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4篇 您的检索式:作者名="Azza Filali"
    题名 作者 年代 出处 被引量
1Association of Fas/Apo1 gene promoter (-670 A/G) polymorphism in Tunisian patients with IBD显示文摘AIM: To detect a possible association between the polymorphism of the (-670 A/G) Fas/Apo1 gene promoter and susceptibility to Crohn's disease (CD) and ulcerative colitis (UC) in the Tunisian population. METHODS: The (-670 A/G) Fas polymorphism was analyzed in 105 patients with CD, 59 patients with UC, and 100 controls using the polymerase chain reaction restriction fragment length polymorphism method. RESULTS: Significantly lower frequencies of the Fas -670 A allele and A/A homozygous individuals were observed in CD and UC patients when compared with controls. Analysis of (-670 A/G) Fas polymorphism with respect to sex in CD and UC showed a significant difference in A/A genotypes between female patients and controls (P corrected = 0.004 in CD patients and P corrected = 0.02 in UC patients, respectively). Analysis also showed a statistically significant association between genotype AA of the (-670 A/G) polymorphism and the ileum localization of the lesions (P corrected = 0.048) and between genotype GG and the colon localization (Pcorrected = 0.009). The analysis ofinflammatory bowel disease patients according to clinical behavior revealed no difference. CONCLUSION: Fas-670 polymorphism was associated with the development of CD and UC in the Tunisian population.Walid Ben Aleya Imen Sfar Leila Mouelhi Houda Aouadi Mouna Makhlouf Salwa Ayed-Jendoubi Samira Matri Azza Filali Taoufik Najjar Taeib Ben Abdallah Khaled Ayed Yousr Gorgi 2009World Journal of Gastroenterology2009,15,29:3
2Crohn?s disease and polymorphism of heat shock protein gene HSP70-2 in the Tunisian population显示文摘Lilia Zouiten-Mekki Sami Karoui Maher Kharrat Monia Fekih Samira Matri Jalel Boubaker Azza Filali Habiba Chaabouni 2007European Journal of Gastroenterology & Hepatology2007,,3:1
3Prevalence and risk factors of hyperhomocysteinemia in Tunisian patients with Crohn’s disease显示文摘Lamia Kallel Moncef Feki Wirak Sekri Lamia Segheir Monia Fekih Jalel Boubaker Naziha Kaabachi Azza Filali 2010Journal of Crohn’s and Colitis2010,,2:1
4Prevalence and risk factors of hyperhomocysteinemia in Tunisian patients with Crohn’s disease显示文摘Lamia Kallel Moncef Feki Wirak Sekri Lamia Segheir Monia Fekih Jalel Boubaker Naziha Kaabachi Azza Filali 2010Journal of Crohn’s and Colitis2010,,2:1
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