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| 1 | Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD显示文摘AIM: To detect a possible association between the polymorphism of the (-670 A/G) Fas/Apo1 gene promoter and susceptibility to Crohn's disease (CD) and ulcerative colitis (UC) in the Tunisian population. METHODS: The (-670 A/G) Fas polymorphism was analyzed in 105 patients with CD, 59 patients with UC, and 100 controls using the polymerase chain reaction restriction fragment length polymorphism method. RESULTS: Significantly lower frequencies of the Fas -670 A allele and A/A homozygous individuals were observed in CD and UC patients when compared with controls. Analysis of (-670 A/G) Fas polymorphism with respect to sex in CD and UC showed a significant difference in A/A genotypes between female patients and controls (P corrected = 0.004 in CD patients and P corrected = 0.02 in UC patients, respectively). Analysis also showed a statistically significant association between genotype AA of the (-670 A/G) polymorphism and the ileum localization of the lesions (P corrected = 0.048) and between genotype GG and the colon localization (Pcorrected = 0.009). The analysis ofinflammatory bowel disease patients according to clinical behavior revealed no difference. CONCLUSION: Fas-670 polymorphism was associated with the development of CD and UC in the Tunisian population. | Walid Ben Aleya Imen Sfar Leila Mouelhi Houda Aouadi Mouna Makhlouf Salwa Ayed-Jendoubi Samira Matri Azza Filali Taoufik Najjar Taeib Ben Abdallah Khaled Ayed Yousr Gorgi | 2009 | World Journal of Gastroenterology2009，15，29： | 3 |
| 2 | Modeling superheat removal during continuous casting of steel slabs显示文摘 | Huang X Thomas B G Najjar F M | 1992 | Metall Trans B1992，23，： | 2 |
| 3 | Influence of critical surface defects and localized competition between anodic dissolution and hydrogen effects during stress corrosion cracking of a 7050 aluminium alloy显示文摘 | D Najjar T Magnin T.J Warner | 1997 | Materials Science & Engineering A1997，，2： | 2 |
| 4 | Novel predictors of permanent pacemaker implantation following transcatheter aortic valve replacement显示文摘BACKGROUND Conduction and rhythm abnormalities requiring permanent pacemakers(PPM)are short-term complications following transcatheter aortic valve replacement(TAVR),and their clinical outcomes remain conflicting.Potential novel predictors of post-TAVR PPM,like QRS duration,QTc prolongation,and supraventricular arrhythmias,have been poorly studied.AIM To evaluate the effects of baseline nonspecific interventricular conduction delay and supraventricular arrhythmia on post-TAVR PPM requirement and determine the impact of PPM implantation on clinical outcomes.METHODS RESULTS Out of the 357 patients that met inclusion criteria,the mean age was 80 years,188(52.7%)were male,and 57(16%)had a PPM implantation.Baseline demographics,valve type,and cardiovascular risk factors were similar except for type II diabetes mellitus(DM),which was more prevalent in the PPM cohort(59.6%vs 40.7%;P=0.009).The PPM cohort had a significantly higher rate of pre-procedure right bundle branch block,prolonged QRS>120 ms,prolonged QTc>470 ms,and supraventricular arrhythmias.There was a consistently significant increase in the odds ratio(OR)of PPM implantation for every 20 ms increase in the QRS duration above 100 ms:QRS 101-120[OR:2.44;confidence intervals(CI):1.14-5.25;P=0.022],QRS 121-140(OR:3.25;CI:1.32-7.98;P=0.010),QRS 141-160(OR:6.98;CI:3.10-15.61;P<0.001).After model adjustment for baseline risk factors,the OR remained significant for type II DM(aOR:2.16;CI:1.18-3.94;P=0.012),QRS>120(aOR:2.18;CI:1.02-4.66;P=0.045)and marginally significant for supraventricular arrhythmias(aOR:1.82;CI:0.97-3.42;P=0.062).The PPM cohort had a higher adjusted OR of heart failure(HF)hospitalization(aOR:2.2;CI:1.1-4.3;P=0.022)and nonfatal myocardial infarction(MI)(aOR:3.9;CI:1.1-14;P=0.031)without any difference in mortality(aOR:1.1;CI:0.5-2.7;P=0.796)at one year.CONCLUSION Pre-TAVR type II DM and QRS duration>120,regardless of the presence of bundle branch blocks,are predictors of post-TAVR PPM.At 1-year post-TAVR,patients with PPM have higher odds of HF hospitalization and MI. | Somto Nwaedozie Haibin Zhang Javad Najjar Mojarrab Param Sharma Paul Yeung Peter Umukoro Deepa Soodi Rachel Gabor Kelley Anderson Romel Garcia-Montilla | 2023 | World Journal of Cardiology2023，15，11： | 2 |
| 5 | Influence of critical surface defects and localized competition between anodic dissolution and hydrogen effects during stress corrosion cracking of a 7050 aluminium alloy显示文摘 | D Najjar T Magnin T.J Warner | 1997 | Materials Science & Engineering A1997，，2： | 2 |
| 6 | Influence of critical surface defects and localized competition between anodic dissolution and hydrogen effects during stress corrosion cracking of a 7050 aluminum alloy 显示文摘 | Najjar D Magnin T Warner T J | 1997 | Mater Sci Eng A1997，238，2： | 2 |
| 7 | Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness, Predicts Cardiovascular Events in Well-Functioning Older Adults显示文摘 | Kim Sutton-Tyrrell Samer S. Najjar Robert M. Boudreau Lakshmi Venkitachalam Varant Kupelian Eleanor M. Simonsick Richard Havlik Edward G Lakatta Harold Spurgeon Stephen Kritchevsky Marco Pahor Douglas Bauer Anne Newman | 2005 | Circulation2005，，25： | 2 |
| 8 | Novel Design of Ring Resonator Based Temperature Sensor Using Photonics Technology显示文摘在现在的纸,我们学习二维的 photonic 水晶(PC ) 的传播 superellipse 戒指共鸣器。optomechanical 系统的快成长应用在新察觉到的机制导致强壮的要求以便设计察觉到的元素到纳米规模。photonic 水晶基于共鸣器因为乐队差距结构和共鸣器特征对变丑和在 PC 共鸣器的杆 / 洞的位置移动极其敏感,作为有希望的解决方案被调查了。这结构打开一个单个隧道过滤器。学习为与这结构的温度隧道过滤器波长调节被扩大。隧道过滤器的传播线性地与温度显示出红移动。隧道过滤器的这波长移动被用于传感器申请。为建议结构的敏感被发现是 65.3 pm/???????????????????????????? 乎吗?? | Mas soudi RADHOUENE Mayur Kumar CHHIPA Monia NAJJAR S. ROBINSON Bhuvneshwer SUTHAR | 2017 | Photonic Sensors2017，7，4： | 2 |
| 9 | Multi-photon microscopic evaluation of saphenous vein endothelium and its preservation with a new solution, GALA显示文摘 | Thatte HS Biswas KS Najjar SF | 2003 | Ann Thorac Surg2003，75，： | 1 |
| 10 | Nonlinear Water Diffusion in Nonsaturated Concrete显示文摘 | Bazant Z P Najjar L J | 1972 | Materal and Structure1972，5，1： | 1 |
| 11 | The water balance of the Susquehanna River basin and its response to climate change显示文摘 | NAJJAR R G 1999 | 1999 | Journal of Hydrology1999，219，： | 1 |
| 12 | Immunology and epilepsy显示文摘 | Najjar S Bembaum M Lai G | 2008 | Rev Neurol Dis2008，5，3： | 1 |
| 13 | Nonlinear water diffusion in nonsaturated con- crete显示文摘 | BAZANT Z NAJJAR I | 1972 | Materials and Structures1972，5，25： | 1 |
| 14 | Arterial aging and subelinical arterial disease are fundamentally interwined at macroscopic and molecular levels显示文摘 | Lakatta EG Wang M Najjar SS | 2009 | Med Clin North Am2009，93，3： | 1 |
| 15 | Numerical study of steady turbulent flow through bifurcated nozzles in continu- ous casting显示文摘 | Najjar F Thomas B Hershey D | 1995 | Metall Mater Trans B1995，26，4： | 1 |
| 16 | Arterial-ventricular coupling: mechanistic insights into cardiovascular performance at rest and during exercise显示文摘 | Chantler PD Lakatta EG Najjar SS | 2008 | J Appl Physiol ( 1985 )2008，105，4： | 1 |
| 17 | On the use of neural networks to evaluate groundwater levels in fractured media显示文摘 | Lallahem S Maniaa J Hani A Najjar Y | 2005 | Journal of Hydrology2005，307，： | 1 |
| 18 | The water balance of the Susquehanna River Basin and its response to climate change显示文摘 | NAJJAR R G | 1999 | Journal of Hydrology1999，219，： | 1 |
| 19 | Elevated aortic pulse wave velocity,a marker of arterial stiffness,predicts cardiovascular events in well-functioning older adults显示文摘 | Sutton-Tyrrell K Najjar SS Boudreau RM | 2005 | Circulation2005，111，25： | 1 |
| 20 | Increasing N abundance in the Northwestern Pacific Ocean due to atmospheric nitrogen deposi- tion显示文摘 | Kim T W Lee K Najjar R G | 2011 | Science2011，334，6055： | 1 |
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