|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gastroparesis: Current diagnostic challenges and management considerations显示文摘Gastroparesis refers to abnormal gastric motility characterized by delayed gastric emptying in the absence of mechanical obstruction. The most common etiologies include diabetes, post-surgical and idiopathic. The most common symptoms are nausea, vomiting and epigastric pain. Gastroparesis is estimated to affect 4% of the population and symptomatology may range from little effect on daily activity to severe disability and frequent hospitalizations. The gold standard of diagnosis is solid meal gastric scintigraphy. Treatment is multimodal and includes dietary modification, prokinetic and anti-emetic medications, and surgical interventions. New advances in drug therapy, and gastric electrical stimulation techniques have been introduced and might provide new hope to patients with refractory gastroparesis. In this comprehensive review, we discuss gastroparesis with emphasis on the latest developments; from the perspective of the practicing clinician. | Shamaila Waseem Baharak Moshiree Peter V Draganov | 2009 | World Journal of Gastroenterology2009，15，1： | 71 |
| 2 | Predisposing factors for positive D-Xylose breath test for evaluation of small intestinal bacterial overgrowth:A retrospective study of 932 patients显示文摘AIM: To investigate, in the largest cohort to date, patient characteristics and associated risk factors for developing small intestinal bacterial overgrowth(SIBO) using the D-Xylose breath test(XBT).METHODS: We performed a retrospective crosssectional study to analyze patient characteristics who underwent the XBT for evaluation of SIBO. Diagnostic testing with the XBT was performed based on a clinical suspicion for SIBO in patients with symptoms of bloating, abdominal pain, abdominal distension, weight loss, diarrhea, and/or constipation. Consecutive electronicmedical records of 932 patients who completed the XBT at the University of Florida between 2005 and 2009 were reviewed. A two-way Analysis of Variance(ANOVA) was used to test for several associations including age, gender, and body mass index(BMI) with a +XBT. A two-way ANOVA was also performed to control for the differences and interaction with age and between genders. A similar analysis was repeated for BMI. Associations between medical conditions and prior surgical histories were conducted using the Mantel-Haenszel method for 2 by 2 contingency tables, stratified for gender. Reported odds ratio estimates reflect the odds of the prevalence of a condition within the +XBT group to that of the-XBT group. P values of less than 0.05(two-sided) were considered statistically significant.RESULTS: In the 932 consecutive eligible subjects studied, 513 had a positive XBT. A positive association was found between female gender and a positive XBT(P = 0.0025), and females with a positive test were, on average, greater than 5 years older than those with a negative test(P = 0.024). The mean BMI of positive XBT subjects was normal(24.5) and significantly lower than the subjects with a negative XBT(29.5)(P = 0.0050). A positive XBT was associated with gastroesophageal reflux disease(GERD)(OR = 1.35; 95%CI: 1.02-1.80, P = 0.04), peptic ulcer disease(PUD)(OR = 2.61; 95%CI: 1.48-4.59, P < 0.01), gastroparesis(GP)(OR = 2.04; 95%CI: 1.21-3.41, P < 0.01) and steroid use(OR = 1.35; 95%CI: 1.02-1.80, P = 0.01). Irritable bowel syndrome, independent protonpump inhibitor(PPI) usage, or previous abdominal surgery was not significantly associated with a positive XBT. No single subdivision by gender or PPI use was associated with a significant difference in the odds ratios between any of the subsets. CONCLUSION: Female gender, lower BMI, steroid use, PUD, GERD(independent of PPI use), and GP were more prevalent in patients with SIBO, determined by a positive XBT. Increasing age was associated with SIBO in females, but not in males. | Richard A Schatz Qing Zhang Nilesh Lodhia Jonathan Shuster Phillip P Toskes Baharak Moshiree | 2015 | World Journal of Gastroenterology2015，21，15： | 4 |
| 3 | Randomized, controlled trial of standard, large-capacity versus jumbo biopsy forceps for polypectomy of small, sessile, colorectal polyps显示文摘 | Peter V. Draganov Myron N. Chang Ahmad Alkhasawneh Lisa R. Dixon John Lieb Baharak Moshiree Steven Polyak Shahnaz Sultan Dennis Collins Amitabh Suman John F. Valentine Mihir S. Wagh Samir L. Habashi Chris E. Forsmark | 2012 | Gastrointestinal Endoscopy2012，，1： | 2 |
| 4 | Acid and non-acid reflux in patients refractory to proton pump inhibitor therapy:Is gastroparesis a factor?显示文摘AIM:To determine whether an increased number and duration of non-acid reflux events as measured using the multichannel intraluminal impedance pH(MII-pH)is linked to gastroparesis(GP).METHODS:A case control study was conducted in which 42 patients undergoing clinical evaluation for continued symptoms of gastroesophageal reflux disease(both typical and atypical symptoms)despite acid suppression therapy.MII-pH technology was used over 24 h to detect reflux episodes and record patients’symptoms.Parameters evaluated in patients with documented GP and controls without GP by scintigraphy included total,upright,and supine number of acid and non-acid reflux episodes(pH<4 and pH>4,respectively),the duration of acid and non-acid reflux in a 24-h period,and the number of reflux episodes lasting longer than 5 min.RESULTS:No statistical difference was seen between the patients with GP and controls with respect to the total number or duration of acid reflux events,total number and duration of non-acid reflux events or the duration of longest reflux episodes.The number of nonacid reflux episodes with a pH>7 was higher in subjects with GP than in controls.In addition,acid reflux episodes were more prolonged(lasting longer than 5min)in the GP patients than in controls;however,these values did not reach statistical significance.Thirty-five patients had recorded symptoms during the 24 h study and of the 35 subjects,only 9%(n=3)had a positive symptom association probability(SAP)for acid/non-acid reflux and 91%had a negative SAP.CONCLUSION:The evaluation of patients with a documented history of GP did not show an association between GP and more frequent episodes of non-acid reflux based on MII-pH testing. | Anna Tavakkoli Bisma A Sayed Nicholas J Talley Baharak Moshiree | 2013 | World Journal of Gastroenterology2013，19，37： | 2 |
| 5 | Peripheral and central contributions to hyperalgesia in irritable bowel syndrome显示文摘 | Price DD Zhou Q Moshiree B | 2006 | J Pain2006，7，8： | 1 |
| 6 | Comparison of the Effect of Azithromycin Versus Erythromycin on Antroduodenal Pressure Profiles of Patients with Chronic Functional Gastrointestinal Pain and Gastroparesis显示文摘 | Baharak Moshiree Renee McDonald Wei Hou Phillip P. Toskes | 2010 | Digestive Diseases and Sciences2010，，3： | 1 |
| 7 | Current developments for the diagnosis and treatment of irritable bowel syndrome显示文摘 | Grundmann O Yoon SL Moshiree B | 2010 | Curr Pharm Des2010，16，33： | 1 |
| 8 | Effect of azithromycin on small bowel motility in patients with gastrointestinal dysmotility显示文摘 | Payam Chini Phillip P. Toskes Shamaila Waseem Wei Hou Renee McDonald Baharak Moshiree | 2012 | Scandinavian Journal of Gastroenterology2012，，4： | 1 |
| 9 | Comparison of the effect of azithromycin versus erythromycin on antroduodenal pressure profiles of patients with chronic functional gastrointestinal pain and gastroparesis显示文摘 | Moshiree B McDonald R Hou W | 2010 | Dig Dis Sci2010，55，3： | 1 |
| 10 | An update on current pharmacotherapy options for dyspepsia 显示文摘 | Moshiree B Barboza J Talley N | 2013 | Expert Opin Pharmacother2013，14，13： | 1 |
| 11 | Gastroparesis current challenges diagnostic and management con siderations显示文摘 | Waseem S Moshiree B Draganov PV | 2009 | World J Gastroenterol2009，15，1： | 1 |
| 12 | Gastroparesis: symptoms, evaluation, and treatment显示文摘 | WASEEM S MOSHIREE B DRAGANOV P V | 2009 | World J Gastroenterol2009，15，： | 1 |
| 13 | An update on currentpharmacotherapy options for dyspepsia 显示文摘 | Moshiree B Barboza J Talley N | 2013 | Expert Opin Pharmacother2013，14，13： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员