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| 1 | Tissue differential expression of lycopene β-cyclase gene in papaya显示文摘Carotene pigments in flowers and fruits are distinct features related to fitness advantages such as attracting insects forpollination and birds for seed dispersal.In papaya,the flesh color of the fruit is considered a quality trait that correlateswith nutritional value and is linked to shelf-life of the fruit.To elucidate the carotenoid biosynthesis pathway in papaya,we took a candidate gene approach to clone the lycopene β-cyclase gene,LCY-B.A papaya LCY-B ortholog,cpLCY-B,was successfully identified from both cDNA and bacterial artificial chromosome(BAC)libraries and complete genomicsequence was obtained from the positive BAC including the promoter region.This cpLCY-B shared 80% amino acididentity with citrus LCY-B.However,full genomic sequences from both yellow- and red-fleshed papaya were identical.Quantitative real-time PCR(qPCR)revealed similar levels of expression at six different maturing stages of fruits forboth yellow-and red-fleshed genotypes.Further expression analyses of cpLCY-B showed that its expression levels wereseven- and three-fold higher in leaves and,respectively,flowers than in fruits,suggesting that cpLCY-B is down-regulatedduring the fruit ripening process. | Rachel L Skelton Qingyi Yu Rajeswari Srinivasan Richard Manshardt Paul H Moore Ray Ming | 2006 | Cell Research2006，16，8： | 8 |
| 2 | Outcomes and patients' perspectives of transition from paediatric to adult care in inflammatory bowel disease显示文摘AIM: To describe the disease and psychosocialoutcomes of an inflammatory bowel disease(IBD) transition cohort and their perspectives.METHODS: Patients with IBD, aged > 18 years, who had moved from paediatric to adult care within 10 years were identified through IBD databases at three tertiary hospitals. Participants were surveyed regarding demographic and disease specific data and their perspectives on the transition process. Survey response data were compared to contemporaneously recorded information in paediatric service case notes. Data were compared to a similar age cohort who had never received paediatric IBD care and therefore who had not undergone a transition process. RESULTS: There were 81 returned surveys from 46 transition and 35 non-transition patients. No statistically significant differences were found in disease burden, disease outcomes or adult roles and responsibilities between cohorts. Despite a high prevalence of mood disturbance(35%), there was a very low usage(5%) of psychological services in both cohorts. In the transition cohort, knowledge of their transition plan was reported by only 25/46 patients and the majority(54%) felt they were not strongly prepared. A high rate(78%) of discussion about work/study plans was recorded prior to transition, but a near complete absence of discussion regarding sex(8%), and other adult issues was recorded. Both cohorts agreed that their preferred method of future transition practices(of the options offered) was a shared clinic appointment with all key stakeholders. CONCLUSION: Transition did not appear to adversely affect disease or psychosocial outcomes. Current transition care processes could be optimised, with better psychosocial preparation and agreed transition plans. | Alice L Bennett David Moore Peter A Bampton Robert V Bryant Jane M Andrews | 2016 | World Journal of Gastroenterology2016，22，8： | 3 |
| 3 | The learning curve for laparoscopic cholecystectomy显示文摘 | The Southern Surgeons Club Michael J Moore Charles L Bennett | 1995 | The American Journal of Surgery1995，，1： | 2 |
| 4 | 植物交替氧化酶(AOX)在大肠杆菌中优化表达显示文摘植物交替氧化酶(Alternative Oxidase,AOX)位于高等植物线粒体内膜,从细胞色素途径的辅酶Q分岔,催化4个电子还原氧分子形成水的另一终端氧化酶。分离纯化有活性的AOX比较困难。本文研究AOX原核表达,选择pFLAG-1分泌表达载体,用异丙基硫代-β-D-半乳糖苷(IPTG)诱导AOX优化表达,pFLAG-1-AOX大肠杆菌优化表达条件为:宿主DH5α、温度37℃、细胞密度OD600=0.6、IPTG浓度0.2mmol/L,诱导后60min收获细胞;获得少量可溶的细胞外周质AOX和大量不溶的AOX,为深入研究AOX打下基础,同时为研究膜蛋白原核表达提供依据。 | 王雅英 Moore A L 杨盛昌 田惠桥 | 2007 | 云南植物研究2007，29，1： | 2 |
| 5 | High efficiency intracellular magnetic labeling with novel super-paramagnetic targeted peptide conjugates显示文摘 | Tung CH Moore A | 1999 | Bioconjug Chem1999，10，2： | 1 |
| 6 | 显示文摘 | GAYLOR D W MOORE J A | 2004 | Regulatory Toxicology and Pharmacology2004，39，： | 1 |
| 7 | Therapeutic use of etanercept in polyarticular course juvenile idiopathic arthritis over a two year period显示文摘 | Kietz D A Pepmueller P H Moore T L | 2002 | Ann Rheum Dis2002，61，2： | 1 |
| 8 | Hemicellulose monosaccharide composition and in vitro disappearance of orchard grass and alfalfa hay 显示文摘 | Wedig C L Jaster E H Moore K J | 1987 | Journal of Agricultural Food Chemistry1987，35，2： | 1 |
| 9 | HMG-CoA reductase guides migrating primordial germ cells显示文摘 | van Doren M Broihier H T Moore L A | 1998 | Nature1998，396，6710： | 1 |
| 10 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 11 | Comparative physiology of Synechococcus and Prochlorococcus : Influence of light and temperature on growth, pigments, fluorescence and absorptive properties显示文摘 | MOORE L R GOERICKE R CHISHOLM S W | 1995 | Marine Ecology Progress Series1995，116，： | 1 |
| 12 | The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor显示文摘 | WANG H W LI H MOORE L B | 2008 | Mol Endocrinol2008，22，4： | 1 |
| 13 | Experimental behavior of a steel structure under natural fire 显示文摘 | Wald F Sim?es da Silva L Moore D B | 2006 | Fire Safety Journal2006，41，7： | 1 |
| 14 | Protein kinase-mediated regulation of the Na^+/H^+ exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways显示文摘 | Moor AN Fliegel L | 1999 | J Biol Chem1999，274，22： | 1 |
| 15 | Gelation and clarification of concentrated orange juices I introduction and present status显示文摘 | Wenzel F W Moore E L Rouse A H | 1951 | Food Technology1951，，5： | 1 |
| 16 | The impact of behavior and addiction on psychological models of cigarette and alcohol use during pregnancy显示文摘 | Moore P J Turner R Park C L | 1996 | Addictive Behavior1996，21，5： | 1 |
| 17 | Predictive value of cell cycle markers p53,mdm2,p21 and ki-67 in superficial bladder tumor recurrence显示文摘 | Pfister C Moore L Allard P | 1999 | Clin Cancer Res1999，5，： | 1 |
| 18 | GMP -140, a platelet alph a granule membrane protein is also synthesized by vascular endothelial cells and islocalized in Weibel - Palade bodies显示文摘 | MCEVER R P BECKSTEAD J H MOORE K L | 1989 | J Clin Invest1989，84，1： | 1 |
| 19 | 显示文摘 | Moore BB Murray L Das A | 2006 | Am J Respir Cell Mol Biol2006，35，2： | 1 |
| 20 | Differential gene expression following early renal ischemia/reperfusion 显示文摘 | Supavekin S Zhang W Kucherlapati R Kaskel F J Moore L C Devarajan P | 2003 | Kid Int2003，63，： | 1 |
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