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| 1 | Hydroxysafflor yellow A suppresses inflammatory responses of BV2 microglia after oxygen–glucose deprivation显示文摘 | Jie Li Shenyang Zhang Mengru Lu Zhibin Chen Cong Chen Lijuan Han Meijuan Zhang Yun Xu | 2013 | Neuroscience Letters2013，，： | 2 |
| 2 | Dual role of MdSND1 in the biosynthesis of lignin and in signal transduction in response to salt and osmotic stress in apple显示文摘Clarifying the stress signal transduction pathway would be helpful for understanding the abiotic stress resistance mechanism in apple(Malus×domestica Borkh.)and could assist in the development of new varieties with high stress tolerance by genetic engineering.The key NAC transcription factor SND1,which is involved in the lignin biosynthesis process in apple,was functionally analyzed.The results of the stress treatments indicated that MdSND1 could be induced by salt,mannitol and ABA.Compared with wild-type GL-3 plants,MdSND1-overexpressing apple plants with greater antioxidant capacity and lignin were more resistant to salt and simulated osmotic stress,while RNAi plants were more vulnerable.Additionally,molecular experiments confirmed that MdSND1 could regulate the biosynthesis of lignin by activating the transcription of MdMYB46/83.Moreover,genes known to be involved in the stress signal transduction pathway(MdAREB1A,MdAREB1B,MdDREB2A,MdRD29A,and MdRD22)were screened for their close correlations with the expression of MdSND1 and the response to salt and osmotic stress.Multiple verification tests further demonstrated that MdSND1 could directly bind to these gene promoters and activate their transcription.The above results revealed that MdSND1 is directly involved in the regulation of lignin biosynthesis and the signal transduction pathway involved in the response to both salt and osmotic stress in apple. | Keqin Chen Yunna Guo Mengru Song Lifu Liu Hao Xue Hongyan Dai Zhihong Zhang | 2020 | Horticulture Research2020，7，1： | 2 |
| 3 | Collaborative assembly-mediated siRNA delivery for relieving inflammation-induced insulin resistance显示文摘Obesity plays a primary causative role in insulin resistance and hyperglycemia that contributes to type 2 diabetes.Excess lipid storage in the liver renders activation of the resident macrophages and chronic secretion of inflammatory mediators,therefore causing or aggravating insulin resistance.Herein,we develop collaborative assemblies using a“one-pot”synthesis method for macrophage-specific delivery of small interfering RNAs(siRNAs)that target the inflammatory proteins.Ternary nanocomplex(NC)composed of the siRNA molecule,a synthetic thiol-bearing methacrylated hyaluronic acid(sm-HA)and protamine forms through an electrostatic-driven physical assembly,which is chemically crosslinked to acquire the collaboratively assembled nanocapsule(cNC)concurrently.The obtained cNC displays significantly higher stability than NC.Functional moieties as flexible assembly units can be easily equipped on cNC for long circulation,active targeting,or controlled siRNA release.cNC-F decorated with folic acid,a macrophage-targeting ligand promotes the siRNA accumulation in the activated macrophages in the liver of the obese mouse model.cNC-F loaded with siRNA targeting inflammatory indicators efficiently control the macrophage inflammatory response by reducing the expression of the inflammatory proteins(>40%reduction)and ameliorating the insulin resistance symptoms of the obese mice. | Shiyang Shen Li Zhang Mengru Li Zhizi Feng Huixia Li Xiao Xu Shiqi Lin Ping Li Can Zhang Xiaojun Xu Ran Mo | 2020 | Nano Research2020，13，11： | 2 |
| 4 | Antibacterial evaporator based on reduced graphene oxide/polypyrrole aerogel for solar-driven desalination显示文摘Solar-driven water evaporation is a sustainable method to purify seawater.Nevertheless,traditional volumetric water-evaporation systems suffer from the poor sunlight absorption and inefficient light-to-thermal conversion.Also,their anti-bacterial and antifouling performances are crucial for the practical application.Herein,we introduce reduced graphene oxide(RGO)with broadband absorbance across the entire solar spectrum,and polypyrrole(PPy),an antibacterial polymer with efficient solar absorption and low thermal conductivity,to develop integrated RGO/PPy aerogel as both the solar absorber and evaporator for highly efficient solar-driven steam generation.As a result,the RGO/PPy aerogel shows strong absorption and good photothermal performance,leading to an evaporation rate of 1.44 kg·m^(−2)·h^(−1)and high salt rejection(up to 99.99%)for real seawater,with photothermal conversion efficiency>90%under one sun irradiation.The result is attributed to the localized heat at the air-water interface by the RGO/PPy and its porous nature with functional groups that facilitates the water evaporation.Moreover,the RGO/PPy demonstrates excellent durability and antibacterial efficiency close to 100%for 12 h,crucial characteristics for longterm application.Our well-designed RGO/PPy aerogel with efficient water desalination performance and antibacterial property provides a straightforward approach to improve the solar-driven evaporation performance by multifunctional materials integration,and offers a viable route towards practical seawater desalination. | Mengru Zhang Fan Xu Wenjie Liu Yaqi Hou Liyun Su Xin Zhang Ruihua Zhang Lijun Zhou Xiaomei Yan Miao Wang Xu Hou Yang Cao | 2023 | Nano Research2023，16，4： | 2 |
| 5 | Construction of nanofibrous scaffolds with interconnected perfusable microchannel networks for engineering of vascularized bone tissue显示文摘Vascularization and bone regeneration are two closely related processes during bone reconstruction.A three-dimensional(3D)scaffold with porous architecture provides a suitable microenvironment for vascular growth and bone formation.Here,we present a simple and general strategy to construct a nanofibrous poly(L-lactide)/poly(ε-caprolactone)(PLLA/PCL)scaffold with interconnected perfusable microchannel networks(IPMs)based on 3D printing technology by combining the phase separation and sacrificial template methods.The regular and customizable microchannel patterns within the scaffolds(spacings:0.4 mm,0.5 mm,and 0.6 mm;diameters:0.8 mm,1 mm,and 1.2 mm)were made to investigate the effect of microchannel structure on angiogenesis and osteogenesis.The results of subcutaneous embedding experiment showed that 0.5/0.8-IPMs(spacing/diameter=0.5/0.8)and 0.5/1-IPMs(spacing/diameter=0.5/1)scaffolds exhibited more vascular network formation as compared with other counterparts.After loading with vascular endothelial growth factor(VEGF),VEGF@IPMs-0.5/0.8 scaffold prompted better human umbilical vein endothelial cells(HUVECs)migration and neo-blood vessel formation,as determined by Transwell migration,scratch wound healing,and chorioallantoic membrane(CAM)assays.Furthermore,the microangiography and rat cranial bone defects experiments demonstrated that VEGF@IPMs-0.5/0.8 scaffold exhibited better performance in vascular network formation and new bone formation compared to VEGF@IPMs-0.5/1 scaffold.In summary,our results suggested that the microchannel structure within the scaffolds could be tailored by an adjustable caramel-based template strategy,and the combination of interconnected perfusion microchannel networks and angiogenic factors could significantly enhance vascularization and bone regeneration. | Jiani Gu Qianqian Zhang Mengru Geng Weizhong Wang Jin Yang Atta ur Rehman Khan Haibo Du Zhou Sha Xiaojun Zhou Chuanglong He | 2021 | Bioactive Materials2021，6，10： | 1 |
| 6 | DFT-assisted rational design of CoM_(x)P/CC(M=Fe,Mn,and Ni) as efficient electrocatalyst for wide pH range hydrogen evolution and oxygen evolution显示文摘Rational design of highly active transition-metal phosphides for electrocatalyzing overall water splitting in a wide pH range assisted by first-principle calculations can efficiently save the developing cost and hence is quite attractive.Under the guidance of density-functional theory(DFT)calculations that the introduction of dopants(Fe,Mn,and Ni)into CoP could promote the hydrogen evolution reaction(HER)performances,a series of binder-free CoM_(x)P/carbon cloth(CC;M=Fe,Mn,and Ni;x=0,0.05,0.2,0.5,and 1)were fabricated.Both experimental measurements and DFT calculations confirm the electronic modulation of dopants.DFT calculations further reveal that the modulated electronic structure promotes the electronic conductivity,favors the adsorption of key species,and consequently promotes the electrochemical performances.As predicted,the bimetallic phosphides demonstrate excellent HER performances in alkaline,acidic,and alkaline simulated seawater solutions and also deliver excellent oxygen evolution reaction(OER)performances,overwhelming the commercial RuO_(2).Benefiting from the modulated electronic structure and the hierarchical structure with massive CoFe0.05P zero-dimensional(0D)quantum dots anchored on two-dimensional(2D)N-doped porous carbon,CoFe0.05P delivered the best HER in four kinds of electrolytes(ƞ10 of 73 mV in an alkaline simulated seawater solution)and OER in two kinds of electrolytes(ƞ10 of 264 mV in an alkaline solution)with excellent stability of 45 h in the alkaline solution.The assembled CoFe0.05P/CC//CoFe0.05P/CC with the electrodes folded by 180°can still maintain a low cell potential of 1.62 V at 10 mA·cm^(−2).This work proves the feasibility of the reported rational design strategy of developing efficient electrocatalysts for overall water splitting in a wide pH range. | Xiangrui Zhang Chunyan Sun Shusheng Xu Mengru Huang Yi Wen Xue-Rong Shi | 2022 | Nano Research2022，15，10： | 1 |
| 7 | Bio-Based Trivalent Phytate:A Novel Strategy for Enhancing Fire Performance of Rigid Polyurethane Foam Composites显示文摘Biomass phytic acid has potential flame retardant value as the main form of phosphorus in plant seeds.In this study,phytate-based flame retardants aluminum phytate(PA-Al)and iron phytate(PA-Fe)were synthesized and characterized.Subsequently,they were introduced into rigid polyurethane foam(RPUF)as flame retardants by one-step water-blown method.The results indicated that RPUF/PA-Fe30 exhibited the highest char residue of 22.1 wt%,significantly higher than 12.4 wt%of RPUF.Cone calorimetry analysis showed that the total heat release(THR)of RPUF/PA-Al30 decreased by 17.0%and total smoke release(TSR)decreased by 22.0%compared with pure RPUF,which were the lowest,demonstrating a low fire risk and good smoke suppression.Thermogravimetric analysis-Fourier transform infrared spectrometer(TG-FTIR)implied the release intensity of flammable gases(hydrocarbons,esters)and toxic gases(isocyanate,CO,aromatic compounds,HCN)of composites was significantly reduced after the addition of PA-Fe.The analysis of char residue indicated that the RPUF composites formed a dense char layer with a high degree of graphitization after the addition of PA-Al/PA-Fe,endowing RPUF composites with excellent mass&heat transmission inhibition effect and fire resistance in the combustion process. | Bing Zhang Sujie Yang Mengru Liu Panyue Wen Xiuyu Liu Gang Tang Xiangrong Xu | 2022 | Journal of Renewable Materials2022，10，5： | 1 |
| 8 | Hydroxysafflor yellow A suppresses inflammatory responses of BV2 microglia after oxygen-glucose deprivation显示文摘 | Li Jie Zhang Shenyang Lu Mengru | 2013 | Neuroscience Letters2013，535，22： | 1 |
| 9 | Hydroxysafflor yellow A suppresses inflammatory responses of BV2 microglia after oxygen–glucose deprivation显示文摘 | Jie Li Shenyang Zhang Mengru Lu Zhibin Chen Cong Chen Lijuan Han Meijuan Zhang Yun Xu | 2013 | Neuroscience Letters2013，，： | 1 |
| 10 | The advantages of crosstalk during the evolution of the BZR1–ARF6–PIF4 (BAP) module∞显示文摘The BAP module,comprising BRASSINAZOLE RESISTANT 1(BZR1),AUXIN RESPONSE FACTOR 6(ARF6),and PHYTOCHROME‐INTERACTING FACTOR 4(PIF4),functions as a molecular hub to orchestrate plant growth and development.In Arabidopsis thaliana,components of the BAP module physically interact to form a complex system that integrates light,brassinosteroid(BR),and auxin signals.Little is known about the origin and evolution of the BAP module.Here,we conducted comparative genomic and transcriptomic analyses to investigate the evolution and functional diversification of the BAP module.Our results suggest that the BAP module originated in land plants and that theζ,ε,andγwhole‐genome duplication/triplication events contributed to the expansion of BAP module components in seed plants.Comparative transcriptomic analysis suggested that the prototype BAP module arose in Marchantia polymorpha,experienced stepwise evolution,and became established as a mature regulatory system in seed plants.We developed a formula to calculate the signal transduction productivity of the BAP module and demonstrate that more crosstalk among components enables higher signal transduction efficiency.Our results reveal the evolutionary history of the BAP module and provide insights into the evolution of plant signaling networks and the strategies employed by plants to integrate environmental and endogenous signals. | Runjie Diao Mengru Zhao Yannan Liu Zhenhua Zhang Bojian Zhong | 2023 | Journal of Integrative Plant Biology2023，65，12： | 0 |
| 11 | Shunxin decoction(顺心组方) improves diastolic function in rats with heart failure with preserved ejection fraction induced by abdominal aorta constriction through cyclic guanosine monophosphate-dependent protein kinase Signaling Pathway显示文摘OBJECTIVE: To determine whether Shunxin decoction(顺心组方) improves diastolic function in rats with heart failure with preserved ejection fraction(HFp EF) by regulating the cyclic guanosine monophosphatedependent protein kinase(c GMP-PKG) signaling pathway. METHODS: Except for control group 8 and sham surgery group 8, the remaining 32 male Sprague-Dawlay rats were developed into HFp EF rat models using the abdominal aorta constriction method. These rats in the HFp EF model were randomly divided into the model group, the Shunxin high-dose group, the Shunxin lowdose group, and the Qiliqiangxin capsule group. The three groups received high-dose Shunxin decoction, lowdose Shunxin decoction, and Qiliqiangxin capsule by gavage, respectively, for 14 d. After the intervention, the diastolic function of each rat was evaluated by testing E/A, heart index, hematoxylin-eosin staining, Masson, myocardial ultrastructure, and N-terminal pro-brain natriuretic peptide(NT-pro BNP). The Bioinformatics Analysis Tool for Molecular Mechanism of Traditional Chinese Medicine(BATMAN-TCM) software was used to predict targets for which Shunxin decoction acts on the c GMP-PKG pathway. Natriuretic peptide receptor A(NPRA) and guanylate cyclase(GC) were detected by immunohistochemistry, and e NOS, phosphodiesterase 5A(PDE5A), and c GMP-dependent protein kinase 1(PKG I) were determined by Western blotting. RESULTS: Compared to the model group, the thickness of the interventricular septum at the end of diastole(IVSd) and the thickness of the posterior wall at the end of diastole(PWd) of the Shunxin decoction high-dose group, Shunxin decoction low-dose group, and Qiliqiangxin capsule group were all significantly reduced(P < 0.01). Furthermore, Shunxin decoction high-dose group E/A value was decreased(P < 0.01). Compared to the model group, the expression of NPRA and GC increased in the Shunxin decoction low-dose group and the Qiliqiangxin capsule group(P < 0.01). Compared to the model group, the expressions of e NOS and PKG I increased(P < 0.05) in the Shunxin decoction high-dose group. The expression of PDE5A expression decreased in the myocardium of the Shunxin decoction high-dose group, Shunxin decoction low-dose group, and Qiliqiangxin capsule group compared to the model group(P < 0.01). CONCLUSIONS: Shunxin decoction can improve diastolic function in rats with HFp EF. It increases the expression of NPRA, GC, and e NOS in the myocardial cell c GMP-PKG signaling pathway, upregulates c GMP expression, decreases PDE5A expression to reduce the c GMP degradation. Thus, the c GMP continually stimulates PKG I, reversing myocardial hypertrophy and improving myocardial compliance in HFp EF rats. | ZHANG Jiaying WEI Xiangxiang LI Xuefeng YUAN Yang DOU Yinghuan SHI Yanbin XIE Ping ZHOU Mengru ZHAO Junnan LI Miao ZHANG Shuwen ZHU Rui TIAN Ying TAN Hao TIAN Feifei | 2022 | Journal of Traditional Chinese Medicine2022，42，5： | 0 |
| 12 | Advances in Research of Components,Pharmacological Activity and Clinical Application of Vicatia thibetica de Boiss显示文摘Vicatia thibetica de Boiss is a Tibetan medicinal herb and mainly contains chemical components such as flavonoids,β-sitosterol and ferulic acid.It has good pharmacological effects such as anti-inflammatory,analgesic,anti-fatigue,anti-oxidation,anti-aging and enhancing immunity.Based on relevant domestic and foreign literature,this paper comprehensively reviews the main components,pharmacological activity and clinical prescription application of V.thibetica de Boiss,to provide a reference for the in-depth research and comprehensive development and utilization of V.thibetica de Boiss. | Mengru ZHANG Jianli ZHAO Bowen ZHENG Qingwei YAN Xu JI Gengsang Fangyun SUN | 2022 | Medicinal Plant2022，13，6： | 0 |
| 13 | Fast extraction of winter wheat planting area in Huang-Huai-Hai Plain using high-resolution satellite imagery on a cloud computing platform显示文摘To extract regional winter wheat planting area using higher-resolution satellite imagery still faces many challenges due to large data size and long processing time in traditional remote sensing classification.Google Earth Engine(GEE),a cloud computing analysis platform based on global geospatial analysis,provides a new opportunity for rapid analysis of remote sensing data.In this study,high-quality Landsat-8 imagery was used to extract the winter wheat planting area from the Huang-Huai-Hai Plain in China.The random forest algorithm was used to identify and map the winter wheat sown in 2019 and harvested in 2020,and Sentinel-2 imagery was used to verify the results.The spectral indices,texture,and terrain features of the image were derived,and their contribution to the classification accuracy of winter wheat was evaluated by scoring.Then the top nine features were selected to form an optimal feature subset.Comparing the set of thirty-four features and the optimized feature subset as the input variables of the random forest classifier,the results show that the accuracy difference between the two feature classification schemes is small,but the classification effect of all feature sets is slightly better than the optimal feature subset.The overall classification accuracy of sample plots verification was 86%-95%,the Kappa coefficient was between 0.7 and 0.85,and the percentage error of the total area was 5.42%.The research demonstrates a reliable method for mapping a wide range of winter wheat planting area,and provides a good prospect for exploring the precise mapping of other crops,which is of great significance to crop monitoring and agricultural development. | Dongyan Zhang Mengru Zhang Fenfang Lin Zhenggao Pan Fei Jiang Liang He Hang Yang Ning Jin | 2022 | International Journal of Agricultural and Biological Engineering2022，15，1： | 0 |
| 14 | Assembly of N-and P-functionalized carbon nanostructures derived from precursor-defined ternary copolymers for high-capacity lithiumion batteries显示文摘Synthesis of new carbon nanostructures with tunable properties is vital for precisely regulating electrochemical performance in the wide applications.Herein,we report a novel approach for the oxidative polymerization of N-and P-bearing copolymers from the self-assembly of three different monomers(aniline,pyrrole,and phytic acid),and further prepare the respective carbon nanostructures with relatively consistent N dopant(6.2%–8.0%,atom)and varying P concentrations(0.4%–2.8%,atom)via controllable pyrolysis.The impacts of phytic acid addition on the compositional,structural,and morphological evolution of the copolymers and the resulting nanocarbons are well studied through a spectrum of characterizations including N2 sorption,Fourier transform infrared spectroscopy,gel permeation chromatograph,scanning/transmission electron microscopy,and X-ray photoelectron spectroscopy.Gradual fragmentation of the nanosphere structures is evidenced with increasing addition of phytic acid,leading to different nanostructures from hollow nanospheres to 3D aggregates.Nanocarbons decorated with N and P dopants from pyrolysis are further utilized as anode materials in lithium-ion batteries,demonstrating enhanced electrochemical performance,i.e.,a reversible capacity of 380 mAhg^(-1)at 2 Ag^(-1)for NPC-0.5 during 200 cycles.The superior performance originates from the balanced porosity,and appropriate concentrations of P and pyrrolic N,thus pointing the direction for designing high-performance anode materials. | Luyao Guo Mengru Wang Ronghe Lin Jiaxin Ma Shuanghao Zheng Xiaoling Mou Jun Zhang Zhong-Shuai Wu Yunjie Ding | 2023 | Chinese Journal of Chemical Engineering2023，53，1： | 0 |
| 15 | Role of CD36 in central nervous system diseases显示文摘CD36 is a highly glycosylated integral membrane protein that belongs to the scavenger receptor class B family and regulates the pathological progress of metabolic diseases.CD36 was recently found to be widely expressed in various cell types in the nervous system,including endothelial cells,pericytes,astrocytes,and microglia.CD36 mediates a number of regulatory processes,such as endothelial dysfunction,oxidative stress,mitochondrial dysfunction,and inflammatory responses,which are involved in many central nervous system diseases,such as stroke,Alzheimer’s disease,Parkinson’s disease,and spinal cord injury.CD36 antagonists can suppress CD36 expression or prevent CD36 binding to its ligand,thereby achieving inhibition of CD36-mediated pathways or functions.Here,we reviewed the mechanisms of action of CD36 antagonists,such as Salvianolic acid B,tanshinone IIA,curcumin,sulfosuccinimidyl oleate,antioxidants,and small-molecule compounds.Moreover,we predicted the structures of binding sites between CD36 and antagonists.These sites can provide targets for more efficient and safer CD36 antagonists for the treatment of central nervous system diseases. | Min Feng Qiang Zhou Huimin Xie Chang Liu Mengru Zheng Shuyu Zhang Songlin Zhou Jian Zhao | 2024 | Neural Regeneration Research2024，19，3： | 0 |
| 16 | Study on the evaluation method of diffuse radiation models——taking 5 typical cities in China as examples显示文摘Diffuse solar radiation models play an extremely important role in solar photothermal utilization,resource assess-ment and energy consumption simulation,etc.The accuracy of these diffuse solar radiation models usually need to be evaluated by various statistical parameters.Among these statistical parameters,the Global Performance In-dex(GPI)has been extensively employed in recent years because of its comprehensiveness and wide applicability.This paper takes five cities in China as representatives of 5 typical climate regions,and 12 solar scattered radia-tion models are fitted with the meteorological data of 5 cities.Based on the comparative analysis of the existing GPI calculation methods,this paper points out that there are some defects in the existing GPI,and modifies the existing GPI based on the comprehensive consideration of statistical parameters,normalization preprocessing of statistical parameters,unified evaluation direction of parameters,weight redistribution of statistical parameters,and adjustment of extreme coefficient.12 types of new GPI are established in this paper,and the performance of diffuse solar radiation models are compared based on these GPI.The rationality of GPI corrective measures is analyzed by means of the method reasonable index(MRI).The results show that the GPI calculation method(N10)which takes five corrective measures has the best performance,and the accuracy of the existing GPI can be improved by 13.33 to 65%. | Gang Su Shuangyang Zhang Wanxiang Yao Mengru Hu Haodong Hao | 2023 | Energy and Built Environment2023，4，2： | 0 |
| 17 | WATER POLLUTION AND AGRICULTURE:MULTI-POLLUTANT PERSPECTIVES显示文摘Agriculture is an important cause of multiple pollutants in water.With population growth and increasing food demand,more nutrients,plastics,pesticides,pathogens and antibiotics are expected to enter water systems in the 21st century.As a result,water science has been shifting from singlepollutant to multi-pollutant perspectives for large-scale water quality assessments.This perspective paper summarizes and discusses four main highlights related to water pollution and agriculture from the multi-pollutant perspective.These highlights reveal the spatial and temporal distribution and main sources of multiple pollutants in waters.Based on the highlights,a scientific agenda is proposed to prioritize solutions for sustainable agriculture(UN Sustainable Development Goal 2)and clean water(UN Sustainable Development Goals 6 and 14).This agenda points out that when formulating solutions for water pollution,it is essential to take into account multiple pollutants and their interactions beyond biogeochemistry. | Mengru WANG Qi ZHANG Yanan LI Mirjam P.BAK Sijie FENG Carolien KROEZE Fanlei MENG Ilaria MICELLA Vita STROKAL Aslhan URAL-JANSSEN Maryna STROKAL | 2023 | Frontiers of Agricultural Science and Engineering2023，10，4： | 0 |
| 18 | GREEN AGRICULTURE AND BLUE WATER IN CHINA:REINTEGRATING CROP AND LIVESTOCK PRODUCTION FOR CLEAN WATER显示文摘Crop and livestock production are essential to maintain food security.In China,crop and livestock production were integrated in the past.Today,small backyard systems are still integrated but the larger livestock farms are landless and largely geographically separated from crop production systems.As a result,there is less recycling of animal manures and there are lower nutrient use efficiencies in the Chinese food production systems.This,in turn,results in considerable losses of nutrients,causing water pollution and harmful algal blooms in Chinese lakes,rivers and seas.To turn the tide,there is a need for agricultural“green”development for food production through reintegrating crop and livestock production.An additional wish is to turn the Chinese water systems“blue”to secure clean water for current and future generations.In this paper,current knowledge is summarized to identify promising interventions for reintegrating crop and livestock production toward clean water.Technical,social,economic,policy and environmental interventions are addressed and examples are given.The paper highlights recommended next steps to achieve“green”agriculture and“blue”water in China. | Maryna STROKAL Annette BGJANSSEN Xinping CHEN Carolien KROEZE Fan LI Lin MA Huirong YU Fusuo ZHANG Mengru WANG | 2021 | Frontiers of Agricultural Science and Engineering2021，8，1： | 0 |
| 19 | Nitrogen deposition suppresses fungal biomass and oxidase activity in faeces of the millipede Spirobolus formosae in a temperate forest显示文摘Atmospheric nitrogen(N)deposition has increased dramatically since the industrial revolution due to human activities.In terrestrial ecosystems,excess nitrogen inputs can greatly affect soil chemical properties,plant growth,and activities of soil microbes and fauna.Millipedes can fragment and consume large quantities of litter,and they regulate nutrient cycling and affect soil fertility through excretion of faeces.Many soil fauna graze on the faeces of millipedes as a part of the soil food web.The decomposition and stabilization of these millipede faeces are especially important in soil carbon dynamics and nutrient cycling,and these processes rely heavily upon microbial activity.However,very few studies have investigated how microbial community structure and oxidase activity of millipede faeces respond to climate change,especially N deposition.Therefore,we designed a microcosm study to investigate this question,which included two treatments,N addition treatment and control(without N addition).We found that:(i)microbial community structure in millipede faeces was altered and the biomass of fungi and actinomycetes in faecal pellets were significantly reduced after N addition,but bacteria still dominated in millipede faeces after N addition,(ii)oxidase activity was suppressed in response to N addition,and(iii)microbial community structure and oxidase activities were significantly correlated to organic carbon and dissolved total nitrogen of faeces.All these changes suggest that millipede excretion activities under nitrogen deposition contribute to carbon stabilization and reduction in greenhouse gas emission owing to the significant role of fungi and associated oxidase in carbon mineralization.It is noteworthy to pay more attention to the function of saprotrophic invertebrates in future N deposition studies. | Mengru Wang Shenglei Fu Hongzhi Zhang Meina Wang Haixiang Xu Leilei Shi | 2019 | Soil Ecology Letters2019，1，1： | 0 |
| 20 | A mutation in CsKTN1 for the Katanin p60 protein results in miniature plant in cucumber,Cucumis sativus L.显示文摘Katanin,a microtubule shearing protein,plays an important role in plant architecture formation.However,little is known about its mechanisms in regulating plant architecture in cucumber.In the present study,through EMS mutagenesis,we identified a novel micro-plant(mp)mutant in the North China type inbred line CCMC that may be of value for cucumber breeding.The size and number of stem cells were altered in the mp mutant.Through bulked segregant analysis(BSA)sequencing approach combined with genetic mapping,the mp locus was delimited to an interval of 130.9-kb.Multiple lines of evidence suggested that the mp mutation is due to a single nucleotide polymorphism in Csa7G435510 that is predicted to encode the Katanin p60 subunit protein(CsKTN1).The expression levels of CsKTN1 decreased significantly in all tissues except the tendril of mp mutant.Subcellular localization showed that both wild-type and mutant CsKTN1 proteins were located in cell membrane,cytoplasm and nucleus of tobacco leaf cells.The mutant protein lost part of its ability to bind and shear microtubule in vitro.These findings provide new insight into the regulatory function of microtubule-shearing protein,Katanin p60,in plant architecture of cucumber. | MengFei Song WenYuan Fu YuHui Wang Feng Cheng MengRu Zhang JinFeng Chen QunFeng Lou | 2022 | Vegetable Research2022，2，1： | 0 |
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