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| 1 | Chrysanthemum WRKY15-1 promotes resistance to Puccinia horiana Henn. via the salicylic acid signaling pathway显示文摘Chrysanthemum white rust disease,which is caused by the fungus Puccinia horiana Henn.,severely reduces the ornamental quality and yield chrysanthemum.WRKY transcription factors function in the disease-resistance response in a variety of plants;however,it is unclear whether members of this family improve resistance to white rust disease in chrysanthemum.In this study,using PCR,we isolated a WRKY15 homologous gene,CmWRKY15-1,from the resistant chrysanthemum cultivar C029.Real-time quantitative PCR(RT-qPCR)revealed that CmWRKY15-1 exhibited differential expression patterns between the immune cultivar C029 and the susceptible cultivar Jinba upon P.horiana infection.In addition,salicylic acid(SA)treatment strongly induced CmWRKY15-1 expression.Overexpression of CmWRKY15-1 in the chrysanthemum-susceptible cultivar Jinba increased tolerance to P.horiana infection.Conversely,silencing CmWRKY15-1 via RNA interference(RNAi)in C029 increased sensitivity to P.horiana infection.We also determined that P.horiana infection increased both the endogenous SA content and the expression of salicylic acid biosynthesis genes in CmWRKY15-1-overexpressing plants,whereas CmWRKY15-1 RNAi plants exhibited the opposite effects under the same conditions.Finally,the transcript levels of pathogenesis-related(PR)genes involved in the SA pathway were positively associated with CmWRKY15-1 expression levels.Our results demonstrated that CmWRKY15-1 plays an important role in the resistance of chrysanthemum to P.horiana by influencing SA signaling. | Mengmeng Bi Xueying Li Xin Yan Di Liu Ge Gao Pengfang Zhu Hongyu Mao | 2021 | Horticulture Research2021，8，1： | 9 |
| 2 | Similar or different: the same Spiro-core but different alkyl chains with apparently improved device performance of perovskite solar cells显示文摘By intelligently utilizing the odd-even effect existing in the melting points of alkanes as presented in the basic textbook of Organic Chemistry, different alkoxy groups were introduced to modify the structure of commercial Spiro-OMeTAD to give new Spiro derivatives of Spiro-OEtTAD, Spiro-OPrTAD, Spiro-OiPrTAD and Spiro-OBuTAD, with the aim to adjust the molecular packing status in perovskite solar cells as hole transporting compounds. Excitedly, with the introduction of ethoxy groups instead of the methoxy ones in Spiro-OMeTAD, Spiro-OEtTAD-based perovskite solar cells demonstrated the highest device performance of 20.16%, higher than that of Spiro-OMeTAD(18.64%). | Fan Liu Shiqing Bi Xiaorui Wang Xuanye Leng Mengmeng Han Baoda Xue Qianqian Li Huiqiong Zhou Zhen Li | 2019 | Science China Chemistry2019，62，6： | 2 |
| 3 | Gene Expression in Benzene-exposed Workers by Microarray Analysis of Peripheral Mononuclear Blood Cells:Induction and Silencing of CYP4F3A and Regulation of DNA-dependent Protein Kinase Catalytic Subunit in DNA Double Strand Break Repair显示文摘 | BI Yongyi LI Yuhong KONG Mengmeng | | 0，，1： | 1 |
| 4 | Synthesis and electromagnetic wave absorption performances of a novel(Mo_(0.25)Cr_(0.25)Ti_(0.25)V_(0.25))_(3)AlC_(2)high-entropy MAX phase显示文摘Herein,a novel kind of high-entropy MAX phases,(Mo_(0.25)Cr_(0.25)Ti_(0.25)V_(0.25))_(3)AlC_(2)powders were success-fully synthesized by a newly proposed two-step solid state reaction process.The oxidation experiments demonstrate that the oxidation products of Al_(2)Mo_(3)O_(12) and rutile TiO 2 are formed at about 600 and 800℃,respectively.Besides,the dielectric and electromagnetic(EM)wave absorption properties of(Mo_(0.25)Cr_(0.25)Ti_(0.25)V_(0.25))_(3)AlC_(2)powders and those after oxidation at different temperatures were also exam-ined.The results show that the as-synthesized(Mo_(0.25)Cr_(0.25)Ti_(0.25)V_(0.25))_(3)AlC_(2)powders possess excellent EM wave absorption performances with the minimum reflection loss(RL)of-45.80 dB(at 1.7 mm thickness)and the maximum effective absorption bandwidth(E AB)of 3.6 GHz(at 1.5 mm thickness).After oxidation at 400-800℃,due to the coupling of conductivity loss and polarization loss,(Mo_(0.25)Cr_(0.25)Ti_(0.25)V_(0.25))_(3)AlC_(2)powders can retain good EM wave absorption properties in a certain frequency range.In this paper,the effects of oxidation on EM wave absorption properties of high-entropy MAX phases were systematically investigated for the first time.This work manifests that high-entropy MAX phases are promising EM wave absorbing candidates and can maintain good EM wave absorption performances after oxidation. | Linjing Qiao Jianqiang Bi Guandong Liang Chen Liu Zhuangzhuang Yin Yao Yang Hongyi Wang Shaoyin Wang Mengmeng Shang Weili Wang | 2023 | Journal of Materials Science & Technology2023，，6： | 1 |
| 5 | Multifaceted roles of LhWRKY44 in promoting anthocyanin accumulation in Asiatic hybrid lilies (Lilium spp.)显示文摘The Asiatic hybrid lily(Lilium spp.)is a horticultural crop with high commercial value and diverse anthocyanin pigmentation patterns.However,the regulatory mechanism underlying lily flower color has been largely unexplored.Here,we identified a WRKY transcription factor from lily tepals,LhWRKY44,whose expression was closely associated with anthocyanin accumulation.Functional verification indicated that LhWRKY44 positively regulated anthocyanin accumulation.LhWRKY44 physically interacted with LhMYBSPLATTER and directly bound to the LhMYBSPLATTER promoter,which enhanced the effect of the LhMYBSPLATTER-LhbHLH2 MBW complex activator on anthocyanin accumulation.Moreover,EMSA and dual-luciferase assays revealed that LhWRKY44 activated and bound to the promoters of gene LhF3H and the intracellular anthocyanin-related glutathione S-transferase gene LhGST.Interestingly,our further results showed that LhWRKY44 participated in light and drought-induced anthocyanin accumulation,and improved the drought tolerance in lily via activating stress-related genes.These results generated a multifaceted regulatory mechanism for the LhWRKY44-meditaed enhancement by the environmental signal pathway of anthocyanin accumulation and expanded our understanding of the WRKY-mediated transcriptional regulatory hierarchy modulating anthocyanin accumulation in Asiatic hybrid lilies. | Mengmeng Bi Rui Liang Jiawen Wang Yuxiao Qu Xin Liu Yuwei Cao Guoren He Yue Yang Panpan Yang Leifeng Xu Jun Ming | 2023 | Horticulture Research2023，10，9： | 0 |
| 6 | Dual inhibition of glucose uptake and energy supply synergistically restrains the growth and metastasis of breast cancer显示文摘Metastatic breast cancer(MBC) is one of the most common and knotty diseases in female population which could place them in a life-threatening condition. For malignant proliferation and migration, cancer cells require a large amount of glucose and energy to meet the demand of rapid metabolism. Hence,efficiently diminishing the utilization of energy substances by cancer cells is emerging as validated therapeutic strategies for cancer therapy. Herein, a nanoplatform with dual-inhibition of glucose uptake and oxidative phosphorylation(OXPHOS) was designed, which consisted of albendazole(ABZ) and atovaquone(ATO) by simple carrier-free self-assembling. The introduction of ABZ could evidently decrease glucose uptake to reduce the main “energy fuel” of cancer cells. Meanwhile, as a blocker of OXPHOS, ATO would reduce adenosine triphosphate(ATP) production and ameliorate hypoxia microenvironment by suppressing mitochondrial respiratory chain. Under such dual inhibition of energy metabolism, AA NPs exerted synergistic energy exhaustion effect and outstanding hypoxia improvement function, efficiently inhibiting tumor growth and metastasis. This research not only illustrates the feasibility of energy metabolism therapy by co-inhibiting glucose uptake and OXPHOS, but also provides an ingenious tactic to diminish metastasis during MBC treatment. | Yuan Xu Liling Huang Yuyang Bi Qi Song Mengmeng Zhang Lingfeng Zhang Tianjiao Zhou Lei Xing Hulin Jiang | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
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