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| 1 | Drying characteristics and quality of bananas under infrared radiation heating显示文摘Hot air(HA)drying of banana has low drying efficiency and results in undesirable product quality.The objectives of this research were to investigate the feasibility of infrared(IR)heating to improve banana drying rate,evaluate quality of the dried product,and establish models for predicting drying characteristics.Banana slices of 5 mm and 8 mm thickness were dried with IR and HA at product temperatures of 60℃,70℃ and 80℃.Banana drying characteristics and changes in residual polyphenol oxidase(PPO),Hydroxymethylfurfural(HMF),color,moisture content(MC)and water activity during the treatments were investigated.Results showed that significant moisture reduction and higher drying rates were achieved with IR drying compared to HA drying in the early stage.The drying data could be fitted to the Page model for accurate prediction of MC change for IR and HA drying with mean R2 of 0.983.It was noted that enzyme inactivation occurred more quickly with IR than with HA drying.A unique response of PPO under IR and HA drying was revealed.IR heating of banana inactivated PPO within the first 20 min of drying at 60℃,70℃ and 80℃,while PPO was first activated before inactivation at 60℃ and 70℃ drying with HA.The highest HMF content occurred in banana slices with 5 mm thickness dried with IR at a product temperature of 80℃.It is therefore recommendable to dry banana with IR at product temperature of 70℃ or below to preserve the product quality.These findings are new and provide more insight in the application of IR heating for drying banana for improved drying rate and product quality. | Milly A.Pekke Zhongli Pan Griffiths G.Atungulu Gary Smith James F.Thompson | 2013 | International Journal of Agricultural and Biological Engineering2013,6,3: | 11 |
| 2 | Frailty,sarcopenia and cachexia in heart failure patients:Different clinical entities of the same painting显示文摘Heart Failure(HF)in elderly patients is a systemic syndrome where advanced age,comorbidities with organ system deterioration,frailty and impaired cognition significantly impact outcome.Cardiac cachexia,sarcopenia and frailty despite overlap in definitions are different clinical entities that frequently coexist in HF patients.However,these co-factors often remain unaddressed,resulting in poor quality-of-life,prolonged physical disability and exercise intolerance and finally with higher rehospitalization rates and mortality.Strategy aim to increase muscle mass and muscle strength and delay the occurrence of frailty state appear essential in this regard.Common HF drugs therapy(b-blockers,angiotensinconverting enzyme inhibitors)and prescription of physical exercise program remain the cornerstone of therapeutic approach in HF patients with new promising data regarding nutritional supplementation.However,the treatment of all these conditions still remain debated and only a profound knowledge of the specific mechanisms and patterns of disease progression will allow to use the appropriate therapy in a given clinical setting.For all these reasons we briefly review current knowledge on frailty,sarcopenia and cachexia in HF patients with the attempt to define clinically significant degrees of multiorgan dysfunction,specific'red alert'thresholds in clinical practice and therapeutic approach. | Matteo Beltrami Carlo Fumagalli Massimo Milli | 2021 | World Journal of Cardiology2021,13,1: | 7 |
| 3 | Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review显示文摘Adenosquamous carcinoma of the pancreas(ASCP)is a rare entity. Like adenocarcinoma of the pancreas,overall survival is poor. Characteristics of ASCP include central tumor necrosis, along with osteoclasts and hypercalcemia. Various theories exist as to why this histological subtype exists, as normal pancreas tissue has no benign squamous epithelium. Due to the rarity of this disease, limited molecular analysis has been performed, and those reports indicate unique molecular features of ASCP. In this paper, we characterize 23 patients diagnosed with ASCP through molecular profiling using immunohistochemistry staining, fluorescent in situ hybridization, chromogenic in situ hybridization, and gene sequencing, Additionally, we provide a comprehensive literature review of what is known to date of ASCP.Molecular characterization revealed overexpression in MRP1(80%), MGMT(79%), TOP2A(75), RRM1(42%),TOPO1(42%), PTEN(45%), CMET(40%), and C-KIT(10%) among others. One hundred percent of samples tested were positive for KRAS mutations. This analysis shows heretofore unsuspected leads to be considered for treatments of this rare type of exocrine pancreas cancer. Molecular profiling may be appropriate to provide maximum information regarding the patient's tumor. Further work should be pursued to better characterize this disease. | Erkut Borazanci Sherri Z Millis Ron Korn Haiyong Han Clifford J Whatcott Zoran Gatalica Michael T Barrett Derek Cridebring Daniel D Von Hoff | 2015 | World Journal of Gastrointestinal Oncology2015,7,9: | 6 |
| 4 | China organ donation and transplantation update: the Hangzhou Resolution显示文摘The much-anticipated change in the practice of organ donation and transplantation in China is now underway and affirmed by an important Hangzhou Resolution promulgated at the 2013 China Transplant Congress.Support of the National Health and Family Planning Commission On October 29,2013,in a meeting of the National Health and Family Planning Commission (NHFPC)officials with Jie-Fu Huang,Head of National Organ Transplant Committee(OTC), Hai-Bo Wang,Director of China Organ Transplant Response System (COTRS) | Jie-Fu Huang Shu-Sen Zheng Yong-Feng Liu Hai-Bo Wang Jeremy Chapman Philip O'Connell Michael Millis John Fung Francis Delmonico | 2014 | Hepatobiliary & Pancreatic Diseases International2014,13,2: | 6 |
| 5 | Risk of Melanoma and Nonmelanoma Skin Cancer Among Patients With Inflammatory Bowel Disease显示文摘 | Millie D. Long Christopher F. Martin Clare A. Pipkin Hans H. Herfarth Robert S. Sandler Michael D. Kappelman | 2012 | Gastroenterology2012,,2: | 4 |
| 6 | Increased Risk for Non-Melanoma Skin Cancer in Patients With Inflammatory Bowel Disease显示文摘 | Millie D. Long Hans H. Herfarth Clare A. Pipkin Carol Q. Porter Robert S. Sandler Michael D. Kappelman | 2010 | Clinical Gastroenterology and Hepatology2010,,3: | 3 |
| 7 | Sleep Disturbance and Risk of Active Disease in Patients With Crohn’s Disease and Ulcerative Colitis显示文摘 | Ashwin N. Ananthakrishnan Millie D. Long Christopher F. Martin Robert S. Sandler Michael D. Kappelman | 2013 | Clinical Gastroenterology and Hepatology2013,,: | 3 |
| 8 | Use of the tumor necrosis factor-blockers for Crohn's disease显示文摘The use of anti-tumor necrosis factor-therapy for inflammatory bowel disease represents the most important advance in the care of these patients since the publication of the National Co-operative Crohn's disease study thirty years ago.The recommendations of numerous consensus groups worldwide are now supported by a wealth of clinical trials and several meta-analyses.In general,it is suggested that tumor necrosis factor-blockers(TNFBs) are indicated(1) for persons with moderately-severe Crohn's disease or ulcerative colitis(UC) who have failed two or more causes of glucocorticosteroids and an acceptably long cause(8 wk to 12 wk) of an immune modulator such as azathioprine or methotrexate;(2) non-responsive perianal disease;and(3) severe UC not responding to a 3-d to 5-d course of steroids.Once TNFBs have been introduced and the patient is responsive,therapy given by the IV and SC rate must be continued.It remains open to definitive evidence if concomitant immune modulators are required with TNFB maintenance therapy,and when or if TNFB may be weaned and discontinued.The supportive evidence from a single study on the role of early versus later introduction of TNFB in the course of a patient's illness needs to be confirmed.The risk/benefit profile of TNFB appears to be acceptable as long as the patient is immunized and tested for tuberculosis and viral hepatitis before the initiation of TNFB,and as long as the long-term adverse effects on the development of lymphoma and other tumors do not prone to be problematic.Because the rates of benefits to TNFB are modest from a population perspective and the cost of therapy is very high,the ultimate application of use of TNFBs will likely be established by cost/benefit studies. | Alan BR Thomson Milli Gupta Hugh J Freeman | 2012 | World Journal of Gastroenterology2012,18,35: | 3 |
| 9 | MTT细胞毒性试验参数验证显示文摘MTT细胞毒性试验为常见的细胞毒性试验,其广泛地应用于国内外医疗器械生物相容性检测并为ISO10993所推荐。文章就该试验的几项参数细胞代数、加样时间、血清类型和阴性对照毒性范围等对该试验的影响进行了验证,以说明在该中心试验条件下该试验的稳定性,同时为标准实验操作提供参考。 | 徐彪 王友红 杜莎莎 左楠 Millie Chen | 2020 | 中国医疗器械信息2020,26,7: | 3 |
| 10 | Fermi-liquid-to-polaron crossover Ⅱ double exchange and the physics of colossal magnetoresistance 显示文摘 | Millis A J Mueller R Shraiman B I | 1996 | Phys Rev B1996,54,: | 2 |
| 11 | Evaluation of a Non-invasive Method to Detect Cytomegalovirus (CMV)-DNA in Stool Samples of Patients with Inflammatory Bowel Disease (IBD): A Pilot Study显示文摘 | Hans H. Herfarth Millie D. Long Tara C. Rubinas Mikki Sandridge Melissa B. Miller | 2010 | Digestive Diseases and Sciences2010,,4: | 2 |
| 12 | Effects of Magnetic Ordering on the Anisotropy and Temperature Dependence of the Optical Conductivity in LaMnO3: A Tight-Binding Approach 显示文摘 | Ahn K H Millis A J | 2000 | Phys Rev2000,61,12: | 2 |
| 13 | Double exchange alone does not explain the resistivity of La1-xSrxMnO3 phys 显示文摘 | Millis A J Littlewood P B Shraiman B I | 1995 | Rev Lett1995,74,: | 2 |
| 14 | Eatimation of the Brooks-Corey parameters from water retonfion data显示文摘 | MILLY P C D | 1987 | Water Resource Research1987,23,: | 1 |
| 15 | The role of tumor necrosis factor in alograft rejection 显示文摘 | MILLIS JM OLTHOFF KM | 1990 | Transplantation1990,50,: | 1 |
| 16 | Using absorbance and fluorescence spectra to discriminate microalage 显示文摘 | Millie D F Schofield O M Kirkpatryck G J | 2002 | European Journal of Phycology2002,37,3: | 1 |
| 17 | Heterogeneity of cadmiumconcentration in soils as a source of uncertainty in plant uptake andits implications for human health risk assessment显示文摘 | Millis P R Ramsey M H Jone E A | 2004 | Science ofTotal Environment2004,326,13: | 1 |
| 18 | Cyclin D1 and asso- ciated proteins inmammary ductal carcinoma in situ and a- typical ductal hyperplasia 显示文摘 | Gillett CE Lee AHS Millis RR | 1998 | J Pathol1998,184,4: | 1 |
| 19 | 显示文摘 | Millis A J Boris I Shraiman Mueller R | 1996 | Phys Rev Lett1996,77,: | 1 |
| 20 | Detection of harmful algal blooms using photopigments and absorption signatures: A case study of the florida red tide dinoflagellate, Gymnodinium Breve 显示文摘 | Millie D F Schofield O M Kirkpatryck G J | 1997 | Limnology and Oceanography1997,42,5: | 1 |