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| 1 | Comparative review of vertebroplasty and kyphoplasty显示文摘The aim of this review is to compare the effectiveness of percutaneous vertebroplasty and kyphoplasty to treat pain and improve functional outcome from ver-tebral fractures secondary to osteoporosis and tumor conditions. In 2009, two open randomized controlled trials published in the New England Journal of Medicine questioned the value of vertebroplasty in treating ver-tebral compression fractures. Nevertheless, the prac-tice of physicians treating these conditions has barely changed. The objective of this review is to try to clarify the most important issues, based on our own experi-ence and the reported evidence about both techniques, and to guide towards the most appropriate choice of treatment of vertebral fractures, although many ques-tions still remain unanswered. | Ferno Ruiz Santiago Alicia Santiago Chinchilla Luis Guzmán álvarez Antonio Luis Pérez Abela Maria del Mar Castellano García Miguel Pajares López | 2014 | World Journal of Radiology2014，6，6： | 30 |
| 2 | 2型糖尿病患者个体化血糖控制目标和药物治疗显示文摘'有效管理糖尿病全球合作组织'(下称'糖尿病全球合作组织')成立的宗旨是为临床提供实用指南以改善糖尿病患者的预后,制定并修改相关策略以改善T2DM患者血糖控制情况。糖尿病全球合作组织提倡对糖尿病患者实行个体化治疗方案,明确需要特殊考虑T2DM患者亚组人群。这篇文章基于此前发表的文献,扩大了实用指南的范围,包括有并发症的新诊断T2DM患者和妊娠期糖尿病(GDM)患者。良好血糖控制是T2DM管理的基石,在预防或延缓糖尿病并发症的发生、发展过程中发挥重要作用。个体化治疗目标和安全及时的血糖达标治疗方案至关重要。另外,还需制定更全面的护理计划以降低心血管风险和改善患者预后。 | 张晓梅 纪立农 Bailey CJ Aschner P Stefano Del Prato LaSalle J JI Li-nong Matthaei S | 2014 | 中国糖尿病杂志2014，22，10： | 16 |
| 3 | 应用组织型纤溶酶原激活物行静脉溶栓治疗急性缺血性卒中的时间窗延长——美国心脏协会/美国卒中协会的科学建议显示文摘美国心脏协会卒中委员会发布了关于急性缺血性卒中的现行治疗指南,其中包括应用重组组织型纤溶酶原激活物(rt—PA)行静脉溶栓的建议。尽管该药对改善神经功能预后有一定的疗效,但由于患者通常在发病3h后方能到达医院,往往已经超过了用药的时间窗。因此,大部分缺血性卒中患者未能接受rt—PA治疗。目前研究认为,增加rt—PA治疗例数的最可能方法就是延长治疗时间窗。 | del Zoppo G J Saver J L Jauch E C Adams H P Jr. | 2009 | 中国脑血管病杂志2009，6，8： | 8 |
| 4 | Effect of Nd3+doping on structure,microstructure,lattice distortion and electronic properties of TiO_2 nanoparticles显示文摘Doped and undoped TiCh nanoparticles were prepared by Stober method and thermally treated at 600 ℃.The effect of Nd^(3+) ion on the structure and micro structure of anatase-phase TiCh nanocrystals was studied by Rietveld refinement method using X-ray powder diffraction data.Bond lengths,bond angles,and edges distances were analyzed.The phase formation was confirmed by high-resolution transmission electron microscopy.The adjustment of Ti-0 bond length induced by the addition of Nd^(3+) ions,reduced the octahedral distortion and altered the octahedral array in the anatase-phase TiCh nanocrystal.The changes of structure and microstructure were mainly observed for TiCh nanoparticles doped with 0.1 at.%of Nd^(3+) ions and attributed to the cationic substitution of Ti^(4+) ions which promoted changes in the density of states and gap band of TiCh.The dopant insertion resulted in a better structural stability of the nanocrystals that enhanced their charge transference and photocatalytic efficiency. | Balter Trujillo-Navarrete María del Pilar Haro-Vázquez Rosa María Félix-Navarro Francisco Paraguay-Delgado Henry Alvarez-Huerta Sergio Pérez-Sicairos Edgar Alonso Reynoso-Soto | 2017 | Journal of Rare Earths2017，35，3： | 2 |
| 5 | 精氨酸酶-内皮型一氧化氮合酶失衡促进慢性间歇性缺氧期间的内皮功能障碍显示文摘慢性间歇性缺氧(chronic intermittent hypoxia,CIH)是阻塞性睡眠呼吸暂停的主要特征,与血管功能损害相关,尽管其不会改变血管对一氧化氮供体的反应。该研究旨在探讨精氨酸酶是否促进CIH大鼠血管内皮功能障碍。 | 刘莉 叶鹏 Krause BJ Del Rio R Moya EA Marquez-Gutierrez M Casanello P Iturriaga R | 2015 | 中华高血压杂志2015，23，5： | 2 |
| 6 | Nitric-oxide releasing molecules: a new class of drugs with several major indications 显示文摘 | Burgaud JL Riffaud JP Del Soldato P | 2002 | Curr Pharm Design2002，8，3： | 2 |
| 7 | Liver Retransplantation in HIV‐Infected Patients: A Prospective Cohort Study显示文摘 | M. Gastaca F. Aguero A. Rimola M. Montejo P. Miralles R. Lozano L. Castells M. Abradelo M. de la Mata F. San Juan Rodríguez E. Cordero S. del Campo C. Manzardo J.O. de Urbina I. Pérez G. de la Rosa J. M. Miro | 2012 | American Journal of Transplantation2012，，9： | 2 |
| 8 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 9 | Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients显示文摘 | Manuel Romero-Gómez Maria Del Mar Viloria Raúl J. Andrade Javier Salmerón Moisés Diago Conrado M. Fernández-Rodríguez Raquel Corpas Marina Cruz Lourdes Grande Luis Vázquez Paloma Mu?oz-de-Rueda Pilar López-Serrano Ana Gila María L. Gutiérrez Celia Pérez A | 2005 | Gastroenterology2005，，3： | 2 |
| 10 | Clinical significance of'anti-HBc alone'in human immunodeficiency virus-positive patients显示文摘AIM:To determine the prevalence and clinical relevance of isolated antibodies to hepatitis B core antigen as the only marker of infection('anti-HBc alone')among human immunodeficiency virus(HIV) type-1 infected patients.Occult hepatitis B infection frequency was also evaluated. METHODS:Three hundred and forty eight histories from 2388 HIV-positive patients were randomly reviewed.Patients with serological markers of hepatitis B virus(HBV)infection were classified into three groups:past hepatitis,'anti-HBc alone'and chronic hepatitis.Determination of DNA from HBV,and RNA and genotype from hepatitis C virus(HCV)were performed on'anti-HBc alone'patients. RESULTS:One hundred and eighty seven(53.7%) HIV-positive patients had markers of HBV infection: 118 past infection(63.1%),14 chronic hepatitis (7.5%)and 55'anti-HBc alone'(29.4%).Younger age[2.3-fold higher per every 10 years younger;95% confidence intervals(CI)1.33-4.00]and antibodies to HCV infection[odds ratio(OR)2.87;95%CI 1.10-7.48]were factors independently associated with the'anti-HBc alone'pattern.No differences in liver disease frequency were detected between both groups. Serum levels of anti-HBs were not associated with HCV infection(nor viral replication or HCV genotype),or with HIV replication or CD4 level.No'anti-HBc alone' patient tested positive for HBV DNA. CONCLUSION:'Anti-HBc alone'prevalence in HIVpositive patients was similar to previously reported data and was associated with a younger age and with antibodies to HCV infection.In clinical practice,HBV DNA determination should be performed only in those patients with clinical or analytical signs of liver injury. | M~aTeresa Pérez-Rodríguez Bernardo Sopea Manuel Crespo Alberto Rivera Teresa González del Blanco Antonio Ocampo César Martínez-Vázquez | 2009 | World Journal of Gastroenterology2009，15，10： | 2 |
| 11 | Effect of sheet thickness on the microstructural evolution of an Mg AZ61 alloy during large strain hot rolling显示文摘 | M.T Pérez-Prado J.A del Valle O.A Ruano | 2003 | Scripta Materialia2003，，5： | 2 |
| 12 | Achieving high strength in commercial Mg cast alloys through large strain rolling显示文摘 | M.T. Pérez-Prado J.A. del Valle O.A. Ruano | 2005 | Materials Letters2005，，26： | 2 |
| 13 | Dendritic cell-mediated cross presentation of antigens derived from colon carcinoma cells exposed to a highly eytotoxie multidrug regimen with gemcitabine, oxaliplatin, 5 fluorouracil,and leucovorin, elicits a powerful human antigenspecific CTL response with antitumor activity in vitro显示文摘 | Correale P Cusi M G Del Vecchio M T Aquino A Prete S P Tsang K Y | 2005 | J Immunol2005，175，： | 1 |
| 14 | Coloring of titanium through laser oxidation: Comparative study with anodizing 显示文摘 | Perez Del P Ferndndez-Pradas J M Serra P | 2004 | Surface and Coatings Technology2004，187，1： | 1 |
| 15 | Characterization of a common precursor population for dendritic cells显示文摘 | del Hoyo GM Martin P Vargas HH | 2002 | Nature2002，415，6875： | 1 |
| 16 | A chemical, morphological, and electrochemical (XPS, SEM/EDX, CV, and EIS) analysis of electrochemically modified electrode surfaces of natural chalcopyrite (CuFeS2) and pyrite (FeS2) in alkaline solutions显示文摘 | VELASQUEZ P LEINEN D PASCUAL J RAMOS- BARRADO J R GREZ P GOMEZ H SCHREBLER R DEL RiO R CORDOVA R | 2005 | Journal of Physical Chemistry B2005，109，1： | 1 |
| 17 | Guidelines for the early management of patients with ischemic stroke : 2005 guidelines update : a scientific statement from the Stroke Council of the American Harct Assoeiation/American Stroke Assoeiation显示文摘 | Adams H P Adams R Del Zoppo G | 2005 | Stroke2005，36，1： | 1 |
| 18 | Is it the agent or the blood pressure level that matters for renal and vascular protection in ehronie nephropathies? 显示文摘 | LOCATELLI F DEL VECCHIO L POZZONI P | 2005 | Kidney Int Suppl2005，，93： | 1 |
| 19 | Focal adhesion kinase as a RhoA-activablc signaling scaffold mediating Akt activation and cardiomyocyte protection显示文摘 | Del Re D P Miyamoto S Brown J H | 2008 | J Biol Chem2008，283，35： | 1 |
| 20 | The food contami- nant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression 显示文摘 | Pinton P Nougayrede J P Del rio J C | 2009 | Toxicol Appl Pharmacol2009，237，： | 1 |
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