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| 1 | 鱼尼丁受体类杀虫剂的研究进展显示文摘介绍了鱼尼丁受体类新型杀虫剂的创制现状、作用机制、生物活性、毒性及合成方法,由于此类杀虫剂的结构独特、作用方式新颖、对鳞翅目害虫效果好、杀虫广谱,该类药剂对各种益虫和天敌安全,对现用的杀虫剂无交互抗性,具有良好的发展前景. | 王唤 米娜 范志金 Natalia P Belskaia Vasiliy A Bakulev | 2011 | 四川师范大学学报(自然科学版)2011，34，3： | 10 |
| 2 | Genomic prediction of the performance of hybrids and the combining abilities for line by tester trials in maize显示文摘The two most important activities in maize breeding are the development of inbred lines with high values of general combining ability(GCA)and specific combining ability(SCA),and the identification of hybrids with high yield potentials.Genomic selection(GS)is a promising genomic tool to perform selection on the untested breeding material based on the genomic estimated breeding values estimated from the genomic prediction(GP).In this study,GP analyses were carried out to estimate the performance of hybrids,GCA,and SCA for grain yield(GY)in three maize line-by-tester trials,where all the material was phenotyped in 10 to 11 multiple-location trials and genotyped with a mid-density molecular marker platform.Results showed that the prediction abilities for the performance of hybrids ranged from 0.59 to0.81 across all trials in the model including the additive effect of lines and testers.In the model including both additive and non-additive effects,the prediction abilities for the performance of hybrids were improved and ranged from 0.64 to 0.86 across all trials.The prediction abilities of the GCA for GY were low,ranging between-0.14 and 0.13 across all trials in the model including only inbred lines;the prediction abilities of the GCA for GY were improved and ranged from 0.49 to 0.55 across all trials in the model including both inbred lines and testers,while the prediction abilities of the SCA for GY were negative across all trials.The prediction abilities for GY between testers varied from-0.66 to 0.82;the performance of hybrids between testers is difficult to predict.GS offers the opportunity to predict the performance of new hybrids and the GCA of new inbred lines based on the molecular marker information,the total breeding cost could be reduced dramatically by phenotyping fewer multiple-location trials. | Ao Zhang Paulino Pérez-Rodríguez Felix San Vicente Natalia Palacios-Rojas Thanda Dhliwayo Yubo Liu Zhenhai Cui Yuan Guan Hui Wang Hongjian Zheng Michael Olsen Boddupalli M.Prasanna Yanye Ruan Jose Crossa Xuecai Zhang | 2022 | The Crop Journal2022，10，1： | 3 |
| 3 | CD4+ T cells and natural killer cells: Biomarkers for hepatic fibrosis in human immunodeficiency virus/hepatitis C virus-coinfected patients显示文摘AIM To characterize peripheral blood natural killer(NK) cells phenotypes by flow cytometry as potential biomarker of liver fibrosis in human immunodeficiency virus(HIV)/hepatitis C virus(HCV) coinfected patients.METHODS Peripheral mononuclear cells from 24 HIV/HCV(HBVnegative) coinfected and 5 HIV/HCV/HBV seronegative individuals were evaluated. HIV/HCV coinfected patients were divided in to groups: G1, patients with METAVIR F0-F2 and G2, patients with METAVIR F3-F4. NK surface cell staining was performed with: AntiCD3(APC/Cy7), anti-CD56(PE/Cy5), anti-CD57(APC), anti-CD25(PE), anti-CD69(FITC), anti-NKp30(PE), antiNKp46(PE/Cy7), anti-NKG2D(APC), anti-DNAM(FITC); anti-CD62L(PE/Cy7), anti-CCR7(PE), anti-TRAIL(PE), anti-Fas L(PE), anti CD94(FITC). Flow cytometry data acquisition was performed on BD FACSCanto, analyzed using Flow Jo software. Frequency of fluorescence was analyzed for all single markers. Clinical records were reviewed, and epidemiological and clinical data were obtained.RESULTS Samples from 11 patients were included in G1 and from 13 in G2. All patients were on ARV, with undetectable HIV viral load. Liver fibrosis was evaluated by transient elastography in 90% of the patients and with biopsy in 10% of the patients. Mean HCV viral load was(6.18 ± 0.7 log10). Even though, no major significant differences were observed between G1 and G2 regarding NK surface markers, it was found that patients with higher liver fibrosis presented statistically lower percentage of NK cells than individual with low to mild fibrosis and healthy controls(G2: 5.4% ± 2.3%, G1: 12.6% ± 8.2%, P = 0.002 and healthy controls 12.2% ± 2.7%, P = 0.008). It was also found that individuals with higher liver fibrosis presented lower CD4 LT count than those from G1(G2: 521 ± 312 cells/μL, G1: 770 ± 205 cells/μL; P = 0.035).CONCLUSION Higher levels of liver fibrosis were associated with lower percentage of NK cells and LTCD4+ count; and they may serve as noninvasive biomarkers of liver damage. | Natalia Laufer Diego Ojeda María Laura Polo Ana Martinez Héctor Pérez Gabriela Turk Pedro Cahn Norberto Walter Zwirner Jorge Quarleri | 2017 | World Journal of Hepatology2017，9，25： | 2 |
| 4 | Omentum facilitates liver regeneration显示文摘AIM:To investigate the mechanism of liver regeneration induced by fusing the omentum to a small traumatic injury created in the liver. We studied three groups of rats. In one group the rats were omentectomized; in another group the omentum was left in situ and was not activated,and in the third group the omentum was activated by polydextran particles. METHODS:We pre-activated the omentum by injecting polydextran particles and then made a small wedge wound in the rat liver to allow the omentum to fuse to the wound. We monitored the regeneration of the liver by determining the ratio of liver weight/body weight,by histological evaluation (including immune staining for cytokeratin-19,an oval cell marker),and by testing for developmental gene activation using reverse transcription polymerase chain reaction (RT-PCR). RESULTS:There was no liver regeneration in the omentectomized rats,nor was there significant regeneration when the omentum was not activated,even though in this instance the omentum had fusedwith the liver. In contrast,the liver in the rats with the activated omentum expanded to a size 50% greater than the original,and there was histologically an interlying tissue between the wounded liver and the activated omentum in which bile ducts,containing cytokeratin-19 positive oval cells,extended from the wound edge. In this interlying tissue,oval cells were abundant and appeared to proliferate to form new liver tissue. In rats pre-treated with drugs that inhibited hepatocyte growth,liver proliferation was ongoing,indicating that regeneration of the liver was the result of oval cell expansion. CONCLUSION:Activated omentum facilitates liver regeneration following injury by a mechanism that depends largely on oval cell proliferation. | Ashok K Singh Nishit Pancholi Jilpa Patel Natalia O Litbarg Krishnamurthy P Gudehithlu Perianna Sethupathi Mark Kraus George Dunea Jose AL Arruda | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 5 | Quantitative determination of hippuric and benzoic acids in mine by LC - MS/MS using surrogate standards 显示文摘 | Natalia P Penner Ragu R Joanna ZP | 2010 | J Pharmacet Biomed Anal2010，，52： | 1 |
| 6 | Evaluation of seven housekeeping genes for multilocus sequence analysis of the genus Mesorhizobium : resolving the taxonomic affiliation of the Cicer canariense rhizobia显示文摘 | Juan Pérez-Yépez Natalia Armas-Capote Encarna Velázquez Ricardo Pérez-Galdona Raúl Rivas Milagros León-Barrios | 2014 | Systematic and Applied Microbiology2014，，： | 1 |
| 7 | DNA extraction from several cacti显示文摘 | Candelario M J Natalia D Bruce P B | 2000 | Hort Science2000，35，6： | 1 |
| 8 | Probing the genetic population structure of Trypanosoma cruzi with polymorphic microsatellites显示文摘 | Broude Natalia E Macedo Andrea M | 1998 | Proceedings of the National Academy of Sciences of the United States of America1998，95，7： | 1 |
| 9 | Effect of light quality on the organization of photosynthetic electron trans port chain of pea seedlings 显示文摘 | Natalia P V Inna S D Krendeleva Ta E | 1977 | Plant Physiology1977，59，： | 1 |
| 10 | Recovery of valuable elements from spent Li-batteries 显示文摘 | JESSICA F P NATALIA G B JLrLIO C A | 2008 | Journal of Hazardous Materi- als2008，150，： | 1 |
| 11 | Determination of coumaphos, chlorpyrifos and ethion residues in propolis tinctures by matrix solid-phase dispersion and gas chromatography coupled to flame photometric and mass spectrometric detection显示文摘 | Andrés Pérez-Parada Marcos Colazzo Natalia Besil Lucía Geis-Asteggiante Federico Rey Horacio Heinzen | 2011 | Journal of Chromatography A2011，，34： | 1 |
| 12 | Phenanthrene metabolism by Pseudomonas and Burkholderia strains显示文摘 | Natalia V Balashova Irina A Koshelava Nicolai P | 1999 | Process Biochemistry1999，35，： | 1 |
| 13 | Severe acute respiratory syndrome (SARS) S protein production in plants : development of recombinant vaccine 显示文摘 | NATALIA P MAXIM G VYACHESLAV A | 2005 | PNAS2005，102，25： | 1 |
| 14 | A practical synthetic approach to chiral α-aryl substituted ethylphosphonates 显示文摘 | Natalia S Goulioukina Tatyana M Dolgina Irina P Beletskaya | 2001 | Tetrahedron : Asymmetry2001，12，2： | 1 |
| 15 | Nitric oxide inhibits mitochondrial movement in forebrain neurons as- sociated with disruption of mitochondrial membrane potential显示文摘 | Gordon L R Vicki J B Natalia A P | 2006 | Journal of Neurochemistry2006，97，： | 1 |
| 16 | DNA extraction from several cacti显示文摘 | Candelario M J Natalia D Bruce P B | 2000 | Hort Science2000，35，6： | 1 |
| 17 | High serum levels of pro-brain natriuretic peptide (pro BNP) identify cardioembolic origin in undetermined stroke显示文摘 | Manuel Rodríguez-Yá?ez Tomás Sobrino Miguel Blanco Natalia Pérez de la Ossa David Brea Raquel Rodríguez-González Rogelio Leira Antonio Dávalos José Castillo | 2009 | Disease Markers2009，，4： | 1 |
| 18 | Supercritical fluid extraction of grape seed:process scale-up,extract chemical composition and economic evaluation显示文摘 | Juliana M P Irede D Natalia D D | 2012 | Journal of Food Engineering2012，109，： | 1 |
| 19 | Applications of ionic liquids in the chemical industry 显示文摘 | Natalia V P Kenneth R S | 2008 | Chemical Society Reviews2008，37，： | 1 |
| 20 | Iron-Related Brain Damage in Patients With Intracerebral Hemorrhage显示文摘 | Natalia P Toma S Yolanda S | 2010 | Stroke2010，41，2： | 1 |
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