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| 1 | Caffeine therapy in preterm infants显示文摘Caffeine is the most commonly used medication for treatment of apnea of prematurity. Its effect has been well established in reducing the frequency of apnea, intermittent hypoxemia, and extubation failure in mechanically ventilated preterm infants. Evidence for additional short-term benefits on reducing the incidence of bronchopulmonary dysplasia and patent ductus arteriosus has also been suggested. Controversies existamong various neonatal intensive care units in terms of drug efficacy compared to other methylxanthines, dosage regimen, time of initiation, duration of therapy, drug safety and value of therapeutic drug monitoring. In the current review, we will summarize the available evidence for the best practice in using caffeine therapy in preterm infants. | Hesham Abdel-Hady Nehad Nasef Abd Elazeez Shabaan Islam Nour | 2015 | World Journal of Clinical Pediatrics2015，4，4： | 25 |
| 2 | 源于近端股骨间充质干细胞免疫抑制作用的研究显示文摘目的探讨源于成人近端股骨的间充质干细胞(MSC)是否具有免疫抑制功能,为临床移植物抗宿主病的防治寻找理想的细胞储备库。方法从全髋关节置换术患者的近端股骨中分离并培养MSC,将不同数量的细胞直接或以Transwell法加入混合淋巴细胞反应(MLR)中,检测MSC对外周血淋巴细胞(PBL)增殖水平的影响。以ELISA法及抗体中和法探讨细胞因子TGFβ1在MSC免疫调节中的作用。结果3×103、1×104、3×104、1×105个源于近端股骨的MSC对PBL增殖的抑制率分别为62%±18%、38%±4%、31%±16%、28%±12%,与采自髂骨骨髓穿刺物MSC的抑制作用相比差异无统计学意义(均P>0.05),后者对PBL的增殖抑制率为58%±12%、37%±8%、28%±6%、27%±6%;以0.2μm的微孔膜对MSC与MLR进行分隔,3×104及1×104个MSC对PBL的增殖抑制率为36%±8%和53%±12%;在ELISA实验中,MSC单独培养,MSC与MLR直接接触,或经Transwell共培养的这3种上清中转化生长因子(TGF)β1的表达水平差异无统计学意义,加入浓度递增的TGFβ1抗体不能逆转MSC对PBL增殖的抑制作用。结论源于近端股骨的MSC具有一定的免疫抑制功能,除TGFβ1外其他可溶性因子可能介导这一作用。 | 张翼鷟 Loic Fouillard Alain Chapel Morad Bensidhoum Christelle Mazurier Aish Nasef Sandrine Bouchet Manuel Lopez Dominique Thierry Norbert Cclaucle Gorin 达万明 | 2005 | 中华医学杂志2005，85，39： | 11 |
| 3 | RADIATION GRAFTED POLY(VINYLIDENE FLUORIDE)-GRAFT-POLYSTYRENE SULFONIC ACID MEMBRANES FOR FUEL CELLS:STRUCTURE-PROPERTY RELATIONSHIPS显示文摘结构性质关系为(vinylidene 氟化物) poly,酸性硫酸基的酸(PVDF-g-PSSA ) 燃料房间膜由包含钠苯乙烯 sulfonate (SSS ) 的导致放射的 grafting 到电子横梁(EB ) 上 poly 照耀的一个单个步方法(vinylidene 氟化物)(PVDF ) 准备了的 -graft-polystyrene 拍摄被建立。象离子交换能力,水胀大和质子电导率那样的膜的物理化学的性质与 grafting 的学位被相关(G, %) 并且在准备过程期间发生在膜矩阵的结构的变化。在 crystallinity 和膜的热稳定性的变化被微分扫描热量测定(DSC ) 和 thermogravimetric 分析(TGA ) 分别地学习。膜被发现经历实质的结构的变化处于良好的竟技状态离子的地点,增加, hydrophilicity 改进, hydrophobicity 减小和 crystallinity 在 G (%) 和准备方法与变化减少。获得的膜的结构、热的性质也与他们一个常规二拍子的圆舞方法准备的对应物相比即放射导致了苯乙烯的 grafting 到照耀的 PVDF 电影由 sulfonation 跟随了的 EB 上。一个单个步的方法获得的 PVDF-g-PSSA 膜被发现与常规二拍子的圆舞方法获得的那些相比有优异性质。关键词 PVDF 电影 - 钠苯乙烯 sulfonate - 导致放射的 grafting - | Mohamed Nasef Hamdani Saidi Khairulzaman Mohd Dahlan | 2010 | Chinese Journal of Polymer Science2010，28，5： | 3 |
| 4 | Electrospinning of Nylon-6,6 Solutions into Nanofibers: Rheology and Morphology Relationships显示文摘The relationship between the rheological properties of nylon-6,6 solutions and the morphology of their electrospun nanofibers was established. The viscosity of nylon-6,6 in formic acid(90%) was measured in the concentration range of 5 wt%-25 wt% using a programmable viscometer. Electrospinning of nylon-6,6 solutions was carried out under controlled parameters. The chemical structure, morphology and thermal properties of the obtained nanofibers were investigated using Fourier transform infrared spectroscopy(FTIR), scanning electron microscopy(SEM) and differential scanning calorimetry(DSC), respectively. Entanglement concentration(ce) was found to be 15 wt% and a power law relationship between specific viscosity and solution concentration was observed with exponents of 2.0 and 3.3 for semi-dilute unentangled(c < ce) and semi-dilute entangled(c > ce) regimes, respectively. The diameter and uniformity of the nanofibers were found to be dependent on the viscosity. Moreover, the average diameter of electrospun nanofibers was found to be dependent on zero shear rate viscosity and normalized concentration(c/ce) in a power law relationship with exponents of 0.298 and 0.816, respectively. For nylon-6,6 solutions, the entanglement concentration(ce = 15 wt%) provides the threshold viscosity required for the formation of a stable polymeric jet during electrospinning and producing uniform beadless fibers. For concentrations less than ce, beaded fibers with some irregularities are formed. DSC analysis showed an increase in crystallinity of all electrospun samples compared to original polymer. Furthermore, Based on FTIR spectroscopy, α phase is dominant in electrospun nanofibers and minor amount of β and γ phases is also available. | Ali Abbasi Mohamed Mahmoud Nasef Matsuura Takeshi Reza Faridi-Majidi | 2014 | Chinese Journal of Polymer Science2014，32，6： | 2 |
| 5 | Preparation and applications of ion exchange membranes by radiation-induced graft copolymerization of polar monomers onto non-polar films显示文摘 | NASEF M M HEGAZY E | 2004 | Progress in Polymer Science2004，29，： | 1 |
| 6 | Investigation of electron irradiation induced-changes in poly(vinylidene fluoride)films显示文摘 | NASEF M M SAIDI H DAHLAN K Z M | 2002 | Polymer Degradation and Stability2002，75，： | 1 |
| 7 | Immunomodulatory effect of mesenchymal stromal cells:possible mechanisms显示文摘 | Nasef A Fouillard L Ashammakhi N | 2008 | RegenMed2008，3，4： | 1 |
| 8 | High - flow nasal cannulae are associated with increased diaphragm activation compared with nasal continuous positive airway pressure in preterm infants 显示文摘 | Nasef N El - Gouhary E Schurr P | 2015 | Acta Paediatr2015，104，8： | 1 |
| 9 | Identification of IL-10 and TGF-beta transcripts involved in the inhibition of T-lymphocyte proliferation during cell contact with human mesenehymal stem ceils 显示文摘 | Nasef A Chapel A Mazurier C | 2007 | Gene Expr2007，13，： | 1 |
| 10 | Identification of IL- 10 and TGF-beta transcripts involved in the inhibition of T- lymphocyte proliferation during cell contact with human mesenchymal stem cells 显示文摘 | Nasef A Chapel A Mazurier C | 2007 | Gene Expr2007，13，45： | 1 |
| 11 | PSSA pore-filled PVDF membranes by simultaneous electron beam irradiation:preparation and transport characteristics of protons and methanol显示文摘 | NASEF M M ZUBIR Z A ISMAILA F | 2006 | J Memb Sci2006，268，： | 1 |
| 12 | Preparation of radiochemically pore-filled polymer electrolyte membranes for direct methanol fuel cells显示文摘 | Nasef M M Zubir N A Ismail A F | 2006 | J Power Sources2006，156，： | 1 |
| 13 | Kinetic investigations of graft copolymerization of sodium styrene sulfonate onto electron beam irradiated poly(vinylidene fluoride) films显示文摘 | NASEF M M SAIDI H DAHLAN K Z M | 2011 | Radiation Physics and Chemistry2011，80，： | 1 |
| 14 | Immunomodulatory effect of mesenchymal stromal cells:possible mechanisms显示文摘 | NASEF A ASHAMMAKHI N FOUILLARD L | 2008 | Regen Med2008，3，4： | 1 |
| 15 | Radiation graf- ted poly (ethylene terephthalate) -graft-polystyrene pervapo- ration membranes for organic/organic separation 显示文摘 | KHAYET M NASEF M M MENGUAL J I | 2005 | J Membr Sci2005，263，： | 1 |
| 16 | Preparation and applications of ion exchange membranes by radiation-induced graft copolymeriza- tion of polar monomers onto non-polar films 显示文摘 | Nasef M M Hegazy E-SA | 2004 | Prog Polym Sei2004，29，6： | 1 |
| 17 | Inflammatory bowel disease and pregnancy: overlapping pathways显示文摘 | Noha Ahmed Nasef Lynnette R. Ferguson | 2012 | Translational Research2012，，1： | 1 |
| 18 | Immunomodulatory ef-fect of mesenchymal stromal cells: possible mechanisms显示文摘 | Nasef A Ashammakhi N Fouillard L | 2008 | Regen Med2008，3，4： | 1 |
| 19 | Identification of IL-IO and TGF -beta transcripts involved in the inhibition of T -lymphocyte pro?liferation during cell contact with human mesenchymal stem cells 显示文摘 | Nasef A Chapel A Mazurier C | 2007 | Gene Expr2007，13，： | 1 |
| 20 | Immunosuppressive Effects of Mesenchymal Stem Cells: Involvement of HLA-G显示文摘 | Aisha Nasef Noelle Mathieu Alain Chapel Johanna Frick Sabine Fran?ois Christelle Mazurier Asma Boutarfa Sandrine Bouchet N-Claude Gorin Dominique Thierry Lo?c Fouillard | 2007 | Transplantation2007，，2： | 1 |
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