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| 1 | A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value显示文摘 | Changsong Zou Aojun Chen Lihong Xiao Heike M Muller Peter Ache Georg Haberer Meiling Zhang Wei Jia Ping Deng Ru Huang Daniel Lang Feng Li Dongliang Zhan Xiangyun Wu Hui Zhang Jennifer Bohm Renyi Liu Sergey Shabala Rainer Hedrich Jian-Kang Zhu Heng Zhang | 2017 | Cell Research2017，27，11： | 22 |
| 2 | Generation of human haploid embryonic stem cells from parthenogenetic embryos obtained by microsurgical removal of male pronucleus显示文摘 | Cuiqing Zhong Meiling Zhang Qi Yin Han Zhao Yang Wang Sexin Huang Wenrong Tao Keliang Wu Zi-Jiang Chen Jinsong Li | 2016 | Cell Research2016，26，6： | 16 |
| 3 | Chromosome-scale genome assembly provides insights into the evolution and flavor synthesis of passion fruit (Passiflora edulis Sims)显示文摘Passion fruit(Passiflora edulis Sims)is an economically valuable fruit that is cultivated in tropical and subtropical regions of the world.Here,we report an~1341.7Mb chromosome-scale genome assembly of passion fruit,with 98.91%(~1327.18Mb)of the assembly assigned to nine pseudochromosomes.The genome includes 23,171 protein-coding genes,and most of the assembled sequences are repetitive sequences,with long-terminal repeats(LTRs)being the most abundant.Phylogenetic analysis revealed that passion fruit diverged after Brassicaceae and before Euphorbiaceae.Ks analysis showed that two whole-genome duplication events occurred in passion fruit at 65 MYA and 12 MYA,which may have contributed to its large genome size.An integrated analysis of genomic,transcriptomic,and metabolomic data showed that‘alpha-linolenic acid metabolism’,‘metabolic pathways’,and‘secondary metabolic pathways’were the main pathways involved in the synthesis of important volatile organic compounds(VOCs)in passion fruit,and this analysis identified some candidate genes,including GDP-fucose Transporter 1-like,Tetratricopeptide repeat protein 33,protein NETWORKED 4B isoform X1,and Golgin Subfamily A member 6-like protein 22.In addition,we identified 13 important gene families in fatty acid pathways and eight important gene families in terpene pathways.Gene family analysis showed that the ACX,ADH,ALDH,and HPL gene families,especially ACX13/14/15/20,ADH13/26/33,ALDH1/4/21,and HPL4/6,were the key genes for ester synthesis,while the TPS gene family,especially PeTPS2/3/4/24,was the key gene family for terpene synthesis.This work provides insights into genome evolution and flavor trait biology and offers valuable resources for the improved cultivation of passion fruit. | Zhiqiang Xia Dongmei Huang Shengkui Zhang Wenquan Wang Funing Ma Bin Wu Yi Xu Bingqiang Xu Di Chen Meiling Zou Huanyu Xu Xincheng Zhou Rulin Zhan Shun Song | 2021 | Horticulture Research2021，8，1： | 15 |
| 4 | The function of small RNAs in plant biotic stress response显示文摘Small RNAs(s RNAs) play essential roles in plants upon biotic stress. Plants utilize RNA silencing machinery to facilitate pathogen-associated molecular pattern-triggered immunity and effector-triggered immunity to defend against pathogen attack or to facilitate defense against insect herbivores. Pathogens, on the other hand, are also able to generate effectors and s RNAs to counter the host immune response. The arms race between plants and pathogens/insect herbivores has triggered the evolution of s RNAs,RNA silencing machinery and pathogen effectors. A great number of studies have been performed to investigate the roles of s RNAs in plant defense, bringing in the opportunity to utilize s RNAs in plant protection. Transgenic plants with pathogen-derived resistance ability or transgenerational defense have been generated, which show promising potential as solutions for pathogen/insect herbivore problems in the field. Here we summarize the recent progress on the function of s RNAs in response to biotic stress, mainly in plant-pathogen/insect herbivore interaction,and the application of s RNAs in disease and insect herbivore control. | Juan Huang Meiling Yang Xiaoming Zhang | 2016 | Journal of Integrative Plant Biology2016，58，4： | 9 |
| 5 | Design and Application of Water, Fertilizer and Pesticide Integrated Automatic Control Device显示文摘Integration of water, fertilizer and pesticide is the final stage of agricultural development, which improves the utilization efficiency of water, fertilizer and pesticide. Starting from the design and realization of water, fertilizer and pesticide integrated automatic control device, the paper discusses selection and application of fertilizer pesticides, use procedure, water, fertilizer and pesticide saving effect and receptive crowd in the application process of modern planting industry, so as to provide the basis for promotion and popularization of water, fertilizer and pesticide integration. | Huang Wei Lu Meiling Liang Xin Zhu Yulin Wang Daobo | 2020 | Plant Diseases and Pests2020，11，1： | 4 |
| 6 | The effects of altered BMP4 signaling in first branchialarch- derived murine embryonic orofacial tissues显示文摘The first branchial arch(BA1),which is derived from cranial neural crest(CNC)cells,gives rise to various orofacial tissues.Cre mice are widely used for the determination of CNC and exploration of gene functions in orofacial development.However,there is a lack of Cre mice specifically marked BA1’s cells.Pax2-Cre allele was previously generated and has been widely used in the field of inner ear development.Here,by compounding Pax2-Cre and R26R-mTmG mice,we found a specific expression pattern of Pax2^(+)cells that marked BA1’s mesenchymal cells and the BA1-derivatives.Compared to Pax2-Cre;R26R-mTmG allele,GFP^(+)cells were abundantly found both in BA1 and second branchial arch in Wnt1-Cre;R26R-mTmG mice.As BMP4 signaling is required for orofacial development,we over-activated Bmp4 by using Pax2-Cre;pMes-BMP4 strain.Interestingly,our results showed bilateral hyperplasia between the upper and lower teeth.We also compare the phenotypes of Wnt1-Cre;pMes-BMP4 and Pax2-Cre;pMes-BMP4 strains and found severe deformation of molar buds,palate,and maxilla-mandibular bony structures in Wnt1-Cre;pMes-BMP4 mice;however,the morphology of these orofacial organs were comparable between controls and Pax2-Cre;pMes-BMP4 mice except for bilateral hyperplastic tissues.We further explore the properties of the hyperplastic tissue and found it is not derived from Runx2^(+)cells but expresses Msx1,and probably caused by abnormal cell proliferation and altered expression pattern of p-Smad1/5/8.In sum,our findings suggest altering BMP4 signaling in BA1-specific cell lineage may lead to unique phenotypes in orofacial regions,further hinting that Pax2-Cre mice could be a new model for genetic manipulation of BA1-derived organogenesis in the orofacial region. | Jue Xu Meiling Chen Yanan Yan Qiaoxue Zhao Meiying Shao Zhen Huang | 2021 | International Journal of Oral Science2021，13，4： | 3 |
| 7 | Development and Application of Special Fertilizer for Crops in Guangxi Region显示文摘Different crops need different kinds of nutrients. In this paper,formula of special fertilizer for common field crops in Guangxi is explored from the angle of grain crops,fruits,vegetables,sugar crops,oil crops,etc.,and corresponding production equipment and methods are provided,which could convenience for agricultural precision fertilization and theoretical basis and technical reference for cost saving and efficiency increasing of fertilizer. | Wei HUANG Meiling LU Xin LIANG Yulin ZHU Daobo WANG | 2020 | Meteorological and Environmental Research2020，11，2： | 2 |
| 8 | Simultaneous direct analysis of benzimidazole fungicides and relevant metabolites in agricultural products based on multifunction dispersive solid-phase extraction and liquid chromatography–mass spectrometry显示文摘 | Bin Guo Zhiqiang Huang Meiling Wang Xiaoying Wang Ying Zhang Bo Chen Yongjun Li Hongfei Yan Shouzhuo Yao | 2010 | Journal of Chromatography A2010，，29： | 1 |
| 9 | A multicentre randomised trial comparing weekly paclitaxel<ce:hsp sp='0.25'/>+<ce:hsp sp='0.25'/>S-1 with weekly paclitaxel<ce:hsp sp='0.25'/>+<ce:hsp sp='0.25'/>5-fluorouracil for patients with advanced gastric cancer显示文摘 | Dingzhi Huang Yi Ba Jianping Xiong Nong Xu Zhao Yan Zhixiang Zhuang Zhuang Yu Huiping Wan Yang Zhang Ting Deng Rongsheng Zheng Zengqing Guo Chunhong Hu Meiling Wang Zhonghe Yu Yang Yao Jichang Meng | 2013 | European Journal of Cancer2013，，： | 1 |
| 10 | IncR26319/miR-2834/EndophilinA axis regulates oogenesis of the silkworm,Bombyx mori显示文摘Oocyte maturation is critical for insect reproduction.Vitellogenesis,the timely production and uptake of vitellogenin(Vg),is crucial for female fecundity.Vg is synthesized in fat body and absorbed by the oocytes through endocytosis during insect oogenesis.In the silkworm,Bombyx mori,we discovered that a nucleus-enriched long-noncoding RNA(lncRNA)lncR26319 regulates Endophilin A(EndoA)-a member of the endophilin family of endocytic proteins-through competitive binding to miR-2834.The lncR26319-miR-2834-EndoA axis was required for Vg endocytosis in the silkworm;loss of EndoA or overexpression ofmiR-2834significantlyreduced eggnumbers invirginmoths.Inaddition,accumulation of miR-2834 resulted in pupal and adult deformation and reduced fecundity in females.The expression of Vg,30-kDa(30K)protein,and egg-specific protein(Esp)decreased after knockdown of EndoA or overexpression of miR-2834,while knockdown of miR-2834 had an opposite effect on the expression of Vg,30K protein gene,and Esp.These results suggest that the lncR26319-miR-2834-EndoA axis contributes to the endocytic activity in theVguptake and leads to the normal progression of oogenesis in the silkworm.Thus,miR-2834 and EndoA are crucial for female reproduction and could be potential targets for new pest management strategies in lepidopterans. | Yi Wang Yu Fu Hao Chena Chenyue Zhao Qunxia Huang Meiling Chang Wujie Qiu Yawen Shen Dandan Li | 2023 | Insect Science2023，30，1： | 1 |
| 11 | Strong invariance principles for arrays显示文摘 | LI Deli HUANG Meiling ROSALSKYA | 2000 | Bull Inst Math Acad Sinica2000，28，： | 1 |
| 12 | Measurements of indoor thermal environment and energy analysis in a large space building in typical seasnns 显示文摘 | Chen Huang Zhijun Zou Meiling Li | 2007 | Building and Environment2007，42，5： | 1 |
| 13 | Synthesis of nickel nanoparticles dispersed in γ-alumina by heterogeneous precipitation显示文摘 | LI GUO-JUN HUANG XIAO-XIAN RUAN MEILING | 2002 | Ceramics International2002，28，2： | 1 |
| 14 | Heterogeneous nuclear ribonuclear protein K interacts with the entero- virus 71 5runtranslated region and participates in virus replication显示文摘 | Lin Jingyi Li Meiling Huang Pengnien Chien Kun Yi Horng Jim Tong Shih Shin Ru | 2008 | J Gen Virol2008，89，10： | 1 |
| 15 | Measurements of indoor thermal environment and energy analysis in a large space building in typical seasons 显示文摘 | Chen Huang Zhijun Zou Meiling Li | 2007 | Building and Environment2007，42，5： | 1 |
| 16 | Immunochromatographic Assay for Ultrasensitive Detection of Aflatoxiu B1 in Maize by Highly Luminescent Quantum Dot Beads显示文摘 | Meiling Ren Hengyi Xu Xiaolin Huang | 2014 | American Chemical Society2014，6，14： | 1 |
| 17 | Analysis and Enlightenment on Continuation of Spatial Image of Traditional Streets and Lanes in Historical Urban Area:A Case Study of Spatial Design of Traditional Streets and Lanes in Xin’gan South Road of Ganzhou City显示文摘Traditional block of Xin’gan South Road in Ganzhou City is taken as the research object.Using urban design techniques,spatial structure,spatial interface,scale,ratio and spatial node of traditional streets and lanes are controlled and processed,and spatial image is analyzed.Moreover,the strategic transformation proposal is put forward.It promotes the renewal of traditional streets and lanes in urban renewal,and realizes the historical continuation of spatial image of traditional streets and lanes,thereby protecting the historical features of the ancient city. | GUO Song HUANG Meiling LI Zhi | 2020 | Journal of Landscape Research2020，12，6： | 1 |
| 18 | Accelerating C_(2+)alcohols synthesis from syngas by simultaneous optimizations of CO dissociation and chain growth over CuCo alloy catalyst显示文摘With regard to the reaction of higheralcohol synthesis(HAS),the optimizations of activity and selectivity towards C_(2+)alcohol are restricted by the improper equilibrium in two different CO activation pathways and chain growth capacity.Herein,we find that delibrately controlling the compositions of catalysts is an effective strategy to achieve the equilibrium of CO activation pathways and promote the chain growth.As a result,the optimized Cu_(0.25)Co_(0.75) alloy catalyst can achieve a large proportion of higher alcohol in alcohol products(C_(2+)OH/MeOH=4.40),together with high CO conversion of 71.27%and space-time-yield of 147.65 g kg^(-1) h^(-1).The mechanistic studies suggest that the good performance of Cu_(0.25)Co_(0.75) catalyst is attributed to the synergistic effect between alloyed Cu and Co. | Meiling Shui Chao Huang Peiyu Ma Wenjie Li Qun He Wenlong Wu Yisheng Tan Jun Bao | 2021 | Chinese Chemical Letters2021，32，7： | 1 |
| 19 | Measurements of indoor thermal environment and energy analysis in a large space building in typical seasons显示文摘 | Huang Chen Zou Zhijun Li Meiling | 2007 | Building and Environment2007，42，5： | 1 |
| 20 | Cell-free DNA derived from cancer cells facilitates tumor malignancy through Toll-like receptor 9 signaling-triggered interleukin-8 secretion in colorectal cancer显示文摘 | Zhengchuan Niu Wentao Tang Tianyu Liu Pingping Xu Dexiang Zhu Meiling Ji Wenbai Huang Li Ren Ye Wei Jianmin Xu | 2018 | Acta Biochimica et Biophysica Sinica2018，50，10： | 1 |
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