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| 1 | Diagnostic value of glypican-3 in serum and liver for primary hepatocellular carcinoma显示文摘AIM:To evaluate the diagnostic value of glypican-3(GPC3) in serum and liver for primary hepatocellular carcinoma(HCC).METHODS:Serum levels of GPC3 and α-fetoprotein(AFP) were measured in 75 patients with primary HCC and 32 patients with liver cirrhosis.Expression of GPC3 and AFP in 58 HCC and 12 cirrhotic specimens was detected with immunohistochemical staining.RESULTS:When the cut-off value of serum GPC3 was set at 300 ng/L,its sensitivity and specificity for HCC were 47.0% and 93.5%,respectively.Among the 14 patients with HCC at stage according to the Barcelona Clinic Liver Cancer staging system,the serum GPC3 level was higher than 300 ng/L in 50%(7/14) patients,the serum AFP level was not ≥ 400 μg/L in any patient.Combined serum AFP and GPC3 significantly increased the sensitivity to the diagnosis of HCC.The GPC3 expression was detected in cytoplasm of HCC cells but not in hepatocytes and bile ducts of benign tumors.Among the 58 HCC patients,the GPC3 was expressed in 100%(28/28) patients with their serum AFP level ≥ 400 μg/L,and in 90%(27/30) patients with their AFP level < 400 μg/L,respectively.The GPC3 was weakly or negatively expressed in all paracarcinomatous and cirrhotic tissue samples.AFP positive HCC cells were only found in 1 out of the 58 HCC patients.CONCLUSION:GPC3 protein is a sensitive and specific serum marker for diagnosis of early HCC.Its expression in liver tissues can be used to discriminate tumor cells from benign hepatic cells. | Hui Liu Li-Jie Zhang Peng Li Yun Zhai Yu-Fen Tan Ning Li Hui-Guo Ding Chun-Feng Qu | 2010 | World Journal of Gastroenterology2010，16，35： | 57 |
| 2 | Shake table tests of suspended ceilings to simulate the observed damage in the M_s 7.0 Lushan earthquake, China显示文摘Severe damage to suspended ceilings of metal grids and lay-in panels was observed in public buildings during the 2013 Ms7.0 Lushan earthquake in China. Over the past several years, suspended ceilings have been widely used practice in public buildings throughout China, including government offices, schools and hospitals. To investigate the damage mechanism of suspended ceilings, a series of three-dimensional shake table tests was conducted to reproduce the observed damage. A full-scale reinforced concrete frame was constructed as the testing frame for the ceiling, which was single-story and infilled with brick masonry walls to represent the local construction of low-rise buildings. In general, the ceiling in the tests exhibited similar damage phenomena as the field observations, such as higher vulnerability of perimeter elements and extensive damage to the cross runners. However, it exhibited lower fragility in terms of peak ground/roof accelerations at the initiation of damage. Further investigations are needed to clarify the reasons for this behavior. | Wang Duozhi Dai Junwu Qu Zhe Ning Xiaoqing | 2016 | Earthquake Engineering and Engineering Vibration2016，15，2： | 13 |
| 3 | Epidemiological Data of Work-Related Musculoskeletal Disorders—China,2018–2020显示文摘Summary What is already known about this topic?In recent decades,work-related musculoskeletal disorders(WMSDs)have become increasingly prominent and have become an important issue that is of universal concern and an urgent need to be solved in all countries of the world.What is added by this report?The top three industries or occupational groups with the highest standardized prevalence rate of WMSDs were flight attendants,medical staff,and vegetable greenhouses in that order.Women workers were 1.5 times more likely to suffer from WMSDs than men workers. | Ning Jia Huadong Zhang Ruijie Ling Yimin Liu Gang Li Zaoliang Ren Yan Yin Hua Shao Hengdong Zhang Bing Qiu Meibian Zhang Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2021 | China CDC weekly2021，3，18： | 13 |
| 4 | Treatment of coking wastewater by a novel electric assisted micro-electrolysis filter显示文摘A newly designed electric assisted micro-electrolysis filter(E-ME) was developed to investigate its degradation efficiency for coking wastewater and correlated characteristics. The performance of the E-ME system was compared with separate electrolysis(SE) and micro-electrolysis(ME) systems. The results showed a prominent synergistic effect on COD removal in E-ME systems. Gas chromatography/mass spectrometry(GC–MS) analysis confirmed that the applied electric field enhanced the degradation of phenolic compounds.Meanwhile, more biodegradable oxygen-bearing compounds were detected. SEM images of granular activated carbon(GAC) showed that inactivation and blocking were inhibited during the E-ME process. The effects of applied voltage and initial p H in E-ME systems were also studied. The best voltage value was 1 V, but synergistic effects existed even with lower applied voltage. E-ME systems exhibited some p H buffering capacity and attained the best efficiency in neutral media, which means that there is no need to adjust p H prior to or during the treatment process. Therefore, E-ME systems were confirmed as a promising technology for treatment of coking wastewater and other refractory wastewater. | Ruosong Xie Miaomiao Wu Guangfei Qu Ping Ning Yingying Cai Pei Lv | 2018 | Journal of Environmental Sciences2018，30，4： | 12 |
| 5 | Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。 | Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba | 2016 | Protein & Cell2016，7，2： | 11 |
| 6 | Carbon sinks/sources in the Yellow and East China Seas Air-sea interface exchange, dissolution in seawater, and burial in sediments显示文摘The sinks/sources of carbon in the Yellow Sea(YS) and East China Sea(ECS), which are important continental shelf seas in China, could exert a great influence on coastal ecosystem dynamics and the regional climate change process. The CO_2 exchange process across the seawater-air interface, dissolved and particulate carbon in seawater, and carbon burial in sediments were studied to understand the sinks/sources of carbon in the continental shelf seas of China. The YS and the ECS generally have different patterns of seasonal air-sea CO_2 exchange. In the YS, regions west of 124°E can absorb CO_2 from the atmosphere during spring and winter, and release CO_2 to the atmosphere during summer and autumn. The entire YS is considered as a CO_2 source throughout the year with respect to the atmosphere, but there are still uncertainties regarding the exact air-sea CO_2 exchange flux. Surface temperature and phytoplankton production were the key controlling factors of the air-sea CO_2 exchange flux in the offshore region and nearshore region of the YS, respectively. The ECS can absorb CO_2 during spring, summer, and winter and release CO_2 to the atmosphere during autumn. The annual average exchange rate in the ECS was-4.2±3.2 mmol m^(-2) d^(-1) and it served as an obvious sink for atmospheric CO_2 with an air-sea exchange flux of 13.7×10~6 t. The controlling factors of the air-sea CO_2 exchange in the ECS varied significantly seasonally. Storage of dissolved inorganic carbon(DIC) and dissolved organic carbon(DOC) in the YS and the ECS were 425×10~6 t and 1364×10~6 t, and 28.2×10~6 t and 54.1×10~6 t,respectively. Long-term observation showed that the DOC content in the YS had a decreasing trend, indicating that the 'practical carbon sink' in the YS was decreasing. The total amount of particulate organic carbon(POC) stored in the YS and ECS was10.6×10~6 t, which was comparable to the air-sea CO_2 flux in these two continental shelf seas. The amounts of carbon sequestered by phytoplankton in the YS and the ECS were 60.42×10~6 t and 153.41×10~6 t, respectively. Artificial breeding of macroalgae could effectively enhance blue carbon sequestration, which could fix 0.36×10~6–0.45×10~6 t of carbon annually. Organic carbon(OC) buried in the sediments of the YS was estimated to be 4.75×10~6 t, and OC of marine origin was 3.03×10~6 t, accounting for5.0% of the TOC fixed by phytoplankton primary production. In the ECS, the corresponding depositional flux of OC in the sediment was estimated to be 7.4×10~6 t yr^(-1), and the marine-origin OC was 5.5×10~6 t, accounting for 5.4% of the phytoplankton primary production. Due to the relatively high average depositional flux of OC in the sediment, the YS and ECS have considerable potential to store a vast amount of 'blue carbon.' | Jinming SONG Baoxiao QU Xuegang LI Huamao YUAN Ning LI Liqin DUAN | 2018 | Science China Earth Sciences2018，61，11： | 11 |
| 7 | Investigation on Work-Related Musculoskeletal Disorders--China, 2018−2019显示文摘What is already known about this topic?Work-related musculoskeletal disorders(WMSDs)have a high prevalence and seriously harmful,which has attracted extensive attention in various countries in the world.Currently,the occurrence and rules of WMSDs in key industries are not known in China.What is added by this report?The prevalence of WMSDs is relatively high among professional populations in key industries in China,with the most commonly affected body parts concentrated in neck,shoulders,and low back and increasing with age and working years.What are the implications for public health practice?This study determined the prevalence and distribution characteristics of WMSDs in key industries in China and provided scientific evidence to recommend for inclusion of WMSDs in the new revision of the list of occupational diseases in China. | Ning Jia Huadong Zhang Ruijie Ling Yimin Liu Gang Li Zaoliang Ren Yan Yin Hua Shao Hengdong Zhang Bing Qiu Meibian Zhang Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2020 | China CDC weekly2020，2，18： | 11 |
| 8 | Internet of Things to network smart devices for ecosystem monitoring显示文摘Smart, real-time, low-cost, and distributed ecosystem monitoring is essential for understanding and managing rapidly changing ecosystems. However, new techniques in the big data era have rarely been introduced into operational ecosystem monitoring, particularly for fragile ecosystems in remote areas.We introduce the Internet of Things(IoT) techniques to establish a prototype ecosystem monitoring system by developing innovative smart devices and using IoT technologies for ecosystem monitoring in isolated environments. The developed smart devices include four categories: large-scale and nonintrusive instruments to measure evapotranspiration and soil moisture, in situ observing systems for CO2 and d13 C associated with soil respiration, portable and distributed devices for monitoring vegetation variables, and Bi-CMOS cameras and pressure trigger sensors for terrestrial vertebrate monitoring. These new devices outperform conventional devices and are connected to each other via wireless communication networks. The breakthroughs in the ecosystem monitoring IoT include new data loggers and longdistance wireless sensor network technology that supports the rapid transmission of data from devices to wireless networks. The applicability of this ecosystem monitoring IoT is verified in three fragile ecosystems, including a karst rocky desertification area, the National Park for Amur Tigers, and the oasis-desert ecotone in China. By integrating these devices and technologies with an ecosystem monitoring information system, a seamless data acquisition, transmission, processing, and application IoT is created. The establishment of this ecosystem monitoring IoT will serve as a new paradigm for ecosystem monitoring and therefore provide a platform for ecosystem management and decision making in the era of big data. | Xin Li Ning Zhao Rui Jin Shaomin Liu Xiaomin Sun Xuefa Wen Dongxiu Wu Yan Zhou Jianwen Guo Shiping Chen Ziwei Xu Mingguo Ma Tianming Wang Yonghua Qu Xinwei Wang Fangming Wu Yuke Zhou | 2019 | Science Bulletin2019，64，17： | 10 |
| 9 | Physicians’Perception of Palliative Care Consultation Service in a Major General Hospital in China显示文摘Objectives The in-hosptial palliative care consultation(PCC)is emerging as a routine service in some medical center in China.The current study evaluated how physicians in primary care team and consultation team perceive the PCC service for the purpose of investigating the effectiveness of this consultation model in a general hospital.Methods In-hosptial palliative care consultations have been carried out at Peking Union Medical College Hosptial by a dedicated consultation team,and37consultations were completed in2016.A questionnaire was designed for physicians in terms of its benefits to patients,their family as well as the primary care team.Physicians who applied for consultation in2016formally(requested from the department other than the Geriatrics)and informally(by rotating residents and unemployed visiting doctors in geriatric department)were invited to participate in the survey by scanning a two dimentional code on social networking platform.Results There were103physicians participated in the survey,including primary care physicians from the department of Internal Medicine(n=8),Gynaecology(n=16)and Surgery(n=13),rotating residents(n=30),visiting doctors(n=16)in Geriatric department,and PCC team members(n=20).94.0%of the non-PCC physicians agreed that PCC relieved the suffering of patients;89.2%thought PCC improved the quality of patients'life;there were91.6%,95.2%,90.4%physicians who felt it relieved the anxiety of patients,of family members and of care providers,respectively.There were96.4%physicians who felt it could ease the tension in physician-patient relationship;97.6%felt it lower the risk for medical negligence,and96.4%of doctors who applied for PPC felt satisfied with PCC service in terms of process and achieving objectives of consultation.More primary-team physician agree'PCC service helps the physicians better understand palliative care'than PCC members(97.6%vs.80%,P<0.05),while both were interested in learning more on palliative medicine(100%vs.96.4%,P>0.05). | Xuan Qu Nan Jiang Nan Ge Xiaohong Ning | 2018 | Chinese Medical Sciences Journal2018，33，4： | 9 |
| 10 | Full time-domain nonlinear coupled dynamic analysis of a truss spar and its mooring/riser system in irregular wave显示文摘A new full time-domain nonlinear coupled method has been established and then applied to predict the responses of a Truss Spar in irregular wave.For the coupled analysis,a second-order time-domain approach is developed to calculate the wave forces,and a finite element model based on rod theory is established in three dimensions in a global coordinate system.In numerical implementation,the higher-order boundary element method(HOBEM)is employed to solve the velocity potential,and the 4th-order Adams-Bashforth-Moultn scheme is used to update the second-order wave surface.In deriving convergent solutions,the hull displacements and mooring tensions are kept consistent at the fairlead and the motion equations of platform and mooring-lines/risers are solved simultaneously using Newmark-integration scheme including Newton-Raphson iteration.Both the coupled quasi-static analysis and the coupled dynamic analysis are performed.The numerical simulation results are also compared with the model test results,and they coincide very well as a whole.The slow-drift responses can be clearly observed in the time histories of displacements and mooring tensions.Some important characteristics of the coupled responses are concluded. | YANG MinDong TENG Bin XIAO LongFei NING DeZhi SHI ZhongMin QU Yan | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，1： | 8 |
| 11 | Development of mouse preimplantation embryos in space显示文摘The development o f life beyond planet Earth is a long-standing quest of the human race,but whether normal mammalian embryonic development can occur in space is still unclear.Here,we show unequivocally that preimplantation mouse embryos can develop in space;but the rate of blastocyst formation and blastocyst quality are compromised.Additionally,the cells in the embryo contain severe DNA damage,while the genome of the blastocysts developed in space is globally hypomethylated with a unique set of differentially methylated regions.The developmental defects,DNA damage and epigenetic abnormalities can be largely mimicked by the treatment with ground-based low-dose radiation.However,the exposure to simulated microgravity alone does not cause major disruptions of embryonic development,indicating that radiation is the main cause for the developmental defects.This work advances the understanding of embryonic development in space and reveals long-term extreme low-dose radiation as a hazardous factor for mammalian reproduction. | Xiaohua Lei Yujing Cao Baohua Ma Yunfang Zhang Lina Ning Jingjing Qian Liwen Zhang Yongcun Qu Tao Zhang Dehong Li Qi Chen Junchao Shi Xudong Zhang Chiyuan Ma Ying Zhang Enkui Duan | 2020 | National Science Review2020，7，9： | 8 |
| 12 | Work-family conflict and job burn-out among Chinese doctors:the mediating role of coping styles显示文摘Background Burn-out among doctors threatens their own health, and that of their patients. To identify risk factors of the doctor burn-out is vital to improving their health and increasing the quality of healthcare services.This study aims to explore the relationship between workfamily conflict(WFC) and burn-out among Chinese doctors and the mediating role of coping styles in this relationship.Methods A cross-sectional survey was conducted in China, with a questionnaire packet which consisted of the Chinese Maslach Burnout Inventory(CMBI), WFC Scale and the Simplified Coping Style Questionnaire(SCSQ). A total of 2530 doctors participated in the survey. Correlation analysis was performed to explore the relationship between CMBI, WFC and SCSQ scores. A linear regression model was set to determine the mediating role of coping styles on the relationship between WFC and burn-out.Results Doctors who had higher scores on work interfering with family conflict, reported more emotional exhaustion(r=0.514, P<0.001) and had a sense of accomplishment(r=-0.149, P<0.001). Simultaneously,family interfering with work(FIW) was positively associated with all dimensions of burn-out(r=0.213,0.504,0.088,respectively, P<0.001). Coping styles had partial, complete and even mediating effects on the relationship between WFC and burn-out among Chinese doctors.Conclusions WFC was correlated with burn-out, and coping style was a mediator in this relationship among Chinese doctors. Coping style was a positive resource against burn?out. | Ling Chen Junjun Liu Hailong Yang Hui Ma Hui Wang Yun Huang Hao Cheng Dianzhen Tang Miao Liu Houyuan Luo Haitao Qu Diwen Shen Ning Zhang | 2018 | General Psychiatry2018，31，4： | 7 |
| 13 | Diversity and redundancy of the ripening regulatory networks revealed by the fruitENCODE and the new CRISPR/Cas9 CNR and NOR mutants显示文摘Tomato is considered as the genetic model for climacteric fruits,in which three major players control the fruit ripening process:ethylene,ripening transcription factors,and DNA methylation.The fruitENCODE project has now shown that there are multiple transcriptional circuits regulating fruit ripening in different species,and H3K27me3,instead of DNA methylation,plays a conserved role in restricting these ripening pathways.In addition,the function of the core tomato ripening transcription factors is now being questioned.We have employed CRISPR/Cas9 genome editing to mutate the SBP-CNR and NAC-NOR transcription factors,both of which are considered as master regulators in the current tomato ripening model.These plants only displayed delayed or partial non-ripening phenotypes,distinct from the original mutant plants,which categorically failed to ripen,suggesting that they might be gain-of-function mutants.Besides increased DNA methylation genome-wide,the original mutants also have hyper-H3K27me3 in ripening gene loci such as ACS2,RIN,and TDR4.It is most likely that multiple genetic and epigenetic factors have contributed to their strong non-ripening phenotypes.Hence,we propose that the field should move beyond these linear and twodimensional models and embrace the fact that important biological processes such as ripening are often regulated by highly redundant network with inputs from multiple levels. | Ying Gao Ning Zhu Xiaofang Zhu Meng Wu Cai-Zhong Jiang Donald Grierson Yunbo Luo Wei Shen Silin Zhong Da-Qi Fu Guiqin Qu | 2019 | Horticulture Research2019，6，1： | 7 |
| 14 | Short-term effects of di-(2-ethylhexyl) phthalate on testes,liver, kidneys and pancreas in mice显示文摘瞄准:决定 di-(2-ethylhexyl ) 的生物化学的效果在生精的上皮的退化的过程的白天 10 上的睾丸,肝,肾和胰上的 phthalate (DEHP ) 。方法:包含 2% DEHP 的食谱被给男 Crlj : CD1 (ICR ) 老鼠 for10 天。DEHP 的剂量是 0.90 ± 0.52 mg/mouse/day。他们的睾丸,肝,肾 andpancreata 为察觉被检验单音 --(2-ethylhexyl ) phthalate (MEHP ) ,氮氧化物(NOx ) 生产了由每氮的氧化物的氧化(没有) 与自由激进分子,和类脂化合物一起每自由激进分子的链反应导致的氧化。结果:组织学的观察和浆液分析显示出严重 spermatogenic 骚乱, Leydig 房间机能障碍,肝机能障碍和脱水的存在。出人意料地,在睾丸的 MEHP 的集中在肝与那相比是极其低的。然而,在睾丸的 NOx 的集中象肝的集中一样高。而且,免费导致激进分子的类脂化合物组织化学地在睾丸然而并非在肝每氧化被检测。结论:结果显示阴囊的纸巾的高敏感引起到传播 MEHP 的 MEHP 而非特定的累积或举起进睾丸的那导致 DEHP 的 aspermatogenesisis。 | Yumi Miura Munekazu Naito Maira Ablake Hayato Terayama Shuang-Qin Yi Ning Qu Lin-Xian Cheng Shigeru Suna Fumihiko Jitsunari Masahiro Itoh | 2007 | Asian Journal of Andrology2007，9，2： | 6 |
| 15 | Recurrence Characteristics of Major Earthquakes in the Tangshan area,North China显示文摘Tangshan 区域躺在一位女士 7.8 地震发生在 1976 的北方中国平原,它与一个隐藏的活跃差错被联系。为了揭示专业的复发特征,在一相对长的时间在这个区域震动,我们用地质的调查,浅地震探索,地上凿穿,沟观察并且地质的标明日期进行了全面研究。五 paleoearthquakes 向西在一条 6.4m-deep 沟被认出到 Tangshan 精神病院。在他们之中,前者三个事件发生在 56.78 敮之间? | LIU Kang QU Guosheng CHEN Jianqiang WANG Weiguo NING Baokun | 2013 | Acta Geologica Sinica(English Edition)2013，87，1： | 5 |
| 16 | Eronchiectasis Management in China, What We Can Learn from European Respiratory Society Guidelines显示文摘 | Ning Wang Jie-Ming Qu Jin-Fu Xu | 2018 | Chinese Medical Journal2018，，16： | 5 |
| 17 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 18 | Synthesis and Characterization of Fluorinated Polyurethane Containing Carborane in the Main Chain: Thermal, Mechanical and Chemical Resistance Properties显示文摘In this study, two fluorinated polyurethanes(FPU) containing carborane groups in the main chains were firstly designed and synthesized via the reaction of hexamethylene diisocyanate trimer(HDI trimer) with fluorinated polyesters(CFPETs) having hydroxyl-terminated carborane groups at room temperature. The structures of carborane fluorinated polyesters(CFPETs) and polyurethanes(CFPUs) were characterized by gel permeation chromatography(GPC), Fourier transform infrared(FTIR) spectroscopy and nuclear magnetic resonance(NMR) measurements. The thermal stability, mechanical properties, Shore A hardness, solvent resistance and acid-alkali resistance of the carborane fluorinated polyurethane films were also studied. Thermogravimetric analysis(TGA) tests manifested that the introduction of carborane groups into the main chain of fluorinated polyurethane endowed the obtained fluorinated polyurethane with excellent thermal stability. The thermal decomposition temperature of carborane fluorinated polyurethane(CFPU) increased by 190 °C compared with that of the carborane-free fluorinated polyurethane(FPU). Even at 800 °C, CFPU showed the char yield of 66.5%, which was higher than that of FPU(34.3%). The carborane-containing fluorinated polyurethanes also showed excellent chemical resistance and prominent mechanical property even after the cured films being immersed into Jet aircraft oil or 37% HCl for 168 h or at high temperature(700 °C). It is found that the structural characteristics of carborane group and the compacted structure of CFPU effectively improve the thermal stability, mechanical property, solvent resistance and acid-alkali resistance of the carborane-free fluorinated polyurethane. These excellent properties make CFPU as the useful raw materials to prepare the high temperature resistant coatings or adhesives for automotive engines, engine or fuel tank of aircraft and other equipment working in high-temperature or high concentrations of acid-alkali environments. | Ning Li Fang-Lei Zeng Yu Wang De-Zhi Qu Chun Zhang Juan Li Jin-Zhao Huo Yong-Ping Bai | 2018 | Chinese Journal of Polymer Science2018，36，1： | 4 |
| 19 | Influences of different time intervals between loop electrosurgical excision and abdominal hysterectomy or radical hysterectomy on postoperative complications: a retrospective analysis显示文摘Objective:To study the influences of different time intervals between loop electrosurgical excision (LEEP) and abdominal hysterectomy or radical hysterectomy on postoperative complications. Methods:Sixty-eight patients, who received subsequent abdominal hysterectomy or radical hysterectomy after LEEP due to CIN Ⅲ and cervical cancer (IA1, IA2 and IB1), were included in the present study. The hospital and clinic records of these patients were reviewed. The patients were divided into three groups according to the time intervals between LEEP and hysterectomy or radical hysterectomy: group 1(within 48 h), group 2 (between 48 h to 6 weeks), and group 3(> 6 weeks ).Results: General characteristics of patients, including the mean age, delivery history, BMI, menopausal status, clinical stage and HPV infection, were comparable between patients of different groups. There were no significant differences in the mean transfusion amount, posthysterectomy hospital stay or operation time between different groups. The frequencies and spectrum of complications were not significantly affected by the time interval between LEEP and hysterectomy or radical hysterectomy. Conclusion: It is concluded that whenever the LEEP is done, the operation including hysterectomy or radical hysterectomy can be conducted at any time as it is necessary for the patients. | Qu Haina Zhang Yan Zhang Junjie Hui Ning Xu Mingjuan | 2010 | Journal of Medical Colleges of PLA(China)2010，25，1： | 4 |
| 20 | Purification function of the natural wetland in the Liaohe Delta显示文摘1IntroductionStructure,functionandchangearethreeimportantaspectsoflandscapeecology(Forman,1986).Landscapefunctionmeanstheinte... | Li Xiu Zhen, Qu Xiang rong, Wang Lian ping, Zhang Hai rong, Xiao Du ning Institute of Applied Ecology, Chinese Academy of Sciences, B.O. Box 417, Shengyang 110015, China | 1999 | Journal of Environmental Sciences1999，11，2： | 4 |
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