostomy,liver transplantation has been advocated as the primary procedure for patients with BA.It is still unclear if a previous portoenterostomy has a negative impact on liver transplantation outcomes.AIM To investigate the effect of prior portoenterostomy in infants un-dergoing liver transplantation for BA.METHODS This was a retrospective cohort study of 42 pediatric patients with BA who underwent primary liver transplantation from 2013 to 2023 at a single tertiary center in Brazil.Patients with BA were divided into two groups:Those undergoing primary liver transplantation without portoenterostomy and those undergoing liver transplantation with prior portoenterostomy.Continuous variables were compared using the Student’s t-test or the Kruskal-Wallis test,and categorical variables were compared using theχ2 or Fisher’s exact test,as appropriate.Multivariable Cox regression analysis was performed to determine risk factors for portal vein thrombosis.Patient and graft survival analyses were conducted with the Kaplan–Meier product-limit estimator,and patient subgroups were compared using the two-sided log-rank test.RESULTS Forty-two patients were included in the study(25[60%]girls),23 undergoing liver transplantation without prior portoenterostomy,and 19 undergoing liver transplantation with prior portoenterostomy.Patients with prior portoenterostomy were older(12 vs 8 months;P=0.02)at the time of liver transplantation and had lower Pediatric End-Stage Liver Disease scores(13.2 vs 21.4;P=0.01).The majority of the patients(35/42,83%)underwent livingdonor liver transplantation.The group of patients without prior portoenterostomy appeared to have a higher incidence of portal vein thrombosis(39 vs 11%),but this result did not reach statistical significance.Prior portoenterostomy was not a protective factor against portal vein thrombosis in the multivariable analysis after adjusting for age at liver transplantation,graft-to-recipient weight ratio,and use of vascular grafts.Finally,the groups did not significantly differ in terms of post-transplant survival.CONCLUSION In our study,prior portoenterostomy did not significantly affect the outcomes of liver transplantation. | Melina Utz Melere Valberto Sanha Marco Farina Carolina Soares da Silva Luiza Nader Cristine Trein Angelica Maria Lucchese Cristina Ferreira Antonio Nocchi Kalil Flavia Heinz Feier | 2024 | World Journal of Transplantation2024,14,1: | 0 |
| 13 | Liver volumetric and anatomic assessment in living donor liver transplantation: The role of modern imaging and artificial intelligence显示文摘The shortage of deceased donor organs has prompted the development of alternative liver grafts for transplantation.Living-donor liver transplantation(LDLT)has emerged as a viable option,expanding the donor pool and enabling timely transplantation with favorable graft function and improved long-term outcomes.An accurate evaluation of the donor liver’s volumetry(LV)and anatomical study is crucial to ensure adequate future liver remnant,graft volume and precise liver resection.Thus,ensuring donor safety and an appropriate graftto-recipient weight ratio.Manual LV(MLV)using computed tomography has traditionally been considered the gold standard for assessing liver volume.However,the method has been limited by cost,subjectivity,and variability.Automated LV techniques employing advanced segmentation algorithms offer improved reproducibility,reduced variability,and enhanced efficiency compared to manual measurements.However,the accuracy of automated LV requires further investigation.The study provides a comprehensive review of traditional and emerging LV methods,including semi-automated image processing,automated LV techniques,and machine learning-based approaches.Additionally,the study discusses the respective strengths and weaknesses of each of the aforementioned techniques.The use of artificial intelligence(AI)technologies,including machine learning and deep learning,is expected to become a routine part of surgical planning in the near future.The implementation of AI is expected to enable faster and more accurate image study interpretations,improve workflow efficiency,and enhance the safety,speed,and cost-effectiveness of the procedures.Accurate preoperative assessment of the liver plays a crucial role in ensuring safe donor selection and improved outcomes in LDLT.MLV has inherent limitations that have led to the adoption of semi-automated and automated software solutions.Moreover,AI has tremendous potential for LV and segmentation;however,its widespread use is hindered by cost and availability.Therefore,the integration of multiple specialties is necessary to embrace technology and explore its possibilities,ranging from patient counseling to intraoperative decision-making through automation and AI. | Mayara Machry Luis Fernando Ferreira Angelica Maria Lucchese Antonio Nocchi Kalil Flavia Heinz Feier | 2023 | World Journal of Transplantation2023,13,6: | 0 |