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| 1 | Availability-based simulation and optimization modeling framework for open-pit mine truck allocation under dynamic constraints显示文摘We present a novel system productivity simulation and optimization modeling framework in which equipment availability is a variable in the expected productivity function of the system. The framework is used for allocating trucks by route according to their operating performances in a truck-shovel system of an open-pit mine, so as to maximize the overall productivity of the fleet. We implement the framework in an originally designed and specifically developed simulator-optimizer software tool. We make an application on a real open-pit mine case study taking into account the stochasticity of the equipment behavior and environment. The total system production values obtained with and without considering the equipment reliability, availability and maintainability (RAM) characteristics are compared. We show that by taking into account the truck and shovel RAM aspects, we can maximize the total production of the system and obtain specific information on the production availability and productivity of its components. | Mena Rodrigo Zio Enrico Kristjanpoller Fredy Arata Adolfo | 2013 | International Journal of Mining Science and Technology2013，23，1： | 8 |
| 2 | Atmosphere-ionosphere response to the M9 Tohoku earthquake revealed by multiinstrument space-borne and ground observations:Preliminary results显示文摘We retrospectively analyzed the temporal and spatial variations of four different physical parameters characterizing the state of the atmosphere and ionosphere several days before the M9 Tohoku,Japan earthquake of March 11,2011.The data include outgoing long wave radiation(OLR),GPS/TEC,lower Earth orbit ionospheric tomography and critical frequency foF2.Our first results show that on March 7th a rapid increase of emitted infrared radiation was observed from the satellite data and an anomaly developed near the epicenter.The GPS/TEC data indicate an increase and variation in electron density reaching a maximum value on March 8.Starting from this day in the lower ionosphere also there was confirmed an abnormal TEC variation over the epicenter.From March 3 to 11 a large increase in electron concentration was recorded at all four Japanese ground-based ionosondes,which returned to normal after the main earthquake.The joint preliminary analysis of atmospheric and ionospheric parameters during the M9 Tohoku,Japan earthquake has revealed the presence of related variations of these parameters implying their connection with the earthquake process.This study may lead to a better understanding of the response of the atmosphere/ionosphere to the great Tohoku earthquake. | Dimitar Ouzounov Sergey Pulinets Alexey Romanov Alexander Romanov Konstantin Tsybulya Dmitri Davidenko Menas Kafatos Patrick Taylor | 2011 | Earthquake Science2011，24，6： | 7 |
| 3 | Estimation of effective plant area index for South Korean forests using LiDAR system显示文摘Light Detection and Ranging(LiDAR) systems can be used to estimate both vertical and horizontal forest structure.Woody components,the leaves of trees and the understory can be described with high precision,using geo-registered 3D-points.Based on this concept,the Effective Plant Area Indices(PAIe) for areas of Korean Pine(Pinus koraiensis),Japanese Larch(Larix leptolepis) and Oak(Quercus spp.) were estimated by calculating the ratio of intercepted and incident LIDAR laser rays for the canopies of the three forest types.Initially,the canopy gap fraction(GLiDAR) was generated by extracting the LiDAR data reflected from the canopy surface,or inner canopy area,using k-means statistics.The LiDAR-derived PAIe was then estimated by using GLIDAR with the Beer-Lambert law.A comparison of the LiDAR-derived and field-derived PAIe revealed the coefficients of determination for Korean Pine,Japanese Larch and Oak to be 0.82,0.64 and 0.59,respectively.These differences between field-based and LIDAR-based PAIe for the different forest types were attributed to the amount of leaves and branches in the forest stands.The absence of leaves,in the case of both Larch and Oak,meant that the LiDAR pulses were only reflected from branches.The probability that the LiDAR pulses are reflected from bare branches is low as compared to the reflection from branches with a high leaf density.This is because the size of the branch is smaller than the resolution across and along the 1 meter LIDAR laser track.Therefore,a better predictive accuracy would be expected for the model if the study would be repeated in late spring when the shoots and leaves of the deciduous trees begin to appear. | KWAK Doo-Ahn LEE Woo-Kyun KAFATOS Menas SON Yowhan CHO Hyun-Kook LEE Seung-Ho | 2010 | Science China(Life Sciences)2010，53，7： | 7 |
| 4 | Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals显示文摘AIM To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals.METHODS Transient elastography with controlled attenuation parameter(CAP) was used to assess hepatic steatosis post-sustained virological response(SVR);the CAP technology was not available in the United States at study initiation.Liver stiffness/fibrosis was measured before and 47 wk after treatment completion.Patients with genotype 3 and patients with cirrhosis were excluded.RESULTS One hundred and one patients were included in the study.Post-SVR there were decreases from baseline in alanine aminotransferase(ALT)(63.1 to 17.8 U/L),aspartate aminotransferase(51.8 to 21.5 U/L) and fibrosis score(7.4 to 6.1 k Pa)(P < 0.05).Post-SVR,48 patients(47.5%) had steatosis on CAP;of these,6.25% had advanced fibrosis.Patients with steatosis had higher body mass index(29.0 vs 26.1 kg/m2),glucose(107.8 vs 96.6 mg/d L),ALT(20.4 vs 15.3 mg/d L),CAP score(296.3 vs 212.4 d B/m) and fibrosis score(7.0 vs 5.3 k Pa);P < 0.05.Interestingly,compared to baseline,both patients with and without steatosis had change in fibrosis score post-SVR(7.7 k Pa vs 7.0 k Pa and 7.0 k Pa vs 5.3 k Pa);alternatively,(P < 0.05) and therefore patients with steatosis continued to have clinically significant stiffness(≥ 7 k Pa).CONCLUSION Fatty liver is very common in hepatitis C virus(HCV) patients post-SVR.These patients continue to have elevated mean fibrosis score(≥ 7 k Pa) compared to those without fatty liver;some have advanced fibrosis.Long term follow up is needed to assess steatosis and fibrosis in HCV patients post-SVR. | Mazen Noureddin Micaela M Wong Tsuyoshi Todo Shelly C Lu Arun J Sanyal Edward A Mena | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 5 | Neural Network-Based Second Order Reliability Method(NNBSORM)for Laminated Composite Plates in Free Vibration显示文摘Monte Carlo Simulations(MCS),commonly used for reliability analysis,require a large amount of data points to obtain acceptable accuracy,even if the Subset Simulation with Importance Sampling(SS/IS)methods are used.The Second Order Reliability Method(SORM)has proved to be an excellent rapid tool in the stochastic analysis of laminated composite structures,when compared to the slower MCS techniques.However,SORM requires differentiating the performance function with respect to each of the random variables involved in the simulation.The most suitable approach to do this is to use a symbolic solver,which renders the simulations very slow,although still faster than MCS.Moreover,the inability to obtain the derivative of the performance function with respect to some parameters,such as ply thickness,limits the capabilities of the classical SORM.In this work,a Neural Network-Based Second Order Reliability Method(NNBSORM)is developed to replace the finite element algorithm in the stochastic analysis of laminated composite plates in free vibration.Because of the ability to obtain expressions for the first and second derivatives of the NN system outputs with respect to any of its inputs,such as material properties,ply thicknesses and orientation angles,the need for using a symbolic solver to calculate the derivatives of the performance function no longer exists.The proposed approach is accordingly much faster,and easily allows for the consideration of ply thickness uncertainty.The present analysis showed that dealing with ply thicknesses as random variables results in 37%increase in the laminate’s probability of failure. | Mena E.Tawfik Peter L.Bishay Edward E.Sadek | 2018 | Computer Modeling in Engineering & Sciences2018，，4： | 3 |
| 6 | Interannual variability of vegetation over the Indian sub-continent and its relation to the different meteorological parameters显示文摘 | Sudipta Sarkar Menas Kafatos | 2004 | Remote Sensing of Environment2004，，2： | 2 |
| 7 | 体位性低血压的危险因素:老年男女存在差异显示文摘体位性低血压(orthostatic hypotension,OH)一般发生在站立后调节血压水平的机制发生变化以后。目前尚不清楚不同性别间OH的发生率和危险因素有何不同。本文旨在调查老年人OH患病率和危险因素的性别差异。方法:纳入来自委内瑞拉马拉开波老龄化研究的882名参与者。从仰卧位到站立位3 min后,收缩压持续下降≥20和(或)舒张压持续下降≥10 mm Hg(1 mm Hg=0.133 kPa)定义为OH。考虑到性别的交互作用和性别分层,研究者采用多因素Logistic回归模型评估男、女OH危险因素的相关性。 | Méndez AS Melgarejo JD Mena LJ Chávez CA González AC Boggia J Terwilliger JD Lee JH Maestre GE 陈云 叶鹏 | 2019 | 中华高血压杂志2019，27，6： | 2 |
| 8 | Minimally invasive spleen-preserving distal pancreatectomy: Does splenic vessel preservation have better postoperative outcomes? A systematic review and meta-analysis显示文摘BACKGROUND: Minimally invasive spleen-preserving distal pancreatectomy(SPDP) can be performed with either splenic vessel preservation(SVP) or resection [Warshaw procedure(WP)]. The aim of this study was to evaluate the postoperative clinical outcomes of patients undergoing both methods.DATA SOURCES: Database search of PubM ed, Embase, Scopus,Cochrane, and Google Scholar was performed(2000-2014); key bibliographies were reviewed. Qualified studies comparing patients undergoing SPDP with either SVP or WP, and assessing postoperative complications were included. Calculated pooled risk ratio(RR) with the corresponding 95% confidence interval(CI) by random effects methods were used in the meta-analyses. RESULTS: The search yielded 215 studies, of which only 14 observational studies met our selection criteria. The studies included 943 patients in total; 652(69%) underwent SVP and 291(31%) underwent WP. Overall, there was a lower incidence of splenic infarction(RR=0.17; 95% CI: 0.09-0.33; P<0.001),gastric varices(RR=0.16; 95% CI: 0.05-0.51; P=0.002), and intra/postoperative splenectomy(RR=0.20; 95% CI: 0.08-0.49; P<0.001) in the SVP group. There was no difference in incidence of pancreatic fistula(WP vs SVP, 23.6% vs 22.9%;P=0.37), length of hospital stay, operative time or blood loss. There was moderate cross-study heterogeneity.CONCLUSIONS: SVP is a safe, efficient and feasible technique that may be used to preserve the spleen. WP may be more suitable for large tumors close to the splenic hilum or those associated with splenomegaly. Randomized clinical trials are justified to examine the long-term benefits of SVP-SPDP. | Fady Elabbasy Rahul Gadde Mena M Hanna Danny Sleeman Alan Livingstone Danny Yakoub | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，4： | 2 |
| 9 | Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation显示文摘 | Jose A. Rodríguez-Navarro Laura Rodríguez María J. Casarejos Rosa M. Solano Ana Gómez Juan Perucho Ana María Cuervo Justo García de Yébenes María A. Mena | 2010 | Neurobiology of Disease2010，，3： | 2 |
| 10 | SSJD15011600007878显示文摘 | María A. Mejía-Benítez Amélie Bonnefond Lo?c Yengo Marlène Huyvaert Aurélie Dechaume Jesús Peralta-Romero Miguel Klünder-Klünder Jaime García Mena Julia S. El-Sayed Moustafa Mario Falchi Miguel Cruz Philippe Froguel | 2015 | Diabetologia2015，，2： | 2 |
| 11 | Toxic effects of L-DOPA on mesencephalic cell cultures: protection with antioxidants 显示文摘 | Mena MA Casarejos M J | 1995 | Brain Res1995，682，： | 1 |
| 12 | Neurotrophic effects of L-dopa in postnatal midbrain dopamine/cortical astrocyte co-cultures 显示文摘 | Mena MA Davila V Sulzer D | 1997 | J Neurochem1997，69，： | 1 |
| 13 | A reliable index for the prognostic significance of blood pressure variability显示文摘 | Mena L Pintos S Queipo NV | 2005 | J Hypertens2005，23，3： | 1 |
| 14 | State of the Art on Automatic Road Extraction for GIS Update: A Novel Classification 显示文摘 | Mena J B | 2003 | Pattern Recognition Letters2003，24，16： | 1 |
| 15 | Role for the DOF transcription factor BPBF in the regulation of gibber- ellin responsive genes in barley aleurone 显示文摘 | Mena M Cejudo F J Isabel-Lamoneda I | 2002 | Plant Physi- o12002，130，： | 1 |
| 16 | Using recombinant cox- sackievirus B3 to evaluate the induction and protective efficacy of CD8 + T cells during picomavirus infection显示文摘 | Slifka MK Pagarigan R Mena I | 2001 | J Virol2001，75，5： | 1 |
| 17 | A selective fluorescent probe for the detection of mercury(11) in aqueous media and its applications in living cells显示文摘 | Garcia-Beltran O Mena N Berrios T A | 2012 | Tetrahedron Letters2012，53，48： | 1 |
| 18 | Effect of solids on homogeneous-heterogeneous flow regime transition in bubble cohimns 显示文摘 | Mena P C Ruzicka M C Rocha F A | 2005 | Chemical Engineering Science2005，60，22： | 1 |
| 19 | A new role for reticulon-4B/NOGO- B in the intestinal epithelial barrier function and inflammatory bowel disease显示文摘 | Rodriguez-Feo JA Puerto M Fernandez- Mena C | 2015 | Am J Physiol Gastrointest Liver Physiol2015，308，2： | 1 |
| 20 | Recent developments in numerical modelling of subsurface flow constructed Wetlands显示文摘 | Langergraber G Giraldi D Mena J | 2009 | Sci Total Environ2009，407，5： | 1 |
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