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| 1 | Progress and recent trend in MILD combustion显示文摘Moderate or intense low oxygen dilution(MILD)combustion plays a significant role in the mitigation of combustion-generated pollutants and greenhouse gases whilst meeting thermal efficiency needs.However,due to the lack of the fundamental knowledge on this combustion,there is a misconception that MILD combustion should be established by high preheating of the air,which has limited its application.Our research and development on this combustion has been performed for several years. We have found that the requirements for establishing the MILD combustion are more relaxed than previously.It is also revealed that this combustion of different type,i.e.,non-premixed,partially premixed and fully premixed,can be achieved by firing various fuels(i.e.,gaseous,liquid and solid fuels).It is suggested that the application of the MILD combustion can be expanded significantly.The present review summarizes the progress and recent trend made in the R&D of this combustion and recommends further fundamental studies for improving our knowledge and widening its applications. | LI PengFei MI JianChun DALLY B B WANG FeiFei WANG Lin LIU ZhaoHui CHEN Sheng ZHENG ChuGuang | 2011 | Science China(Technological Sciences)2011，54，2： | 31 |
| 2 | Digestive tract reconstruction using isoperistaltic jejunumlater-cut overlap method after totally laparoscopic total gastrectomy for gastric cancer: Short-term outcomes and impact on quality of life显示文摘AIM To evaluate the short-term outcomes and quality of life(Qo L) in gastric cancer patients undergoing digestive tract construction using the isoperistaltic jejunum-latercut overlap method(IJOM) after totally laparoscopic total gastrectomy(TLTG).METHODS A total of 507 patients who underwent laparoscopic gastrectomy(D2) from January 2014 to March 2016 were originally included in the study. The patients were divided into two groups to undergo digestive tract construction using either IJOM after TLTG(group T, n = 51) or Roux-en-Y anastomosis after laparoscopic-assisted total gastrectomy(LATG)(group A, n = 456). The short-term outcomes and Qo L were compared between the two groups after 1:2 propensity-score matching(PSM). We used a questionnaire to assess Qo L.RESULTS Before matching, age, sex, tumor size, tumor location, preoperative albumin and blood loss were significantly different between the two groups(P < 0.05). After PSM, the patients were well balanced in terms of their clinicopathological characteristics, although both blood loss and in-hospital postoperative days in group T were significantly lower than those in group A(P < 0.05). After matching, group T reported better Qo L in the domains of pain and dysphagia. Among the items evaluating pain and dysphagia, group T tended to report better Qo L('Have you felt pain' and 'Have you had difficulty eating solid food')(P < 0.05).CONCLUSION The IJOM for digestive tract reconstruction after TLTG is associated with reduced blood loss and less pain and dysphagia, thus improving Qo L after laparoscopic gastrectomy. | Ze-Ning Huang Chang-Ming Huang Chao-Hui Zheng Ping Li Jian-Wei Xie Jia-Bin Wang Jian-Xian Lin Jun Lu Qi-Yue Chen Long-Long Cao Mi Lin Ru-Hong Tu Ju-Li Lin | 2017 | World Journal of Gastroenterology2017，23，39： | 27 |
| 3 | Comparision of modified and conventional delta-shaped gastroduodenostomy in totally laparoscopic surgery显示文摘AIM:To evaluate the safety and feasibility of a modified delta-shaped gastroduodenostomy(DSG)in totally laparoscopic distal gastrectomy(TLDG).METHODS:We performed a case-control study enrolling 63 patients with distal gastric cancer(GC)undergoing TLDG with a DSG from January 2013 to June 2013.Twenty-two patients underwent a conventional DSG(Con-Group),whereas the other 41 patients underwent a modified version of the DSG(Mod-Group).The modified procedure required only the instruments of the surgeon and assistant to complete the involution of the common stab incision and to completely resect the duodenal cutting edge,resulting in an anastomosis with an inverted T-shaped appearance.The clinicopathological characteristics,surgical outcomes,anastomosis time and complications of the two groups were retrospectively analyzed using a prospectively maintained comprehensive database.RESULTS:DSG procedures were successfully completed in all of the patients with histologically complete(R0)resections,and none of these patients required conversion to open surgery.The clinicopathological characteristics of the two groups were similar.There were no significant differences between the groups in the operative time,intraoperative blood loss,extension of the lymph node(LN)dissection and number of dissected LNs(150.8±21.6 min vs 143.4±23.4 min,P=0.225for the operative time;26.8±11.3 min vs 30.6±14.8mL,P=0.157 for the intraoperative blood loss;4/18 vs3/38,P=0.375 for the extension of the LN dissection;and 43.9±13.4 vs 39.5±11.5 per case,P=0.151 for the number of dissected LNs).The anastomosis time,however,was significantly shorter in the Mod-Group than in the Con-Group(13.9±2.8 min vs 23.9±5.6min,P=0.000).The postoperative outcomes,including the times to out-of-bed activities,first flatus,resumption of soft diet and postoperative hospital stay,as well as the anastomosis size,did not differ significantly(1.9±0.6 d vs 2.3±1.5 d,P=0.228 for the time to outof-bed activities;3.2±0.9 d vs 3.5±1.3 d,P=0.295for the first flatus time;7.5±0.8 d vs 8.1±4.3 d,P=0.489 for the resumption of a soft diet time;14.3±10.6 d vs 11.5±4.9 d,P=0.148 for the postoperative hospital stay;and 30.5±3.6 mm vs 30.1±4.0 mm,P=0.730 for the anastomosis size).One patient with minor anastomotic leakage in the Con-Group was managed conservatively;no other patients experienced any complications around the anastomosis.The operative complication rates were similar in the Con-and ModGroups(9.1%vs 7.3%,P=1.000).CONCLUSION:The modified DSG,an alternative reconstruction in TLDG for GC,is technically safe and feasible,with a simpler process that reduces the anastomosis time. | Chang-Ming Huang Mi Lin Jian-Xian Lin Chao-Hui Zheng Ping Li Jian-Wei Xie Jia-Bin Wang Jun Lu | 2014 | World Journal of Gastroenterology2014，20，30： | 26 |
| 4 | An analysis of patients receiving emergency CAG without PCI and the value of GRACE score in predicting PCI possibilities in NSTE-ACS patients显示文摘BackgroundThere 是经历了紧急情况的病人冠的 angiography (CAG ) 但是没收到经皮的冠的干预(一种总线标准) 。学习是分析这些 reasons.MethodsThis 的这的目的是单个中心的回顾的研究。我们招募了 201 consecutive 收到了紧急情况 CAG 的病人但是没收到一种总线标准。为了在在非圣预言一种总线标准可能性调查尖锐冠的事件(优雅)分数的全球注册表的值,分割举起急性冠的症候群(NSTE交流)病人,我们招募了 80 ;与NSTE交流介绍了并且收到了紧急情况 CAG 以及紧急情况 PCI.ResultsAmong 的连续病人收到了紧急情况 CAG 的 201 个病人但是没收到一种总线标准,26%病人有除冠的心疾病以外的最后的诊断。在有重要冠的动脉狭窄的病人, 23 个病人(11.5%) 被推荐到冠的动脉绕过 grafting (CABG ) ,一个病人(0.5%) 拒绝了一种总线标准;有重要血栓负担的 13 个病人(6.5%) 与 glycoprotein IIb/IIIa 受体对手被对待;74 个病人(36.8%) 与药治疗被对待因为没有严重狭窄(>70%) 在罪容器是在场的。而且, 201 个病人中的 80 个与 NSTE 交流被介绍(与除冠的心疾病以外的最后的诊断排除那些病人,排除那些病人为 CABG 治疗计划了) ,是参考了非一种总线标准 NSTE 交流。当比较时,他们的优雅得分,象紧急情况一种总线标准一样收到了紧急情况 CAG 的 80 个连续病人与 NSTE 交流介绍了(作为一种总线标准 NSTE 交流参考了) ,我们发现一种总线标准 NSTE 交流病人有显著地更高的优雅分数与相比非一种总线标准 NSTE 交流病人。我们然后使用了接收装置操作员典型曲线(巨鸟) 测试 GRACE 分数是否擅长在 NSTE 交流病人评估一种总线标准的可能性。在 curve 下面的区域;是 0.854 ±0.030 (P <0.001 ) ,显示好预兆的价值。而且,我们分析了从巨鸟统计导出的结果,并且发现那 125.5 的一个优雅分数,作为一截止,在在 NSTE 交流 patients.ConclusionsOur 调查结果评估一种总线标准可能性让高敏感和特性显示 GRACE 分数在决定 NSTE 交流病人是否将收到一种总线标准有预兆的价值。 | Bo-Da ZHOU | 2015 | Journal of Geriatric Cardiology2015，12，3： | 15 |
| 5 | Altered serum level of cartilage oligomeric matrix protein and its association with coronary calcification in patients with coronary heart disease显示文摘BackgroundCartilage oligomeric 矩阵蛋白质(COMP ) 主要在骨胳的系统和脉管的光滑的肌肉房间被发现。最近的研究证明它在血容器上有保护的功能并且能也禁止脉管的石灰化。我们在冠的心疾病( CHD )调查了浆液 COMP 病人,并且在浆液 COMP 和首先经历了多片跟随的冠的 angiography 的 233 个连续的胸疼痛病人全部的冠的 artery.MethodsA 的石灰化之间的关系在六个月以内计算了断层摄影术( MSCT )被招募并且根据缩小百分比的冠的 angiography 钠直径划分了成二个组:CHD 组(缩小 50% 的直径, n = 194 ) 并且控制组(直径变窄 <50% , n = 39 ) 。Gensini 分数,句法分数和冠的动脉钙分数(CAC ) 是计算的。浆液 COMP 水平用 COMP 的 ELISA.ResultsThe 层次被决定比在控制组在 CHD 组是显著地更高的 155.7 (124.5-194.5 ) ng/mL 对 128.4 (113.0-159.9 ) ng/mL, P = 0.019。在 COMP, Gensini 分数,句法分数,冠的狭窄的严厉和有狭窄的冠的动脉的数字之间没有关联 >50% 。浆液 COMP 与年龄被相关(r = 0.294, P < 0.001 ) , fasting 葡萄糖(r = 0.163, P = 0.015 ) , HbA1c (r = 0.194, P = 0.015 ) 并且 CAC (r = 0.137, P = 0.037 ) 。逐步的线性回归分析显示出那 COMP 水平,年龄是在 CHD 病人的 CAC 的独立预言者(= 0.402, t = 2.612, P = 0.015;= 0.472, t = 3.077, P = 0.005 ) 。为预言 CHD 的 COMP 的性能在曲线(AUC ) 下面作为区域被显示出:0.632, 95% CI:0.549-0.715 和上面的 tertile CAC 是 AUC:0.602, 95% CI:在操作冠的动脉的特征(巨鸟) 曲线 analysis.ConclusionCalcification 的接收装置的 0.526-0.678 是浆液 COMP 的一个独立预言者。 | Fang-Fang WANG Lahati HA Hai-Yi YU Lin MI Jiang-Li HAN Wei GAO | 2017 | Journal of Geriatric Cardiology2017，14，2： | 15 |
| 6 | Correlation between growth differentiation factor-15 and collagen metabolism indicators in patients with myocardial infarction and heart failure显示文摘BackgroundGrowth 区别因素(GDF )-15, 转变生长因素贝它总科的一个分叉的成员确实看起来响应试验性的压力超载和心失败(HF ) 的前进起来调整。HF 经常在心肌的梗塞(MI ) 以后发展,贡献更坏的结果。学习是在 HF.MethodsThe 学习的不同阶段估计在与骨胶原周转有关的 GDF-15 层次和标记之间的关联的这的目的由 179 个病人的一个队组成,包括稳定的心绞痛病人( AP 组, n = 50 ),没有 HF 的旧 MI 病人( OMI 组, n = 56 ),有 HF 的旧 MI 病人( OMI-HF 组, n = 38 )并且正常控制组( n = 35 )。包括 precollagen 反映骨胶原的合成和降级率的两指示物我N终端肽( PINP ),类型我骨胶原carboxy终端肽( ICTP ), precollagen III N终端肽( PIIINP )和 GDF-15 用连接酶的 inmunosorbent assay.ResultsThe 血浆 GDF-15 水平被测量在 OMI-HF 组是更高的( 1373.4 ± ;275.4 ng/L ) 比 OMI 组(1036.1 ±248.6 ng/L ) , AP 组(784.6 ±222.4 ng/L ) 并且控制组(483.8 ±186.4 ng/L )(P <0.001 ) 。骨胶原周转的指示物(ICTP, PINP, PIIINP ) 与控制相比在 OMI-HF 组增加的所有组织(3.03 ±1.02 µ g/L 对 2.08 ±0.95 µ g/L, 22.2 ±6.6 µ g/L 对 16.7 ±5.1 µ g/L 和 13.2 ±7.9 µ g/L 对 6.4 ±2.1 µ g/L 分别地;P <0.01 ) 。GDF-15 断然与 ICTP 和 PIIINP 相关(r = 0.302, P <0.001 并且 r = 0.206, P = 0.006,分别地) 。GDF-15 断然相关到心脏舒张的指示物 E/Em 和左 atrial 迫使的 echocardiographic (r = 0.349 并且 r = 0.358 分别地;P <0.01 ) ,并且相反地相关到收缩指示物左室的喷射部分和山峰的一般水准收缩心肌的速度(Sm )(r =− 0.623 并且 r =− 0.365 分别地;P <0.01 ).ConclusionPlasma GDF-15 与类型的指示物被联系我和 III 骨胶原周转。 | Fang-Fang WANG Bao-Xia CHEN Hai-Yi YU Lin MI Zi-Jian LI Wei GAO | 2016 | Journal of Geriatric Cardiology2016，13，1： | 14 |
| 7 | The Intervention Effect of Rosiglitozone in Ovarian Fibrosis of PCOS Rats显示文摘Objective To explore the Intervention effect of Rosiglitozone in ovarian fibrosis of PCOS rats.Methods 60 female SD rats were randomly divided into 3 groups:control group,model group and treatment group.The model and treatment groups were established by subcutaneous injection of DHEA,while the treatment group was given RGZ.The serum hormone values,pathohistology of ovarian structure of rats,ovarian ultrastructure and the expressions of TGF-β 1 and CTGF were detected.Results The PCOS model was established successfully.The expression intensity of TGF-β 1 and CTGF in Oocytes of the PCOS groups was 9.545±2.954 and 9.665±2.400,respectively and was significantly higher than that of the control group 6.636±2.264 and 7.036±2.133;after treatment with rosiglitazone,the expression was significantly decreased 6.980±2.421 and 6.642±2.721 as compared with that of the model group (P<0.05,P<0.001).The values in serum of the PCOS groups were 3.749±2.054 and 0.265±0.129,and 1.914±1.801 and 0.096±0.088 in the control group which had statistically significant difference (P<0.05,P<0.001).After treatment with rosiglitazone,the values were 2.3100±1.825 and 0.112±0.187 and were significantly different with those of the model group (P<0.05,P<0.001).Conclusion TGF-β 1 and CTGF play an important role in the development of ovary fibrosis in PCOS.However,RGZ may postpone the development of fibrosis by decreasing the levels of TGF-β 1 and CTGF. | MIAO Zhu Lin GUO Liang WANG Yong Xia CUI Rong YANG Ning HUANG Mi Qiong QIN Wei Bing CHEN Jin LI Hong Mei WANG Zi Neng WEI Xiang Cai | 2012 | Biomedical and Environmental Sciences2012，25，1： | 14 |
| 8 | Anatomy and influence of the splenic artery in laparoscopic spleen-preserving splenic lymphadenectomy显示文摘AIM: To investigate the splenic hilar vascular anatomy and the influence of splenic artery(Sp A) type in laparoscopic total gastrectomy with spleen-preserving splenic lymphadenectomy(LTGSPL).METHODS:The clinical anatomy data of 317 patients with upper- or middle-third gastric cancer who underwent LTGSPL in our hospital from January 2011 to December 2013 were collected. The patients were divided into two groups(concentrated group vs distributed group) according to the distance between the splenic artery's furcation and the splenic hilar region. Then, the anatomical layout, clinicopathologic characteristics, intraoperative variables, and postoperative variables were compared between the two groups.RESULTS: There were 205 patients with a concentrated type(64.7%) and 112 patients with a distributed type(35.3%) Sp A. There were 22 patients(6.9%) with a single branch of the splenic lobar vessels, 250(78.9%) with 2 branches, 43(13.6%) with 3 branches, and 2 patients(0.6%) with multiple branches. Eighty sevenpatients(27.4%) had type?Ⅰ?splenic artery trunk, 211(66.6%) had type Ⅱ, 13(4.1%) had type Ⅲ, and 6(1.9%) had type Ⅳ. The mean splenic hilar lymphadenectomy time(23.15 ± 8.02 vs 26.21 ± 8.84 min; P = 0.002), mean blood loss resulting from splenic hilar lymphadenectomy(14.78 ± 11.09 vs 17.37 ± 10.62 m L; P = 0.044), and number of vascular clamps used at the splenic hilum(9.64 ± 2.88 vs 10.40 ± 3.57; P = 0.040) were significantly lower in the concentrated group than in the distributed group. However, the mean total surgical time, mean total blood loss, and the mean number of harvested splenic hilar lymph nodes were similar in both groups(P > 0.05 for each comparison). There were also no significant differences in clinicopathological and postoperative characteristics between the groups(P > 0.05).CONCLUSION: It is of value for surgeons to know the splenic hilar vascular anatomy when performing LTGSPL. Patients with concentrated type Sp A may be optimal patients for training new surgeons. | Chao-Hui Zheng Mu Xu Chang-Ming Huang Ping Li Jian-Wei Xie Jia-Bin Wang Jian-Xian Lin Jun Lu Qi-Yue Chen Long-Long Cao Mi Lin | 2015 | World Journal of Gastroenterology2015，21，27： | 14 |
| 9 | Distribution and source of microplastics in China's second largest reservoir-Danjiangkou Reservoir显示文摘Fresh water microplastic pollution is of pressing concern globally,but its distribution and sources in reservoirs are poorly documented.Danjiangkou Reservoir is the second largest reservoir in China and is divided into the Han Reservoir and Dan Reservoir.In this work,microplastic abundances and morphological characteristics of the reservoir were investigated.The microplastic abundance of 15 main tributaries of the reservoir was also measured.The vertical distribution(in water column and sediment),horizontal distribution(in Han Reservoir and Dan Reservoir)and source of microplastics were analyzed.Microplastics accumulated in the middle layer of the reservoir,and the size and color of the microplastic particles changed from the surface to the bottom,which implies that surveys of surface water are not enough to determine the microplastic contamination for deep water reservoirs.In the surface water,the microplastic abundance in the Han Reservoir was lower than that in the Dan Reservoir(p<0.05),but microplastic abundance did not differ significantly in the intermediate and bottom water.Tributaries were one of the main sources of microplastics for Han Reservoir but not for Dan Reservoir.Agricultural cultivation in the hydro-fluctuation belt might be an important source of microplastics in the Dan Reservoir,which should be given additional attention.The results of this study can provide valuable information for developing microplastic sampling strategies in deep water reservoirs.Further studies are recommended to investigate the process through which microplastics in the hydro-fluctuation belt enter the reservoir and the sinking behavior of microplastics in the reservoir. | Li Lin Xiong Pan Sheng Zhang Danwen Li Wenliang Zhai Zhen Wang Jingxiang Tao Changqing Mi Qingyun Li John C.Crittenden | 2021 | Journal of Environmental Sciences2021，33，4： | 13 |
| 10 | Macrophage migration inhibitory factor stimulated by He/icobacter py/oriincreases proliferation of gastric epithelial cells显示文摘AIM: Helicobacter pylori (H pylori) is associated with increased gastric inflammatory and epithelial expression of macrophage migration inhibitory factor (MIF) and gastric epithelial cell proliferation. This study aimed at determining whether H pylori directly stimulates release of MIF in monocytes, whether the cay pathogenicity island (PAI) is involved for this function, and whether MIF stimulated by H pylori increases gastric epithelial cell proliferation in vitro.METHODS: A cytotoxic wild-type H pylori strain (TN2),its three isogenic mutants (TN2△cag, TN2△cagA and TN2△cagE) were co-cultured with cells of a human monocyte cell line, THP-1, for 24 h at different organism/cell ratios. MIF in the supernatants was measured by an ELISA. Cells of a human gastric cancer cell line, MKN45,were then co-cultured with the supernatants, with and without monoclonal anti-MIF antibody for 24 h. The cells were further incubated for 12 h after addition of 3H-thymidine, and the levels of incorporation of 3H-thymidine were measured with a liquid scintillation counter.RESULTS: The wild-type strain and the isogenic mutants,TN2△cagA and TN2△cagE, increased MIF release at organism/cell ratios of 200/1 and 400/1, but not at the ratios of 50/1 and 100/1. However, the mutant TN2△cag did not increase the release of MIF at any of the four ratios.3H-thymidine readings for MKN-45 cells were significantly increased with supernatants derived from the wild-type strain and the mutants TN2△cagA and TN2△cagE, but not from the mutant TN2△cag. Moreover, in the presence of monoclonal anti-MIF antibody, the stimulatory effects of the wild-type strain on cell proliferation disappeared.CONCLUSION: H pylori stimulates MIF release in monocytes, likely through its cag PAI, but not related to cagA or cagE. H pylori-stimulated monocyte culture supernatant increases gastric cell proliferation, which is blocked by anti-MIF antibody, suggesting that MIF plays an important role in H pylori-induced gastric epithelial cell proliferation. | Harry Hua-Xiang Xia Shiu Kum Lam Annie O.O.Chan Marie Chia Mi Lin Hsiang Fu Kung Keiji Ogura Douglas E.Berg Benjamin Chun-Yu Wong | 2005 | World Journal of Gastroenterology2005，11，13： | 12 |
| 11 | Eigenvalue approximation from below using non-conforming finite elements显示文摘This is a survey article about using non-conforming finite elements in solving eigenvalue problems of elliptic operators,with emphasis on obtaining lower bounds. In addition,this article also contains some new materials for eigenvalue approximations of the Laplace operator,which include:1) the proof of the fact that the non-conforming Crouzeix-Raviart element approximates eigenvalues associated with smooth eigenfunctions from below;2) the proof of the fact that the non-conforming EQ rot1 element approximates eigenvalues from below on polygonal domains that can be decomposed into rectangular elements;3) the explanation of the phenomena that numerical eigenvalues λ 1,h and λ 3,h of the non-conforming Q rot1 element approximate the true eigenvalues from below for the L-shaped domain. Finally,we list several unsolved problems. | YANG YiDu 1 ,ZHANG ZhiMin 2 & LIN FuBiao 11 School of Mathematics and Computer Science,Guizhou Normal University,Guiyang 550001,China 2 Department of Mathematics,Wayne State University,Detroit,MI 48202,USA | 2010 | Science China Mathematics2010，53，1： | 12 |
| 12 | 不同产蛋阶段蛋鸡卵黄前体物质生成的变化研究(英文)显示文摘目的:比较不同日龄蛋鸡血清雌激素的水平、肝脏雌激素受体基因和卵黄前体物生成相关基因表达量、'肝脏-血液-卵巢轴'中甘油三酯和胆固醇的含量和肝脏抗氧化能力的动态变化,揭示蛋鸡卵黄前体物生成随着年龄增长的变化规律。创新点:首次发现在蛋鸡衰老过程中雌激素作用衰退以及肝脏抗氧化能力降低致使肝脏中卵黄前体物合成下降,最终导致蛋鸡的产蛋性能下降。方法:取90、150、280和580日龄蛋鸡各10只,检测血清中雌激素水平、肝脏雌激素受体基因表达水平、肝脏中卵黄前体物质合成和脂质代谢相关基因表达水平、'肝脏-血液-卵巢轴'中甘油三酯和胆固醇的含量及肝脏抗氧化能力,揭示蛋鸡卵黄前体物生成在衰老过程中的变化规律。结论:在蛋鸡衰老过程中,血清雌激素水平、肝脏雌激素受体基因和卵黄前体物质合成相关基因表达量降低,肝脏抗氧化能力降低,引起肝脏合成甘油三酯的能力下降,最终导致卵黄前体物质合成能力降低。 | Xing-ting LIU Xin LIN Yu-ling MI Wei-dong ZENG Cai-qiao ZHANG | 2018 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018，19，5： | 11 |
| 13 | Blood perfusion of the contralateral testis evaluated with contrast-enhanced ultrasound in rabbits with unilateral testicular torsion显示文摘The changes of blood perfusion of contralateral testis after unilateral testicular torsion remain controversial.In this study,28 New Zealand white male rabbits were randomly divided into five groups.Group A(n=8),the control group,underwent a sham operation on the unilateral testis without inducing testicular torsion.In groups B,C,and D(n=5 each),unilateral testicular torsion was induced,and,after 3,6 or 24 h,respectively,detorsion was performed.In group E(n=5),permanent unilateral testicular torsion was applied.Contrast-enhanced ultrasound was used to observe the blood perfusion of the contralateral testis at the following stages:pre-torsion(preopration),immediately post-torsion(postopration),pre-detorsion,immediately post-detorsion,and late-stage post-detorsion(6-12 h post-detorsion in groups B-D)or at a similar time point(15-21 h post-torsion in group E).Time-intensity curves were generated,and the following parameters were derived and analyzed:arrival time,time to peak intensity,peak intensity,and half-time of the descending peak intensity.The analysis revealed that blood perfusion of the contralateral testis increased immediately after testicular torsion on the opposite side(P<0.05),which increased with prolonged testicular torsion of the other testis.This research demonstrated that contrast-enhanced ultrasound was valuable in evaluating blood perfusion of the contralateral testis after unilateral testicular torsion. | Lin Chen Wei-Wei Zhan Zhou-Jun Shen Wen-Bin Rui Chen Lv Man Chen Jian-Qiao Zhou Ping Zhou Mi Zhou Ying Zhu | 2009 | Asian Journal of Andrology2009，11，2： | 10 |
| 14 | Small-volume chylous ascites after laparoscopic radical gastrectomy for gastric cancer:Results from a large population-based sample显示文摘AIM:To report the incidence and potential risk factors of small-volume chylous ascites(SVCA)following laparoscopic radical gastrectomy(LAG).METHODS:A total of 1366 consecutive gastric cancer patients who underwent LAG from January 2008 to June 2011 were enrolled in this study.We analyzed the patients based on the presence or absence of SVCA.RESULTS:SVCA was detected in 57(4.17%)patients,as determined by the small-volume drainage(range,30-100 m L/24 h)of triglyceride-rich fluid.Both univariate and multivariate analyses revealed that the total number of resected lymph nodes(LNs),No.8 or No.9 LN metastasis and N stage were independent risk factors for SVCA following LAG(P<0.05).Regarding hospital stay,there was a significant difference between the groups with and without SVCA(P<0.001).The 3-year disease-free and overall survival rates of the patients with SVCA were 47.4%and 56.1%,respectively,which were similar to those of the patients without SVCA(P>0.05).CONCLUSION:SVCA following LAG developed significantly more frequently in the patients with≥32harvested LNs,≥3 metastatic LNs,or No.8 or No.9LN metastasis.SVCA,which was successfully treated with conservative management,was associated with a prolonged hospital stay but was not associated with the prognosis. | Jun Lu Zhen-Quan Wei Chang-Ming Huang Chao-Hui Zheng Ping Li Jian-Wei Xie Jia-Bin Wang Jian-Xian Lin Qi-Yue Chen Long-Long Cao Mi Lin | 2015 | World Journal of Gastroenterology2015，21，8： | 10 |
| 15 | MiR-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1显示文摘糖尿病和许多另外的新陈代谢症候群是仔细与肥胖有关。揭示胖免职的内在的机制,越来越多的研究在 adipocytes 开发期间正在集中于 miRNAs 的功能。以前的研究 haveproved 那出 miR-15a/b 戏在多重生理的过程的重要角色;然而,他们的功能在 adipogenesisremain 期间不清楚。揭示这,我们在猪的 pre-adipocyte 在 adipogenesis 期间检测了 miR-15a/b 的表示侧面,并且发现那他们层次在 adipocyte 区别的早阶段增加了并且在白天 4 .Moreover 以后落下的表示,在猪的 pre-adipocytes 的 miR-15a/b 的在表示上支持了 adipocyte 区别, miR-15a/b 的类脂化合物 accumulation.Target 基因被预言并且检验,它表明 Forkhead 盒子蛋白质 O1 ( FoxO1 )是目标 geneof miR-15a/b 。表示水平由 miR-15a/b 在表示上引起了的 FoxO1 的抑制在 adipogenesis.Thus 上有积极效果,我们断定 miR-15a/b 经由镇压在猪的 pre-adipocyte 支持 adipogenesis FoxO1。 | Peiyue Dong Yin Mai Zhenyu Zhang Lin Mi Guofang Wu Guiyan Chu Gongshe Yang Shiduo Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，7： | 6 |
| 16 | Preparation of Mg-Li alloys by electrolysis in molten salt at low temperature显示文摘A new technology for preparation of low cost Mg-Li alloys was studied. The alloys were prepared by electrolysis in molten LiCl-KCl (weight ratio is 1:1) electrolyte with Mg rod severing as the consumed cathode. Main factors that affect current efficiency were investigated, and optimal electrolysis parameters were obtained. Mg-Li alloys with low lithium content (about 25%) were prepared by the unique method of a higher post-thermal treatment temperature after electrolysis at low temperature. The results showed that the electrolysis can be carried out at low temperature, which resulted in reducing preparation cost due to energy saving.The new technology for the preparation of Mg-Li alloy by electrolysis in molten salt was proved to be feasible. | Mi Lin Zhang Yong De Yan Zhi Yao Hou Lu An Fan Zeng Chen Ding Xiang Tang | 2007 | Chinese Chemical Letters2007，18，3： | 5 |
| 17 | Demographic Characteristics and Environmental Risk Factors Exposure of Birth Defects in Pregnant Women: A Population-based Study显示文摘Worldwide, the incidence of birth defects in low-income countries is 6.42%, while in middle-income and high-income countries it is 5.57% and 4.72%, respectively;approximately 303, 000 newborns die from birth defects each year. In China, the incidence of birth defects is about 5.6%, and around 8.14 million people have congenital disabilities, accounting for 9.6% of total disabled people[1]. Birth defect remains a major clinical and public health challenge because of its high fatality rate and protracted and severe sequela. | LIN Hong LUO Mi Yang LUO Jia You ZENG Rong LI Ya Mei DU Qi Yun FANG Jun Qun | 2019 | Biomedical and Environmental Sciences2019，32，1： | 5 |
| 18 | The protective effect of tetrahedral framework nucleic acids on periodontium under inflammatory conditions显示文摘Periodontitis is a common disease that causes periodontium defects and tooth loss.Controlling inflammation and tissue regeneration are two key strategies in the treatment of periodontitis.Tetrahedral framework nucleic acids can modulate multiple biological behaviors,and thus,their biological applications have been widely explored.In this study,we investigated the effect of tFNAs on periodontium under inflammatory conditions.Lipopolysaccharide and silk ligature were used to induce inflammation in vivo and in vitro.The results displayed that tFNAs decreased the release of pro-inflammatory cytokines and levels of cellular reactive oxygen species in periodontal ligament stem cells,which promoted osteogenic differentiation.Furthermore,animal experiments showed that tFNAs ameliorated the inflammation of the periodontium and protect periodontal tissue,especially reducing alveolar bone absorption by decreasing inflammatory infiltration and inhibiting osteoclast formation.These findings suggest that tFNAs can significantly improve the therapeutic effect of periodontitis and have the great potential significance in the field of periodontal tissue regeneration. | Mi Zhou Shaojingya Gao Xiaolin Zhang Tianxu Zhang Tao Zhang Taoran Tian Songhang Li Yunfeng Lin Xiaoxiao Cai | 2021 | Bioactive Materials2021，6，6： | 5 |
| 19 | Measurement of γ detector backgrounds in the energy range of 3-8 MeV at Jinping underground laboratory for nuclear astrophysics显示文摘The astrophysical reaction rate of the charged-particleinduced reaction is dominated by the cross section within the Gamow window.The total cross section σ(E)of a chargedparticle-induced reaction is known to drops steeply with decreasing energy owing to the Coulomb barrier in the entrance channel: | YangPing Shen Jun Su WeiPing Liu Gang Lian Lin Gan LvHua Qiao ShengQuan Yan Yong Zhou Qian Yue Zhi Zeng QingDong Hu YuHao Mi Wei Zhao | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，10： | 5 |
| 20 | Metal-organic frameworks nanoswitch:Toward photo-controllable endo/lysosomal rupture and release for enhanced cancer RNA interference显示文摘Endo/lysosomal escape and gene release are two critical bottlenecks in gene delivery.Herein,a novel photo-controllable metal-organic frameworks(MOFs)nanoswitch is rationally designed for enhancing small interfering RNA(siRNA)delivery.One single laser triggers the“off-to-on”switching of MOFs nanocomplexes,inducing significant siRNA release accompanied by rapid MOFs dissociation into protonatable 2-methylimidazalo and osmotic rupturing Zn2+ions,which cooperatively contribute to remarkable endo/lysosomal rupture(∼90%).The simultaneous endo/lysosomal rupture and release enable a high spatio-temporal control on RNA interference for effective cancer therapy.Notably,the“off-to-on”switching also activates fluorescence recovery for real-time monitoring siRNA delivery.The nanoswitch could easily be extended to deliver other therapeutic agents(e.g.,DNA,protein,anticancer drug)for overcoming endo/lysosomal entrapment. | Gan Lin Yang Zhang Long Zhang Junqing Wang Ye Tian Wen Cai Shangui Tang Chengchao Chu JiaJing Zhou Peng Mi Xiaoyuan Chen Gang Liu | 2020 | Nano Research2020，13，1： | 5 |
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