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| 1 | 保存大豆种质遗传完整性的策略:Ⅰ细化表型分级标准精细整理大豆库存种质显示文摘以中国大豆种质资源在美国的种植调查数据为资料,并与中国的调查数据进行比较,旨在研究大豆种质的遗传完整性,为中国大豆资源的繁种保存策略提供参考。中国大豆种质资源2093份在美国利用不同的调查标准进行农艺性状重新鉴定评价,30%的中国大豆种质资源可进一步分为不同的纯系,使种质的数量增加到3062份。以纯化后种质份数增加到9份的资源ZDD4572为例,对其纯化过程进行了详细分析。研究表明,现有的大豆资源在纯合保存前提下,用更多的评价性状、每个性状划分更多的等级,将有助于大豆种质资源的纯化及其数量的增加,从而更方便繁种和实际利用。 | 闫龙 Nelson R L 常汝镇 邱丽娟 | 2010 | 植物遗传资源学报2010，11，6： | 4 |
| 2 | Neonatal vitamin A injection promotes cattle muscle growth and increases oxidative muscle fibers显示文摘Background: Vitamin A and its metabolite,retinoic acid(RA),are important regulators of cell differentiation and organ morphogenesis.Its impact on beef cattle muscle growth remains undefined.Method: Angus steer calves were administrated with 0(control) or 150,000 IU vitamin A(retinyl palmitate in glycerol,i.m.) per calf at birth and 1 month of age.At 2 months of age,a biopsy of the Biceps femoris muscle was obtained to analyze the immediate effects of vitamin A injection on myogenic capacity of muscle cells.The resulting steers were harvested at 14 months of age.Results: Vitamin A administration increased cattle growth at 2 months.At 2 months of age,Vitamin A increased PAX7 positive satellite cells and the expression of myogenic marker genes including PAX7,MYF5,MYOD and MYOG.Muscle derived mononuclear cells were further isolated and induced myogenesis in vitro.More myotubes and a higher degree of myogenesis was observed in vitamin A groups.Consistently,vitamin A increased Latissimus dorsi(LD) muscle fiber size at harvest.In addition,vitamin A increased the ratio of oxidative type I and type IIA fibers and reduced the glycolic type IIX fibers.Furthermore,we found that RA,a key bioactive metabolite of vitamin A,activated PPARGC1 A promoter,which explains the upregulated expression of PPARGC1 A in skeletal muscle.Conclusion: Vitamin A administration to neonatal calves enhanced postnatal muscle growth by promoting myogenesis and increasing satellite cell density,accompanied with a shift to oxidative muscle fibers. | Bo Wang Wei Nie Xing Fu Jeanene M de Avila Yannan Ma Mei-Jun Zhu Martin Maquivar Steven M Parish Jan R Busboom Mark L Nelson Min Du | 2019 | Journal of Animal Science and Biotechnology2019，10，1： | 3 |
| 3 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 4 | Delay of disease development in transgenic plant that express the tobacco mosaic virus coat protein gene显示文摘 | Powell A P Nelson R S De B | 1986 | Science1986，232，： | 2 |
| 5 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘 | Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney | 2007 | AIDS2007，，10： | 2 |
| 6 | Microstructural investigation of friction stir welded 7050-T651 aluminium显示文摘 | J.-Q Su T.W Nelson R Mishra M Mahoney | 2002 | Acta Materialia2002，，3： | 2 |
| 7 | Soil moisture: A central and unifying theme in physical geography显示文摘 | Legates David R Mahmood Rezaul Levia Delphis F DeLiberty Tracy L Quiring Steven M Houser Chris Nelson Frederick E | 2011 | Progress in Physical Geography2011，，1： | 2 |
| 8 | Microstructural investigation of friction stir welded 7050-T651 aluminium显示文摘 | J.-Q Su T.W Nelson R Mishra M Mahoney | 2002 | Acta Materialia2002，，3： | 2 |
| 9 | Improved vertical resolution of well logs by resolution matching显示文摘 | Nelson R J Mitchell W K | 1992 | The Log Analyst1992，32，4： | 1 |
| 10 | The effect of non-normality on the control limits of X charts 显示文摘 | Schilling E G Nelson P R | 1976 | Journal of Quality Technology1976，8，2： | 1 |
| 11 | The persistence and degradation of chlorothalonil and chlorpyrifos in a cranberry bog 显示文摘 | Putnam R A Nelson J O Clark J M | 2003 | Agric Food Chem2003，51，： | 1 |
| 12 | The simple economics of basic scientific research 显示文摘 | Nelson R R | 1959 | The Journal of Political Economy1959，67，： | 1 |
| 13 | Obstructive sleep apnoea in children mig-ht impair cognition and behaviour显示文摘 | NELSON R | 2002 | Lancet2002，359，： | 1 |
| 14 | The role of hepatitis C virus-specific cytotoxic T-lymphocytes in chronic hepatitis C显示文摘 | Marousis C G Davis G L | 1997 | J Immunol1997，158，： | 1 |
| 15 | Fuel cell systems efficient,flexible energy conversion for the 21st century显示文摘 | Von Spakovsky M R Nelson D J | 2001 | Proc IEEE2001，89，12： | 1 |
| 16 | Hepatic artery adjuvant chemotherapy for patients having resection or ablation of colorectal cancer metastatic to the liver显示文摘 | Nelson R Freels S | 2004 | Cochrane Database of Systemic Reviews2004，，00： | 1 |
| 17 | The growth of patenting and licensing by US universities:an assessment of the effects of Bayh - Dole Act of 1980显示文摘 | Mowery D Nelson R Sampat B Zicdonis A | 2001 | Research Policy2001，，30： | 1 |
| 18 | Mediation of seasonal testicular regression by apoptosis 显示文摘 | YOUNG K A NELSON R J | 2001 | Reproduction2001，122，5： | 1 |
| 19 | The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes and nomenclature显示文摘 | Nelson D R Kamataki T Waxman D J | 1993 | DNA Cell Biol1993，12，1： | 1 |
| 20 | Adaptations to environmental stresses显示文摘 | Hans J Bohnert Nelson D E Jensen R G | 1995 | Plant cell1995，7，： | 1 |
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